ER Stress Response in Human Cellular Models of Senescence

Regulation of G1 Arrest and Apoptosis in Hypoxia by PERK and GCN2-Mediated eIF2α Phosphorylation

(2015) Yan Liu et al.   NEOPLASIA

The Role of Macromolecular Damage in Aging and Age-related Disease

(2014) A. G. Richardson et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Proteostasis and the Aging Proteome in Health and Disease

(2014) R. I. Morimoto et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Metabolism and functions of copper in brain

(2014) Ivo F. Scheiber et al.   PROGRESS IN NEUROBIOLOGY

Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response

(2014) Vyacheslav M. Labunskyy et al.   PLoS Genetics

Role of p38MAPK and oxidative stress in copper-induced senescence

(2013) Emmanuelle Boilan et al.   AGE

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

(2013) Wafa B’chir et al.   NUCLEIC ACIDS RESEARCH

Suppression of XBP1S Mediates High Glucose-Induced Oxidative Stress and Extracellular Matrix Synthesis in Renal Mesangial Cell and Kidney of Diabetic Rats

(2013) Decui Shao et al.   PLoS One

New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia

(2013) Dan Cojocari et al.   RADIOTHERAPY AND ONCOLOGY

A Novel Feedback Loop Regulates the Response to Endoplasmic Reticulum Stress via the Cooperation of Cytoplasmic Splicing and mRNA Translation

(2012) M. Majumder et al.   MOLECULAR AND CELLULAR BIOLOGY

miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner

(2012) Nilesh S. Chitnis et al.   MOLECULAR CELL

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

(2012) B. C. S. Cross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper ability to induce premature senescence in human fibroblasts

(2011) Liliana Matos et al.   AGE

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity

(2010) S. Henis-Korenblit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER and aging—Protein folding and the ER stress response

(2009) Nirinjini Naidoo   AGEING RESEARCH REVIEWS

IRE1α controls cyclin A1 expression and promotes cell proliferation through XBP-1

(2009) Jeffery A. Thorpe et al.   CELL STRESS & CHAPERONES

HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans

(2009) Di Chen et al.   PLoS Genetics

Cellular Senescence: Molecular Mechanisms, In Vivo Significance, and Redox Considerations

(2008) Michael Muller   ANTIOXIDANTS & REDOX SIGNALING

Aging Impairs the Unfolded Protein Response to Sleep Deprivation and Leads to Proapoptotic Signaling

(2008) N. Naidoo et al.   JOURNAL OF NEUROSCIENCE

Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers

(2007) Jonathan E. Nuss et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS