New insights into the interplay between miRNAs and autophagy in the aging of intervertebral discs
出版年份 2020 全文链接
标题
New insights into the interplay between miRNAs and autophagy in the aging of intervertebral discs
作者
关键词
Ageing, Intervertebral disc, miRNA, Autophagy
出版物
AGEING RESEARCH REVIEWS
Volume 65, Issue -, Pages 101227
出版商
Elsevier BV
发表日期
2020-11-22
DOI
10.1016/j.arr.2020.101227
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Suppression of miR-203-3p inhibits lipopolysaccharide induced human intervertebral disc inflammation and degeneration through upregulating estrogen receptor α
- (2020) Zhongxu Cai et al. GENE THERAPY
- miR-24-3p induces human intervertebral disc degeneration by targeting insulin-like growth factor binding protein 5 and the ERK signaling pathway
- (2020) Zhonghui Chen et al. LIFE SCIENCES
- Overexpression of microRNA-185 alleviates intervertebral disc degeneration through inactivation of the Wnt/β-catenin signaling pathway and downregulation of Galectin-3
- (2020) Zhennan Yun et al. Molecular Pain
- MicroRNAs as major regulators of the autophagy pathway
- (2020) Yunus Akkoc et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- MicroRNA-129-5p affects immune privilege and apoptosis of nucleus pulposus cells via regulating FADD in intervertebral disc degeneration
- (2020) Nan Li et al. CELL CYCLE
- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- Rapamycin Induced Autophagy Inhibits Inflammation-Mediated Endplate Degeneration by Enhancing Nrf2/Keap1 Signaling of Cartilage Endplate Stem Cells
- (2019) Rui Zuo et al. STEM CELLS
- Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction
- (2019) Y. Kakiuchi et al. OSTEOARTHRITIS AND CARTILAGE
- MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells
- (2019) Jie Zhou et al. LIFE SCIENCES
- Role of Epigenomics in Bone and Cartilage Disease
- (2019) Joyce BJ van Meurs et al. JOURNAL OF BONE AND MINERAL RESEARCH
- miR-573 regulates cell proliferation and apoptosis by targeting Bax in nucleus pulposus cells
- (2019) Rui Wang et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- MiR-499a-5p suppresses apoptosis of human nucleus pulposus cells and degradation of their extracellular matrix by targeting SOX4
- (2019) Jing-chuan Sun et al. BIOMEDICINE & PHARMACOTHERAPY
- MicroRNA-206 inhibition and activation of the AMPK/Nampt signaling pathway enhance sevoflurane postconditioning-induced amelioration of myocardial ischemia/reperfusion injury
- (2019) Tao Li et al. JOURNAL OF DRUG TARGETING
- Mechanical Function of the Nucleus Pulposus of the Intervertebral Disc Under High Rates of Loading
- (2019) Nicolas Newell et al. SPINE
- miR-21-5p protects IL-1β-induced human chondrocytes from degradation
- (2019) Hai Zhu et al. Journal of Orthopaedic Surgery and Research
- Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells
- (2019) Weiwei Yi et al. Aging-US
- MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling
- (2019) Chen Cai et al. Aging-US
- Ammonia inhalation-mediated mir-202-5p leads to cardiac autophagy through PTEN/AKT/mTOR pathway
- (2019) Houjuan Xing et al. CHEMOSPHERE
- Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen
- (2019) Sidong Yang et al. AGEING RESEARCH REVIEWS
- Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health
- (2019) Elizabeth S Silagi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- MiR-21 promotes ECM degradation through inhibiting autophagy via the PTEN/akt/mTOR signaling pathway in human degenerated NP cells
- (2018) Wen-Jun Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Inhibition of miR-20 promotes proliferation and autophagy in articular chondrocytes by PI3K/AKT/mTOR signaling pathway
- (2018) Weidong He et al. BIOMEDICINE & PHARMACOTHERAPY
- MicroRNA-155 suppresses the catabolic effect induced by TNF-α and IL-1β by targeting C/EBPβ in rat nucleus pulposus cells
- (2018) Jie Zhou et al. CONNECTIVE TISSUE RESEARCH
- Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration
- (2018) Zengming Zheng et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- High Glucose Induces Autophagy through PPARγ-Dependent Pathway in Human Nucleus Pulposus Cells
