标题
Tumor necrosis factor-α: a key contributor to intervertebral disc degeneration
作者
关键词
-
出版物
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
Volume 49, Issue 1, Pages 1-13
出版商
Oxford University Press (OUP)
发表日期
2016-10-16
DOI
10.1093/abbs/gmw112
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human bone morphogenetic protein 7 transfected nucleus pulposus cells delay the degeneration of intervertebral disc in dogs
- (2017) Tao Gu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- CCAAT/enhancer binding protein β regulates the expression of tumor necrosis factor-α in the nucleus pulposus cells
- (2016) Akihiko Hiyama et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Acute and Chronic Low Back Pain
- (2016) Nathan Patrick et al. MEDICAL CLINICS OF NORTH AMERICA
- Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration
- (2016) Stephen M. Richardson et al. METHODS
- Elevated levels of tumor necrosis factor-α and TNFR1 in recurrent herniated lumbar discs correlate with chronicity of postoperative sciatic pain
- (2016) Pablo Andrade et al. Spine Journal
- Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo
- (2016) Alon Lai et al. Spine Journal
- Delivery systems for the treatment of degenerated intervertebral discs
- (2015) S.B.G. Blanquer et al. ADVANCED DRUG DELIVERY REVIEWS
- TNFα triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNFα responses of the parental cells
- (2015) Miwa Sohda et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The Effects of Platelet-Rich Plasma on Halting the Progression in Porcine Intervertebral Disc Degeneration
- (2015) Hongsik Cho et al. ARTIFICIAL ORGANS
- MicroRNA-494 inhibition protects nucleus pulposus cells from TNF-α-induced apoptosis by targeting JunD
- (2015) Tao Wang et al. BIOCHIMIE
- Fulgidic Acid Isolated from the Rhizomes of Cyperus rotundus Suppresses LPS-Induced iNOS, COX-2, TNF-α, and IL-6 Expression by AP-1 Inactivation in RAW264.7 Macrophages
- (2015) Ji-Sun Shin et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence
- (2015) Ruo-Feng Yin et al. CHINESE MEDICAL JOURNAL
- Interleukin-1β in intervertebral disk degeneration
- (2015) Wei Yang et al. CLINICA CHIMICA ACTA
- MMPs and ADAMTSs in intervertebral disc degeneration
- (2015) Wen-Jun Wang et al. CLINICA CHIMICA ACTA
- TGF-β1 antagonizes TNF-αinduced up-regulation of matrix metalloproteinase 3 in nucleus pulposus cells: role of the ERK1/2 pathway
- (2015) Hao Yang et al. CONNECTIVE TISSUE RESEARCH
- Symptomatic versus Asymptomatic Intervertebral Disc Degeneration: Is Inflammation the Key?
