A Novel Cecropin-LL37 Hybrid Peptide Protects Mice Against EHEC Infection-Mediated Changes in Gut Microbiota, Intestinal Inflammation, and Impairment of Mucosal Barrier Functions

Microbial network disturbances in relapsing refractory Crohn’s disease

(2019) Bahtiyar Yilmaz et al.   NATURE MEDICINE

Microbial genes and pathways in inflammatory bowel disease

(2019) Melanie Schirmer et al.   NATURE REVIEWS MICROBIOLOGY

Cathelicidin- derived PR39 protects enterohemorrhagic Escherichia coli O157:H7 challenged mice by improving epithelial function and balancing the microbiota in the intestine

(2019) Zhang Haiwen et al.   Scientific Reports

Expression and Purification of Hybrid LL-37Tα1 Peptide in Pichia pastoris and Evaluation of Its Immunomodulatory and Anti-inflammatory Activities by LPS Neutralization

(2019) Baseer Ahmad et al.   Frontiers in Immunology

A Novel Peptide Ameliorates LPS-Induced Intestinal Inflammation and Mucosal Barrier Damage via Its Antioxidant and Antiendotoxin Effects

(2019) Lulu Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design and Development of a Novel Peptide for Treating Intestinal Inflammation

(2019) Lulu Zhang et al.   Frontiers in Immunology

Blend of organic acids and medium chain fatty acids prevents the inflammatory response and intestinal barrier dysfunction in mice challenged with enterohemorrhagic Escherichia coli O157:H7

(2018) Jun Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation

(2018) Zhao-Hua Shen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pathogenic and non-pathogenic Escherichia coli colonization and host inflammatory response in a defined microbiota mouse model

(2018) Zachary R. Stromberg et al.   Disease Models & Mechanisms

Gut microbes as future therapeutics in treating inflammatory and infectious diseases: Lessons from recent findings

(2018) Suprabhat Mukherjee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Intestinal Anti-Inflammatory Activity of the Aqueous Extract from Ipomoea asarifolia in DNBS-Induced Colitis in Rats

(2018) Valéria da Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

(2018) Arnau Vich Vila et al.   Science Translational Medicine

Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches

(2017) R. Balfour Sartor et al.   GASTROENTEROLOGY

The role of intestinal bacteria in the development and progression of gastrointestinal tract neoplasms

(2017) Kosuke Mima et al.   SURGICAL ONCOLOGY-OXFORD

Microbial community distribution and dominant bacterial species analysis in the bio-electrochemical system treating low concentration cefuroxime

(2016) Zhao Cheng et al.   CHEMICAL ENGINEERING JOURNAL

Glycine Regulates Expression and Distribution of Claudin-7 and ZO-3 Proteins in Intestinal Porcine Epithelial Cells

(2016) Wei Li et al.   JOURNAL OF NUTRITION

The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

(2016) Stephen M. Vindigni et al.   Therapeutic Advances in Gastroenterology

Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks

(2015) Andrey Morgun et al.   GUT

Porcine β-Defensin 2 Attenuates Inflammation and Mucosal Lesions in Dextran Sodium Sulfate–Induced Colitis

(2015) Feifei Han et al.   JOURNAL OF IMMUNOLOGY

Composition and function of the undernourished neonatal mouse intestinal microbiome

(2015) Geoffrey A. Preidis et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Inhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation

(2015) Yue Sun et al.   MEDIATORS OF INFLAMMATION

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Clostridium difficile infection and inflammatory bowel disease

(2015) Camelia Cojocariu et al.   Turkish Journal of Gastroenterology

The influence of enrofloxacin, florfenicol, ceftiofur and E. coli LPS interaction on T and B cells subset in chicks

(2015) Chrząstek Klaudia et al.   VETERINARY RESEARCH COMMUNICATIONS

ANTI-INFLAMMATORY ACTIVITIES OF CECROPIN A AND ITS MECHANISM OF ACTION

(2014) Eunjung Lee et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Ulcerative jejunitis in a child with celiac disease

(2014) Terry Sigman et al.   BMC GASTROENTEROLOGY

Classical and recent advances in the treatment of inflammatory bowel diseases

(2014) H. Sales-Campos et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

A Phylogenomic View of Ecological Specialization in the Lachnospiraceae, a Family of Digestive Tract-Associated Bacteria

(2014) Conor J. Meehan et al.   Genome Biology and Evolution

Amplified origins of antibiotic resistance

(2014) Darren J. Burgess   NATURE REVIEWS GENETICS

Necroptosis Is Active in Children With Inflammatory Bowel Disease and Contributes to Heighten Intestinal Inflammation

(2013) Maria Pierdomenico et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Preclinical Investigations Reveal the Broad-Spectrum Neutralizing Activity of Peptide Pep19-2.5 on Bacterial Pathogenicity Factors

(2013) Lena Heinbockel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Integrated pharmacokinetics/pharmacodynamics parameters-based dosing guidelines of enrofloxacin in grass carp Ctenopharyngodon idella to minimize selection of drug resistance

(2013) Lijuan Xu et al.   BMC Veterinary Research

Penta-O-galloyl-β-D-glucose ameliorates inflammation by inhibiting MyD88/NF-κB and MyD88/MAPK signalling pathways

(2013) Se-Eun Jang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium

(2013) Hao Chen et al.   GUT

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Oral administration of sodium butyrate attenuates inflammation and mucosal lesion in experimental acute ulcerative colitis

(2011) Erica L.M. Vieira et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Klebsiella pneumoniaeincreases the risk of inflammation and colitis in a murine model of intestinal bowel disease

(2011) In-Ah Lee et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Protection of Intestinal Occludin Tight Junction Protein by Dietary Gangliosides in Lipopolysaccharide-induced Acute Inflammation

(2010) Eek J Park et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Erratum: Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

(2010) R Atreya et al.   NATURE MEDICINE

Therapeutic Options to Modulate Barrier Defects in Inflammatory Bowel Disease

(2009) Nina A. Hering et al.   DIGESTIVE DISEASES

Continual monitoring of intraepithelial lymphocyte immunophenotype and clonality is more important than snapshot analysis in the surveillance of refractory coeliac disease

(2009) H Liu et al.   GUT

Host immune response to antibiotic perturbation of the microbiota

(2009) M Wlodarska et al.   Mucosal Immunology

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Lactobacillus rhamnosus Strain GG Prevents Enterohemorrhagic Escherichia coli O157:H7-Induced Changes in Epithelial Barrier Function

(2008) K. C. Johnson-Henry et al.   INFECTION AND IMMUNITY

Tetrandrine ameliorates dextran-sulfate-sodium-induced colitis in mice through inhibition of nuclear factor -κB activation

(2008) Dei Kui Zhang et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Acute and chronic responses associated with adrenomedullin administration in experimental colitis

(2008) E. Talero et al.   PEPTIDES