Is the C-C Motif Ligand 2–C-C Chemokine Receptor 2 Axis a Promising Target for Cancer Therapy and Diagnosis?
出版年份 2020 全文链接
标题
Is the C-C Motif Ligand 2–C-C Chemokine Receptor 2 Axis a Promising Target for Cancer Therapy and Diagnosis?
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 23, Pages 9328
出版商
MDPI AG
发表日期
2020-12-08
DOI
10.3390/ijms21239328
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes
- (2020) Thomas M. Pausch et al. Scientific Reports
- Increased Vascular Adhesion Protein 1 (VAP-1) Levels Are Associated with Alternative M2 Macrophage Activation and Poor Prognosis for Human Gliomas
- (2020) Shu-Jyuan Chang et al. Diagnostics
- Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small-Cell Lung Carcinoma
- (2020) Xiang Zheng et al. CANCER RESEARCH
- The CCL20-CCR6 Axis in Cancer Progression
- (2020) Suguru Kadomoto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumor Cells Interleukin-22 Expression Associates with Elevated Tumor-Associated Macrophages Infiltrating and Poor Prognosis in Patients with Breast Cancer
- (2020) Jidong Zhao et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Targeting a positive regulatory loop in the tumor-macrophage interaction impairs the progression of clear cell renal cell carcinoma
- (2020) Chao Wang et al. CELL DEATH AND DIFFERENTIATION
- Prognostic significance of tumor-associated macrophages in patients with nasopharyngeal carcinoma
- (2020) Ya-Lian Chen MEDICINE
- Prognostic value of some inflammatory markers in patients with lymphoma
- (2019) Nahla Hamed Anber et al. BIOSCIENCE REPORTS
- The Angiotensin Receptor Blocker Losartan Suppresses Growth of Pulmonary Metastases via AT1R-Independent Inhibition of CCR2 Signaling and Monocyte Recruitment
- (2019) Daniel P. Regan et al. JOURNAL OF IMMUNOLOGY
- CCL2 promotes cell migration by inducing epithelial‐mesenchymal transition in oral squamous cell carcinoma
- (2019) Zihang Ling et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma
- (2019) Marcus Noel et al. INVESTIGATIONAL NEW DRUGS
- PIPKIγ Regulates CCL2 Expression in Colorectal Cancer by Activating AKT-STAT3 Signaling
- (2019) JunLi Xue et al. Journal of Immunology Research
- Serum levels of the chemokine CCL2 are elevated in malignant pleural mesothelioma patients
- (2019) Takumi Kishimoto et al. BMC CANCER
- Tumor‐associated macrophages secrete CC‐chemokine ligand 2 and induce tamoxifen resistance by activating PI3K/Akt/mTOR in breast cancer
- (2019) Dongbo Li et al. CANCER SCIENCE
- Interleukin‐33‐nuclear factor‐κB‐CCL2 signaling pathway promotes progression of esophageal squamous cell carcinoma by directing regulatory T cells
- (2019) Ying Yue et al. CANCER SCIENCE
- Myeloid-Derived Suppressor Cells: Major Figures that Shape the Immunosuppressive and Angiogenic Network in Cancer
- (2019) Eleni-Kyriaki Vetsika et al. Cells
- Androgen deprivation therapy-induced epithelial-mesenchymal transition of prostate cancer through downregulating SPDEF and activating CCL2
- (2018) Yuan-Chin Tsai et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A guide to chemokines and their receptors
- (2018) Catherine E. Hughes et al. FEBS Journal
- CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer
- (2018) Wenxia Xu et al. International Journal of Biological Sciences
- Overall survival in a trial of orally administered CCR2 inhibitor CCX872 in locally advanced/metastatic pancreatic cancer: Correlation with blood monocyte counts.