- (2015) Yan Peng et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Intervertebral disc degenerative changes after intradiscal injection of TNF-α in a porcine model
- (2015) Ran Kang et al. EUROPEAN SPINE JOURNAL
- Proinflammatory cytokines modulate the chemokine CCL2 (MCP-1) in human annulus cells in vitro: CCL2 expression and production
- (2015) Helen E. Gruber et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells
- (2015) Mei-Xia Wang et al. EXPERIMENTAL NEUROLOGY
- Gallic Acid-g-Chitosan Modulates Inflammatory Responses in LPS-Stimulated RAW264.7 Cells Via NF-κB, AP-1, and MAPK Pathways
- (2015) Chang-Bum Ahn et al. INFLAMMATION
- Adipose-Derived Stromal Cells Protect Intervertebral Disc Cells in Compression: Implications for Stem Cell Regenerative Disc Therapy
- (2015) Zhen Sun et al. International Journal of Biological Sciences
- The Function of Autophagy in Neurodegenerative Diseases
- (2015) Yoshimitsu Kiriyama et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Growth factors and platelet-rich plasma: promising biological strategies for early intervertebral disc degeneration
- (2015) Shan-zheng Wang et al. INTERNATIONAL ORTHOPAEDICS
- Prolyl-4-hydroxylase Domain Protein 2 Controls NF-κB/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on Cells of the Nucleus Pulposus
- (2015) Jun Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatocyte growth factor/c-met promotes proliferation, suppresses apoptosis, and improves matrix metabolism in rabbit nucleus pulposus cells in vitro
- (2015) Hidenobu Ishibashi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Inflammation in intervertebral disc degeneration and regeneration
- (2015) M. Molinos et al. Journal of the Royal Society Interface
- Autophagy prevents age-related OA
- (2015) João H. Duarte Nature Reviews Rheumatology
- Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes
- (2015) K.L.E. Phillips et al. OSTEOARTHRITIS AND CARTILAGE
- Mechanics and biology in intervertebral disc degeneration: a vicious circle
- (2015) P.-P.A. Vergroesen et al. OSTEOARTHRITIS AND CARTILAGE
- Low Level Light Therapy Modulates Inflammatory Mediators Secreted by Human Annulus Fibrosus Cells during Intervertebral Disc DegenerationIn Vitro
- (2015) Min Ho Hwang et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Autophagy in the Degenerating Human Intervertebral Disc
- (2015) Helen E. Gruber et al. SPINE
- Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells
- (2015) Benjamin A. Walter et al. SPINE
- Mitochondrial Membrane Potential and Nuclear and Gene Expression Changes During Human Disc Cell Apoptosis
- (2015) Helen E. Gruber et al. SPINE
- Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug
- (2015) Morakot Likhitpanichkul et al. Spine Journal
- TNFRs and Control of Chronic LCMV Infection: Implications for Therapy
- (2015) Derek L. Clouthier et al. TRENDS IN IMMUNOLOGY
- Repeated Exposure to High-Frequency Low-Amplitude Vibration Induces Degeneration of Murine Intervertebral Discs and Knee Joints
- (2015) Matthew R. McCann et al. Arthritis & Rheumatology
- Brazilian Red Propolis Attenuates Inflammatory Signaling Cascade in LPS-Activated Macrophages
- (2015) Bruno Bueno-Silva et al. PLoS One
- Tumor Necrosis Factor-α– and Interleukin-1β–Dependent Matrix Metalloproteinase-3 Expression in Nucleus Pulposus Cells Requires Cooperative Signaling via Syndecan 4 and Mitogen-Activated Protein Kinase–NF-κB Axis
- (2014) Xin Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- Structural basis of cell apoptosis and necrosis in TNFR signaling
- (2014) Jing Huang et al. APOPTOSIS
- Autophagy protects end plate chondrocytes from intermittent cyclic mechanical tension induced calcification
- (2014) Hong-guang Xu et al. BONE
- Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients
- (2014) Haidong Xu et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Cell and molecular biology of intervertebral disc degeneration: current understanding and implications for potential therapeutic strategies
- (2014) SZ. Wang et al. CELL PROLIFERATION
- The Responses of Autophagy and Apoptosis to Oxidative Stress in Nucleus Pulposus Cells: Implications for Disc Degeneration
- (2014) Jiang-Wei Chen et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Molecular Basis of Intervertebral Disc Degeneration and Herniations: What Are the Important Translational Questions?
