4.5 Review

A new function for miRNAs as regulators of autophagy

期刊

FUTURE MEDICINAL CHEMISTRY
卷 9, 期 1, 页码 25-36

出版社

Newlands Press Ltd
DOI: 10.4155/fmc-2016-0173

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antagomir; autophagy; biomarker; cancer; miRNA; oncomiR; tumor suppressor miRNA

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Autophagy is a self-digestive process regulated by an intricate network of factors able either to ensure the prosurvival function of autophagy or to convert it in a death pathway. Recently, the involvement of miRNAs in the regulation of autophagy networks has been reported. This review will summarize the main features of these small noncoding endogenous RNAs, focusing on their relevance in cancer and finally addressing their impact on autophagy.

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