Methods Favoring Homology-Directed Repair Choice in Response to CRISPR/Cas9 Induced-Double Strand Breaks
出版年份 2020 全文链接
标题
Methods Favoring Homology-Directed Repair Choice in Response to CRISPR/Cas9 Induced-Double Strand Breaks
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 18, Pages 6461
出版商
MDPI AG
发表日期
2020-09-04
DOI
10.3390/ijms21186461
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- DNA repair protein RAD51 enhances the CRISPR/Cas9-mediated knock-in efficiency in brain neurons
- (2020) Taiga Kurihara et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- 53BP1: a DSB escort
- (2020) Zachary Mirman et al. GENES & DEVELOPMENT
- The promise and challenge of therapeutic genome editing
- (2020) Jennifer A. Doudna NATURE
- Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
- (2020) Beeke Wienert et al. Nature Communications
- Shieldin – the protector of DNA ends
- (2019) Dheva Setiaputra et al. EMBO REPORTS
- The next generation of CRISPR–Cas technologies and applications
- (2019) Adrian Pickar-Oliver et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors
- (2019) Ngoc-Tung Tran et al. Frontiers in Genetics
- Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant
- (2019) Tarun S. Nambiar et al. Nature Communications
- CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites
- (2019) Rajeswari Jayavaradhan et al. Nature Communications
- CRISPR-Cas9 system: A new-fangled dawn in gene editing
- (2019) Darshana Gupta et al. LIFE SCIENCES
- Simultaneous precise editing of multiple genes in human cells
- (2019) Stephan Riesenberg et al. NUCLEIC ACIDS RESEARCH
- CRISPR/Cas: from adaptive immune system in prokaryotes to therapeutic weapon against immune-related diseases
- (2019) Juan Esteban Garcia-Robledo et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing
- (2019) Nina Reuven et al. Biomolecules
- A Mechanism to Minimize Errors during Non-homologous End Joining
- (2019) Benjamin M. Stinson et al. MOLECULAR CELL
- Suppressing Ku70/Ku80 expression elevates homology-directed repair efficiency in primary fibroblasts
- (2018) Guoling Li et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- An efficient platform for generating somatic point mutations with germline transmission in the zebrafish by CRISPR/Cas9-mediated gene editing
- (2018) Yibo Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Versatile Tool for the Quantification of CRISPR/Cas9-Induced Genome Editing Events in Human Hematopoietic Cell Lines and Hematopoietic Stem/Progenitor Cells
- (2018) Rajeswari Jayavaradhan et al. JOURNAL OF MOLECULAR BIOLOGY
- L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
- (2018) Somaira Nowsheen et al. NATURE CELL BIOLOGY
- RPA and RAD51: fork reversal, fork protection, and genome stability
- (2018) Kamakoti P. Bhat et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair
- (2018) M. Charpentier et al. Nature Communications
- Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells
- (2018) Stephan Riesenberg et al. Nature Communications
- RPA and RAD51: fork reversal, fork protection, and genome stability
- (2018) Kamakoti P. Bhat et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR–Cas9 and ssODN in human cancer cells
- (2018) Zheng Hu et al. Cell and Bioscience
- Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair
- (2018) Natasa Savic et al. eLife
- Efficient Knock-in of a Point Mutation in Porcine Fibroblasts Using the CRISPR/Cas9-GMNN Fusion Gene
- (2018) Max Gerlach et al. Genes
- The shieldin complex mediates 53BP1-dependent DNA repair
- (2018) Sylvie M. Noordermeer et al. NATURE
- Precision gene editing technology and applications in nephrology
- (2018) Zachary WareJoncas et al. Nature Reviews Nephrology
- Programmable DNA repair with CRISPRa/i enhanced homology-directed repair efficiency with a single Cas9
- (2018) Lupeng Ye et al. Cell Discovery
- 53BP1: A key player of DNA damage response with critical functions in cancer
- (2018) Mohammad Mirza-Aghazadeh-Attari et al. DNA REPAIR
- CRISPR-Based Technologies: Impact of RNA-Targeting Systems
- (2018) Michael P. Terns MOLECULAR CELL
- Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair
- (2018) Anastasia Lomova et al. STEM CELLS
- Enhancing CRISPR/Cas9-mediated homology-directed repair in mammalian cells by expressing Saccharomyces cerevisiae Rad52
- (2017) Simin Shao et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA
- (2017) Xiquan Liang et al. JOURNAL OF BIOTECHNOLOGY
- ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
- (2017) Andrew N. Blackford et al. MOLECULAR CELL
- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
- (2017) Nausica Arnoult et al. NATURE
- Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency
- (2017) Marella D Canny et al. NATURE BIOTECHNOLOGY
- Non-homologous DNA end joining and alternative pathways to double-strand break repair
- (2017) Howard H. Y. Chang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing
- (2017) Jared Carlson-Stevermer et al. Nature Communications
- Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair
- (2017) Huiming Lu et al. Nature Communications
- Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts
- (2017) Zicong Xie et al. Scientific Reports
- Microhomology-mediated end joining: new players join the team
- (2017) Hailong Wang et al. Cell and Bioscience
- DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining
- (2017) Michael P. Conlin et al. Cell Reports
- Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP
- (2017) James M. Daley et al. Cell Reports
- BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation
- (2017) Mayu Isono et al. Cell Reports
- Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks
- (2017) Fei Song et al. Molecular Therapy-Nucleic Acids
- Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR–Cas9 genome editing
- (2017) Bruna S. Paulsen et al. Nature Biomedical Engineering
- Enhancing Targeted Genomic DNA Editing in Chicken Cells Using the CRISPR/Cas9 System
- (2017) Ling Wang et al. PLoS One
- Small molecules enhance CRISPR/Cas9-mediated homology-directed genome editing in primary cells
- (2017) Guoling Li et al. Scientific Reports
- Mechanism and regulation of DNA end resection in eukaryotes
- (2016) Lorraine S. Symington CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
- (2016) George E. Greco et al. DNA REPAIR
- The Ku70 80 ring in Non-Homologous End-Joining easy to slip on hard to remove
- (2016) Guido Keijzers Frontiers in Bioscience-Landmark
- HELB Is a Feedback Inhibitor of DNA End Resection
- (2016) Ján Tkáč et al. MOLECULAR CELL
- In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
- (2016) Keiichiro Suzuki et al. NATURE
- Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
- (2016) Christopher D Richardson et al. NATURE BIOTECHNOLOGY
- Applications of CRISPR technologies in research and beyond
- (2016) Rodolphe Barrangou et al. NATURE BIOTECHNOLOGY
- Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers
- (2016) Petra Schwertman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Human BRCA1–BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection
- (2016) Ruth M Densham et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Increasing the efficiency of CRISPR/Cas9-mediated precise genome editing in rats by inhibiting NHEJ and using Cas9 protein
- (2016) Yuanwu Ma et al. RNA Biology
- Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
- (2016) F. Jiang et al. SCIENCE
- Regulation of Single-Strand Annealing and its Role in Genome Maintenance
- (2016) Ragini Bhargava et al. TRENDS IN GENETICS
- RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
- (2016) Jun Song et al. Nature Communications
- A cell cycle-dependent BRCA1–UHRF1 cascade regulates DNA double-strand break repair pathway choice
- (2016) Haoxing Zhang et al. Nature Communications
- Human BRCA1–BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection
- (2016) Ruth M Densham et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
- (2016) Huiming Lu et al. Cell Reports
- Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair
- (2016) Tony Gutschner et al. Cell Reports
- A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells
- (2016) Sara E. Howden et al. Stem Cell Reports
- Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMO
- (2016) Sarah-Felicitas Himmels et al. Frontiers in Genetics
- Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases
- (2016) Diane Yang et al. Scientific Reports
- Small Molecules Enhance CRISPR Genome Editing in Pluripotent Stem Cells
- (2015) Chen Yu et al. Cell Stem Cell
- Inhibition of nonhomologous end joining to increase the specificity of CRISPR/Cas9 genome editing
- (2015) Supriya V. Vartak et al. FEBS Journal
- The Ku heterodimer: Function in DNA repair and beyond
- (2015) Victoria L. Fell et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
- (2015) Pedro A. Mateos-Gomez et al. NATURE
- Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
- (2015) Takeshi Maruyama et al. NATURE BIOTECHNOLOGY
- Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
- (2015) Van Trung Chu et al. NATURE BIOTECHNOLOGY
- The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice
- (2015) Ismail Hassan Ismail et al. NATURE CELL BIOLOGY
- Therapeutic genome editing: prospects and challenges
- (2015) David Benjamin Turitz Cox et al. NATURE MEDICINE
- MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
- (2015) Tetsushi Sakuma et al. Nature Protocols
- Nuclear domain ‘knock-in’ screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing
- (2015) Jordan Pinder et al. NUCLEIC ACIDS RESEARCH
- Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?
- (2015) Agnel Sfeir et al. TRENDS IN BIOCHEMICAL SCIENCES
- Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites
- (2015) Jessica S. Brown et al. Cell Reports
- Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing
- (2015) Francis Robert et al. Genome Medicine
- Making designer mutants in model organisms
- (2014) Y. Peng et al. DEVELOPMENT
- DNA-PK: A dynamic enzyme in a versatile DSB repair pathway
- (2014) Anthony J. Davis et al. DNA REPAIR
- APC/CCdh1controls CtIP stability during the cell cycle and in response to DNA damage
- (2014) Lorenzo Lafranchi et al. EMBO JOURNAL
- PTIP associates with Artemis to dictate DNA repair pathway choice
- (2014) Jiadong Wang et al. GENES & DEVELOPMENT
- A Mouse Geneticist's Practical Guide to CRISPR Applications
- (2014) P. Singh et al. GENETICS
- Mechanisms and principles of homology search during recombination
- (2014) Jörg Renkawitz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice
- (2014) Nozomi Tomimatsu et al. Nature Communications
- Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
- (2014) Shota Nakade et al. Nature Communications
- BRCA1 Accelerates CtIP-Mediated DNA-End Resection
- (2014) Andrés Cruz-García et al. Cell Reports
- Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
- (2014) Steven Lin et al. eLife
- DNA DSB repair pathway choice: an orchestrated handover mechanism
- (2013) A Kakarougkas et al. BRITISH JOURNAL OF RADIOLOGY
- Prolyl Isomerase PIN1 Regulates DNA Double-Strand Break Repair by Counteracting DNA End Resection
- (2013) Martin Steger et al. MOLECULAR CELL
- A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
- (2013) Cristina Escribano-Díaz et al. MOLECULAR CELL
- Double-strand break repair: 53BP1 comes into focus
- (2013) Stephanie Panier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA damage emergency: cellular garbage disposal to the rescue?
- (2013) H R Stone et al. ONCOGENE
- Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
- (2013) L. N. Truong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Donor DNA Utilization During Gene Targeting with Zinc-Finger Nucleases
- (2013) Kelly J. Beumer et al. G3-Genes Genomes Genetics
- Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic Advancement
- (2012) B. H. Lok et al. CLINICAL CANCER RESEARCH
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
- (2012) J. Ross Chapman et al. MOLECULAR CELL
- Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2
- (2012) Jeffrey Buis et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
- (2012) Lin Feng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Double-Strand Break End Resection and Repair Pathway Choice
- (2011) Lorraine S. Symington et al. Annual Review of Genetics
- Trex2 Enables Spontaneous Sister Chromatid Exchanges Without Facilitating DNA Double-Strand Break Repair
- (2011) Lavinia C. Dumitrache et al. GENETICS
- Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
- (2011) Valerie Garcia et al. NATURE
- CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
- (2011) Elitza Deltcheva et al. NATURE
- Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
- (2011) Qiao Cheng et al. NUCLEIC ACIDS RESEARCH
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Regulation of Homologous Recombination in Eukaryotes
- (2010) Wolf-Dietrich Heyer et al. Annual Review of Genetics
- DNA resection in eukaryotes: deciding how to fix the break
- (2010) Pablo Huertas NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The search for a human Holliday junction resolvase
- (2009) Stephen C. West BIOCHEMICAL SOCIETY TRANSACTIONS
- Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
- (2009) Pablo Huertas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Short motif sequences determine the targets of the prokaryotic CRISPR defence system
- (2009) MICROBIOLOGY-SGM
- Mechanism of Eukaryotic Homologous Recombination
- (2008) Joseph San Filippo et al. Annual Review of Biochemistry
- Cyclin-dependent kinases and cell-cycle transitions: does one fit all?
- (2008) Helfrid Hochegger et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A chemical compound that stimulates the human homologous recombination protein RAD51
- (2008) K. Jayathilaka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now