ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis

Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis

(2017) Ana L. Mora et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitonuclear communication in homeostasis and stress

(2016) Pedro M. Quirós et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1

(2015) Meredith L. Sosulski et al.   AGING CELL

Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis

(2015) Tatjana Mallano et al.   ANNALS OF THE RHEUMATIC DISEASES

Acrylamide Induces Senescence in Macrophages through a Process Involving ATF3, ROS, p38/JNK, and a Telomerase-Independent Pathway

(2015) Kyung-Ho Kim et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis

(2015) Avignat S. Patel et al.   PLoS One

NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions

(2015) Hitoshi Murata et al.   PLoS One

Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model

(2014) Moisés Selman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PTENα, a PTEN Isoform Translated through Alternative Initiation, Regulates Mitochondrial Function and Energy Metabolism

(2014) Hui Liang et al.   Cell Metabolism

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

(2014) Marta Bueno et al.   JOURNAL OF CLINICAL INVESTIGATION

Upregulation of human PINK1 gene expression by NFκB signalling

(2014) Xiaoling Duan et al.   Molecular Brain

Transcription factor ATF3 links host adaptive response to breast cancer metastasis

(2013) Chris C. Wolford et al.   JOURNAL OF CLINICAL INVESTIGATION

Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy

(2013) Lilach Koren et al.   PLoS One

Epithelial Pten Controls Acute Lung Injury and Fibrosis by Regulating Alveolar Epithelial Cell Integrity

(2012) Kahori Miyoshi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Endoplasmic Reticulum Stress in Age-Related Susceptibility to Lung Fibrosis

(2012) Edilson Torres-González et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pulmonary fibrosis: patterns and perpetrators

(2012) Paul W. Noble et al.   JOURNAL OF CLINICAL INVESTIGATION

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Activating Transcription Factor 3 Deficiency Promotes Cardiac Hypertrophy, Dysfunction, and Fibrosis Induced by Pressure Overload

(2011) Heng Zhou et al.   PLoS One

Pathologic Caveolin-1 Regulation of PTEN in Idiopathic Pulmonary Fibrosis

(2010) Hong Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells

(2010) Shunsuke Minagawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ATF3, a Hub of the Cellular Adaptive-Response Network, in the Pathogenesis of Diseases: Is Modulation of Inflammation a Unifying Component?

(2010) TSONWIN HAI et al.   GENE EXPRESSION

The Roles ofATF3, an Adaptive-Response Gene, in High-Fat-Diet-Induced Diabetes and Pancreatic β-Cell Dysfunction

(2010) Erik J. Zmuda et al.   MOLECULAR ENDOCRINOLOGY

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

(2009) Y. Mei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

(2008) Hong Xia et al.   JOURNAL OF EXPERIMENTAL MEDICINE