标题
Targeting Akt-associated microRNAs for cancer therapeutics
作者
关键词
Akt, Biomarkers, Cancer, RNA-therapeutics, MicroRNAs
出版物
BIOCHEMICAL PHARMACOLOGY
Volume -, Issue -, Pages 114384
出版商
Elsevier BV
发表日期
2020-12-24
DOI
10.1016/j.bcp.2020.114384
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T-cells
- (2020) Sandeep Artham et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- SLC39A7, regulated by miR-139-5p, induces cell proliferation, migration and inhibits apoptosis in gastric cancer via Akt/mTOR signaling pathway
- (2020) Yanting Zhang et al. BIOSCIENCE REPORTS
- RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs
- (2020) Sarah Bajan et al. Cells
- MicroRNAs (miRNAs) and Long Non-Coding RNAs (lncRNAs) as New Tools for Cancer Therapy: First Steps from Bench to Bedside
- (2020) Margherita Ratti et al. Targeted Oncology
- PAK1 inhibitor IPA-3 mitigates metastatic prostate cancer-induced bone remodeling
- (2020) Arti Verma et al. BIOCHEMICAL PHARMACOLOGY
- Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability
- (2019) Federico Teloni et al. MOLECULAR CELL
- Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires
- (2019) Xavier Bofill-De Ros et al. Cell Reports
- MiR-30a regulates cancer cell response to chemotherapy through SNAI1/IRS1/AKT pathway
- (2019) Tingting Wang et al. Cell Death & Disease
- PIK3CA in cancer: The past 30 years
- (2019) Rand Arafeh et al. SEMINARS IN CANCER BIOLOGY
- Curcumol inhibits colorectal cancer proliferation by targeting miR-21 and modulated PTEN/PI3K/Akt pathways
- (2019) Haowei Liu et al. LIFE SCIENCES
- Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy
- (2019) Shuang Qin et al. Journal of Hematology & Oncology
- A five-miRNA signature predicts survival in gastric cancer using bioinformatics analysis
- (2019) Ziqiang Zhang et al. GENE
- The Roles of MicroRNA in Lung Cancer
- (2019) Kuan-Li Wu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- PI3K isoforms in cell signalling and vesicle trafficking
- (2019) Benoit Bilanges et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Potential for microRNA Therapeutics and Clinical Research
- (2019) Johora Hanna et al. Frontiers in Genetics
- A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer
- (2019) Feifei Zhang et al. EBioMedicine
- PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway
- (2019) Xue Gao et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The unconventional role of Akt1 in the advanced cancers and in diabetes-promoted carcinogenesis
- (2019) Abdulrahman Alwhaibi et al. PHARMACOLOGICAL RESEARCH
- MiR-203a-3p regulates the biological behaviors of ovarian cancer cells through mediating the Akt/GSK-3β/Snail signaling pathway by targeting ATM
- (2019) Hong-Yun Liu et al. Journal of Ovarian Research
- miR‐107 regulates growth and metastasis of gastric cancer cells via activation of the PI3K‐AKT signaling pathway by down‐regulating FAT4
- (2019) Li Wang et al. Cancer Medicine
- Circulating MicroRNAs in Cancer: Potential and Challenge
- (2019) Mengying Cui et al. Frontiers in Genetics
- Elevated TRIP13 drives the AKT/mTOR pathway to induce the progression of hepatocellular carcinoma via interacting with ACTN4
- (2019) Meng-Xuan Zhu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies
- (2019) Khan et al. Cells
- Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis
- (2019) Abdulrahman Alwhaibi et al. BIOCHEMICAL PHARMACOLOGY
- The Regulatory Role of MicroRNAs in Breast Cancer
- (2019) Hui-Yi Loh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neuroprotection of miR-214 against isoflurane-induced neurotoxicity involves the PTEN/PI3K/Akt pathway in human neuroblastoma cell line SH-SY5Y
- (2019) Qiaoling Wu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- SOX9/miR-203a axis drives PI3K/AKT signaling to promote esophageal cancer progression
- (2019) Lianghai Wang et al. CANCER LETTERS
- Along the Central Dogma—Controlling Gene Expression with Small Molecules
- (2018) Tilman Schneider-Poetsch et al. Annual Review of Biochemistry
- MiR-502 mediates esophageal cancer cell TE1 proliferation by promoting AKT phosphorylation
- (2018) Jing Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-410–3p promotes prostate cancer progression via regulating PTEN/AKT/mTOR signaling pathway
- (2018) Yuelong Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer-associated fibroblasts in tumor microenvironment – Accomplices in tumor malignancy
- (2018) Zehuan Liao et al. CELLULAR IMMUNOLOGY
- MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway
- (2018) Chang Chai et al. CNS Neuroscience & Therapeutics
- MiR-564 is down-regulated in osteosarcoma and inhibits the proliferation of osteosarcoma cells via targeting Akt
- (2018) Neng Ru et al. GENE
- MicroRNA
- (2018) Thomas X. Lu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway
- (2018) Xiao Fu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop
- (2018) Feifei Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling
- (2018) Yubo Tang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Biomarkers for early identification of recurrences in HPV-driven oropharyngeal cancer
- (2018) Haitham Mirghani et al. ORAL ONCOLOGY
- MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway
- (2018) Dian-min Sun et al. Scientific Reports
- Coding and Non-coding RNAs, the Frontier Has Never Been So Blurred
- (2018) Florent Hubé et al. Frontiers in Genetics
- MiR-146b inhibits autophagy in prostate cancer by targeting the PTEN/Akt/mTOR signaling pathway
- (2018) Song Gao et al. Aging-US
- MiR-126-3p inhibits ovarian cancer proliferation and invasion via targeting PLXNB2
- (2018) Guixian Xiang et al. Reproductive Biology
- Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
- (2018) Jacob O'Brien et al. Frontiers in Endocrinology
- Cytokines in clinical cancer immunotherapy
- (2018) Pedro Berraondo et al. BRITISH JOURNAL OF CANCER
- Post-transcriptional control of miRNA biogenesis
- (2018) Gracjan Michlewski et al. RNA
- microRNAs Sculpt Neuronal Communication in a Tight Balance That Is Lost in Neurological Disease
- (2018) Kristen T. Thomas et al. Frontiers in Molecular Neuroscience
- miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer
- (2018) Yifeng Fang et al. Cancer Management and Research
- MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway
- (2017) Zhen Liang et al. Molecular Cancer
- The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer
- (2017) Martha L. Slattery et al. MOLECULAR CARCINOGENESIS
- Classical VEGF, Notch and Ang signalling in cancer angiogenesis, alternative approaches and future directions
- (2017) Nunzia Caporarello et al. Molecular Medicine Reports
- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing
- (2017) Li Jiang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Enhancing identification of cancer types via lowly-expressed microRNAs
- (2017) Roni Rasnic et al. NUCLEIC ACIDS RESEARCH
- Inhibition of miR-23a increases the sensitivity of lung cancer stem cells to erlotinib through PTEN/PI3K/Akt pathway
- (2017) Zhijun Han et al. ONCOLOGY REPORTS
- The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market
- (2017) Ricardo Titze-de-Almeida et al. PHARMACEUTICAL RESEARCH
- Focal photodynamic intracellular acidification as a cancer therapeutic
- (2017) Matthew J. Gdovin et al. SEMINARS IN CANCER BIOLOGY
- MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer
- (2017) Nana Li et al. Cell Death & Disease
- miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway
- (2017) Leilei Liang et al. Cell Death & Disease
- NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing
- (2017) Li Jiang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway
- (2017) Jinzhong Yu et al. MEDICAL SCIENCE MONITOR
- Cancer Screening and Early Detection in the 21 st Century
- (2017) Jennifer T. Loud et al. Seminars in Oncology Nursing
- miR-221/222 enhance the tumorigenicity of human breast cancer stem cells via modulation of PTEN/Akt pathway
- (2016) Bailong Li et al. BIOMEDICINE & PHARMACOTHERAPY
- Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination
- (2016) Jason S. L. Yu et al. DEVELOPMENT
- MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions
- (2016) Caterina Catalanotto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway
- (2016) JING HAN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Advances in cryoablation for pancreatic cancer
- (2016) Xiao-Mei Luo WORLD JOURNAL OF GASTROENTEROLOGY
- Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy
- (2016) Dong Geon Kim et al. Oncotarget
- Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells
- (2016) Ilaria Guerriero et al. Oncotarget
- CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo
- (2016) Hong Chang et al. Scientific Reports
- Global Cancer Incidence and Mortality Rates and Trends--An Update
- (2015) L. A. Torre et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Genetic deletion and pharmacological inhibition of Akt1 isoform attenuates bladder cancer cell proliferation, motility and invasion
- (2015) Harika Sabbineni et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- miR-15b/16-2 deletion promotes B-cell malignancies
- (2015) Francesca Lovat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer
- (2015) Wei-Dong Lu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway
- (2015) Yun-Li Chang et al. Oncotarget
- Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo
- (2015) Anna Goc et al. Oncotarget
- OncomiRDB: a database for the experimentally verified oncogenic and tumor-suppressive microRNAs
- (2014) Dongfang Wang et al. BIOINFORMATICS
- Early epigenetic cancer decisions
- (2014) Alberto Martín-Lorenzo et al. BIOLOGICAL CHEMISTRY
- Therapeutic Targeting of Cancers with Loss of PTEN Function
- (2014) Lloye Dillon et al. CURRENT DRUG TARGETS
- Deregulation of cell signaling in cancer
- (2014) Filippo G. Giancotti FEBS LETTERS
- miRNA-based therapies: strategies and delivery platforms for oligonucleotide and non-oligonucleotide agents
- (2014) Volker Baumann et al. Future Medicinal Chemistry
- Suppression of AKT expression by miR-153 produced anti-tumor activity in lung cancer
- (2014) Ye Yuan et al. INTERNATIONAL JOURNAL OF CANCER
- Gene Expression Correlation for Cancer Diagnosis: A Pilot Study
- (2014) Binbing Ling et al. Biomed Research International
- Overview: Cellular plasticity, cancer stem cells and metastasis
- (2013) Wael M. ElShamy et al. CANCER LETTERS
- Enrichment of ovarian cancer stem-like cells is associated with epithelial to mesenchymal transition through an miRNA-activated AKT pathway
- (2013) X. Luo et al. CELL PROLIFERATION
- Nanoparticle-mediated delivery of therapeutic genes: focus on miRNA therapeutics
- (2013) Muthunarayanan Muthiah et al. Expert Opinion on Drug Delivery
- Gastric Cancer
- (2013) Pelayo Correa GASTROENTEROLOGY CLINICS OF NORTH AMERICA
- MicroRNAs
- (2013) M. Bhaskaran et al. VETERINARY PATHOLOGY
- Noncoding RNAs in cancer and cancer stem cells
- (2013) Tianzhi Huang et al. Chinese Journal of Cancer
- Akt1 mediates prostate cancer cell microinvasion and chemotaxis to metastatic stimuli via integrin β3 affinity modulation
- (2012) A Goc et al. BRITISH JOURNAL OF CANCER
- MiR-93 enhances angiogenesis and metastasis by targeting LATS2
- (2012) Ling Fang et al. CELL CYCLE
- The Akt-associated microRNAs
- (2012) Min Xu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways
- (2012) S. Majid et al. CLINICAL CANCER RESEARCH
- Cancer and Radiation Therapy: Current Advances and Future Directions
- (2012) Rajamanickam Baskar et al. International Journal of Medical Sciences
- The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs
- (2011) Robert R. Langley et al. INTERNATIONAL JOURNAL OF CANCER
- First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
- (2011) Timothy A. Yap et al. JOURNAL OF CLINICAL ONCOLOGY
- AKT-ing via microRNA
- (2010) Danish Sayed et al. CELL CYCLE
- Vascular Endothelial Growth Factor as an Anti-Angiogenic Target for Cancer Therapy
- (2010) Gang Niu et al. CURRENT DRUG TARGETS
- PAK1 as a therapeutic target
- (2010) Julia V Kichina et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- MicroRNAs in Human Embryonic and Cancer Stem Cells
- (2010) Alfons Navarro et al. YONSEI MEDICAL JOURNAL
- A Brief Review on the Mechanisms of miRNA Regulation
- (2010) Yimei Cai et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Cancer Prevention: From 1727 to Milestones of the Past 100 Years
- (2009) Scott M. Lippman et al. CANCER RESEARCH
- Skeletal Disease Contributes Substantially to Morbidity and Mortality in Patients with Lung Cancer
- (2009) Vera Hirsh Clinical Lung Cancer
- The role of PAK-1 in activation of MAP kinase cascade and oncogenic transformation by Akt
- (2009) P R Somanath et al. ONCOGENE
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