Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity

(2017) Juan R. Hernandez-Fernaud et al.   Nature Communications

Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis

(2016) Sayantan Maji et al.   MOLECULAR CANCER RESEARCH

Mass-spectrometric exploration of proteome structure and function

(2016) Ruedi Aebersold et al.   NATURE

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury

(2016) Weilin Zhang et al.   eLife

Rapid High-pH Reverse Phase StageTip for Sensitive Small-Scale Membrane Proteomic Profiling

(2015) Baby Rorielyn T. Dimayacyac-Esleta et al.   ANALYTICAL CHEMISTRY

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

(2015) C. D. Madsen et al.   EMBO REPORTS

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

(2015) Thomas R. Cox et al.   NATURE

The PHD2 oxygen sensor paves the way to metastasis

(2015) Anna Kuchnio et al.   Oncotarget

Endotrophin – Linking Obesity with Aggressive Tumor Growth

(2015) Jiyoung Park et al.   Oncotarget

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The impact of KRAS mutations on VEGF-A production and tumour vascular network

(2013) Agnès Figueras et al.   BMC CANCER

Lysyl oxidase-like-2 promotes tumour angiogenesis and is a potential therapeutic target in angiogenic tumours

(2013) Shelly Zaffryar-Eilot et al.   CARCINOGENESIS

Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts

(2013) Daniele M. Gilkes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment

(2013) A Casazza et al.   ONCOGENE

Loss of Fibroblast HIF-1  Accelerates Tumorigenesis

(2012) J.-w. Kim et al.   CANCER RESEARCH

Next-generation proteomics: towards an integrative view of proteome dynamics

(2012) A. F. Maarten Altelaar et al.   NATURE REVIEWS GENETICS

The Proteomics Identifications (PRIDE) database and associated tools: status in 2013

(2012) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis and metastasis

(2012) G L Semenza   ONCOGENE

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

(2011) M. Bignon et al.   BLOOD

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells

(2010) Barbara Chiavarina et al.   CELL CYCLE

Hypoxia Activates the K-Ras Proto-Oncogene to Stimulate Angiogenesis and Inhibit Apoptosis in Colon Cancer Cells

(2010) Min Zeng et al.   PLoS One

Autocrine TGF-  and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

(2010) Y. Kojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combination of FASP and StageTip-Based Fractionation Allows In-Depth Analysis of the Hippocampal Membrane Proteome

(2009) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

K-Ras Promotes Angiogenesis Mediated by Immortalized Human Pancreatic Epithelial Cells through Mitogen-Activated Protein Kinase Signaling Pathways

(2009) Y. Matsuo et al.   MOLECULAR CANCER RESEARCH

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

(2009) M. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortactin: Coordinating adhesion and the actin cytoskeleton at cellular protrusions

(2009) Gang Ren et al.   CELL MOTILITY AND THE CYTOSKELETON

Mass spectrometry for proteomics

(2008) Xuemei Han et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Characterization of the anti-angiogenic properties of arresten, an α1β1 integrin-dependent collagen-derived tumor suppressor

(2008) Pia Nyberg et al.   EXPERIMENTAL CELL RESEARCH

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE