标题
Regulation of Wnt Signaling through Ubiquitination and Deubiquitination in Cancers
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 11, Pages 3904
出版商
MDPI AG
发表日期
2020-06-02
DOI
10.3390/ijms21113904
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Proteogenomic Characterization of Endometrial Carcinoma
- (2020) Yongchao Dou et al. CELL
- Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex
- (2020) Youn-Sang Jung et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth
- (2020) Xue Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers
- (2020) Shan Li et al. ONCOGENE
- Wnt3a Stimulation Promotes Primary Ciliogenesis through β-Catenin Phosphorylation-Induced Reorganization of Centriolar Satellites
- (2020) Mi-Lang Kyun et al. Cell Reports
- USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating the Wnt/β‐catenin pathway via Axin1 deubiquitination
- (2020) Tong Huang et al. CELL BIOLOGY INTERNATIONAL
- Proteomics analysis reveals the role of ubiquitin specific protease (USP47) in Epithelial to Mesenchymal Transition (EMT) induced by TGFβ2 in breast cells
- (2020) Virgínia Campos Silvestrini et al. Journal of Proteomics
- Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells
- (2019) Nicola Fenderico et al. Nature Communications
- The Roles of Low-Density Lipoprotein Receptor-Related Proteins 5, 6, and 8 in Cancer: A Review
- (2019) Zulaika Roslan et al. Journal of Oncology
- Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15
- (2019) Joan Teyra et al. STRUCTURE
- Interplay between the Endogenous Opioid System and Proteasome Complex: Beyond Signaling
- (2019) Francesca Caputi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tre2 (USP6NL) promotes colorectal cancer cell proliferation via Wnt/β-catenin pathway
- (2019) Kang Sun et al. Cancer Cell International
- Association between AXIN1 Gene Polymorphisms and Bladder Cancer in Chinese Han Population
- (2019) Qin Li et al. DISEASE MARKERS
- USP7: Structure, substrate specificity, and inhibition
- (2019) Alexandra Pozhidaeva et al. DNA REPAIR
- USP9X-mediated deubiquitination of B cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis
- (2019) Zesen Shang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling
- (2019) Adnan Shami Shah et al. Cell Reports
- USP7: Novel Drug Target in Cancer Therapy
- (2019) Zhiru Wang et al. Frontiers in Pharmacology
- Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines
- (2019) Michał Otręba et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Structural basis for adenylation and thioester bond formation in the ubiquitin E1
- (2019) Zachary S. Hann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Role for the WNT Co-Receptor LRP6 in Pathogenesis and Therapy of Epithelial Cancers
- (2019) Raisch et al. Cancers
- WNT Signaling in Disease
- (2019) Ng et al. Cells
- β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation
- (2019) Dongping Wang et al. Cancer Cell International
- The Regulation of Bone Metabolism and Disorders by Wnt Signaling
- (2019) Kazuhiro Maeda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma
- (2019) Liling Jiang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors
- (2019) Nathan J. Schauer et al. JOURNAL OF MEDICINAL CHEMISTRY
- Wnt signaling and drug resistance in cancer
- (2019) Zheng Zhong et al. MOLECULAR PHARMACOLOGY
- The role of deubiquitinating enzymes in gastric cancer (Review)
- (2019) Jiangang Sun et al. Oncology Letters
- USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin
- (2019) Lei Ji et al. Nature Communications
- Ubiquitin Ligases Involved in the Regulation of Wnt, TGF-β, and Notch Signaling Pathways and Their Roles in Mouse Development and Homeostasis
- (2019) Nikol Baloghova et al. Genes
- β-TRCP-mediated AEBP2 ubiquitination and destruction controls cisplatin resistance in ovarian cancer
- (2019) Qin zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling
- (2019) Satoshi Yamanaka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Recurrent and novel USP6 fusions in cranial fasciitis identified by targeted RNA sequencing
- (2019) Vera A. Paulson et al. MODERN PATHOLOGY
- Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
- (2019) Vu Hong Loan Nguyen et al. Journal of Ovarian Research
- The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis
- (2019) Jianghua Tu et al. Scientific Reports
- The function and regulation of OTU deubiquitinases
- (2019) Jiansen Du et al. Frontiers of Medicine
- RORα Suppresses Epithelial-to-Mesenchymal Transition and Invasion in Human Gastric Cancer Cells via the Wnt/β-Catenin Pathway
- (2019) Jian Su et al. Frontiers in Oncology
- Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1
- (2018) Hyeyoon Lee et al. DEVELOPMENT
- Wnt signaling in development and tissue homeostasis
- (2018) Zachary Steinhart et al. DEVELOPMENT
- Notum attenuates Wnt/β–catenin signaling to promote tracheal cartilage patterning
- (2018) Bradley Gerhardt et al. DEVELOPMENTAL BIOLOGY
- Deubiquitinase inhibitor b-AP15 activates endoplasmic reticulum (ER) stress and inhibits Wnt/Notch1 signaling pathway leading to the reduction of cell survival in hepatocellular carcinoma cells
- (2018) Youming Ding et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- MCPIP3 as a Potential Metastasis Suppressor Gene in Human Colorectal Cancer
- (2018) Fat-Moon Suk et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Frizzled Receptors as Potential Therapeutic Targets in Human Cancers
- (2018) Chui-Mian Zeng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
- (2018) Dominika Kwasna et al. MOLECULAR CELL
- ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability
- (2018) Peter Haahr et al. MOLECULAR CELL
- Impaired Wnt Signaling in the Prefrontal Cortex of Alzheimer’s Disease
- (2018) Jonas Folke et al. MOLECULAR NEUROBIOLOGY
- The interplay of Canonical and Non-canonical Wnt Signaling in Metabolic Syndrome
- (2018) Maen D. Abou Ziki et al. NUTRITION RESEARCH
- Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling
- (2018) Hae-Kyung Lee et al. ONCOGENE
- A family of unconventional deubiquitinases with modular chain specificity determinants
- (2018) Thomas Hermanns et al. Nature Communications
- S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer
- (2018) Yumei Huang et al. Theranostics
- ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling
- (2018) Vincent C. Pai et al. ONCOGENE
- WNT Signaling in Cancer Immunosurveillance
- (2018) Lorenzo Galluzzi et al. TRENDS IN CELL BIOLOGY
- Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy
- (2018) Tao Yuan et al. Frontiers in Pharmacology
- TCF/LEF dependent and independent transcriptional regulation of Wnt/β‐catenin target genes
- (2018) Nikolaos Doumpas et al. EMBO JOURNAL
- USP25 regulates Wnt signaling by controlling the stability of tankyrases
- (2017) Daichao Xu et al. GENES & DEVELOPMENT
- An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons
- (2017) Monica Boselli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein
- (2017) Lisheng Li et al. MOLECULAR AND CELLULAR BIOLOGY
- Deubiquitylating enzymes and drug discovery: emerging opportunities
- (2017) Jeanine A. Harrigan et al. NATURE REVIEWS DRUG DISCOVERY
- Functional significance and therapeutic implication of ring-type E3 ligases in colorectal cancer
- (2017) L Liu et al. ONCOGENE
- The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy
- (2017) Yong Tae Kwon et al. TRENDS IN BIOCHEMICAL SCIENCES
- The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor
- (2017) Jie Xu et al. Nature Communications
- The regulation of β-catenin activity and function in cancer: therapeutic opportunities
- (2017) Shuang Shang et al. Oncotarget
- The B-box module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization
- (2017) Songbo Xie et al. Oncotarget
- FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma
- (2017) Ting-Ting Cao et al. Oncotarget
- USP7 Is a Tumor-Specific WNT Activator for APC -Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination
- (2017) Laura Novellasdemunt et al. Cell Reports
- Membrane-bound β-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells
- (2017) L Das et al. Oncogenesis
- Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling
- (2017) Wonhee Han et al. Scientific Reports
- Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy
- (2016) Takahiro Domoto et al. CANCER SCIENCE
- Ubiquitin modifications
- (2016) Kirby N Swatek et al. CELL RESEARCH
- The emerging complexity of ubiquitin architecture
- (2016) Fumiaki Ohtake et al. JOURNAL OF BIOCHEMISTRY
- Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models
- (2016) Mindy I. Davis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes
- (2016) Syed Arif Abdul Rehman et al. MOLECULAR CELL
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds
- (2016) Babita Madan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6
- (2016) Elsa Perrody et al. eLife
- The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
- (2016) Bharathi Suresh et al. Stem Cells International
- Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer
- (2016) Huai-Xiang Hao et al. Cancers
- The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells
- (2016) Xin Wang et al. Scientific Reports
- Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting
- (2015) Christoph H. Emmerich et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Deubiquitinases (DUBs) and DUB inhibitors: a patent review
- (2015) Pershang Farshi et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Deubiquitinating enzymes in cellular signaling and disease regulation
- (2015) Pranita Hanpude et al. IUBMB LIFE
- The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer
- (2015) Salima Daou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Roles of transcriptional factor 7 in production of inflammatory factors for lung diseases
- (2015) Yichun Zhu et al. Journal of Translational Medicine
- Dishevelled Promotes Wnt Receptor Degradation through Recruitment of ZNRF3/RNF43 E3 Ubiquitin Ligases
- (2015) Xiaomo Jiang et al. MOLECULAR CELL
- Ubiquitin specific protease 4 positively regulates the WNT/β-catenin signaling in colorectal cancer
- (2015) Sun-Il Yun et al. Molecular Oncology
- Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
- (2015) Jan Krönke et al. NATURE
- The unravelling of the ubiquitin system
- (2015) Aaron Ciechanover NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ZNRF3/RNF43 – A direct linkage of extracellular recognition and E3 ligase activity to modulate cell surface signalling
- (2015) Matthias Zebisch et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane
- (2015) Anke Loregger et al. Science Signaling
- The demographics of the ubiquitin system
- (2015) Michael J. Clague et al. TRENDS IN CELL BIOLOGY
- Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production
- (2015) Ryeojin Ko et al. Nature Communications
- The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane
- (2015) Anke Loregger et al. Science Signaling
- GSK-3 as potential target for therapeutic intervention in cancer
- (2015) James A. McCubrey et al. Oncotarget
- Cellular ubiquitin pool dynamics and homeostasis
- (2014) Chul-Woo Park et al. BMB Reports
- The cellular story of dishevelleds
- (2014) Anja Kafka et al. CROATIAN MEDICAL JOURNAL
- Molecular functions of the TLE tetramerization domain in Wnt target gene repression
- (2014) J. V. Chodaparambil et al. EMBO JOURNAL
- RBR E3-ligases at work
- (2014) J. J. Smit et al. EMBO REPORTS
- Epigenetic inactivation of the candidate tumor suppressorUSP44is a frequent and early event in colorectal neoplasia
- (2014) Mathew A Sloane et al. Epigenetics
- AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions
- (2014) Teresa M. Ribeiro-Rodrigues et al. FASEB JOURNAL
- The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
- (2014) W. de Lau et al. GENES & DEVELOPMENT
- The Ubiquitin Ligase RNF220 Enhances Canonical Wnt Signaling through USP7-Mediated Deubiquitination of -Catenin
- (2014) P. Ma et al. MOLECULAR AND CELLULAR BIOLOGY
- Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis
- (2014) Birgit Schittek et al. Molecular Cancer
- Huwe1-Mediated Ubiquitylation of Dishevelled Defines a Negative Feedback Loop in the Wnt Signaling Pathway
- (2014) R. E. A. de Groot et al. Science Signaling
- Wnt signaling in the nervous system and in Alzheimer's disease
- (2014) N. C. Inestrosa et al. Journal of Molecular Cell Biology
- Regulation of Wnt/β-catenin signaling by posttranslational modifications
- (2014) Chenxi Gao et al. Cell and Bioscience
- Regulation of proteolysis by human deubiquitinating enzymes
- (2013) Ziad M. Eletr et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Intracellular protein degradation: From a vague idea through the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting
- (2013) Aaron Ciechanover BIOORGANIC & MEDICINAL CHEMISTRY
- Vialinin A is a ubiquitin-specific peptidase inhibitor
- (2013) Kiyoshi Okada et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Axin gene methylation status correlates with radiosensitivity of lung cancer cells
- (2013) Lian-He Yang et al. BMC CANCER
- OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
- (2013) Tycho E.T. Mevissen et al. CELL
- The role of the ubiquitin proteasome system in lymphoma
- (2013) K. Stephen Suh et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Lipid modification in Wnt structure and function
- (2013) Jiyuan Ke et al. CURRENT OPINION IN LIPIDOLOGY
- The Wnt/β-catenin pathway in ovarian cancer: A review
- (2013) Rebecca C. Arend et al. GYNECOLOGIC ONCOLOGY
- Ubiquitin-interacting Motifs Confer Full Catalytic Activity, but Not Ubiquitin Chain Substrate Specificity, to Deubiquitinating Enzyme USP37
- (2013) Hidetaka Tanno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein Kinase PKN1 Represses Wnt/β-Catenin Signaling in Human Melanoma Cells
- (2013) Richard G. James et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HECT Domain-containing E3 Ubiquitin Ligase NEDD4L Negatively Regulates Wnt Signaling by Targeting Dishevelled for Proteasomal Degradation
- (2013) Yi Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- JosD1, a Membrane-targeted Deubiquitinating Enzyme, Is Activated by Ubiquitination and Regulates Membrane Dynamics, Cell Motility, and Endocytosis
- (2013) Takahiro Seki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
- (2013) H Jung et al. Oncogenesis
- Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex
- (2012) Vivian S.W. Li et al. CELL
- Role of CSN5/JAB1 in Wnt/β-catenin activation in colorectal cancer cells
- (2012) Anke K. Schütz et al. FEBS LETTERS
- Precise Regulation of Porcupine Activity Is Required for Physiological Wnt Signaling
- (2012) Kyle D. Proffitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Malin Regulates Wnt Signaling Pathway through Degradation of Dishevelled2
- (2012) Jaiprakash Sharma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HECT and RING finger families of E3 ubiquitin ligases at a glance
- (2012) M. B. Metzger et al. JOURNAL OF CELL SCIENCE
- The E3 Ubiquitin Ligase ITCH Negatively Regulates Canonical Wnt Signaling by Targeting Dishevelled Protein
- (2012) W. Wei et al. MOLECULAR AND CELLULAR BIOLOGY
- The Ubiquitin-Proteasome System Meets Angiogenesis
- (2012) N. Rahimi MOLECULAR CANCER THERAPEUTICS
- The complex world of WNT receptor signalling
- (2012) Christof Niehrs NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Wnt/ -Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma
- (2012) T. L. Biechele et al. Science Signaling
- Targeted Disruption of the BCL9/ -Catenin Complex Inhibits Oncogenic Wnt Signaling
- (2012) K. Takada et al. Science Translational Medicine
- Wnt Proteins
- (2012) K. Willert et al. Cold Spring Harbor Perspectives in Biology
- Wnt Signaling in Skin Development, Homeostasis, and Disease
- (2012) X. Lim et al. Cold Spring Harbor Perspectives in Biology
- Wnt Signaling in Bone Development and Disease: Making Stronger Bone with Wnts
- (2012) J. B. Regard et al. Cold Spring Harbor Perspectives in Biology
- TCF/LEFs and Wnt Signaling in the Nucleus
- (2012) K. M. Cadigan et al. Cold Spring Harbor Perspectives in Biology
- The -Catenin Destruction Complex
- (2012) J. L. Stamos et al. Cold Spring Harbor Perspectives in Biology
- The Wnt pathway destabilizes adherens junctions and promotes cell migration via β-catenin and its target gene cyclin D1
- (2012) Annica Vlad-Fiegen et al. FEBS Open Bio
- K63-Linked Ubiquitination in Kinase Activation and Cancer
- (2012) Guocan Wang et al. Frontiers in Oncology
- Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells
- (2011) Orkhontuya Tsedensodnom et al. EXPERIMENTAL CELL RESEARCH
- Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes
- (2011) Martin Sadowski et al. IUBMB LIFE
- The Ubiquitin-Specific Protease USP34 Regulates Axin Stability and Wnt/ -Catenin Signaling
- (2011) T. T. H. Lui et al. MOLECULAR AND CELLULAR BIOLOGY
- Deubiquitinases in cancer: new functions and therapeutic options
- (2011) J M Fraile et al. ONCOGENE
- Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis
- (2010) V. Kapuria et al. CANCER RESEARCH
- The various roles of ubiquitin in Wnt pathway regulation
- (2010) Daniele V. F. Tauriello et al. CELL CYCLE
- Direct Ubiquitination of β-Catenin by Siah-1 and Regulation by the Exchange Factor TBL1
- (2010) Yoana N. Dimitrova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reconstitution of a Frizzled8·Wnt3a·LRP6 Signaling Complex Reveals Multiple Wnt and Dkk1 Binding Sites on LRP6
- (2010) Eric Bourhis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling
- (2010) Jian Liang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl
- (2010) Daniele V.F. Tauriello et al. MOLECULAR CELL
- Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
- (2009) Francisca E. Reyes-Turcu et al. Annual Review of Biochemistry
- Dishevelled: The hub of Wnt signaling
- (2009) Chan Gao et al. CELLULAR SIGNALLING
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
- (2009) David Komander et al. EMBO REPORTS
- Wnt signaling as a therapeutic target for bone diseases
- (2009) Luke H Hoeppner et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The COP9 Signalosome Mediates β-Catenin Degradation by Deneddylation and Blocks Adenomatous Polyposis coli Destruction via USP15
- (2009) Xiaohua Huang et al. JOURNAL OF MOLECULAR BIOLOGY
- Strong association between lung cancer and the AXIN2 polymorphism
- (2009) Pinarbasi Molecular Medicine Reports
- Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
- (2009) Shih-Min A. Huang et al. NATURE
- Breaking the chains: structure and function of the deubiquitinases
- (2009) David Komander et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Wnt Signaling in Liver Cancer
- (2008) Yutaka Takigawa et al. CURRENT DRUG TARGETS
- R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism
- (2008) Kyung-Ah Kim et al. MOLECULAR BIOLOGY OF THE CELL
- Classification, Expression Pattern, and E3 Ligase Activity Assay of Rice U-Box-Containing Proteins
- (2008) Li-Rong Zeng et al. Molecular Plant
- Jade-1 inhibits Wnt signalling by ubiquitylating β-catenin and mediates Wnt pathway inhibition by pVHL
- (2008) Vipul C. Chitalia et al. NATURE CELL BIOLOGY
- Ubiquitin dimers control the hydrolase activity of UCH-L3
- (2008) Rieko Setsuie et al. NEUROCHEMISTRY INTERNATIONAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now