L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage

USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response

(2016) Zhiquan Wang et al.   GENES & DEVELOPMENT

Deubiquitination and Activation of AMPK by USP10

(2016) Min Deng et al.   MOLECULAR CELL

Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

(2016) Petra Schwertman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation

(2015) Hilmar Strickfaden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

(2015) Tina Thorslund et al.   NATURE

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Chromatin Remodeling at DNA Double-Strand Breaks

(2013) Brendan D. Price et al.   CELL

RNF168 forms a functional complex with RAD6 during the DNA damage response

(2013) C. Liu et al.   JOURNAL OF CELL SCIENCE

SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes

(2013) C. Stielow et al.   NUCLEIC ACIDS RESEARCH

Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68

(2012) Hsin-Hui Wu et al.   BIOCHEMISTRY

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

The Polycomb Group Protein L3mbtl2 Assembles an Atypical PRC1-Family Complex that Is Essential in Pluripotent Stem Cells and Early Development

(2012) Jinzhong Qin et al.   Cell Stem Cell

The Histone Methyltransferase MMSET Regulates Class Switch Recombination

(2012) H. Pei et al.   JOURNAL OF IMMUNOLOGY

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain

(2012) Jinping Liu et al.   NUCLEIC ACIDS RESEARCH

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

(2011) Simon Bekker-Jensen et al.   FEBS LETTERS

Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability

(2011) Masakazu Hamada et al.   JOURNAL OF CELL BIOLOGY

L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure

(2011) Patrick Trojer et al.   MOLECULAR CELL

DNA-damage response and repair activities at uncapped telomeres depend on RNF8

(2011) Marieke H. Peuscher et al.   NATURE CELL BIOLOGY

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

(2011) Klara Acs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone deacetylase 3 is selectively involved in L3MBTL2-mediated transcriptional repression

(2010) Jung-Yoon Yoo et al.   FEBS LETTERS

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability

(2010) N. Gurvich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Multiple roles for MRE11 at uncapped telomeres

(2009) Yibin Deng et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2

(2009) Yahong Guo et al.   NUCLEIC ACIDS RESEARCH

The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination

(2009) S. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA