Environmentally induced epigenetic toxicity: potential public health concerns

Vinclozolin Treatment Induces Reproductive Malformations and Infertility in Male Rats When Administered During Sexual but Not Gonadal Differentiation; However, the Effects Are Not Transmitted to the Subsequent Generations.

(2017) Leon Earl Gray et al.   BIOLOGY OF REPRODUCTION

Long noncoding RNAs: Lessons from genomic imprinting

(2016) Chandrasekhar Kanduri   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution

(2016) Hari K. Somineni et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MicroRNA changes, activation of progenitor cells and severity of liver injury in mice induced by choline and folate deficiency

(2016) Volodymyr P. Tryndyak et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A twist in zygotic reprogramming

(2016) Daniel M. Messerschmidt   NATURE CELL BIOLOGY

MicroRNA and Embryo Implantation

(2015) Weimin Liu et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Alcohol-induced histone H3K9 hyperacetylation and cardiac hypertrophy are reversed by a histone acetylases inhibitor anacardic acid in developing murine hearts

(2015) Chang Peng et al.   BIOCHIMIE

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

(2015) Walfred W.C. Tang et al.   CELL

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes

(2015) Peng Zhang et al.   CELL RESEARCH

X-chromosome inactivation: new insights into cis and trans regulation

(2015) Rafael Galupa et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development

(2015) Shuiqiao Yuan et al.   DEVELOPMENT

Bisphenol A Exposure Disrupts Metabolic Health Across Multiple Generations in the Mouse

(2015) Martha Susiarjo et al.   ENDOCRINOLOGY

A review on endocrine disruptors and their possible impacts on human health

(2015) Eva Rahman Kabir et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Identification of SecretaglobinScgb2a1as a target for developmental reprogramming by BPA in the rat prostate

(2015) Rebecca Lee Yean Wong et al.   Epigenetics

Long-term effects of radiation exposure on health

(2015) Kenji Kamiya et al.   LANCET

Spatiotemporal-specific lncRNAs in the brain, colon, liver and lung of macaque during development

(2015) Feng Li et al.   Molecular BioSystems

Long non-coding RNA regulation of reproduction and development

(2015) David H. Taylor et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Age-related formaldehyde interferes with DNA methyltransferase function, causing memory loss in Alzheimer's disease

(2015) Zhiqian Tong et al.   NEUROBIOLOGY OF AGING

Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet

(2015) Ethika Tyagi et al.   NEUROBIOLOGY OF DISEASE

Long-term supplementation with a low dose of proanthocyanidins normalized liver miR-33a and miR-122 levels in high-fat diet–induced obese rats

(2015) Laura Baselga-Escudero et al.   NUTRITION RESEARCH

Epigenomes as therapeutic targets

(2015) Christopher A. Hamm et al.   PHARMACOLOGY & THERAPEUTICS

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons

(2015) Yuki Hatanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

(2015) Ali B. Rodgers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of epigenetic “readers, writers and erasers”: Implications for developmental reprogramming and the epigenetic basis for health and disease

(2015) Lindsey S. Treviño et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Epigenetic processes in the male germline

(2015) Alan M. O'Doherty et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

The small RNA content of human sperm reveals pseudogene-derived piRNAs complementary to protein-coding genes

(2015) Lorena Pantano et al.   RNA

Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization

(2015) Jesús García-López et al.   RNA

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

(2015) U. Sharma et al.   SCIENCE

Refurbishing the germline epigenome: Out with the old, in with the new

(2015) Kirsten Hogg et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Sperm mRNAs and microRNAs as candidate markers for the impact of toxicants on human spermatogenesis: an application to tobacco smoking

(2015) Catherine Metzler-Guillemain et al.   Systems Biology in Reproductive Medicine

Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute

(2015) Isabelle R. Miousse et al.   TOXICOLOGY

BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats

(2015) Ying Jiang et al.   TOXICOLOGY

The international regulatory need for tests and information to develop an Integrated Approach to Testing and Assessment (IATA) of non-genotoxic carcinogens

(2015) M. Jacobs et al.   TOXICOLOGY LETTERS

Nickel may contribute to EGFR mutation and synergistically promotes tumor invasion in EGFR-mutated lung cancer via nickel-induced microRNA-21 expression

(2015) Yu-Hu Chiou et al.   TOXICOLOGY LETTERS

Long noncoding RNAs in organogenesis: making the difference

(2015) Phillip Grote et al.   TRENDS IN GENETICS

microRNAs as Developmental Regulators

(2015) Kathryn N. Ivey et al.   Cold Spring Harbor Perspectives in Biology

DNA demethylation by 5-aza-2′-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences

