Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation

The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis through Macrophage and Osteoclast Recruitment

(2015) Kosuke Mizutani et al.   NEOPLASIA

The effect of matrix metalloproteinase 2 and matrix metalloproteinase 2/9 deletion in experimental post-thrombotic vein wall remodeling

(2013) Kristopher B. Deatrick et al.   JOURNAL OF VASCULAR SURGERY

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells

(2012) Soo Ok Lee et al.   Journal of Molecular Cell Biology

Cancer statistics, 2011

(2011) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Castration-resistant prostate cancer: Many treatments, many options, many challenges ahead

(2011) Jorge A. Garcia et al.   CANCER

Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1

(2011) Changmeng Cai et al.   CANCER CELL

Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

(2011) David J. Mulholland et al.   CANCER CELL

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

(2011) Brett S. Carver et al.   CANCER CELL

Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy

(2011) Y. Sun et al.   CANCER RESEARCH

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Overcoming Persistent Dependency on Androgen Signaling after Progression to Castration-Resistant Prostate Cancer

(2010) M. Yamaoka et al.   CLINICAL CANCER RESEARCH

Multiple Roles of Chemokine (C-C Motif) Ligand 2 in Promoting Prostate Cancer Growth

(2010) J. Zhang et al.   JNCI-Journal of the National Cancer Institute

B-cell-derived lymphotoxin promotes castration-resistant prostate cancer

(2010) Massimo Ammirante et al.   NATURE

Urokinase plasminogen activator independent early experimental thrombus resolution: MMP2 as an alternative mechanism

(2010) Vikram Sood et al.   THROMBOSIS AND HAEMOSTASIS

CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis

(2009) Jian Zhang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells

(2009) Meng-Lei Zhu et al.   FASEB JOURNAL

Src-dependent STAT-3-mediated Expression of Monocyte Chemoattractant Protein-1 Is Required for 15(S)-Hydroxyeicosatetraenoic Acid-induced Vascular Smooth Muscle Cell Migration

(2009) Harihara S. K. Potula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-α expression

(2009) Jiann-Jyh Lai et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3

(2009) P Kaler et al.   ONCOGENE

Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

(2009) William P Harris et al.   Nature clinical practice. Urology

Stat3 Promotes Metastatic Progression of Prostate Cancer

(2008) Junaid Abdulghani et al.   AMERICAN JOURNAL OF PATHOLOGY

Synthesis and evaluation of cis-3,4-disubstituted piperidines as potent CC chemokine receptor 2 (CCR2) antagonists

(2008) Robert J. Cherney et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists

(2008) Robert J. Cherney et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

(2008) Y. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA