标题
Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology
作者
关键词
-
出版物
Frontiers in Oncology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-04-09
DOI
10.3389/fonc.2020.00476
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Iron as a Central Player and Promising Target in Cancer Progression
- (2019) Michaela Jung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- miR-148a regulates expression of the transferrin receptor 1 in hepatocellular carcinoma
- (2019) Kamesh R. Babu et al. Scientific Reports
- Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways
- (2019) Dongya Jia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of exosomes on pre-metastatic niche formation in tumors
- (2019) Yaxin Guo et al. Molecular Cancer
- Oxidative stress-induced angiogenesis
- (2019) Yu-Jing Huang et al. JOURNAL OF CLINICAL NEUROSCIENCE
- New insights into the links between hypoxia and iron homeostasis
- (2019) Cyril Renassia et al. CURRENT OPINION IN HEMATOLOGY
- Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1α Inhibitor Impairs Pancreatic Tumor Growth
- (2019) Jiayan Lang et al. ACS Nano
- Cancer cells change their glucose metabolism to overcome increased ROS: One step from cancer cell to cancer stem cell?
- (2019) Zahra Ghanbari Movahed et al. BIOMEDICINE & PHARMACOTHERAPY
- Defining the Hallmarks of Metastasis
- (2019) Danny R. Welch et al. CANCER RESEARCH
- MiR-107 function as a tumor suppressor gene in colorectal cancer by targeting transferrin receptor 1
- (2019) Yuxiang Fu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment for Urothelial Cancers in Rats and Dogs
- (2019) Scott J Weir et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
- (2019) Weimin Wang et al. NATURE
- Interactions in the (Pre)metastatic Niche Support Metastasis Formation
- (2019) Ginevra Doglioni et al. Frontiers in Oncology
- Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway
- (2019) Can Cui et al. Cancer Management and Research
- Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation
- (2019) Victor M Corral et al. RNA
- Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11
- (2019) Xueting Lang et al. Cancer Discovery
- The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma
- (2019) Claudia Rehwald et al. BRITISH JOURNAL OF CANCER
- H-Ferritin Affects Cisplatin-Induced Cytotoxicity in Ovarian Cancer Cells through the Modulation of ROS
- (2019) Alessandro Salatino et al. Oxidative Medicine and Cellular Longevity
- Randomized Phase II Trial of Triapine-Cisplatin-Radiotherapy for Locally Advanced Stage Uterine Cervix or Vaginal Cancers
- (2019) Charles A. Kunos et al. Frontiers in Oncology
- Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor-β Signaling in Murine Hepatic Stellate Cells
- (2018) Kosha J. Mehta et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Total RNA extraction from tissues for microRNA and target gene expression analysis: not all kits are created equal
- (2018) Rikki A. M. Brown et al. BMC BIOTECHNOLOGY
- A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies
- (2018) John F. Deeken et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Tumor stressors induce two mechanisms of intracellular P-glycoprotein–mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones
- (2018) Lina Al-Akra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tumor cell expression of CD163 is associated to postoperative radiotherapy and poor prognosis in patients with breast cancer treated with breast-conserving surgery
- (2018) Stina Garvin et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
- (2018) Behrouz Hassannia et al. JOURNAL OF CLINICAL INVESTIGATION
- The iron chelator deferasirox synergizes with chemotherapy to treat triple negative breast cancers
- (2018) Sandrine Tury et al. JOURNAL OF PATHOLOGY
- Mobilization of iron from ferritin: new steps and details
- (2018) A. La et al. Metallomics
- Knockdown of zinc transporter ZIP8 expression inhibits neuroblastoma progression and metastasis in�vitro
- (2018) Zhengrong Mei et al. Molecular Medicine Reports
- Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer
- (2018) Nicole Blanchette-Farra et al. ONCOGENE
- Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3′-IRE stem–loops
- (2018) Masaki Miyazawa et al. RNA
- Role of hepcidin and iron metabolism in the onset of prostate cancer
- (2018) Bin Zhao et al. Oncology Letters
- Association of iron metabolic enzyme hepcidin expression levels with the prognosis of patients with pancreatic cancer
- (2018) Reishi Toshiyama et al. Oncology Letters
- Ferroptosis: A Novel Anti-tumor Action for Cisplatin
- (2018) Jipeng Guo et al. Cancer Research and Treatment
- The Role of Ferroptosis in Cancer Development and Treatment Response
- (2018) Bin Lu et al. Frontiers in Pharmacology
- DMT1 and iron transport
- (2018) Izumi Yanatori et al. FREE RADICAL BIOLOGY AND MEDICINE
- Inhibition of Wnt/β-catenin signaling suppresses myofibroblast differentiation of lung resident mesenchymal stem cells and pulmonary fibrosis
- (2018) Honghui Cao et al. Scientific Reports
- Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/β-catenin pathway in colon cancer cells
- (2018) Zhiqiang Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Metastasis Suppressor, NDRG1, Attenuates Oncogenic TGF-β and NF-ĸB Signaling to Enhance Membrane E-Cadherin Expression in Pancreatic Cancer Cells
- (2018) Sharleen V Menezes et al. CARCINOGENESIS
- A phase I study of the safety and tolerability of VLX600, an Iron Chelator, in patients with refractory advanced solid tumors
- (2018) Kabir Mody et al. INVESTIGATIONAL NEW DRUGS
- Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial
- (2018) Frank Stephen Hodi et al. LANCET ONCOLOGY
- Metastatic growth instructed by neutrophil-derived transferrin
- (2018) Wei Liang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipocalin 2: a potential therapeutic target for breast cancer metastasis
- (2018) Chenxia Hu et al. OncoTargets and Therapy
- Ferritin heavy subunit enhances apoptosis of non-small cell lung cancer cells through modulation of miR-125b/p53 axis
- (2018) Flavia Biamonte et al. Cell Death & Disease
- Ferritin: A potential serum marker for lymph node metastasis in head and neck squamous cell carcinoma
- (2018) Zhangwei Hu et al. Oncology Letters
- Iron in the Tumor Microenvironment—Connecting the Dots
- (2018) Christa Pfeifhofer-Obermair et al. Frontiers in Oncology
- A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma
- (2017) Tasnuva D. Kabir et al. HEPATOLOGY
- Characterization of ferroptosis in murine models of hemochromatosis
- (2017) Hao Wang et al. HEPATOLOGY
- The elemental role of iron in DNA synthesis and repair
- (2017) Sergi Puig et al. Metallomics
- SCARA5 plays a critical role in the progression and metastasis of breast cancer by inactivating the ERK1/2, STAT3, and AKT signaling pathways
- (2017) Kai You et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Fe-S Clusters Emerging as Targets of Therapeutic Drugs
- (2017) Laurence Vernis et al. Oxidative Medicine and Cellular Longevity
- Immunoexpression of lactoferrin in triple-negative breast cancer patients: A proposal to select a less aggressive subgroup
- (2017) Antonio Ieni et al. Oncology Letters
- The Tumor Suppressor, P53, Decreases the Metal Transporter, ZIP14
- (2017) Ningning Zhao et al. Nutrients
- CD163 as a novel target gene of STAT3 is a potential therapeutic target for gastric cancer
- (2017) Zhenguo Cheng et al. Oncotarget
- Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth
- (2017) Zhiyong Deng et al. Oncotarget
- Superior efficacy of the antifungal agent ciclopirox olamine over gemcitabine in pancreatic cancer models
- (2017) Chrysovalantou Mihailidou et al. Oncotarget
- Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment
- (2017) Christina Mertens et al. OncoImmunology
- Melanoma cell expression of macrophage markers in AJCC stage I/II melanoma.
- (2017) T. O. Jensen et al. JOURNAL OF CLINICAL ONCOLOGY
- Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer
- (2017) Avigdor Leftin et al. PLoS One
- Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer
- (2017) Avigdor Leftin et al. Scientific Reports
- The Roles of NRF2 in Modulating Cellular Iron Homeostasis
- (2017) Michael John Kerins et al. ANTIOXIDANTS & REDOX SIGNALING
- Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes
- (2016) Anita CG Chua et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Iron induces cancer stem cells and aggressive phenotypes in human lung cancer cells
- (2016) Pithi Chanvorachote et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Transferrin receptor regulates pancreatic cancer growth by modulating mitochondrial respiration and ROS generation
- (2016) Seung Min Jeong et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Deferasirox, a novel oral iron chelator, shows antiproliferative activity against pancreatic cancer in vitro and in vivo
- (2016) Hirofumi Harima et al. BMC CANCER
- Triapine potentiates platinum-based combination therapy by disruption of homologous recombination repair
- (2016) Elena S Ratner et al. BRITISH JOURNAL OF CANCER
- Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis
- (2016) Xiang Xue et al. Cell Metabolism
- Ferroptosis is an autophagic cell death process
- (2016) Minghui Gao et al. CELL RESEARCH
- Repositioning the Old Fungicide Ciclopirox for New Medical Uses
- (2016) Tao Shen et al. CURRENT PHARMACEUTICAL DESIGN
- Transferrin receptor 1: a target for antibody-mediated cancer therapy
- (2016) Tracy R Daniels-Wells et al. Immunotherapy