(2015) María-Paz Ramos et al.   Epigenetics & Chromatin

Discovery and Characterization of piRNAs in the Human Fetal Ovary

(2015) Zev Williams et al.   Cell Reports

DNA Methylation Landscapes of Human Fetal Development

(2015) Roderick C. Slieker et al.   PLoS Genetics

Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence

(2015) Adrian Ruiz-Hernandez et al.   Clinical Epigenetics

Human Germline: A New Research Frontier

(2015) M. Azim Surani   Stem Cell Reports

Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep

(2014) Shervi Lie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Early life ethanol exposure causes long-lasting disturbances in rat mesenchymal stem cells via epigenetic modifications

(2014) Yu-Wei Leu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The toxicological application of transcriptomics and epigenomics in zebrafish and other teleosts

(2014) T. D. Williams et al.   Briefings in Functional Genomics

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

(2014) Lan-Tao Gou et al.   CELL RESEARCH

Epigenetic inheritance of metabolic state

(2014) Rebecca A Somer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Epigenetic epidemiology: Promises for public health research

(2014) Kelly M. Bakulski et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

(2014) Jorke H. Kamstra et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

(2014) D. M. Messerschmidt et al.   GENES & DEVELOPMENT

Caenorhabditis elegans: An Old Genetic Model Can Learn New Epigenetic Tricks

(2014) P. A. Padilla et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Maternal allergy increases susceptibility to offspring allergy in association with T H 2-biased epigenetic alterations in a mouse model of peanut allergy

(2014) Ying Song et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human transgenerational responses to early-life experience: potential impact on development, health and biomedical research

(2014) Marcus Pembrey et al.   JOURNAL OF MEDICAL GENETICS

An increased ratio of serum miR-21 to miR-181a levels is associated with the early pathogenic process of chronic obstructive pulmonary disease in asymptomatic heavy smokers

(2014) Lihua Xie et al.   Molecular BioSystems

Editorial - Epigenetics and chemical safety

(2014) Bennard van Ravenzwaay et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice

(2014) Katharina Gapp et al.   NATURE NEUROSCIENCE

Epigenetics: A New Player in the Regulation of Mammalian Puberty

(2014) Paulina A. Rzeczkowska et al.   NEUROENDOCRINOLOGY

NNK-Induced DNA Methyltransferase 1 in Lung Tumorigenesis in A/J Mice and Inhibitory Effects of (−)-Epigallocatechin-3-Gallate

(2014) Huanyu Jin et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Embryonic Caffeine Exposure Acts via A1 Adenosine Receptors to Alter Adult Cardiac Function and DNA Methylation in Mice

(2014) Daniela L. Buscariollo et al.   PLoS One

DNA methylation of BDNF as a biomarker of early-life adversity

(2014) Marija Kundakovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

(2014) K. R. Kilcoyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNAs in spermatogenesis: insights from recent high-throughput transcriptome studies

(2014) Alfred Chun-Shui Luk et al.   REPRODUCTION

5-Hydroxymethylcytosine-Mediated DNA Demethylation in Stem Cells and Development

(2014) Wenjia Sun et al.   STEM CELLS AND DEVELOPMENT

Involvement of EZH2, SUV39H1, G9a and associated molecules in pathogenesis of urethane induced mouse lung tumors: Potential targets for cancer control

(2014) Manuraj Pandey et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Prenatal nicotinic exposure suppresses fetal adrenal steroidogenesis via steroidogenic factor 1 (SF-1) deacetylation

(2014) You-e Yan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro and in vivo testing methods of epigenomic endpoints for evaluating endocrine disruptors

(2014) John Greally   ALTEX-Alternatives to Animal Experimentation

Regulatory non-coding transcripts in spermatogenesis: shedding light on ‘dark matter’

(2014) A. Mukherjee et al.   Andrology

Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice

(2014) Alberto Izzotti et al.   Cancer Medicine

Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment

(2014) Cherry Ignacio et al.   Frontiers in Pediatrics

A Prospective Study of Duration of Smoking Cessation and Colorectal Cancer Risk by Epigenetics-related Tumor Classification

(2013) Reiko Nishihara et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Epigenotoxicity of environmental pollutants evaluated by a combination of DNA methylation inhibition and capillary electrophoresis–laser-induced fluorescence immunoassay

(2013) Xiaoli Wang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor

(2013) Jing Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Periconceptional Undernutrition Programs Changes in Insulin-Signaling Molecules and MicroRNAs in Skeletal Muscle in Singleton and Twin Fetal Sheep1

(2013) Shervi Lie et al.   BIOLOGY OF REPRODUCTION

Phylogenetic and DNA methylation analysis reveal novel regions of variable methylation in the mouse IAP class of transposons

(2013) Christopher Faulk et al.   BMC GENOMICS

Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation

(2013) Z. Herceg et al.   CARCINOGENESIS

Maternal Undernutrition Programs Tissue-Specific Epigenetic Changes in the Glucocorticoid Receptor in Adult Offspring

(2013) Ghazala Begum et al.   ENDOCRINOLOGY

Diabetes, Metabolic Syndrome, and Obesity in Relation to Serum Dioxin Concentrations: The Seveso Women’s Health Study

(2013) Marcella Warner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cigarette smoke induces methylation of the tumor suppressor geneNISCH

(2013) Kimberly Ostrow et al.   Epigenetics

Involvement of epigenetics and microRNA-29b in the urethane induced inception and establishment of mouse lung tumors

(2013) Manuraj Pandey et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells

(2013) Dina G. Kristensen et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

IL-1 Receptor Regulates microRNA-135b Expression in a Negative Feedback Mechanism during Cigarette Smoke-Induced Inflammation

(2013) S. Halappanavar et al.   JOURNAL OF IMMUNOLOGY

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A

(2013) Rong Zhou et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Arsenic-induced promoter hypomethylation and over-expression of ERCC2 reduces DNA repair capacity in humans by non-disjunction of the ERCC2–Cdk7 complex

(2013) Somnath Paul et al.   Metallomics

Gestational exposure to the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin induces BRCA-1 promoter hypermethylation and reduces BRCA-1 expression in mammary tissue of rat offspring: Preventive effects of resveratrol

(2013) Andreas J. Papoutsis et al.   MOLECULAR CARCINOGENESIS

DNA methylation and demethylation: A pathway to gametogenesis and development

(2013) Wendy Dean   MOLECULAR REPRODUCTION AND DEVELOPMENT

Small RNA regulation of reproductive function

(2013) Benjamin J. Hale et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Histone post-translational modifications in preimplantation mouse embryos and their role in nuclear architecture

(2013) Nathalie Beaujean   MOLECULAR REPRODUCTION AND DEVELOPMENT

Promoter methylation represses AT2R gene and increases brain hypoxic–ischemic injury in neonatal rats

(2013) Yong Li et al.   NEUROBIOLOGY OF DISEASE

Methyl Donor Supplementation Blocks the Adverse Effects of Maternal High Fat Diet on Offspring Physiology

(2013) JesseLea Carlin et al.   PLoS One

Vinclozolin—No transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route

(2013) Steffen Schneider et al.   REPRODUCTIVE TOXICOLOGY

Aging-associated excess formaldehyde leads to spatial memory deficits

(2013) Zhiqian Tong et al.   Scientific Reports

RNA–Mediated Epigenetic Heredity Requires the Cytosine Methyltransferase Dnmt2

(2013) Jafar Kiani et al.   PLoS Genetics

CpG Site-Specific Hypermethylation of p16INK4  in Peripheral Blood Lymphocytes of PAH-Exposed Workers

(2012) P. Yang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Dietary Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine-Induced Prostate Carcinogenesis in CYP1A-Humanized Mice

(2012) G. Li et al.   Cancer Prevention Research

Molecular Substrates of Social Avoidance Seen following Prenatal Ethanol Exposure and Its Reversal by Social Enrichment

(2012) Frank A. Middleton et al.   DEVELOPMENTAL NEUROSCIENCE

Smoking induces differential miRNA expression in human spermatozoa: A potential transgenerational epigenetic concern?

(2012) Emma L. Marczylo et al.   Epigenetics

Epigenetics of the male gamete

(2012) Douglas T. Carrell   FERTILITY AND STERILITY

The control of histone methylation and gene expression by oxidative stress, hypoxia, and metals

(2012) Yana Chervona et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking

(2012) Natalie S. Shenker et al.   HUMAN MOLECULAR GENETICS

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

(2012) Andy Boyd et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Dioxin Silences Gonadotropin Expression in Perinatal Pups by Inducing Histone Deacetylases

(2012) Tomoki Takeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Environmental Estrogens Differentially Engage the Histone Methyltransferase EZH2 to Increase Risk of Uterine Tumorigenesis

(2012) K. L. Greathouse et al.   MOLECULAR CANCER RESEARCH

The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

(2012) Stefanie Seisenberger et al.   MOLECULAR CELL

Humans put their eggs in more than one basket

(2012) Diana J. Laird   NATURE CELL BIOLOGY

Multigenerational epigenetic adaptation of the hepatic wound-healing response

(2012) Müjdat Zeybel et al.   NATURE MEDICINE

Low-Dose Cd Induces Hepatic Gene Hypermethylation, along with the Persistent Reduction of Cell Death and Increase of Cell Proliferation in Rats and Mice

