A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells

Circadian Disruption and Diet-Induced Obesity Synergize to Promote Development of β-Cell Failure and Diabetes in Male Rats

(2015) Jingyi Qian et al.   ENDOCRINOLOGY

Circadian timing of metabolism in animal models and humans

(2015) C. Dibner et al.   JOURNAL OF INTERNAL MEDICINE

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

(2015) Christopher J. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic   cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

(2015) M. Perelis et al.   SCIENCE

The human transcriptome across tissues and individuals

(2015) M. Mele et al.   SCIENCE

Human Peripheral Clocks: Applications for Studying Circadian Phenotypes in Physiology and Pathophysiology

(2015) Camille Saini et al.   Frontiers in Neurology

Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion

(2015) Laurent Perrin et al.   Molecular Metabolism

Circadian Clocks and Feeding Time Regulate the Oscillations and Levels of Hepatic Triglycerides

(2014) Yaarit Adamovich et al.   Cell Metabolism

Zinc transporter 8 (ZnT8) and β cell function

(2014) Howard W. Davidson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Role of the Endocrine System in Feeding-Induced Tissue-Specific Circadian Entrainment

(2014) Miho Sato et al.   Cell Reports

Circadian control of glucose metabolism

(2014) Andries Kalsbeek et al.   Molecular Metabolism

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

(2013) Miriam Cnop et al.   DIABETES

Consequences of Exposure to Light at Night on the Pancreatic Islet Circadian Clock and Function in Rats

(2013) J. Qian et al.   DIABETES

Circadian Clock Characteristics Are Altered in Human Thyroid Malignant Nodules

(2013) Tiphaine Mannic et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans

(2013) E. C.-P. Chua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of the mammalian circadian clock

(2013) Carrie L. Partch et al.   TRENDS IN CELL BIOLOGY

Islet Autoantigens: Structure, Function, Localization, and Regulation

(2013) P. Arvan et al.   Cold Spring Harbor Perspectives in Medicine

Autonomous and self-sustained circadian oscillators displayed in human islet cells

(2012) P. Pulimeno et al.   DIABETOLOGIA

Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators

(2012) C. Saini et al.   GENES & DEVELOPMENT

Regulation of core clock genes in human islets

(2012) Jelena A. Stamenkovic et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

(2012) Yukimasa Takeda et al.   NUCLEIC ACIDS RESEARCH

The human circadian metabolome

(2012) R. Dallmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rotational co-culture of clonal β-cells with endothelial cells: effect of PPAR-γ agonism in vitro on insulin and VEGF secretion

(2011) M. B. Paget et al.   DIABETES OBESITY & METABOLISM

Disruption of Circadian Rhythms Accelerates Development of Diabetes through Pancreatic Beta-Cell Loss and Dysfunction

(2011) John E. Gale et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells

(2011) Jeongkyung Lee et al.   Islets

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

JTK_CYCLE: An Efficient Nonparametric Algorithm for Detecting Rhythmic Components in Genome-Scale Data Sets

(2010) Michael E. Hughes et al.   JOURNAL OF BIOLOGICAL RHYTHMS

The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice

(2010) Antonia Sassmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

Noninvasive method for assessing the human circadian clock using hair follicle cells

(2010) M. Akashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Molecular insights into human daily behavior

(2008) S. A. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics