Cancer associated fibroblast mediated chemoresistance: A paradigm shift in understanding the mechanism of tumor progression
出版年份 2020 全文链接
标题
Cancer associated fibroblast mediated chemoresistance: A paradigm shift in understanding the mechanism of tumor progression
作者
关键词
Tumor microenvironment, Cancer-associated fibroblasts, Chemoresistance, Tumor progression, Therapy
出版物
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1874, Issue 2, Pages 188416
出版商
Elsevier BV
发表日期
2020-08-19
DOI
10.1016/j.bbcan.2020.188416
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling
- (2019) Fernanda G. Kugeratski et al. Science Signaling
- Current perspectives of cancer-associated fibroblast in therapeutic resistance: potential mechanism and future strategy
- (2019) Dhruba Kadel et al. CELL BIOLOGY AND TOXICOLOGY
- Cancer-associated fibroblasts promote cisplatin resistance in bladder cancer cells by increasing IGF-1/ERβ/Bcl-2 signalling
- (2019) Xingbo Long et al. Cell Death & Disease
- Cancer-Associated Fibroblasts Build and Secure the Tumor Microenvironment
- (2019) Tianyi Liu et al. Frontiers in Cell and Developmental Biology
- Coping with chemoresistance in prostate cancer—co-targeting of adipose stromal cells?
- (2019) Divya Bhagirath et al. Translational Andrology and Urology
- Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy
- (2019) Tongyan Liu et al. Journal of Hematology & Oncology
- The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment
- (2019) Lea Monteran et al. Frontiers in Immunology
- Cancer-associated fibroblasts confer cisplatin resistance of tongue cancer via autophagy activation
- (2018) Juan-kun Liao et al. BIOMEDICINE & PHARMACOTHERAPY
- Pro-survival autophagy and cancer cell resistance to therapy
- (2018) Chandan Kanta Das et al. CANCER AND METASTASIS REVIEWS
- CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
- (2018) Shicheng Su et al. CELL
- Fibroblast heterogeneity: implications for human disease
- (2018) Magnus D. Lynch et al. JOURNAL OF CLINICAL INVESTIGATION
- Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer
- (2018) Lucy Ireland et al. ONCOGENE
- Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors
- (2018) Magdolna Djurec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
- (2018) Aurélie S. Cazet et al. Nature Communications
- Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
- (2018) Jing Ren et al. Theranostics
- Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming
- (2018) Rajeev Mishra et al. JOURNAL OF CLINICAL INVESTIGATION
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts
- (2018) Yuan Zhou et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers
- (2018) Chandan Kanta Das et al. MOLECULAR PHARMACEUTICS
- Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
- (2018) Shuang Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance
- (2018) Fei Chen et al. Nature Communications
- Chemoresistance and the Self-Maintaining Tumor Microenvironment
- (2018) Gulcen Yeldag et al. Cancers
- The role of exosomes and miRNAs in drug-resistance of cancer cells
- (2017) Duc-Hiep Bach et al. INTERNATIONAL JOURNAL OF CANCER
- The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer
- (2017) Dimakatso Alice Senthebane et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- High-mobility group box 1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells
- (2017) Xi-Long Zhao et al. JOURNAL OF PATHOLOGY
- DNA damage response-initiated cytokine secretion in bone marrow stromal cells promotes chemoresistance of myeloma cells
- (2017) Hailong Tang et al. LEUKEMIA & LYMPHOMA
- JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non–Small Cell Lung Cancer
- (2017) Kazuhiko Shien et al. MOLECULAR CANCER THERAPEUTICS
- Circulating and disseminated tumor cells: harbingers or initiators of metastasis?
- (2017) Arko Dasgupta et al. Molecular Oncology
- Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts
- (2017) Josep Baulida Molecular Oncology
- DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells
- (2017) C Pistore et al. ONCOGENE
- DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment
- (2017) P Mathot et al. Oncogenesis
- Developmental and Functional Control of Natural Killer Cells by Cytokines
- (2017) Yang Wu et al. Frontiers in Immunology
- Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model
- (2017) Janina Kuen et al. PLoS One
- A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment
- (2017) Neha Nair et al. Scientific Reports
- The hypoxic tumor microenvironment: A driving force for breast cancer progression
- (2016) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Hypoxia-activated prodrugs: paths forward in the era of personalised medicine
- (2016) Francis W Hunter et al. BRITISH JOURNAL OF CANCER
- Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors
- (2016) Lucy Ireland et al. CANCER RESEARCH
- Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress
- (2016) Qian Wang et al. CELL CYCLE
- Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer
- (2016) S. R. Hingorani et al. CLINICAL CANCER RESEARCH
- Cancer chemoresistance; biochemical and molecular aspects: a brief overview
- (2016) Saeed Kachalaki et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells
- (2016) Tze-Sian Chan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CAFs and TAMs: maestros of the tumour microenvironment
- (2016) Yoshihiro Komohara et al. JOURNAL OF PATHOLOGY
- Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets
- (2016) Yufang Shi et al. NATURE REVIEWS DRUG DISCOVERY
- Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion
- (2016) T T Vellinga et al. ONCOGENE
- Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance
- (2016) T Yu et al. ONCOGENE
- Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells
- (2016) K E Richards et al. ONCOGENE
- Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1
- (2016) Pedro Barcellos-de-Souza et al. STEM CELLS
- Neutrophils in the Tumor Microenvironment
- (2016) Davalyn R. Powell et al. TRENDS IN IMMUNOLOGY
- Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth
- (2016) Marco Gerling et al. Nature Communications
- Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1
- (2016) Chi Lam Au Yeung et al. Nature Communications
- Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer
- (2016) Keisuke Yamamoto et al. Oncotarget
- Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance
- (2016) Alessia Fidoamore et al. Stem Cells International
- Targeting breast cancer-associated fibroblasts to improve anti-cancer therapy
- (2015) Astrid Slany et al. BREAST
- Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells
- (2015) A. Lo et al. CANCER RESEARCH
- Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis
- (2015) C. D. Madsen et al. EMBO REPORTS
- Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma
- (2015) Timothy J Underwood et al. JOURNAL OF PATHOLOGY
- Translational Horizons in the Tumor Microenvironment: Harnessing Breakthroughs and Targeting Cures
- (2015) Yu Sun MEDICINAL RESEARCH REVIEWS
- Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment
- (2015) H Tian et al. ONCOGENE
- Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
- (2015) Kazuyoshi Shiga et al. Cancers
- Fibroblast-Derived Exosomes Contribute to Chemoresistance through Priming Cancer Stem Cells in Colorectal Cancer
- (2015) Yibing Hu et al. PLoS One
- Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors
- (2015) Constantin Jotzu et al. Analytical Cellular Pathology
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- MET Signaling in Colon Cancer Stem-like Cells Blunts the Therapeutic Response to EGFR Inhibitors
- (2014) Paolo Luraghi et al. CANCER RESEARCH
- VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation
- (2014) A. Fantozzi et al. CANCER RESEARCH
- Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion
- (2014) Xiaojun Chen et al. CARCINOGENESIS
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways
- (2014) Mirjam C. Boelens et al. CELL
- TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells
- (2014) Horacio Cardenas et al. Epigenetics
- Overexpression of NRG1 promotes progression of gastric cancer by regulating the self-renewal of cancer stem cells
- (2014) Myoung-Eun Han et al. JOURNAL OF GASTROENTEROLOGY
- Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer
- (2014) C E Weber et al. ONCOGENE
- TGF- -inducible microRNA-183 silences tumor-associated natural killer cells
- (2014) S. S. Donatelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer
- (2014) Peter Bronsert et al. SURGERY
- The IL-6–STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression
- (2014) Q Zhu et al. Cell Death & Disease
- Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment
- (2014) Martin Augsten Frontiers in Oncology
- Role of Macrophage Targeting in the Antitumor Activity of Trabectedin
- (2013) Giovanni Germano et al. CANCER CELL
- Retinoic acid inhibits pancreatic cancer cell migration and EMT through the downregulation of IL-6 in cancer associated fibroblast cells
- (2013) Jian Guan et al. CANCER LETTERS
- TGF- Modulates Ovarian Cancer Invasion by Upregulating CAF-Derived Versican in the Tumor Microenvironment
- (2013) T.-L. Yeung et al. CANCER RESEARCH
- Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients
- (2013) Mercedes Herrera et al. CANCER SCIENCE
- Cancer cell bioenergetics and pH regulation influence breast cancer cell resistance to paclitaxel and doxorubicin
- (2013) Diana Tavares-Valente et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Hepatic stellate cells in liver development, regeneration, and cancer
- (2013) Chunyue Yin et al. JOURNAL OF CLINICAL INVESTIGATION
- Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A
- (2013) Fiorenza Lotti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines
- (2013) A Vultur et al. ONCOGENE
- Candidate Markers That Associate with Chemotherapy Resistance in Breast Cancer through the Study on Taxotere-Induced Damage to Tumor Microenvironment and Gene Expression Profiling of Carcinoma-Associated Fibroblasts (CAFs)
- (2013) Guohua Rong et al. PLoS One
- Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
- (2013) X Sui et al. Cell Death & Disease
- Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
- (2013) Vikash P. Chauhan et al. Nature Communications
- Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis
- (2013) Younghun Jung et al. Nature Communications
- Tumoral Immune Suppression by Macrophages Expressing Fibroblast Activation Protein- and Heme Oxygenase-1
- (2013) J. N. Arnold et al. Cancer Immunology Research
- Fibroblasts as architects of cancer pathogenesis
- (2012) Timothy Marsh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
- (2012) B. Hu et al. CANCER RESEARCH
- The Tumor Stroma as Mediator of Drug Resistance - A Potential Target to Improve Cancer Therapy?
- (2012) Susanne Sebens et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Cancer-associated fibroblasts and CD163-positive macrophages in oral squamous cell carcinoma: their clinicopathological and prognostic significance
- (2012) Nobuyuki Fujii et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Cancer-Associated Fibroblasts Induce Matrix Metalloproteinase-Mediated Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cells
- (2012) A.-C. Johansson et al. MOLECULAR CANCER RESEARCH
- Activation of IL-6R/JAK1/STAT3 Signaling Induces De Novo Resistance to Irreversible EGFR Inhibitors in Non-Small Cell Lung Cancer with T790M Resistance Mutation
- (2012) S. M. Kim et al. MOLECULAR CANCER THERAPEUTICS
- Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
- (2012) Yu Sun et al. NATURE MEDICINE
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Modulating autophagy: a strategy for cancer therapy
- (2012) Jun-Lin Li et al. Chinese Journal of Cancer
- Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
- (2011) Paolo Cirri et al. CANCER AND METASTASIS REVIEWS
- Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells
- (2011) Ubaldo E. Martinez-Outschoorn et al. CANCER BIOLOGY & THERAPY
- Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
- (2011) Tuanjie Li et al. CANCER LETTERS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities
- (2011) Fen Yang et al. EMBO JOURNAL
- Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
- (2011) S. E. Polo et al. GENES & DEVELOPMENT
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- The Role of Tumour Stroma in Colorectal Cancer Invasion and Metastasis
- (2011) John Conti et al. Cancers
- Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
- (2010) Neta Erez et al. CANCER CELL
- Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model
- (2010) Yuan Wen et al. CANCER SCIENCE
- Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution
- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1
- (2010) Yiwei Lin et al. EMBO JOURNAL
- Stromal issues in cervical cancer: a review of the role and function of basement membrane, stroma, immune response and angiogenesis in cervical cancer development
- (2010) Shaira Sahebali et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model
- (2010) Tomonori Sumida et al. INTERNATIONAL JOURNAL OF CANCER
- ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
- (2010) E Sánchez-Tilló et al. ONCOGENE
- Autocrine TGF- and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
- (2010) Y. Kojima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-
- (2010) M. Kraman et al. SCIENCE
- EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells
- (2009) Peter Camaj et al. BIOLOGICAL CHEMISTRY
- Anti-Apoptotic Mechanisms of Drug Resistance in Cancer
- (2009) T. Wilson et al. CURRENT CANCER DRUG TARGETS
- Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis
- (2009) Adrian M. Jubb et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Snail1 Protein in the Stroma as a New Putative Prognosis Marker for Colon Tumours
- (2009) Clara Francí et al. PLoS One
- Low stroma androgen receptor level in normal and tumor prostate tissue is related to poor outcome in prostate cancer patients
- (2009) Pernilla Wikström et al. PROSTATE
- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
- (2009) K. P. Olive et al. SCIENCE
- Cancer associated fibroblasts in cancer pathogenesis
- (2009) Omar E. Franco et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells
- (2008) P. J. Mishra et al. CANCER RESEARCH
- Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts
- (2008) C. Anderberg et al. CANCER RESEARCH
- Nuclear factor-κB dependency of doxorubicin sensitivity in gastric cancer cells is determined by manganese superoxide dismutase expression
- (2008) Sung Jin Cho et al. CANCER SCIENCE
- Modulated expression of WFDC1 during carcinogenesis and cellular senescence
- (2008) Shalom Madar et al. CARCINOGENESIS
- Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer
- (2008) J. M. Bailey et al. CLINICAL CANCER RESEARCH
- Genomic Instability and Carcinogenesis: An Update
- (2008) Wael Abdel-Rahman CURRENT GENOMICS
- The tumor microenvironment and its contribution to tumor evolution toward metastasis
- (2008) Girieca Lorusso et al. HISTOCHEMISTRY AND CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started