期刊
FUTURE MEDICINAL CHEMISTRY
卷 9, 期 1, 页码 25-36出版社
Newlands Press Ltd
DOI: 10.4155/fmc-2016-0173
关键词
antagomir; autophagy; biomarker; cancer; miRNA; oncomiR; tumor suppressor miRNA
Autophagy is a self-digestive process regulated by an intricate network of factors able either to ensure the prosurvival function of autophagy or to convert it in a death pathway. Recently, the involvement of miRNAs in the regulation of autophagy networks has been reported. This review will summarize the main features of these small noncoding endogenous RNAs, focusing on their relevance in cancer and finally addressing their impact on autophagy.
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