The Effects of Alpha-Linolenic Acid on the Secretory Activity of Astrocytes and β Amyloid-Associated Neurodegeneration in Differentiated SH-SY5Y Cells: Alpha-Linolenic Acid Protects the SH-SY5Y cells against β Amyloid Toxicity

In vitro evaluation of the protective effects of plant extracts against amyloid-beta peptide-induced toxicity in human neuroblastoma SH-SY5Y cells

(2019) Ana Luiza Sereia et al.   PLoS One

A fast and simple fluorometric method to detect cell death in 3D intestinal organoids

(2019) Konstantin J Bode et al.   BIOTECHNIQUES

Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity

(2019) Wei Chen et al.   Frontiers in Cellular Neuroscience

Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy

(2018) Anna Jaśkiewicz et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial Dysfunction and Mitophagy Defect Triggered by Heterozygous GBA Mutations

(2018) Hongyu Li et al.   Autophagy

Amyloid-β and Tau Pathology of Alzheimer's Disease Induced by Diabetes in a Rabbit Animal Model

(2018) Claudine L. Bitel et al.   JOURNAL OF ALZHEIMERS DISEASE

Insulin-like growth factor-1 protects SH-SY5Y cells against β-amyloid-induced apoptosis via the PI3K/Akt-Nrf2 pathway

(2017) Zigao Wang et al.   EXPERIMENTAL GERONTOLOGY

Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers

(2017) Jason Pitt et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin expression in cultured astrocytes and the decrease by amyloid β

(2017) Katsura Takano et al.   NEUROCHEMISTRY INTERNATIONAL

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Ratiometric analysis of Acridine Orange staining in the study of acidic organelles and autophagy

(2016) Marcos P. Thomé et al.   JOURNAL OF CELL SCIENCE

Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line

(2016) Mackenzie M. Shipley et al.   Jove-Journal of Visualized Experiments

Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains

(2015) Xuan Ye et al.   HUMAN MOLECULAR GENETICS

Long-Term Dietary Alpha-Linolenic Acid Supplement Alleviates Cognitive Impairment Correlate with Activating Hippocampal CREB Signaling in Natural Aging Rats

(2015) Hui Gao et al.   MOLECULAR NEUROBIOLOGY

Mechanisms of Mitochondrial Dysfunction in Alzheimer’s Disease

(2015) Chris Cadonic et al.   MOLECULAR NEUROBIOLOGY

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

(2014) Michela Guglielmotto et al.   Autophagy

Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling

(2014) Luan Pereira Diniz et al.   GLIA

Apoptosis in Alzheimer’s Disease: An Understanding of the Physiology, Pathology and Therapeutic Avenues

(2014) M. Obulesu et al.   NEUROCHEMICAL RESEARCH

Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

(2014) A. J. Westwood et al.   NEUROLOGY

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease

(2014) M-S Tan et al.   Cell Death & Disease

Dose-dependent folic acid and memantine treatments promote synergistic or additive protection against Aβ(25–35) peptide-induced apoptosis in SH-SY5Y cells mediated by mitochondria stress-associated death signals

(2013) Ta-Fu Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons

(2013) G. Amadoro et al.   NEUROBIOLOGY OF DISEASE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mitochondrial dynamics in neurodegeneration

(2012) Kie Itoh et al.   TRENDS IN CELL BIOLOGY

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

(2011) M. J. Calkins et al.   HUMAN MOLECULAR GENETICS

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

(2011) Saori R. Yoshii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

(2011) Baiyang Sheng et al.   JOURNAL OF NEUROCHEMISTRY

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

(2010) Sumihiro Kawajiri et al.   FEBS LETTERS

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases

(2009) Gary E. Gibson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dietary supplementation of alpha-linolenic acid in an enriched rapeseed oil diet protects from stroke

(2009) C. Nguemeni et al.   PHARMACOLOGICAL RESEARCH

DHA Hydroperoxides as a Potential Inducer of Neuronal Cell Death: a Mitochondrial Dysfunction-Mediated Pathway

(2008) Xuebo Liu et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Amyloid-  overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

(2008) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA