TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass
出版年份 2013 全文链接
标题
TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass
作者
关键词
Beta cell proliferation, Dominant-negative form, Insulin production, Insulin secretion, <em class=EmphasisTypeItalic >TCF7L2</em>, Wnt/β-catenin signalling
出版物
DIABETOLOGIA
Volume 57, Issue 3, Pages 542-553
出版商
Springer Nature
发表日期
2013-12-07
DOI
10.1007/s00125-013-3131-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand
- (2012) Sylvia F. Boj et al. CELL
- Dominant-negative isoforms of Tcf/Lef proteins in development and disease
- (2012) Tomas Vacik et al. CELL CYCLE
- Cell-Context Dependent TCF/LEF Expression and Function: Alternative Tales of Repression, De-Repression and Activation Potentials
- (2012) Catherine D. Mao et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- The Wnt Signaling Pathway Effector TCF7L2 Controls Gut and Brain Proglucagon Gene Expression and Glucose Homeostasis
- (2012) W. Shao et al. DIABETES
- Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice
- (2012) G. da Silva Xavier et al. DIABETOLOGIA
- Reduction in Tcf7l2 Expression Decreases Diabetic Susceptibility in Mice
- (2012) Hyekyung Yang et al. International Journal of Biological Sciences
- FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization
- (2012) Osamu Kikuchi et al. PLoS One
- TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver
- (2012) Kyoung-Jin Oh et al. PLoS Genetics
- Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism
- (2011) L. Norton et al. DIABETOLOGIA
- An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes
- (2011) J. M. Locke et al. DIABETOLOGIA
- A novel mechanism for the transcriptional regulation of Wnt signaling in development
- (2011) T. Vacik et al. GENES & DEVELOPMENT
- Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
- (2011) D. Savic et al. GENOME RESEARCH
- TCF7L2 splice variants have distinct effects on β-cell turnover and function
- (2011) Olivier Le Bacquer et al. HUMAN MOLECULAR GENETICS
- MafA and MafB activity in pancreatic β cells
- (2011) Yan Hang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas
- (2010) Joshua Columbus et al. JOURNAL OF ENDOCRINOLOGY
- A map of open chromatin in human pancreatic islets
- (2010) Kyle J Gaulton et al. NATURE GENETICS
- A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B
- (2010) Toshimasa Yamauchi et al. NATURE GENETICS
- The what, where, when and how of Wnt/β-catenin signaling in pancreas development
- (2010) L. Charles Murtaugh Organogenesis
- Role of MafA in pancreatic β-cells
- (2009) Hideaki Kaneto et al. ADVANCED DRUG DELIVERY REVIEWS
- TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action
- (2009) D. T. Villareal et al. DIABETES
- Lack of β-catenin in early life induces abnormal glucose homeostasis in mice
- (2009) S. Dabernat et al. DIABETOLOGIA
- Unique splicing pattern of the TCF7L2 gene in human pancreatic islets
- (2009) P. Osmark et al. DIABETOLOGIA
- Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
- (2009) Luan Shu et al. HUMAN MOLECULAR GENETICS
- Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia
- (2009) Hoang Nguyen et al. NATURE GENETICS
- Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding
- (2008) Naoto Kubota et al. Cell Metabolism
- The WNT signalling pathway and diabetes mellitus
- (2008) T. Jin DIABETOLOGIA
- Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation
- (2008) Zhengyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wnt signaling: relevance to β-cell biology and diabetes
- (2008) Hannah J. Welters et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started