- (2014) Tiffany Kadow et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- Steroid treatment can inhibit nuclear localization of members of the NF-κB pathway in human disc cells stimulated with TNF-α
- (2014) Meiling Quan et al. European Journal of Orthopaedic Surgery and Traumatology
- Persistent degenerative changes in the intervertebral disc after burst fracture in an in vitro model mimicking physiological post-traumatic conditions
- (2014) Stefan Dudli et al. EUROPEAN SPINE JOURNAL
- Expression and regulation of toll-like receptors (TLRs) in human intervertebral disc cells
- (2014) Marina Klawitter et al. EUROPEAN SPINE JOURNAL
- Production and expression of RANTES (CCL5) by human disc cells and modulation by IL-1-β and TNF-α in 3D culture
- (2014) Helen E. Gruber et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Tumor necrosis factor alpha promotes the proliferation of human nucleus pulposus cells via nuclear factor-κB, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase
- (2014) Xiao-Hu Wang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- A Genotoxic Stress-Responsive miRNA, miR-574-3p, Delays Cell Growth by Suppressing the Enhancer of Rudimentary Homolog Gene in Vitro
- (2014) Ken-ichi Ishikawa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Blocking the Function of Inflammatory Cytokines and Mediators by Using IL-10 and TGF-β: A Potential Biological Immunotherapy for Intervertebral Disc Degeneration in a Beagle Model
- (2014) Wei Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Glucosamine protects nucleus pulposus cells and induces autophagy via the mTOR-dependent pathway
- (2014) LiBo Jiang et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- The catabolic effect of TNFα on bovine nucleus pulposus intervertebral disc cells and the restraining role of glucosamine sulfate in the TNFα-mediated up-regulation of MMP-3
- (2014) Eleni Mavrogonatou et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- LIM mineralization protein-1 suppresses TNF-α induced intervertebral disc degeneration by maintaining nucleus pulposus extracellular matrix production and inhibiting matrix metalloproteinases expression
- (2014) Hui Liu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Unknown
- (2014) Elias Vasiliadis et al. MOLECULAR MEDICINE
- Inhibiting IκB Kinase-β Downregulates Inflammatory Cytokines in Injured Discs and Neuropeptides in Dorsal Root Ganglia Innervating Injured Discs in Rats
- (2014) Sayako Kobori et al. SPINE
- The anabolic effect of plasma-mediated ablation on the intervertebral disc: stimulation of proteoglycan and interleukin-8 production
- (2014) Fabrice A. Kuelling et al. Spine Journal
- Histone Deacetylase Inhibitor Impairs Plasminogen Activator Inhibitor-1 Expression via Inhibiting TNF-α-Activated MAPK/AP-1 Signaling Cascade
- (2014) Wei-Lin Chen et al. Biomed Research International
- Inflammatory Cytokines Associated with Degenerative Disc Disease Control Aggrecanase-1 (ADAMTS-4) Expression in Nucleus Pulposus Cells through MAPK and NF-κB
- (2013) Ye Tian et al. AMERICAN JOURNAL OF PATHOLOGY
- Epidural Steroids, Etanercept, or Saline in Subacute Sciatica
- (2013) Steven P. Cohen ANNALS OF INTERNAL MEDICINE
- Cell death in intervertebral disc degeneration
- (2013) Fan Ding et al. APOPTOSIS
- Death domain complex of the TNFR-1, TRADD, and RIP1 proteins for death-inducing signaling
- (2013) Young-Hoon Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Increased IL-17 expression in degenerated human discs and increased production in cultured annulus cells exposed to IL-1ß and TNF-α
- (2013) HE Gruber et al. BIOTECHNIC & HISTOCHEMISTRY
- Synergistic Effect of Combined Growth Factors in Porcine Intervertebral Disc Degeneration
- (2013) Hongsik Cho et al. CONNECTIVE TISSUE RESEARCH
- Autoimmunity in intervertebral disc herniation: from bench to bedside
- (2013) Alberto Di Martino et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Regulation of Huntingtin Gene Expression by miRNA-137, -214, -148a, and Their Respective isomiRs
- (2013) Emilia Kozlowska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells
- (2013) Hua Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Processes of Sterile Inflammation
- (2013) H. Shen et al. JOURNAL OF IMMUNOLOGY
- Anti-inflammatory effect of platelet-rich plasma on nucleus pulposus cells with response of TNF-α and IL-1
- (2013) Ho-Joong Kim et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Leptin Induces Cyclin D1 Expression and Proliferation of Human Nucleus Pulposus Cells via JAK/STAT, PI3K/Akt and MEK/ERK Pathways
- (2013) Zheng Li et al. PLoS One
- TNF-α Induces Cytosolic Phospholipase A2 Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation
- (2013) I-Ta Lee et al. PLoS One
- TNF-α and its receptors modulate complex behaviours and neurotrophins in transgenic mice
- (2013) Marie Lou Camara et al. PSYCHONEUROENDOCRINOLOGY
- Tumor Necrosis Factor-α-Dependent Infiltration of Macrophages Into the Dorsal Root Ganglion in a Rat Disc Herniation Model
- (2013) Changcheng You et al. SPINE
- Substance P Stimulates Production of Inflammatory Cytokines in Human Disc Cells
- (2013) Christopher K. Kepler et al. SPINE
- Randomized, Double-blind, Placebo-Controlled, Trial of Transforaminal Epidural Etanercept for the Treatment of Symptomatic Lumbar Disc Herniation
- (2013) Brian J. C. Freeman et al. SPINE
- Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration
- (2013) Nam V. Vo et al. Spine Journal
- The molecular basis of intervertebral disc degeneration
- (2013) Christopher K. Kepler et al. Spine Journal
- Bone morphogenetic protein-7 antagonizes tumor necrosis factor-α–induced activation of nuclear factor κB and up-regulation of the ADAMTS, leading to decreased degradation of disc matrix macromolecules aggrecan and collagen II
- (2013) Zili Wang et al. Spine Journal
- Autophagy regulates TNFα-mediated joint destruction in experimental arthritis
- (2012) Neng-Yu Lin et al. ANNALS OF THE RHEUMATIC DISEASES
- Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
- (2012) Jianru Wang et al. ARTHRITIS AND RHEUMATISM
- The role of TRADD in death receptor signaling
- (2012) Yelena L. Pobezinskaya et al. CELL CYCLE
- Increased Macroautophagy in the Pathological Process of Intervertebral Disc Degeneration in Rats
- (2012) Wei Ye et al. CONNECTIVE TISSUE RESEARCH
- Tumor Necrosis Factor-α Signaling in Macrophages
- (2012) Narayanan Parameswaran et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Efficacy of epidural administration of anti-interleukin-6 receptor antibody onto spinal nerve for treatment of sciatica
- (2012) Seiji Ohtori et al. EUROPEAN SPINE JOURNAL
- Prolyl Hydroxylase 3 (PHD3) Modulates Catabolic Effects of Tumor Necrosis Factor-α (TNF-α) on Cells of the Nucleus Pulposus through Co-activation of Nuclear Factor κB (NF-κB)/p65 Signaling
- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhancing human nucleus pulposus cells for biological treatment approaches of degenerative intervertebral disc diseases: a systematic review
- (2012) Demissew Shenegelegn Mern et al. Journal of Tissue Engineering and Regenerative Medicine
- Tumor Necrosis Factor-α-Immunoreactive Cells in Nucleus Pulposus in Adolescent Patients With Lumbar Disc Herniation
- (2012) Seiji Ohtori et al. SPINE
- Toll-Like Receptor 4 (TLR4) Expression and Stimulation in a Model of Intervertebral Disc Inflammation and Degeneration
- (2012) Neena E. Rajan et al. SPINE
- Adalimumab in acute sciatica reduces the long-term need for surgery: a 3-year follow-up of a randomised double-blind placebo-controlled trial
- (2011) S Genevay et al. ANNALS OF THE RHEUMATIC DISEASES
- Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: Implications in degenerative disc disease
- (2011) Akihiko Hiyama et al. ARTHRITIS AND RHEUMATISM
- Specific inhibitory protein Dkk-1 blocking Wnt/β-catenin signaling pathway improve protectives effect on the extracellular matrix
