标题
Islet biology, the CDKN2A/B locus and type 2 diabetes risk
作者
关键词
Ageing, <em class=EmphasisTypeItalic >ANRIL</em>, Beta cell mass, <em class=EmphasisTypeItalic >Cdkn2A</em>, <em class=EmphasisTypeItalic >Cdkn2B</em>, <em class=EmphasisTypeItalic >CDKN2B-AS</em>, Insulin secretion, Oncogene, p14, p14<sup>ARF</sup>, p15, p15<sup>INK4B</sup>, p16, p16<sup>INK4A</sup>, Pancreatic beta cell, Proliferation, Review, Senescence, Tumour suppressor
出版物
DIABETOLOGIA
Volume 59, Issue 8, Pages 1579-1593
出版商
Springer Nature
发表日期
2016-05-07
DOI
10.1007/s00125-016-3967-7
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Association study of the miRNA-binding site polymorphisms of CDKN2A/B genes with gestational diabetes mellitus susceptibility
- (2015) Xiaojing Wang et al. ACTA DIABETOLOGICA
- Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function
- (2015) Dana Avrahami et al. Cell Metabolism
- Loss-of-Function Mutations in the Cell-Cycle Control GeneCDKN2AImpact on Glucose Homeostasis in Humans
- (2015) Aparna Pal et al. DIABETES
- Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant atCCND2Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion
- (2015) Hanieh Yaghootkar et al. DIABETES
- Bisphenol-A Treatment During Pregnancy in Mice: A New Window of Susceptibility for the Development of Diabetes in Mothers Later in Life
- (2015) Paloma Alonso-Magdalena et al. ENDOCRINOLOGY
- Diabetes susceptibility in Mayas: Evidence for the involvement of polymorphisms in HHEX, HNF4α, KCNJ11, PPARγ, CDKN2A/2B, SLC30A8, CDC123/CAMK1D, TCF7L2, ABCA1 and SLC16A11 genes
- (2015) J.C. Lara-Riegos et al. GENE
- CDK4 is an essential insulin effector in adipocytes
- (2015) Sylviane Lagarrigue et al. JOURNAL OF CLINICAL INVESTIGATION
- Epigenetic linkage of aging, cancer and nutrition
- (2015) M. Daniel et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2
- (2015) Ming-de Huang et al. Journal of Hematology & Oncology
- Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs?
- (2015) Sarah Anissa Hannou et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- TOX and CDKN2A/B Gene Polymorphisms Are Associated with Type 2 Diabetes in Han Chinese
- (2015) Fengjiang Wei et al. Scientific Reports
- CDKN2B expression and subcutaneous adipose tissue expandability: Possible influence of the 9p21 atherosclerosis locus
- (2014) Per-Arne Svensson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Interaction of type 2 diabetes mellitus with Chromosome 9p21 rs10757274 polymorphism on the risk of myocardial infarction: a case–control study in Chinese population
- (2014) Liu-wei Zhang et al. BMC Cardiovascular Disorders
- Genetic polymorphisms in the 9p21 region associated with risk of multiple cancers
- (2014) W.-Q. Li et al. CARCINOGENESIS
- Fine Mapping of Type 2 Diabetes Susceptibility Loci
- (2014) Andrew P. Morris Current Diabetes Reports
- Lipotoxicity in the Pancreatic Beta Cell: Not Just Survival and Function, but Proliferation as Well?