- (2018) David Linehan et al. JOURNAL OF CLINICAL ONCOLOGY
- Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration
- (2018) Bianca Cioni et al. Molecular Oncology
- CCL2 influences the sensitivity of lung cancer A549 cells to docetaxel
- (2018) Ting Wang et al. Oncology Letters
- High levels of CCL2 or CCL4 in the tumor microenvironment predict unfavorable survival in lung adenocarcinoma
- (2018) Lei Li et al. Thoracic Cancer
- Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients
- (2018) Erin E. Talbert et al. Journal of Cachexia Sarcopenia and Muscle
- Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer
- (2018) Julie G Grossman et al. OncoImmunology
- Prognostic significance of monocyte chemoattractant protein-1 and CC chemokine receptor 2 in diffuse large B cell lymphoma
- (2018) Yan-Li Li et al. ANNALS OF HEMATOLOGY
- CCL2 induces resistance to the antiproliferative effect of cabazitaxel in prostate cancer cells
- (2018) Ariunbold Natsagdorj et al. CANCER SCIENCE
- CCL2 is a vascular permeability factor inducing CCR2-dependent endothelial retraction during lung metastasis
- (2018) Marko Roblek et al. MOLECULAR CANCER RESEARCH
- Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells
- (2018) Hiroaki Iwamoto et al. PROSTATE
- High expression of CCL2 in tumor cells and abundant infiltration with CD14 positive macrophages predict early relapse in breast cancer
- (2018) Marja Heiskala et al. VIRCHOWS ARCHIV
- Perioperative cytokine levels portend early death after pancreatectomy for ductal adenocarcinoma
- (2017) Heather L. Lewis et al. JOURNAL OF SURGICAL ONCOLOGY
- CCL2 expression correlates with Snail expression and affects the prognosis of patients with gastric cancer
- (2017) Jia Zhang et al. PATHOLOGY RESEARCH AND PRACTICE
- Targeting CCR2 with its antagonist suppresses viability, motility and invasion by downregulating MMP-9 expression in non-small cell lung cancer cells
- (2017) Jun An et al. Oncotarget
- FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
- (2016) Xuguang Yang et al. CANCER RESEARCH
- Elevated level of some chemokines in plasma of gastric cancer patients
- (2016) Monika Baj-Krzyworzeka et al. Central European Journal of Immunology
- Tumor-Derived CCL2 Mediates Resistance to Radiotherapy in Pancreatic Ductal Adenocarcinoma
- (2016) Anusha Kalbasi et al. CLINICAL CANCER RESEARCH
- Combination of IL-6, IL-10, and MCP-1 with traditional serum tumor markers in lung cancer diagnosis and prognosis
- (2016) Y.W. Pan et al. GENETICS AND MOLECULAR RESEARCH
- Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
- (2016) Timothy M Nywening et al. LANCET ONCOLOGY
- Elevated expression of chemokine C-C ligand 2 in stroma is associated with recurrent basal-like breast cancers
- (2016) Min Yao et al. MODERN PATHOLOGY
- CCL2/CCR2 axis is associated with postoperative survival and recurrence of patients with non-metastatic clear-cell renal cell carcinoma
- (2016) Zewei Wang et al. Oncotarget
- CCL2/EGF positive feedback loop between cancer cells and macrophages promotes cell migration and invasion in head and neck squamous cell carcinoma
- (2016) Lu Gao et al. Oncotarget
- Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22–CCR4 axis
- (2016) Aerken Maolake et al. Oncotarget
- CCL2 as a potential therapeutic target for clear cell renal cell carcinoma
- (2016) Ryuichiro Arakaki et al. Cancer Medicine
- Elevated circulating monocyte chemoattractant protein 1 (MCP-1/CCL-2) level may be an unfavorable predictive factor to platinum- and taxane-based combination chemotherapy in patients with gastric cancer
- (2015) Faruk Tas et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages
- (2015) Takanori Kitamura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Macrophages and cancer: from mechanisms to therapeutic implications
- (2015) Renato Ostuni et al. TRENDS IN IMMUNOLOGY
- Increased expression of C-C motif ligand 2 associates with poor prognosis in patients with gastric cancer after gastrectomy
- (2015) Hao Liu et al. TUMOR BIOLOGY
- Serum chemokine (CC motif) ligand 2 level as a diagnostic, predictive, and prognostic biomarker for prostate cancer
- (2015) Kouji Izumi et al. Oncotarget
- Recruited mast cells in the tumor microenvironment enhance bladder cancer metastasis via modulation of ERβ/CCL2/CCR2 EMT/MMP9 signals
- (2015) Qun Rao et al. Oncotarget
- CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function
- (2015) Eunyoung Chun et al. Cell Reports
- Chemokine Receptor-Specific Antibodies in Cancer Immunotherapy: Achievements and Challenges
- (2015) Maria Vela et al. Frontiers in Immunology
- Fibroblast heterogeneity in the cancer wound
- (2014) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers
- (2014) Francois Moisan et al. Molecular Oncology
- Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
- (2014) Laura Bonapace et al. NATURE
- A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
- (2014) Haihui Lu et al. NATURE CELL BIOLOGY
- The CCL2/CCR2 axis enhances IL-6-induced epithelial-mesenchymal transition by cooperatively activating STAT3-Twist signaling
- (2014) Wei Chen et al. TUMOR BIOLOGY
- Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia
- (2014) Lei-Lei Tao WORLD JOURNAL OF GASTROENTEROLOGY
- A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
- (2013) Shahneen K. Sandhu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis
- (2013) D. E. Sanford et al. CLINICAL CANCER RESEARCH
- Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
- (2013) Kouji Izumi et al. EMBO Molecular Medicine
- Identification of Serum Monocyte Chemoattractant Protein-1 and Prolactin as Potential Tumor Markers in Hepatocellular Carcinoma
- (2013) Who-Whong Wang et al. PLoS One
- Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling
- (2013) T-H Lin et al. Cell Death & Disease
- Regulation of Monocyte Chemoattractant Protein-1 Through Angiotensin II Type 1 Receptor in Prostate Cancer
- (2012) Suguru Shirotake et al. AMERICAN JOURNAL OF PATHOLOGY
- Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway
- (2012) Monika Julia Wolf et al. CANCER CELL
- CCL2 is critical for immunosuppression to promote cancer metastasis
- (2012) Chie Kudo-Saito et al. CLINICAL & EXPERIMENTAL METASTASIS
- Autocrine CCL2 promotes cell migration and invasion via PKC activation and tyrosine phosphorylation of paxillin in bladder cancer cells
- (2012) Hsiao-Ying Chiu et al. CYTOKINE
- Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes
- (2012) Jun Panee CYTOKINE
- Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer
- (2012) Kenneth J. Pienta et al. INVESTIGATIONAL NEW DRUGS
- The monocyte chemoattractant protein-1 (MCP-1)/CCR2 system is involved in peritoneal dialysis-related epithelial–mesenchymal transition of peritoneal mesothelial cells
- (2012) Sun Ha Lee et al. LABORATORY INVESTIGATION
- Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature
- (2012) Qiong-wen Zhang et al. PLoS One
- CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-κB signaling pathway
- (2011) Chih-Hsin Tang et al. BIOCHEMICAL PHARMACOLOGY
- Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma
- (2011) Valerie Chew et al. GUT
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Macrophage chemotactic protein-1 mRNA levels in non-Hodgkin lymphoma
- (2010) Toni Valković et al. CLINICAL AND EXPERIMENTAL MEDICINE
- Serum CCL2 and serum TNF-α – Two new biomarkers predict bone invasion, post-treatment distant metastasis and poor overall survival in nasopharyngeal carcinoma
- (2010) Xing Lu et al. EUROPEAN JOURNAL OF CANCER
- Tumor Cell-Microenvironment Interaction Models Coupled with Clinical Validation Reveal CCL2 and SNCG as Two Predictors of Colorectal Cancer Hepatic Metastasis
- (2009) H. Hu et al. CLINICAL CANCER RESEARCH
- Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells
- (2009) Maylis Dagouassat et al. INTERNATIONAL JOURNAL OF CANCER
- Significance of monocyte chemoattractant protein-1 in angiogenesis and survival in colorectal liver metastases
- (2009) Yoshidome INTERNATIONAL JOURNAL OF ONCOLOGY
- Angiotensin II Regulates the Expression of Monocyte Chemoattractant Protein-1 in Pancreatic Cancer Cells
- (2009) Navdeep Chehl et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Monocyte Chemoattractant Protein-1 (MCP-1): An Overview
- (2009) Satish L. Deshmane et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity
- (2009) David Z. Qian et al. PROSTATE
- The Expression of Monocyte Chemotactic Protein-1 in Papillary Thyroid Carcinoma Is Correlated with Lymph Node Metastasis and Tumor Recurrence
- (2008) Katsuhiro Tanaka et al. THYROID
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