miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

(2017) Yumeng Wang et al.   GENOME RESEARCH

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations

(2017) Anne Kosfeld et al.   HUMAN MOLECULAR GENETICS

Transforming growth factor-β1 regulation of ATF-3, c-Jun and JunB proteins for activation of matrix metalloproteinase-13 gene in human breast cancer cells

(2017) M. Gokulnath et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Hypermethylation of miRNA-589 promoter leads to upregulation of HDAC5 which promotes malignancy in non-small cell lung cancer

(2017) Changhong Liu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Diagnostic, Predictive, Prognostic, and Therapeutic Molecular Biomarkers in Third Millennium: A Breakthrough in Gastric Cancer

(2017) Nicola Carlomagno et al.   Biomed Research International

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer

(2016) Hanlin Zeng et al.   CANCER CELL

Circulating microRNAs as Potential Diagnostic Biomarkers and Therapeutic Targets in Gastric Cancer: Current Status and Future Perspectives

(2016) Hamed Mirzaei et al.   CURRENT MEDICINAL CHEMISTRY

Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling

(2016) Janina Wolf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-589-5p inhibits MAP3K8 and suppresses CD90+ cancer stem cells in hepatocellular carcinoma

(2016) Xi Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Gastric cancer

(2016) Eric Van Cutsem et al.   LANCET

miR-374a-CCND1-pPI3K/AKT-c-JUN feedback loop modulated by PDCD4 suppresses cell growth, metastasis and sensitizes nasopharyngeal carcinoma to cisplatin

(2016) Y Zhen et al.   ONCOGENE

Direct regulation of FOXK1 by C-jun promotes proliferation, invasion and metastasis in gastric cancer cells

(2016) Ying Peng et al.   Cell Death & Disease

LIFR functions as a metastasis suppressor in hepatocellular carcinoma by negatively regulating phosphoinositide 3-kinase/AKT pathway

(2015) Qin Luo et al.   CARCINOGENESIS

The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review)

(2015) HUA-FU ZHAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A novel long noncoding RNA-LOWEG is low expressed in gastric cancer and acts as a tumor suppressor by inhibiting cell invasion

(2015) Jun-hua Zhao et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Update on Metastatic Gastric and Esophageal Cancers

(2015) Manish A. Shah   JOURNAL OF CLINICAL ONCOLOGY

COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis

(2015) Jing Shao et al.   NEOPLASIA

Deregulated microRNAs in gastric cancer tissue-derived mesenchymal stem cells: novel biomarkers and a mechanism for gastric cancer

(2014) M Wang et al.   BRITISH JOURNAL OF CANCER

miR200c Attenuates P-gp-Mediated MDR and Metastasis by Targeting JNK2/c-Jun Signaling Pathway in Colorectal Cancer

(2014) H. Sui et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Gastric juice MicroRNAs as potential biomarkers for the screening of gastric cancer

(2013) Long Cui et al.   CANCER

MicroRNAs as novel biological targets for detection and regulation

(2013) Jinbo Li et al.   CHEMICAL SOCIETY REVIEWS

c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs

(2013) M. Gustems et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs in Pathogenesis, Diagnosis, and Treatment of Gastroesophageal Cancers

(2012) Jee Hoon Song et al.   GASTROENTEROLOGY

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

(2012) Dahu Chen et al.   NATURE MEDICINE

Treatment strategy for early gastric cancer

(2011) J. Wang et al.   SURGICAL ONCOLOGY-OXFORD

The interplay between transcription factors and microRNAs in genome-scale regulatory networks

(2009) Natalia J. Martinez et al.   BIOESSAYS

Leukemia inhibitory factor receptor (LIFR) is detected as a novel suppressor gene of hepatocellular carcinoma using double-combination array

(2009) Yukiyasu Okamura et al.   CANCER LETTERS

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE