The various roles of ubiquitin in Wnt pathway regulation

MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway

(2010) Ser Sue Ng et al.   BIOLOGICAL CHEMISTRY

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

(2010) Akiko Mukai et al.   EMBO JOURNAL

Myristoylated Naked2 Antagonizes Wnt-β-Catenin Activity by Degrading Dishevelled-1 at the Plasma Membrane

(2010) Tianhui Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Ubiquitination of β-Catenin by Siah-1 and Regulation by the Exchange Factor TBL1

(2010) Yoana N. Dimitrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization

(2010) C. Metcalfe et al.   JOURNAL OF CELL SCIENCE

Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl

(2010) Daniele V.F. Tauriello et al.   MOLECULAR CELL

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

(2009) Masahiro Narimatsu et al.   CELL

Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation

(2009) Ping Xu et al.   CELL

Dishevelled: The hub of Wnt signaling

(2009) Chan Gao et al.   CELLULAR SIGNALLING

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc

(2009) Hugh K Arnold et al.   EMBO JOURNAL

Linear polyubiquitination: a new regulator of NF-κB activation

(2009) Kazuhiro Iwai et al.   EMBO REPORTS

The COP9 Signalosome Mediates β-Catenin Degradation by Deneddylation and Blocks Adenomatous Polyposis coli Destruction via USP15

(2009) Xiaohua Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization

(2009) Matias Simons et al.   NATURE CELL BIOLOGY

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin-binding domains — from structures to functions

(2009) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wnt signaling activation and mammary gland hyperplasia in MMTV–LRP6 transgenic mice: implication for breast cancer tumorigenesis

(2009) J Zhang et al.   ONCOGENE

Regulation of ciliary polarity by the APC/C

(2009) A. Ganner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

(2008) Lingyan Jin et al.   CELL

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Ubiquitin in trafficking: The network at work

(2008) Filippo Acconcia et al.   EXPERIMENTAL CELL RESEARCH

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains

(2008) H. Tran et al.   GENES & DEVELOPMENT

The Structure of the CYLD USP Domain Explains Its Specificity for Lys63-Linked Polyubiquitin and Reveals a B Box Module

(2008) David Komander et al.   MOLECULAR CELL

Jade-1 inhibits Wnt signalling by ubiquitylating β-catenin and mediates Wnt pathway inhibition by pVHL

(2008) Vipul C. Chitalia et al.   NATURE CELL BIOLOGY

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

(2008) Wei Li et al.   PLoS One

Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum

(2008) L. Abrami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt3a-Mediated Formation of Phosphatidylinositol 4,5-Bisphosphate Regulates LRP6 Phosphorylation

(2008) W. Pan et al.   SCIENCE

Dual Positive and Negative Regulation of Wingless Signaling by Adenomatous Polyposis Coli

(2008) C. M. Takacs et al.   SCIENCE

Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3

(2007) Yi-Nan Lee et al.   CELLULAR SIGNALLING

Endocytosis: A Positive or a Negative Influence on Wnt Signalling?

(2007) Maria Gagliardi et al.   TRAFFIC