- (2014) Rohit B. Sharma et al. Current Diabetes Reports
- Differential Transcriptome Analysis of Diabetes-Resistant and -Sensitive Mouse Islets Reveals Significant Overlap With Human Diabetes Susceptibility Genes
- (2014) O. Kluth et al. DIABETES
- Reduced Ki67 Staining in the Postmortem State Calls Into Question Past Conclusions About the Lack of Turnover of Adult Human β-Cells
- (2014) Brooke A. Sullivan et al. DIABETES
- Cdkn2a/p16Ink4a Regulates Fasting-Induced Hepatic Gluconeogenesis Through the PKA-CREB-PGC1 Pathway
- (2014) K. Bantubungi et al. DIABETES
- Gender-dependent associations of CDKN2A/2B, KCNJ11, POLI, SLC30A8, and TCF7L2 variants with type 2 diabetes in (North African) Tunisian Arabs
- (2014) Amira Turki et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Genetic variants for type 2 diabetes and new-onset cancer in Chinese with type 2 diabetes
- (2014) R.C.W. Ma et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Dorothy Hodgkin Lecture 2014Understanding genes identified by genome-wide association studies for Type 2 diabetes
- (2014) G. A. Rutter DIABETIC MEDICINE
- Disease-associated polymorphisms in 9p21 are not associated with extreme longevity
- (2014) Ada Congrains et al. Geriatrics & Gerontology International
- Long Noncoding RNA ANRIL Promotes Non-Small Cell Lung Cancer Cell Proliferation and Inhibits Apoptosis by Silencing KLF2 and P21 Expression
- (2014) F.-q. Nie et al. MOLECULAR CANCER THERAPEUTICS
- Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression
- (2014) Yoonjin Lee et al. NATURE
- Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
- (2014) Valgerdur Steinthorsdottir et al. NATURE GENETICS
- Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
- (2014) Lorenzo Pasquali et al. NATURE GENETICS
- Deletions of RDINK4/ARF Enhancer in Gastrinomas and Nonfunctioning Pancreatic Neuroendocrine Tumors
- (2014) Ming J. Poi et al. PANCREAS
- Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
- (2014) J. Fadista et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Ink4a/Arf Locus in Beta Cell Mass Expansion under Physiological and Pathological Conditions
- (2014) Elisabet Salas et al. Journal of Diabetes Research
- PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a
- (2013) Ni Zeng et al. AGING CELL
- Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression
- (2013) Rachel E. Stamateris et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Evidence that P12, a specific variant of P16INK4A, plays a suppressive role in human pancreatic carcinogenesis
- (2013) Ming J. Poi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of Common Genetic Variants Associated With Type 2 Diabetes and Glycemic Traits on α- and β-Cell Function and Insulin Action in Humans
- (2013) Anna Jonsson et al. DIABETES
- Human Pancreatic -Cell G1/S Molecule Cell Cycle Atlas
- (2013) N. M. Fiaschi-Taesch et al. DIABETES
- Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human -Cell Replication: A Revised Model of Human -Cell G1/S Control
- (2013) N. M. Fiaschi-Taesch et al. DIABETES
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- (2013) Seth J. Salpeter et al. DIABETES
- Genetic Modifiers of Cystic Fibrosis-Related Diabetes
- (2013) S. M. Blackman et al. DIABETES
- Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity
- (2013) Antigone S. Dimas et al. DIABETES
- Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice
- (2013) Kai-Ting Yang et al. DIABETOLOGIA
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- (2013) A. Moreno-Asso et al. DIABETOLOGIA
- Search for genetic determinants of sulfonylurea efficacy in type 2 diabetic patients from China
- (2013) Qian Ren et al. DIABETOLOGIA
- TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass
- (2013) Iseki Takamoto et al. DIABETOLOGIA
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- (2013) T. A. Dayeh et al. DIABETOLOGIA
- Trans-ethnic fine mapping identifies a novel independent locus at the 3′ end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population
- (2013) Jane Z. Kuo et al. DIABETOLOGIA
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- (2013) Feng Peng et al. GENE
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- (2013) Shiv K Singh et al. GUT
- The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10
- (2013) Gregor Bochenek et al. HUMAN MOLECULAR GENETICS
- ANRIL: Molecular Mechanisms and Implications in Human Health
- (2013) Ada Congrains et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Clinical and Genetic Risk Factors for Type 2 Diabetes at Early or Late Post Partum After Gestational Diabetes Mellitus