- (2011) Shunan Ye et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways
- (2011) Harris Pratsinis et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- TNFα-Induced Necroptosis and Autophagy via Supression of the p38–NF-κB Survival Pathway in L929 Cells
- (2011) Yuan-Chao Ye et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Expression of ADAMTS-7 and ADAMTS-12 in the Nucleus Pulposus During Degeneration of Rat Caudal Intervetebral Disc
- (2011) Hao YU et al. JOURNAL OF VETERINARY MEDICAL SCIENCE
- Tumor necrosis factor-α levels correlate with postoperative pain severity in lumbar disc hernia patients: Opposite clinical effects between tumor necrosis factor receptor 1 and 2
- (2011) Pablo Andrade et al. PAIN
- Attenuation of Inflammatory Events in Human Intervertebral Disc Cells With a Tumor Necrosis Factor Antagonist
- (2011) S. Michael Sinclair et al. SPINE
- Epidural Administration of Spinal Nerves With the Tumor Necrosis Factor-Alpha Inhibitor, Etanercept, Compared With Dexamethasone for Treatment of Sciatica in Patients With Lumbar Spinal Stenosis
- (2011) Seiji Ohtori et al. SPINE
- Annulus Fibrosus Cells Interact With Neuron-Like Cells to Modulate Production of Growth Factors and Cytokines in Symptomatic Disc Degeneration
- (2011) Hong Joo Moon et al. SPINE
- Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells
- (2010) Jae-Sung Kim et al. ARTHRITIS AND RHEUMATISM
- Adalimumab in severe and acute sciatica: A multicenter, randomized, double-blind, placebo-controlled trial
- (2010) Stéphane Genevay et al. ARTHRITIS AND RHEUMATISM
- Nitric oxide and calcium signaling regulate myocardial tumor necrosis factor-α expression and cardiac function in sepsisThis article is one of a selection of papers published in this special issue on Calcium Signaling.
- (2010) Ting Zhang et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Histone Deacetylase-3 Activation Promotes Tumor Necrosis Factor-α (TNF-α) Expression in Cardiomyocytes during Lipopolysaccharide Stimulation
- (2010) Huaqing Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Experimental study on inhibitory effect of niacinamide on tumor necrosis factor-alpha-induced matrix degradation of annulus fibrous tissue in vitro
- (2010) Runbing Xu et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells
- (2010) Mostafa A. Gabr et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Randomized, Double-blind, Placebo-controlled, Dose-response, and Preclinical Safety Study of Transforaminal Epidural Etanercept for the Treatment of Sciatica
- (2009) Steven P. Cohen et al. ANESTHESIOLOGY
- Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation
- (2009) Stéphane Genevay et al. ARTHRITIS RESEARCH & THERAPY
- Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
- (2009) S Jane Millward-Sadler et al. ARTHRITIS RESEARCH & THERAPY
- Lumbar Intervertebral Disk Degeneration in Athletes
- (2008) Mika Hangai et al. AMERICAN JOURNAL OF SPORTS MEDICINE
- Pathophysiology of the human intervertebral disc
- (2008) Alessandra Colombini et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
- (2008) Melissa K McCoy et al. Journal of Neuroinflammation
- Role of the tumor necrosis factor-α, cyclooxygenase-2, prostaglandin E2, and effect of low-intensity pulsed ultrasound in an in vitro herniated disc resorption model
- (2008) Sadahiro Iwabuchi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Higher Risk of Adjacent Segment Degeneration After Floating Fusions: Long-Term Outcome After Low Lumbar Spine Fusions
- (2008) Alexander Carl Disch et al. JOURNAL OF SPINAL DISORDERS & TECHNIQUES
- Widespread changes in protein synthesis induced by microRNAs
- (2008) Matthias Selbach et al. NATURE
- Human Tumour Necrosis Factor: Physiological and Pathological Roles in Placenta and Endometrium
- (2008) S. Haider et al. PLACENTA
- Bone morphogenetic protein-7 protects human intervertebral disc cells in vitro from apoptosis
- (2007) Aiqun Wei et al. Spine Journal
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started