标题
Contributions of alveolar epithelial cell quality control to pulmonary fibrosis
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 130, Issue 10, Pages 5088-5099
出版商
American Society for Clinical Investigation
发表日期
2020-09-02
DOI
10.1172/jci139519
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity, and Stromal Inflammation
- (2020) Stuart A. Cook et al. Annual Review of Medicine
- The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future
- (2020) Maria C. Basil et al. Cell Stem Cell
- New Developments in the Pathogenesis of Pulmonary Cysts in Birt–Hogg–Dubé Syndrome
- (2020) John C. Kennedy et al. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
- Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis
- (2020) Yoshihiko Kobayashi et al. NATURE CELL BIOLOGY
- Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis
- (2020) Maximilian Strunz et al. Nature Communications
- Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
- (2020) Taylor S. Adams et al. Science Advances
- Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis
- (2020) Arun C. Habermann et al. Science Advances
- Revealing the Secrets of Idiopathic Pulmonary Fibrosis
- (2019) Richard K. Albert et al. NEW ENGLAND JOURNAL OF MEDICINE
- In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids
- (2019) Yohei Korogi et al. Stem Cell Reports
- Epithelial Expression of an Interstitial Lung Disease–Associated Mutation in Surfactant Protein-C Modulates Recruitment and Activation of Key Myeloid Cell Populations in Mice
- (2019) Alessandro Venosa et al. JOURNAL OF IMMUNOLOGY
- Activation of mTORC1/PGC1 axis promotes mitochondrial biogenesis and induces cellular senescence in the lung epithelium
- (2019) Ross Summer et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in IPF Airway Epithelia
- (2019) Gang Chen et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Clinical Effectiveness of Antifibrotic Medications for Idiopathic Pulmonary Fibrosis
- (2019) Timothy M. Dempsey et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome
- (2019) Ross Summer et al. Orphanet Journal of Rare Diseases
- PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses
- (2019) Marta Bueno et al. PLoS One
- Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells
- (2019) Alexandros Strikoudis et al. Cell Reports
- Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
- (2019) Benjamin Ng et al. Science Translational Medicine
- MUC5B variant is associated with visually and quantitatively detected preclinical pulmonary fibrosis
- (2019) Susan K Mathai et al. THORAX
- Grp78 Loss in Epithelial Progenitors Reveals an Age-Linked Role for ER Stress in Pulmonary Fibrosis
- (2019) Zea Borok et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis
- (2019) Akio Takezaki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart–lung transplantation Report—2019; Focus theme: Donor and recipient size match
- (2019) Daniel C. Chambers et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Lung regeneration: a tale of mice and men
- (2019) Maria C. Basil et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome
- (2019) Sneha Sitaraman et al. Scientific Reports
- Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells
- (2019) Huijuan Wu et al. CELL
- ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis
- (2018) Marta Bueno et al. AGING CELL
- Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes
- (2018) Seunghyi Kook et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Involvement of Alveolar Epithelial Cell Necroptosis in IPF Pathogenesis.
- (2018) Ji-Min Lee et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- High levels of IL-6 and IL-8 characterize early-on idiopathic pulmonary fibrosis acute exacerbations
- (2018) Spyros A. Papiris et al. CYTOKINE
- Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
- (2018) Jonathan A. Kropski et al. JOURNAL OF CLINICAL INVESTIGATION
- Idiopathic Pulmonary Fibrosis
- (2018) David J. Lederer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study
- (2018) Amy Dressen et al. Lancet Respiratory Medicine
- Expression of mutant Sftpc in murine alveolar epithelia drives spontaneous lung fibrosis
- (2018) Shin-Ichi Nureki et al. JOURNAL OF CLINICAL INVESTIGATION
- Lung injury and fibrosis induced by a mutant form of surfactant protein C
- (2018) Timothy S. Blackwell JOURNAL OF CLINICAL INVESTIGATION
- Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
- (2018) Paul A Reyfman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice
- (2018) Laura A. Hancock et al. Nature Communications
- SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis
- (2017) Renea P. Jablonski et al. FASEB JOURNAL
- EMC3 coordinates surfactant protein and lipid homeostasis required for respiration
- (2017) Xiaofang Tang et al. JOURNAL OF CLINICAL INVESTIGATION
- Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
- (2017) Alexander V. Misharin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Local lung hypoxia determines epithelial fate decisions during alveolar regeneration
- (2017) Ying Xi et al. NATURE CELL BIOLOGY
- Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function
- (2017) Guoying Yu et al. NATURE MEDICINE
- Short telomere length in IPF lung associates with fibrotic lesions and predicts survival
- (2017) Reinier Snetselaar et al. PLoS One
- Cellular senescence mediates fibrotic pulmonary disease
- (2017) Marissa J. Schafer et al. Nature Communications
- Cellular Senescence: A Translational Perspective
- (2017) James L. Kirkland et al. EBioMedicine
- Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report
- (2016) Harold R. Collard et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair
- (2016) Orquidea Garcia et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Coordinate regulation of autophagy and the ubiquitin proteasome system by MTOR
- (2016) Jinghui Zhao et al. Autophagy
- Incidence and prevalence of idiopathic pulmonary fibrosis in US adults 18–64 years old
- (2016) Ganesh Raghu et al. EUROPEAN RESPIRATORY JOURNAL
- Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive
- (2016) Chad A. Newton et al. EUROPEAN RESPIRATORY JOURNAL
- GermlineSFTPA1mutation in familial idiopathic interstitial pneumonia and lung cancer
- (2016) Nadia Nathan et al. HUMAN MOLECULAR GENETICS
- Pulmonary Involvement in Niemann–Pick Disease: A State-of-the-Art Review
- (2016) Felipe Mussi von Ranke et al. LUNG
- Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease
- (2015) Surafel Mulugeta et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- A non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy
- (2015) Arie Hawkins et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Rare Variants inRTEL1Are Associated with Familial Interstitial Pneumonia
- (2015) Joy D. Cogan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- SFTPA2Mutations in Familial and Sporadic Idiopathic Interstitial Pneumonia
- (2015) Coline H. M. van Moorsel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Role of Cigarette Smoke–Induced Aggresome Formation in Chronic Obstructive Pulmonary Disease–Emphysema Pathogenesis
- (2015) Ian Tran et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Thyroid Disease Is Prevalent and Predicts Survival in Patients With Idiopathic Pulmonary Fibrosis
- (2015) Justin M. Oldham et al. CHEST
- CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab
- (2015) Ganesh Raghu et al. EUROPEAN RESPIRATORY JOURNAL
- A meta-analysis examining the association between the MUC5B rs35705950 T/G polymorphism and susceptibility to idiopathic pulmonary fibrosis
- (2015) Min-Gu Lee et al. INFLAMMATION RESEARCH
- Telomere dysfunction causes alveolar stem cell failure
- (2015) Jonathan K. Alder et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction
- (2015) Juan M. Povedano et al. Cell Reports
- Genotype–Phenotype Correlations for Infants and Children with ABCA3 Deficiency
- (2014) Jennifer A. Wambach et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Regulation of the Proteasome: Evaluating the Lung Proteasome as a New Therapeutic Target
- (2014) Silke Meiners et al. ANTIOXIDANTS & REDOX SIGNALING
- PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
- (2014) Marta Bueno et al. JOURNAL OF CLINICAL INVESTIGATION
- ER Stress Response in Human Cellular Models of Senescence
- (2014) Liliana Matos et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- p63+Krt5+ distal airway stem cells are essential for lung regeneration
- (2014) Wei Zuo et al. NATURE
- Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury
- (2014) Andrew E. Vaughan et al. NATURE
- A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
- (2014) Talmadge E. King et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis
- (2014) Luca Richeldi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK
- (2014) Elena A. Goncharova et al. Cell Reports
- An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias
- (2013) William D. Travis et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Telomerase and Telomere Length in Pulmonary Fibrosis
- (2013) Tianju Liu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Asbestos-Induced Alveolar Epithelial Cell Apoptosis. The Role of Endoplasmic Reticulum Stress Response
- (2013) David W. Kamp et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Acute exacerbation of idiopathic pulmonary fibrosis associated with air pollution exposure
- (2013) K. A. Johannson et al. EUROPEAN RESPIRATORY JOURNAL
- Telomeres and age-related disease: how telomere biology informs clinical paradigms
- (2013) Mary Armanios JOURNAL OF CLINICAL INVESTIGATION
- Type 2 alveolar cells are stem cells in adult lung
- (2013) Christina E. Barkauskas et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of mitochondria in aging
- (2013) Ana Bratic et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Idiopathic Pulmonary Fibrosis Honeycomb Cyst Contains A Mucocilary Pseudostratified Epithelium
- (2013) Max A. Seibold et al. PLoS One
- Higher serum CCL17 may be a promising predictor of acute exacerbations in chronic hypersensitivity pneumonitis
- (2013) Yasunari Miyazaki et al. RESPIRATORY RESEARCH
- Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease
- (2013) Sovan Sarkar et al. Cell Reports
- The Alveolar Epithelium Determines Susceptibility to Lung Fibrosis in Hermansky-Pudlak Syndrome
- (2012) Lisa R. Young et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Role of Endoplasmic Reticulum Stress in Age-Related Susceptibility to Lung Fibrosis
- (2012) Edilson Torres-González et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Telomerase deficiency does not alter bleomycin-induced fibrosis in mice
- (2012) Amber L. Degryse et al. EXPERIMENTAL LUNG RESEARCH
- High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C
- (2012) H. Willander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- Viral Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
- (2011) Sharon Chao Wootton et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Long-term Course and Prognosis of Idiopathic Pulmonary Fibrosis in the New Millennium
- (2011) Steven D. Nathan et al. CHEST
- Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis
- (2011) J. S. Lee et al. EUROPEAN RESPIRATORY JOURNAL
- A CommonMUC5BPromoter Polymorphism and Pulmonary Fibrosis
- (2011) Max A. Seibold et al. NEW ENGLAND JOURNAL OF MEDICINE
- Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
- (2011) W. E. Lawson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis
- (2011) L. Plantier et al. THORAX
- Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues
- (2010) Suzette Laing et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice
- (2010) Valérie Besnard et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis
- (2010) Harold R. Collard et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Acute exacerbation of idiopathic pulmonary fibrosis: incidence, risk factors and outcome
- (2010) J. W. Song et al. EUROPEAN RESPIRATORY JOURNAL
- Surfactant Protein A2 Mutations Associated with Pulmonary Fibrosis Lead to Protein Instability and Endoplasmic Reticulum Stress
- (2010) Meenakshi Maitra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Heightened Endoplasmic Reticulum Stress in the Lungs of Patients with Chronic Obstructive Pulmonary Disease
- (2009) Deepti Malhotra et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis
- (2009) Thomas H. Sisson et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Genetic Disorders of Surfactant Dysfunction
- (2009) Susan E. Wert et al. PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
- Genetic Defects in Surfactant Protein A2 Are Associated with Pulmonary Fibrosis and Lung Cancer
- (2008) Yongyu Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection
- (2008) William E. Lawson et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis
- (2008) Martina Korfei et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Structure of pulmonary surfactant membranes and films: The role of proteins and lipid–protein interactions
- (2008) Jesús Pérez-Gil BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Short telomeres are a risk factor for idiopathic pulmonary fibrosis
- (2008) J. K. Alder et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
- Cigarette Smoke Induces an Unfolded Protein Response in the Human Lung
- (2007) Steven G. Kelsen et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started