- (2013) Soo Heon Kwak et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The role of aging upon β cell turnover
- (2013) Jake A. Kushner JOURNAL OF CLINICAL INVESTIGATION
- Combined modulation of polycomb and trithorax genes rejuvenates β cell replication
- (2013) Josie X. Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- CDKN2Bexpression in adipose tissue of familial combined hyperlipidemia patients
- (2013) Stuart D. Horswell et al. JOURNAL OF LIPID RESEARCH
- Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes
- (2013) Jalal Taneera et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
- (2013) S. C. J. Parker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of β-cell replication by a synthetic HNF4α antagonist
- (2013) Seung-Hee Lee et al. STEM CELLS
- Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese
- (2013) Hiroki Mizukami et al. Journal of Diabetes Investigation
- Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks
- (2013) Lesca M. Holdt et al. PLoS Genetics
- Re-thinking cell cycle regulators: the cross-talk with metabolism
- (2013) Lluis Fajas Frontiers in Oncology
- Increased dosage ofInk4/Arfprotects against glucose intolerance and insulin resistance associated with aging
- (2012) Herminia González-Navarro et al. AGING CELL
- Review: a meta-analysis of GWAS and age-associated diseases
- (2012) William R. Jeck et al. AGING CELL
- Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population
- (2012) Francesca Gori et al. BMC Medical Genetics
- Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15)
- (2012) Gijs WD Landman et al. Cardiovascular Diabetology
- Molecular Profiling of Pancreatic Neuroendocrine Tumors in Sporadic and Von Hippel-Lindau Patients
- (2012) D. Speisky et al. CLINICAL CANCER RESEARCH
- Contribution of Common Genetic Variation to the Risk of Type 2 Diabetes in the Mexican Mestizo Population
- (2012) M. A. Gamboa-Melendez et al. DIABETES
- ChREBP Mediates Glucose-Stimulated Pancreatic -Cell Proliferation
- (2012) M. R. Metukuri et al. DIABETES
- Free Fatty Acids Block Glucose-Induced -Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18
- (2012) J. Pascoe et al. DIABETES
- A Genome-Wide Association Study IdentifiesGRK5andRASGRP1as Type 2 Diabetes Loci in Chinese Hans
- (2012) Huaixing Li et al. DIABETES
- European genetic variants associated with type 2 diabetes in North African Arabs
- (2012) S. Cauchi et al. DIABETES & METABOLISM
- -Cell Mass and Turnover in Humans: Effects of obesity and aging
- (2012) Y. Saisho et al. DIABETES CARE
- Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men
- (2012) S. C. Jacobsen et al. DIABETOLOGIA
- SNP in the genome-wide association study hotspot on chromosome 9p21 confers susceptibility to diabetic nephropathy in type 1 diabetes
- (2012) E. Fagerholm et al. DIABETOLOGIA
- Analysis of common type 2 diabetes mellitus genetic risk factors in new-onset diabetes after transplantation in kidney transplant patients medicated with tacrolimus
- (2012) Mateusz Kurzawski et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Bmi1 Is Required for Regeneration of the Exocrine Pancreas in Mice
- (2012) Akihisa Fukuda et al. GASTROENTEROLOGY
- Pancreatic Beta Cells in Very Old Mice Retain Capacity for Compensatory Proliferation
- (2012) Miri Stolovich-Rain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life
- (2012) Brigid E. Gregg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography
- (2012) Kikuko Hotta et al. JOURNAL OF HUMAN GENETICS
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- Activation of Protein Kinase C- in Pancreatic -Cells In Vivo Improves Glucose Tolerance and Induces -Cell Expansion via mTOR Activation
- (2011) S. Velazquez-Garcia et al. DIABETES
- Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations
- (2011) S. D. Rees et al. DIABETOLOGIA
- Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype
- (2011) L. Fuentes et al. DIABETOLOGIA
- Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B
- (2011) M. L. Hribal et al. DIABETOLOGIA
- Systemic and acute administration of parathyroid hormone-related peptide(1–36) stimulates endogenous beta cell proliferation while preserving function in adult mice
- (2011) K. Williams et al. DIABETOLOGIA
- Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs
- (2011) V. Gupta et al. DIABETOLOGIA
- Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas
- (2011) E. J. Parra et al. DIABETOLOGIA