- (2018) Chang Jiang et al. PPAR Research
- Inhibition of microRNA-30d attenuates the apoptosis and extracellular matrix degradation of degenerative human nucleus pulposus cells by up-regulating SOX9
- (2018) Junlin Lv et al. CHEMICO-BIOLOGICAL INTERACTIONS
- TGF-β/SMAD signaling inhibits intermittent cyclic mechanical tension-induced degeneration of endplate chondrocytes by regulating the miR-455-5p/RUNX2 axis
- (2018) Liang Xiao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- microRNA-206 is required for osteoarthritis development through its effect on apoptosis and autophagy of articular chondrocytes via modulating the phosphoinositide 3-kinase/protein kinase B-mTOR pathway by targeting insulin-like growth factor-1
- (2018) Qian Yu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- LINC00641 regulates autophagy and intervertebral disc degeneration by acting as a competitive endogenous RNA of miR-153-3p under nutrition deprivation stress
- (2018) Xiao-Bo Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Preclinical development of a microRNA-based therapy for intervertebral disc degeneration
- (2018) Ming-liang Ji et al. Nature Communications
- A new function for miRNAs as regulators of autophagy
- (2017) Francesca Aredia et al. Future Medicinal Chemistry
- Mechanism of microRNA-21 regulating IL-6 inflammatory response and cell autophagy in intervertebral disc degeneration
- (2017) Hao Lin et al. Experimental and Therapeutic Medicine
- Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration
- (2017) Kangcheng Zhao et al. Oncotarget
- The PI3K/Akt pathway: a critical player in intervertebral disc degeneration
- (2017) Zhi-Hua Ouyang et al. Oncotarget
- The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway
- (2017) Pei Li et al. Scientific Reports
- Tumor necrosis factor-α: a key contributor to intervertebral disc degeneration
- (2016) Cheng Wang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- MicroRNA-7 regulates IL-1β-induced extracellular matrix degeneration by targeting GDF5 in human nucleus pulposus cells
- (2016) Wei Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
- (2016) Chencheng Feng et al. CELL CYCLE
- F-actin rearrangement is regulated by mTORC2/Akt/Girdin in mouse fertilized eggs
- (2016) Didi Wu et al. CELL PROLIFERATION
- MicroRNA-129 in Human Cancers: from Tumorigenesis to Clinical Treatment
- (2016) Yanping Gao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Resveratrol attenuated TNF-α–induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway
- (2016) Xiao-Hu Wang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Mammalian target of rapamycin (mTOR) complex 2 regulates filamin A-dependent focal adhesion dynamics and cell migration
- (2016) Tatsuhiro Sato et al. GENES TO CELLS
- MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions
- (2016) Caterina Catalanotto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MicroRNA-21 protects against cardiac hypoxia/reoxygenation injury by inhibiting excessive autophagy in H9c2 cellsviathe Akt/mTOR pathway
- (2016) Zhouqing Huang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Molecular mechanisms of biological aging in intervertebral discs
- (2016) Nam V. Vo et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Distribution of miRNA expression across human tissues
- (2016) Nicole Ludwig et al. NUCLEIC ACIDS RESEARCH
- Matrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression
- (2016) Ming-Han Liu et al. Scientific Reports
- Hypoxia facilitates the survival of nucleus pulposus cells in serum deprivation by down-regulating excessive autophagy through restricting ROS generation
- (2015) Jiang-Wei Chen et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition
- (2015) KANG XU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Dysregulated miR-98 Contributes to Extracellular Matrix Degradation by Targeting IL-6/STAT3 Signaling Pathway in Human Intervertebral Disc Degeneration
- (2015) Ming-liang Ji et al. JOURNAL OF BONE AND MINERAL RESEARCH
- MiR-34a promotes Fas-mediated cartilage endplate chondrocyte apoptosis by targeting Bcl-2
- (2015) Huajiang Chen et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Mechanics and biology in intervertebral disc degeneration: a vicious circle
- (2015) P.-P.A. Vergroesen et al. OSTEOARTHRITIS AND CARTILAGE
- Autophagy in the Degenerating Human Intervertebral Disc
- (2015) Helen E. Gruber et al. SPINE
- Disc degeneration implies low back pain
- (2015) Chang-Jiang Zheng et al. Theoretical Biology and Medical Modelling
- Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells
- (2015) Shingo Miyazaki et al. ARTHRITIS RESEARCH & THERAPY
- MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway
- (2015) Changjun He et al. Oncotarget
- IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc
- (2015) Zhongyi Sun et al. Journal of Orthopaedic Surgery and Research
- Identification of miR-194-5p as a potential biomarker for postmenopausal osteoporosis
- (2015) Jia Meng et al. PeerJ
- Autophagy protects end plate chondrocytes from intermittent cyclic mechanical tension induced calcification
- (2014) Hong-guang Xu et al. BONE
- Glucosamine protects nucleus pulposus cells and induces autophagy via the mTOR-dependent pathway
- (2014) LiBo Jiang et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- mTOR and autophagy: A dynamic relationship governed by nutrients and energy
- (2014) E.A. Dunlop et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Deconvoluting the role of reactive oxygen species and autophagy in human diseases
- (2013) Xin Wen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Characterization of microRNA expression profiles in patients with intervertebral disc degeneration
- (2013) BO ZHAO et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells
- (2013) Eun-Young Park et al. INTERNATIONAL ORTHOPAEDICS
- Lactate down-regulates matrix systhesis and promotes apoptosis and autophagy in rat nucleus pulposus cells
- (2013) Wei Wu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Intervertebral disc regeneration: from the degenerative cascade to molecular therapy and tissue engineering
- (2013) Gianluca Vadalà et al. Journal of Tissue Engineering and Regenerative Medicine
- Role of cytokines in intervertebral disc degeneration: pain and disc content
- (2013) Makarand V. Risbud et al. Nature Reviews Rheumatology
- Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression
- (2013) K.-G. Ma et al. OSTEOARTHRITIS AND CARTILAGE
- MicroRNA-10b Promotes Nucleus Pulposus Cell Proliferation through RhoC-Akt Pathway by Targeting HOXD10 in Intervetebral Disc Degeneration
- (2013) Xin Yu et al. PLoS One
- The evidence and the possible significance of autophagy in degeneration model of human cervical end-plate cartilage
- (2013) HONGGUANG XU et al. Experimental and Therapeutic Medicine
- Effects of TGF-β1 and IL-1β on expression of ADAMTS enzymes and TIMP-3 in human intervertebral disc degeneration
- (2013) SHI-LONG WANG et al. Experimental and Therapeutic Medicine
- Role of mitochondrial pathway in compression-induced apoptosis of nucleus pulposus cells
- (2012) Fan Ding et al. APOPTOSIS
- AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization
- (2012) Hildegard I.D. Mack et al. Autophagy
- Increased Macroautophagy in the Pathological Process of Intervertebral Disc Degeneration in Rats
- (2012) Wei Ye et al. CONNECTIVE TISSUE RESEARCH
- Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3
- (2011) Hai-Qiang Wang et al. JOURNAL OF PATHOLOGY
- Autophagy in rat annulus fibrosus cells: evidence and possible implications
- (2011) Chao Shen et al. ARTHRITIS RESEARCH & THERAPY
- Degeneration and regeneration of the intervertebral disc: lessons from development
- (2010) L. J. Smith et al. Disease Models & Mechanisms
- Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro
- (2010) M. M. Abouheif et al. RHEUMATOLOGY
- The Rising Prevalence of Chronic Low Back Pain
- (2009) Janet K. Freburger et al. ARCHIVES OF INTERNAL MEDICINE
- RISC-target interaction: Cleavage and translational suppression
- (2008) A VANDENBERG et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
- (2008) Witold Filipowicz et al. NATURE REVIEWS GENETICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started