(2012) Bo Wang et al.   PLoS One

Maternal exposure to bisphenol A and genistein has minimal effect on Avy/a offspring coat color but favors birth of agouti over nonagouti mice

(2012) C. S. Rosenfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine

(2012) J. A. Hackett et al.   SCIENCE

Perinatal Nicotine Exposure Increases Vulnerability of Hypoxic–Ischemic Brain Injury in Neonatal Rats

(2012) Yong Li et al.   STROKE

Signals and Combinatorial Functions of Histone Modifications

(2011) Tamaki Suganuma et al.   Annual Review of Biochemistry

Prenatal Famine and Adult Health

(2011) L.H. Lumey et al.   Annual Review of Public Health

Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage

(2011) María Pascual et al.   BRAIN BEHAVIOR AND IMMUNITY

Small RNAs in early mammalian development: from gametes to gastrulation

(2011) N. Suh et al.   DEVELOPMENT

Widespread roles of microRNAs during zebrafish development and beyond

(2011) Yuichiro Mishima   DEVELOPMENT GROWTH & DIFFERENTIATION

Dioxin Exposure and Cancer Risk in the Seveso Women’s Health Study

(2011) Marcella Warner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Bisphenol A exposure modifies methylation of imprinted genes in mouse oocytes via the estrogen receptor signaling pathway

(2011) Hu-He Chao et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Environmental chemical exposures and human epigenetics

(2011) Lifang Hou et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

HIstome--a relational knowledgebase of human histone proteins and histone modifying enzymes

(2011) S. P. Khare et al.   NUCLEIC ACIDS RESEARCH

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

(2011) W.-M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

(2011) T. Watanabe et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Involvement of MicroRNAs in Dioxin-Induced Liver Damage in the Mouse

(2011) Wataru Yoshioka et al.   TOXICOLOGICAL SCIENCES

Mammalian Genomic Imprinting

(2011) M. S. Bartolomei et al.   Cold Spring Harbor Perspectives in Biology

Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes

(2010) Zivjena Vucetic et al.   ENDOCRINOLOGY

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

(2010) Ruo-Kai Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development

(2010) Yusuke Ohnishi et al.   NUCLEIC ACIDS RESEARCH

Republished paper: Determinants of child health and development: the contribution of ALSPAC--a personal view of the birth cohort study

(2010) J. Golding   POSTGRADUATE MEDICAL JOURNAL

Animal Models to Study Environmental Epigenetics1

(2009) Cheryl S. Rosenfeld   BIOLOGY OF REPRODUCTION

Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol

(2009) T. Melkamu et al.   CARCINOGENESIS

Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice

(2009) F. Kassie et al.   CARCINOGENESIS

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS

The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth

(2009) V. Grandjean et al.   DEVELOPMENT

In UteroExposure to Di-(2-Ethylhexyl) Phthalate Decreases Mineralocorticoid Receptor Expression in the Adult Testis

(2009) D. B. Martinez-Arguelles et al.   ENDOCRINOLOGY

SUMOylation and deSUMOylation at a glance

(2009) Y. Wang et al.   JOURNAL OF CELL SCIENCE

Use of spermatozoal mRNA profiles to study gene–environment interactions in human germ cells

(2009) Joost O. Linschooten et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

5-methylcytosine in RNA: detection, enzymatic formation and biological functions

(2009) Yuri Motorin et al.   NUCLEIC ACIDS RESEARCH

Early Life Exposure to Famine and Colorectal Cancer Risk: A Role for Epigenetic Mechanisms

(2009) Laura A. E. Hughes et al.   PLoS One

Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics

(2009) David Miller et al.   REPRODUCTION

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Developmental Origins of Health and Disease: Brief History of the Approach and Current Focus on Epigenetic Mechanisms

(2009) Pathik Wadhwa et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations

(2009) Kunifumi Inawaka et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung

(2008) Se-Ran Yang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

RNA Induction and Inheritance of Epigenetic Cardiac Hypertrophy in the Mouse

(2008) Kay D. Wagner et al.   DEVELOPMENTAL CELL

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury

(2008) Natalia Onishchenko et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

(2008) J. Wu et al.   JOURNAL OF NEUROSCIENCE

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome

(2008) Dana C Dolinoy   NUTRITION REVIEWS

Vinclozolin—The lack of a transgenerational effect after oral maternal exposure during organogenesis

(2008) S SCHNEIDER et al.   REPRODUCTIVE TOXICOLOGY