- Glucose Regulates Cyclin D2 Expression in Quiescent and Replicating Pancreatic β-Cells Through Glycolysis and Calcium Channels
- (2011) Seth J. Salpeter et al. ENDOCRINOLOGY
- Common genetic variants associated with open-angle glaucoma
- (2011) Wishal D. Ramdas et al. HUMAN MOLECULAR GENETICS
- 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response
- (2011) Olivier Harismendy et al. NATURE
- E2F transcription factor-1 regulates oxidative metabolism
- (2011) Emilie Blanchet et al. NATURE CELL BIOLOGY
- Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction
- (2011) Jessica Shea et al. NATURE GENETICS
- Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1
- (2011) Kathryn P Burdon et al. NATURE GENETICS
- p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors
- (2011) C Romagosa et al. ONCOGENE
- Hyperglycemia-Induced Proliferation of Adult Human Beta Cells Engrafted Into Spontaneously Diabetic Immunodeficient NOD-Rag1null IL2rγnull Ins2Akita Mice
- (2011) Philip diIorio et al. PANCREAS
- Correction: Identifying and Characterizing Nodes Important to Community Structure Using the Spectrum of the Graph
- (2011) Yang Wang et al. PLoS One
- Clinical translation of genetic predictors for type 2 diabetes
- (2011) Amit R Majithia et al. Current Opinion in Endocrinology Diabetes and Obesity
- Cell cycle control of β-cell replication in the prenatal and postnatal human pancreas
- (2010) Christina U. Köhler et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in Type 2 Diabetes in a Chinese population
- (2010) Xueyao Han et al. BMC Medical Genetics
- Glycemia Determines the Effect of Type 2 Diabetes Risk Genes on Insulin Secretion
- (2010) M. Heni et al. DIABETES
- Decreased IRS Signaling Impairs -Cell Cycle Progression and Survival in Transgenic Mice Overexpressing S6K in -Cells
- (2010) L. Elghazi et al. DIABETES
- Cyclin D2 Is Essential for the Compensatory -Cell Hyperplastic Response to Insulin Resistance in Rodents
- (2010) S. Georgia et al. DIABETES
- Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6
- (2010) Nathalie M. Fiaschi-Taesch et al. DIABETES
- Impact of Common Variants ofPPARG,KCNJ11,TCF7L2,SLC30A8,HHEX,CDKN2A,IGF2BP2, andCDKAL1on the Risk of Type 2 Diabetes in 5,164 Indians
- (2010) Ganesh Chauhan et al. DIABETES
- Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass
- (2010) G. Fontés et al. DIABETOLOGIA
- Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD–severe combined immunodeficiency (SCID) mice
- (2010) H. E. Levitt et al. DIABETOLOGIA
- Expression analysis of loci associated with type 2 diabetes in human tissues
- (2010) C. Cotsapas et al. DIABETOLOGIA
- Epigenetic regulation of theINK4b-ARF-INK4alocus
- (2010) Nikolay Popov et al. Epigenetics
- ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS
- (2010) Eric Pasmant et al. FASEB JOURNAL
- Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined byin VivoThymidine Analog Incorporation and Radiocarbon Dating
- (2010) S. Perl et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Replication of recently described type 2 diabetes gene variants in a South Indian population
- (2010) Manickam Chidambaram et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a
- (2010) Kyoko L. Yap et al. MOLECULAR CELL
- Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice
- (2010) Axel Visel et al. NATURE
- A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese
- (2010) Satoko Uno et al. NATURE GENETICS
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
- (2010) Benjamin F Voight et al. NATURE GENETICS
- Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene
- (2010) Y Kotake et al. ONCOGENE
- Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression
- (2010) Michael S. Cunnington et al. PLoS Genetics
- Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke
- (2009) Andreas Gschwendtner et al. ANNALS OF NEUROLOGY
- Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus
- (2009) Olga Jarinova et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Disproportionate Hyperproinsulinemia, β-Cell Restricted Prohormone Convertase 2 Deficiency, and Cell Cycle Inhibitors Expression by Human Islets Transplanted into Athymic Nude Mice: Insights into Nonimmune-Mediated Mechanisms of Delayed Islet Graft Failure
- (2009) Alberto M. Davalli et al. CELL TRANSPLANTATION
- p38MAPK Controls Expression of Multiple Cell Cycle Inhibitors and Islet Proliferation with Advancing Age
- (2009) Esther Sook Miin Wong et al. DEVELOPMENTAL CELL
- Age-Dependent Decline in -Cell Proliferation Restricts the Capacity of -Cell Regeneration in Mice
- (2009) S.-I. Tschen et al. DIABETES
- Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First-Phase Glucose-Stimulated Insulin Secretion During Hyperglycemic Clamps
- (2009) L. M. 't Hart et al. DIABETES
- Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach
- (2009) J. R.B. Perry et al. DIABETES
- Previously Associated Type 2 Diabetes Variants May Interact With Physical Activity to Modify the Risk of Impaired Glucose Regulation and Type 2 Diabetes: A Study of 16,003 Swedish Adults
- (2009) E. C. Brito et al. DIABETES
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- (2009) F. Takeuchi et al. DIABETES
- Adaptive -Cell Proliferation Is Severely Restricted With Advanced Age
- (2009) M. M. Rankin et al. DIABETES
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- (2009) N. Fiaschi-Taesch et al. DIABETES
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- (2009) S. M. Raj et al. DIABETOLOGIA
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- (2009) N. Pulizzi et al. DIABETOLOGIA
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- (2009) S.-M. Ruchat et al. DIABETOLOGIA
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- (2009) J. L. Tarry-Adkins et al. FASEB JOURNAL
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- (2009) S. Dhawan et al. GENES & DEVELOPMENT
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- (2009) H. Chen et al. GENES & DEVELOPMENT
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- (2009) Norman Balcazar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Axel Haupt et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2009) Jonathan T. Tan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2009) Lu Mei He et al. MOLECULAR ENDOCRINOLOGY
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- (2009) Jean-Sébastien Annicotte et al. NATURE CELL BIOLOGY
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- (2009) Enzo Emanuele et al. NEUROBIOLOGY OF AGING
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- (2009) Juan R. Lopez et al. NEUROENDOCRINOLOGY
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- (2009) Hanane Agherbi et al. PLoS One
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- (2009) Lasse Folkersen et al. PLoS One
- Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis
- (2009) E. Sangiorgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association of Common Type 2 Diabetes Risk Gene Variants and Posttransplantation Diabetes Mellitus in Renal Allograft Recipients in Korea
- (2009) Eun Seok Kang et al. TRANSPLANTATION
- Identification of a Shared Genetic Susceptibility Locus for Coronary Heart Disease and Periodontitis
- (2009) Arne S. Schaefer et al. PLoS Genetics
- New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function
- (2008) John RB Perry et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Replication Study of Candidate Genes Associated With Type 2 Diabetes Based On Genome-Wide Screening
- (2008) Y. Tabara et al. DIABETES
- Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program
- (2008) A. F. Moore et al. DIABETES
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- (2008) I. Cozar-Castellano et al. DIABETES
- Association Analysis of Type 2 Diabetes Loci in Type 1 Diabetes
- (2008) H.-Q. Qu et al. DIABETES
- Predicting Type 2 Diabetes Based on Polymorphisms From Genome-Wide Association Studies: A Population-Based Study
- (2008) M. van Hoek et al. DIABETES
- Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians
- (2008) M. C.Y. Ng et al. DIABETES
- -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of -Cell Mass in Humans
- (2008) J. J. Meier et al. DIABETES
- Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids
- (2008) K. Duesing et al. DIABETOLOGIA
- Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion
- (2008) K. Kirchhoff et al. DIABETOLOGIA
- Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps
- (2008) M. J. Groenewoud et al. DIABETOLOGIA
- Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population
- (2008) Y. M. Cho et al. DIABETOLOGIA
- Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes
- (2008) Jeannet Lauenborg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
- (2008) Yong-Ho Lee et al. JOURNAL OF HUMAN GENETICS
- Whole Genome Analyses Suggest Ischemic Stroke and Heart Disease Share an Association With Polymorphisms on Chromosome 9p21
- (2008) Mar Matarin et al. STROKE
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