Identification of Small Molecule Activators of Cryptochrome

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Circadian Gene Variants and Susceptibility to Type 2 Diabetes: A Pilot Study

(2012) M. Ann Kelly et al.   PLoS One

A Small Molecule Modulates Circadian Rhythms through Phosphorylation of the Period Protein

(2011) Jae Wook Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function

(2011) Maki Ukai-Tadenuma et al.   CELL

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

(2011) Laura A Solt et al.   Future Medicinal Chemistry

An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing

(2011) Tim Sonntag et al.   Molecular BioSystems

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

(2011) Katja A. Lamia et al.   NATURE

Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening

(2011) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DYRK1A and Glycogen Synthase Kinase 3 , a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping

(2010) N. Kurabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

(2010) Tsuyoshi Hirota et al.   PLOS BIOLOGY

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

High-Throughput Screening and Chemical Biology: New Approaches for Understanding Circadian Clock Mechanisms

(2009) Tsuyoshi Hirota et al.   CHEMISTRY & BIOLOGY

Roles of CLOCK Phosphorylation in Suppression of E-Box-Dependent Transcription

(2009) H. Yoshitane et al.   MOLECULAR AND CELLULAR BIOLOGY

Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

(2009) Rongmin Chen et al.   MOLECULAR CELL

Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes

(2009) K. Hitomi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A model of the cell-autonomous mammalian circadian clock

(2009) H. P. Mirsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CKI / -dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

(2009) Y. Isojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensitivity Analysis for Oscillating Dynamical Systems

(2009) A. Katharina Wilkins et al.   SIAM JOURNAL ON SCIENTIFIC COMPUTING

The Meter of Metabolism

(2008) Carla B. Green et al.   CELL

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3 

(2008) T. Hirota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In silicoactivity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

(2008) David Plouffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA