标题
53BP1: a DSB escort
作者
关键词
-
出版物
GENES & DEVELOPMENT
Volume 34, Issue 1-2, Pages 7-23
出版商
Cold Spring Harbor Laboratory
发表日期
2020-01-03
DOI
10.1101/gad.333237.119
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Advances in understanding DNA processing and protection at stalled replication forks
- (2019) Kimberly Rickman et al. JOURNAL OF CELL BIOLOGY
- H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids
- (2019) Kyosuke Nakamura et al. NATURE CELL BIOLOGY
- NBS1 promotes the endonuclease activity of the MRE11‐RAD50 complex by sensing CtIP phosphorylation
- (2019) Roopesh Anand et al. EMBO JOURNAL
- PARP Inhibitors: Extending Benefit Beyond BRCA-Mutant Cancers
- (2019) Patrick G. Pilié et al. CLINICAL CANCER RESEARCH
- RPA Phosphorylation Inhibits DNA Resection
- (2019) Michael M. Soniat et al. MOLECULAR CELL
- Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments
- (2019) Sinan Kilic et al. EMBO JOURNAL
- 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function
- (2019) Devakumar Sundaravinayagam et al. Cell Reports
- 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
- (2019) Elsa Callen et al. MOLECULAR CELL
- Stabilization of chromatin topology safeguards genome integrity
- (2019) Fena Ochs et al. NATURE
- DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
- (2018) Rajat Gupta et al. CELL
- H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2
- (2018) Marco Simonetta et al. CELL CYCLE
- Homologous recombination and the repair of DNA double-strand breaks
- (2018) William Douglass Wright et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Initial Response of a Eukaryotic Replisome to DNA Damage
- (2018) Martin R.G. Taylor et al. MOLECULAR CELL
- MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining
- (2018) Putzer J. Hung et al. MOLECULAR CELL
- Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
- (2018) Harveer Dev et al. NATURE CELL BIOLOGY
- Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein
- (2018) Maria Victoria Botuyan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR
- (2018) Yaxin Dai et al. Nature Communications
- Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein
- (2018) Maria Victoria Botuyan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells
- (2018) Marco Barazas et al. Cell Reports
- Shelterin-Mediated Telomere Protection
- (2018) Titia de Lange Annual Review of Genetics
- SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice
- (2018) Steven Findlay et al. EMBO JOURNAL
- Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1b
- (2018) Katja Kratz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
- (2018) Michal Zimmermann et al. NATURE
- 53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
- (2018) Hind Ghezraoui et al. NATURE
- The shieldin complex mediates 53BP1-dependent DNA repair
- (2018) Sylvie M. Noordermeer et al. NATURE
- 53BP1–RIF1–shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
- (2018) Zachary Mirman et al. NATURE
- An OB-fold complex controls the repair pathways for DNA double-strand breaks
- (2018) Shengxian Gao et al. Nature Communications
- DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
- (2018) Yizhou Joseph He et al. NATURE
- The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
- (2018) Jordan R. Becker et al. Nature Communications
- PHF11 promotes DSB resection, ATR signaling, and HR
- (2017) Yi Gong et al. GENES & DEVELOPMENT
- The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompaction
- (2017) Leonid A. Timashev et al. GENES & DEVELOPMENT
- The p53-binding protein 1-Tudor-interacting repair regulator complex participates in the DNA damage response
- (2017) Aili Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nonhomologous DNA end-joining for repair of DNA double-strand breaks
- (2017) Nicholas R. Pannunzio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair
- (2017) Logan R. Myler et al. MOLECULAR CELL
- Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
- (2017) Angelo Taglialatela et al. MOLECULAR CELL
- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
- (2017) Nausica Arnoult et al. NATURE
- TIRR regulates 53BP1 by masking its histone methyl-lysine binding function
- (2017) Pascal Drané et al. NATURE
- The control of DNA repair by the cell cycle
- (2017) Nicole Hustedt et al. NATURE CELL BIOLOGY
- The essential kinase ATR: ensuring faithful duplication of a challenging genome
- (2017) Joshua C. Saldivar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The multifaceted roles of PARP1 in DNA repair and chromatin remodelling
- (2017) Arnab Ray Chaudhuri et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1
- (2017) Swapna Ganduri et al. NUCLEIC ACIDS RESEARCH
- Dynamic DNA binding, junction recognition and G4 melting activity underlie the telomeric and genome-wide roles of human CST
- (2017) Anukana Bhattacharjee et al. NUCLEIC ACIDS RESEARCH
- Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells
- (2017) Pepijn M. Schoonen et al. Nature Communications
- Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin
- (2017) Stefania Pellegrino et al. Cell Reports
- 53BP1 and BRCA1 control pathway choice for stalled replication restart
- (2017) Yixi Xu et al. eLife
- A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plus
- (2016) Hiroyuki Takai et al. GENES & DEVELOPMENT
- Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts
- (2016) Rajashree A. Deshpande et al. MOLECULAR CELL
- 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms
- (2016) Raquel Cuella-Martin et al. MOLECULAR CELL
- Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection
- (2016) Roopesh Anand et al. MOLECULAR CELL
- H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex
- (2016) Giulia Saredi et al. NATURE
- Replication fork stability confers chemoresistance in BRCA-deficient cells
- (2016) Arnab Ray Chaudhuri et al. NATURE
- 53BP1 fosters fidelity of homology-directed DNA repair
- (2016) Fena Ochs et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination
- (2016) Stephanie Bregenhorn et al. NUCLEIC ACIDS RESEARCH
- Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins
- (2016) Logan R. Myler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action
- (2016) Y. Pommier et al. Science Translational Medicine
- The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins
- (2016) Gabrielle J. Grundy et al. Nature Communications
- 53BP1 fosters fidelity of homology-directed DNA repair
- (2016) Fena Ochs et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- 53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair
- (2015) Francisca Lottersberger et al. CELL
- MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
- (2015) Vera Boersma et al. NATURE
- A mechanism for the suppression of homologous recombination in G1 cells
- (2015) Alexandre Orthwein et al. NATURE
- REV7 counteracts DNA double-strand break resection and affects PARP inhibition
- (2015) Guotai Xu et al. NATURE
- Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response
- (2015) Ralph E Kleiner et al. Nature Chemical Biology
- Control of telomerase action at human telomeres
- (2015) Dirk Hockemeyer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?
- (2015) Agnel Sfeir et al. TRENDS IN BIOCHEMICAL SCIENCES
- Control of telomerase action at human telomeres
- (2015) Dirk Hockemeyer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- PTIP associates with Artemis to dictate DNA repair pathway choice
- (2014) Jiadong Wang et al. GENES & DEVELOPMENT
- Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation
- (2013) Ylli Doksani et al. CELL
- 53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions
- (2013) Elsa Callen et al. CELL
- RIF1 Counteracts BRCA1-mediated End Resection during DNA Repair
- (2013) Lin Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
- (2013) J. Ross Chapman et al. MOLECULAR CELL
- A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
- (2013) Cristina Escribano-Díaz et al. MOLECULAR CELL
- 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
- (2013) Amélie Fradet-Turcotte et al. NATURE
- Push back to respond better: regulatory inhibition of the DNA double-strand break response
- (2013) Stephanie Panier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Double-strand break repair: 53BP1 comes into focus
- (2013) Stephanie Panier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Role of 53BP1 oligomerization in regulating double-strand break repair
- (2013) F. Lottersberger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection
- (2013) M. Zimmermann et al. SCIENCE
- Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
- (2013) M. Di Virgilio et al. SCIENCE
- 53BP1: pro choice in DNA repair
- (2013) Michal Zimmermann et al. TRENDS IN CELL BIOLOGY
- A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
- (2012) Katharina Schlacher et al. CANCER CELL
- RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
- (2012) Francesca Mattiroli et al. CELL
- Telomeric 3′ Overhangs Derive from Resection by Exo1 and Apollo and Fill-In by POT1b-Associated CST
- (2012) Peng Wu et al. CELL
- The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1
- (2012) Soo-Hyun Yang et al. EMBO JOURNAL
- BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
- (2012) J. R. Chapman et al. JOURNAL OF CELL SCIENCE
- The human CST complex is a terminator of telomerase activity
- (2012) Liuh-Yow Chen et al. NATURE
- Double-Strand Break End Resection and Repair Pathway Choice
- (2011) Lorraine S. Symington et al. Annual Review of Genetics
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
- (2011) Katharina Schlacher et al. CELL
- The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates
- (2011) Uttiya Basu et al. CELL
- BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
- (2011) A. V. Nimonkar et al. GENES & DEVELOPMENT
- Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1
- (2011) Anne Bothmer et al. MOLECULAR CELL
- Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
- (2011) Valerie Garcia et al. NATURE
- DNA-damage response and repair activities at uncapped telomeres depend on RNF8
- (2011) Marieke H. Peuscher et al. NATURE CELL BIOLOGY
- 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
- (2010) Samuel F. Bunting et al. CELL
- Evolution of CST function in telomere maintenance
- (2010) Carolyn Price et al. CELL CYCLE
- SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair
- (2010) Yung C Lam et al. EMBO JOURNAL
- 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
- (2010) Anne Bothmer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
- (2010) Andrew Tutt et al. LANCET
- Apollo Contributes to G Overhang Maintenance and Protects Leading-End Telomeres
- (2010) Peng Wu et al. MOLECULAR CELL
- 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
- (2010) Angela T. Noon et al. NATURE CELL BIOLOGY
- Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks
- (2010) Matthew L Nicolette et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
- (2010) Peter Bouwman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
- (2009) Carsten Doil et al. CELL
- The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
- (2009) Grant S. Stewart et al. CELL
- A DNA Polymerase-α·Primase Cofactor with Homology to Replication Protein A-32 Regulates DNA Replication in Mammalian Cells
- (2009) Darren E. Casteel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
- (2009) Pablo Huertas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Mre11 Complex and the Response to Dysfunctional Telomeres
- (2009) C. L. Attwooll et al. MOLECULAR AND CELLULAR BIOLOGY
- Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2
- (2009) N. Dimitrova et al. MOLECULAR AND CELLULAR BIOLOGY
- Conserved Telomere Maintenance Component 1 Interacts with STN1 and Maintains Chromosome Ends in Higher Eukaryotes
- (2009) Yulia V. Surovtseva et al. MOLECULAR CELL
- Multiple roles for MRE11 at uncapped telomeres
- (2009) Yibin Deng et al. NATURE
- Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers
- (2009) Peter C. Fong et al. NEW ENGLAND JOURNAL OF MEDICINE
- An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks
- (2008) O. Zgheib et al. MOLECULAR AND CELLULAR BIOLOGY
- 53BP1 facilitates long-range DNA end-joining during V(D)J recombination
- (2008) Simone Difilippantonio et al. NATURE
- 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
- (2008) Nadya Dimitrova et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now