Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease
出版年份 2015 全文链接
标题
Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease
作者
关键词
-
出版物
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Volume 309, Issue 6, Pages L507-L525
出版商
American Physiological Society
发表日期
2015-07-18
DOI
10.1152/ajplung.00139.2015
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy
- (2015) Arie Hawkins et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Extensive Phenotyping of Individuals at Risk for Familial Interstitial Pneumonia Reveals Clues to the Pathogenesis of Interstitial Lung Disease
- (2015) Jonathan A. Kropski et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Essential role for autophagy in life span extension
- (2015) Frank Madeo et al. JOURNAL OF CLINICAL INVESTIGATION
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Telomere dysfunction causes alveolar stem cell failure
- (2015) Jonathan K. Alder et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor
- (2014) Jibing Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Genotype–Phenotype Correlations for Infants and Children with ABCA3 Deficiency
- (2014) Jennifer A. Wambach et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model
- (2014) Moisés Selman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Reserve Autophagic Capacity in Alveolar Epithelia Provides a Replicative Niche for Influenza A Virus
- (2014) David R. Hahn et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulation of the Proteasome: Evaluating the Lung Proteasome as a New Therapeutic Target
- (2014) Silke Meiners et al. ANTIOXIDANTS & REDOX SIGNALING
- Telomerase mutations in smokers with severe emphysema
- (2014) Susan E. Stanley et al. JOURNAL OF CLINICAL INVESTIGATION
- PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
- (2014) Marta Bueno et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy: a potential therapeutic target in lung diseases
- (2013) Kiichi Nakahira et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Abrogation of ER stress-induced apoptosis of alveolar epithelial cells by angiotensin 1–7
- (2013) Bruce D. Uhal et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3
- (2013) Michael F. Beers et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- The Witschi Hypothesis revisited after 35 years: genetic proof from SP-C BRICHOS domain mutations
- (2013) Bruce D. Uhal et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- An Official American Thoracic Society Clinical Practice Guideline: Classification, Evaluation, and Management of Childhood Interstitial Lung Disease in Infancy
- (2013) Geoffrey Kurland et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report
- (2013) Timothy S. Blackwell et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- SFTPCmutations cause SP-C degradation and aggregate formation without increasing ER stress
- (2013) Tobias Thurm et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Acute exacerbation of idiopathic pulmonary fibrosis associated with air pollution exposure
- (2013) K. A. Johannson et al. EUROPEAN RESPIRATORY JOURNAL
- Association Between the MUC5B Promoter Polymorphism and Survival in Patients With Idiopathic Pulmonary Fibrosis
- (2013) Anna L. Peljto et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Functional and morphological impact of ER stress on mitochondria
- (2013) Kayleen Vannuvel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Type 2 alveolar cells are stem cells in adult lung
- (2013) Christina E. Barkauskas et al. JOURNAL OF CLINICAL INVESTIGATION
- The autophagosome: origins unknown, biogenesis complex
- (2013) Christopher A. Lamb et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease
- (2013) Sovan Sarkar et al. Cell Reports
- Acute cigarette smoke exposure impairs proteasome function in the lung
- (2012) Sabine H. van Rijt et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis
- (2012) Harikrishna Tanjore et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Insufficient autophagy in idiopathic pulmonary fibrosis
- (2012) Jun Araya et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- The Alveolar Epithelium Determines Susceptibility to Lung Fibrosis in Hermansky-Pudlak Syndrome
- (2012) Lisa R. Young et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- 4-Phenylbutyric Acid Treatment Rescues Trafficking and Processing of a Mutant Surfactant Protein–C
- (2012) Gareth A. Stewart et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
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- (2012) Edilson Torres-González et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Crosstalk between the ubiquitin–proteasome system and autophagy in a human cellular model of Alzheimer's disease
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- (2012) Rene L. Vidal et al. HUMAN MOLECULAR GENETICS
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- Acute Inducible Ablation of GRP78 Reveals Its Role in Hematopoietic Stem Cell Survival, Lymphogenesis and Regulation of Stress Signaling
- (2012) Shiuan Wey et al. PLoS One
- Autophagy in Idiopathic Pulmonary Fibrosis
- (2012) Avignat S. Patel et al. PLoS One
- High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C
- (2012) H. Willander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF- 1 secretion
- (2012) M. Maitra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- The Mammalian Endoplasmic Reticulum-Associated Degradation System
- (2012) J. A. Olzmann et al. Cold Spring Harbor Perspectives in Biology
- The surfactant protein C mutation A116D alters cellular processing, stress tolerance, surfactant lipid composition, and immune cell activation
- (2012) Ralf Zarbock et al. BMC Pulmonary Medicine
- Right place, right time: the evolving role of herpesvirus infection as a “second hit” in idiopathic pulmonary fibrosis
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- (2011) Elena N. Atochina-Vasserman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Surfactant protein C G100S mutation causes familial pulmonary fibrosis in Japanese kindred
- (2011) S. Ono et al. EUROPEAN RESPIRATORY JOURNAL
- BRICHOS domain associated with lung fibrosis, dementia and cancer - a chaperone that prevents amyloid fibril formation?
- (2011) Hanna Willander et al. FEBS Journal
- The role of ubiquitin–proteasome system in ageing
- (2011) Peter Löw GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Multiple ways to die: Delineation of the unfolded protein response and apoptosis induced by Surfactant Protein C BRICHOS mutants
- (2011) Jean Ann Maguire et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress
- (2011) Harikrishna Tanjore et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The three R’s of lung health and disease: repair, remodeling, and regeneration
- (2011) Michael F. Beers et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrating mechanisms of pulmonary fibrosis
- (2011) Thomas A. Wynn JOURNAL OF EXPERIMENTAL MEDICINE
- A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments
- (2011) Michael F. Beers et al. JOURNAL OF LIPID RESEARCH
- Idiopathic pulmonary fibrosis
- (2011) Talmadge E King et al. LANCET
- A CommonMUC5BPromoter Polymorphism and Pulmonary Fibrosis
- (2011) Max A. Seibold et al. NEW ENGLAND JOURNAL OF MEDICINE
- Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
- (2011) W. E. Lawson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Nonaggregating Surfactant Protein C Mutant Is Misdirected to Early Endosomes and Disrupts Phospholipid Recycling
- (2011) Michael F. Beers et al. TRAFFIC
- Pathway to lamellar bodies for surfactant protein A
- (2010) Aron B. Fisher et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Surfactant Protein C Mutations Are the Basis of a Significant Portion of Adult Familial Pulmonary Fibrosis in a Dutch Cohort
- (2010) Coline H. M. van Moorsel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Endoplasmic Reticulum Stress Induced by Surfactant Protein C BRICHOS Mutants Promotes Proinflammatory Signaling by Epithelial Cells
- (2010) Jean Ann Maguire et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Role of Endoplasmic Reticulum Stress in Epithelial–Mesenchymal Transition of Alveolar Epithelial Cells
- (2010) Qian Zhong et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Mitophagy Selectively Degrades Individual Damaged Mitochondria After Photoirradiation
- (2010) Insil Kim et al. ANTIOXIDANTS & REDOX SIGNALING
- Identification of Early Interstitial Lung Disease in an Individual With Genetic Variations in ABCA3 and SFTPC
- (2010) Peter F. Crossno et al. CHEST
- The surfactant lipid transporter ABCA3 is N-terminally cleaved inside LAMP3-positive vesicles
- (2010) Stefanie Engelbrecht et al. FEBS LETTERS
- Surfactant Protein A2 Mutations Associated with Pulmonary Fibrosis Lead to Protein Instability and Endoplasmic Reticulum Stress
- (2010) Meenakshi Maitra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective autophagy: ubiquitin-mediated recognition and beyond
- (2010) Claudine Kraft et al. NATURE CELL BIOLOGY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Infants and Young Children with Children's Interstitial Lung Disease
- (2010) Robin R. Deterding Pediatric Allergy Immunology and Pulmonology
- Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection
- (2009) Stephan W. Glasser et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Nedd4-2–Mediated Ubiquitination Facilitates Processing of Surfactant Protein–C
- (2009) Juliana J. Conkright et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy
- (2009) Soledad Matus et al. Autophagy
- Aberrant Processing Forms of Lung Surfactant Proteins SP–B and SP–C Revealed by High-Resolution Mass Spectrometry
- (2009) Dmitry Galetskiy et al. EUROPEAN JOURNAL OF MASS SPECTROMETRY
- Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo
- (2009) Sadis Matalon et al. FASEB JOURNAL
- Anterograde Transport of Surfactant Protein C Proprotein to Distal Processing Compartments Requires PPDY-mediated Association with Nedd4 Ubiquitin Ligases
- (2009) Adam Kotorashvili et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice
- (2009) Hélène L. Kammoun et al. JOURNAL OF CLINICAL INVESTIGATION
- New surfactant protein C gene mutations associated with diffuse lung disease
- (2009) L Guillot et al. JOURNAL OF MEDICAL GENETICS
- Genetic Disorders of Surfactant Dysfunction
- (2009) Susan E. Wert et al. PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
- Familial interstitial disease with I73T mutation: A mid- and long-term study
- (2009) Rola Abou Taam et al. PEDIATRIC PULMONOLOGY
- Genetic Defects in Surfactant Protein A2 Are Associated with Pulmonary Fibrosis and Lung Cancer
- (2008) Yongyu Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Aberrant catalytic cycle and impaired lipid transport into intracellular vesicles in ABCA3 mutants associated with nonfatal pediatric interstitial lung disease
- (2008) Yoshihiro Matsumura et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection
- (2008) William E. Lawson et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis
- (2008) Martina Korfei et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology
- (2008) Alan L. Schwartz et al. Annual Review of Pharmacology and Toxicology
- Structure of pulmonary surfactant membranes and films: The role of proteins and lipid–protein interactions
- (2008) Jesús Pérez-Gil BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
- (2008) R. I. Morimoto GENES & DEVELOPMENT
- ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C
- (2008) Mei Dong et al. MOLECULAR BIOLOGY OF THE CELL
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- From endoplasmic-reticulum stress to the inflammatory response
- (2008) Kezhong Zhang et al. NATURE
- Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
- (2008) Inki Kim et al. NATURE REVIEWS DRUG DISCOVERY
- One step at a time: endoplasmic reticulum-associated degradation
- (2008) Shruthi S. Vembar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
- S-Nitrosylation of Surfactant Protein-D Controls Inflammatory Function
- (2008) Chang-Jiang Guo et al. PLOS BIOLOGY
- Cigarette Smoke Induces an Unfolded Protein Response in the Human Lung
- (2007) Steven G. Kelsen et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
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