PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a

Glucose Regulates Cyclin D2 Expression in Quiescent and Replicating Pancreatic β-Cells Through Glycolysis and Calcium Channels

(2011) Seth J. Salpeter et al.   ENDOCRINOLOGY

Adaptive Basal Phosphorylation of eIF2  Is Responsible for Resistance to Cellular Stress-Induced Cell Death in Pten-Null Hepatocytes

(2011) N. Zeng et al.   MOLECULAR CANCER RESEARCH

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis

(2011) Alyssa L. Kennedy et al.   MOLECULAR CELL

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

(2011) Hainan Chen et al.   NATURE

Glucose and aging control the quiescence period that follows pancreatic beta cell replication

(2010) S. J. Salpeter et al.   DEVELOPMENT

Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic  -Cell Death and Accelerates the Onset of Diabetes

(2010) J. Mellado-Gil et al.   DIABETES

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

(2010) Andrea Alimonti et al.   JOURNAL OF CLINICAL INVESTIGATION

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

The Retinoblastoma Protein and Its Homolog p130 Regulate the G1/S Transition in Pancreatic  -Cells

(2009) G. Harb et al.   DIABETES

Spontaneous Recovery of Streptozotocin Diabetes in Mice

(2009) K. Hartmann et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Bmi-1 regulates the Ink4a/Arf locus to control pancreatic  -cell proliferation

(2009) S. Dhawan et al.   GENES & DEVELOPMENT

Polycomb protein Ezh2 regulates pancreatic  -cell Ink4a/Arf expression and regeneration in diabetes mellitus

(2009) H. Chen et al.   GENES & DEVELOPMENT

Polycomb Mediated Epigenetic Silencing and Replication Timing at the INK4a/ARF Locus during Senescence

(2009) Hanane Agherbi et al.   PLoS One

Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation

(2008) Z. Liu et al.   DIABETOLOGIA

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice

(2008) J. Agudo et al.   DIABETOLOGIA

PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex

(2008) A. Woiwode et al.   MOLECULAR AND CELLULAR BIOLOGY

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

(2008) Katsuya Tanabe et al.   PLOS BIOLOGY