- Serum ferritin level is a prognostic marker in patients with peripheral T-cell lymphoma
- (2016) S. Koyama et al. International Journal of Laboratory Hematology
- Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer
- (2016) Seishi Nishitani et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms
- (2016) Zhu-Ling Guo et al. Journal of Hematology & Oncology
- A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models
- (2016) Benjamin Spangler et al. JOURNAL OF MEDICINAL CHEMISTRY
- Lipocalin2 suppresses metastasis of colorectal cancer by attenuating NF-κB-dependent activation of snail and epithelial mesenchymal transition
- (2016) Meibao Feng et al. Molecular Cancer
- Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
- (2016) Saeid Zanganeh et al. Nature Nanotechnology
- A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma
- (2016) Judith G. Villablanca et al. PEDIATRIC BLOOD & CANCER
- Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression
- (2016) Christina Mertens et al. PLoS One
- Lipocalin 2 from macrophages stimulated by tumor cell–derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis
- (2016) Michaela Jung et al. Science Signaling
- Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease
- (2016) Alexander R. Bogdan et al. TRENDS IN BIOCHEMICAL SCIENCES
- Iron chelator-induced apoptosis via the ER stress pathway in gastric cancer cells
- (2016) Jung Lim Kim et al. TUMOR BIOLOGY
- Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma
- (2016) Issei Saeki et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Cancer: fundamentals behind pH targeting and the double-edged approach
- (2016) Tomas Koltai OncoTargets and Therapy
- Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
- (2016) S Ma et al. Cell Death & Disease
- A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC
- (2016) Nicole A Seebacher et al. Cell Death & Disease
- Mitochondria and Iron: current questions
- (2016) Bibbin T. Paul et al. Expert Review of Hematology
- Epigallocatechin Gallate Nanodelivery Systems for Cancer Therapy
- (2016) Andreia Granja et al. Nutrients
- Cell-permeable iron inhibits vascular endothelial growth factor receptor-2 signaling and tumor angiogenesis
- (2016) Devika Kir et al. Oncotarget
- Fusion between cancer cells and macrophages occurs in a murine model of spontaneous neu+ breast cancer without increasing its metastatic potential
- (2016) Michela Lizier et al. Oncotarget
- Serum Ferritin as a Prognostic Biomarker for Survival in Relapsed or Refractory Metastatic Colorectal Cancer
- (2016) Sookyung Lee et al. Journal of Cancer
- Lipocalin 2 from macrophages stimulated by tumor cell–derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis
- (2016) Michaela Jung et al. Science Signaling
- Regulation of the divalent metal ion transporter via membrane budding
- (2016) KimberlyD Mackenzie et al. Cell Discovery
- Iron chelators target both proliferating and quiescent cancer cells
- (2016) Mårten Fryknäs et al. Scientific Reports
- Down-regulation of lipocalin 2 suppresses the growth of human lung adenocarcinoma through oxidative stress involving Nrf2/HO-1 signaling
- (2015) Baoquan Song et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- An important role of the hepcidin–ferroportin signaling in affecting tumor growth and metastasis
- (2015) Wenli Guo et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease
- (2015) D.J.R. Lane et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer
- (2015) Jessica A. Gibbons et al. BMC CANCER
- Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells
- (2015) David L. Schonberg et al. CANCER CELL
- Inhibition of iron uptake by ferristatin II is exerted through internalization of DMT1 at the plasma membrane
- (2015) Izumi Yanatori et al. CELL BIOLOGY INTERNATIONAL
- Body iron status and gastric cancer risk in the EURGAST study
- (2015) Ana Fonseca-Nunes et al. INTERNATIONAL JOURNAL OF CANCER
- miR-20a regulates expression of the iron exporter ferroportin in lung cancer
- (2015) Kamesh R. Babu et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Lipocalin-2 enhances angiogenesis in rat brain endothelial cells via reactive oxygen species and iron-dependent mechanisms
- (2015) Limin Wu et al. JOURNAL OF NEUROCHEMISTRY
- Lactotransferrin expression is downregulated and affects the mitogen-activated protein kinase pathway in gastric cancer
- (2015) GENGQIU LUO et al. Oncology Letters
- Decreased expression of ferroportin in prostate cancer
- (2015) DONG XUE et al. Oncology Letters
- Targeting cancer by binding iron: Dissecting cellular signaling pathways
- (2015) Goldie Y.L. Lui et al. Oncotarget
- MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis
- (2015) Iryna Kindrat et al. Oncotarget
- A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
- (2015) Sanjeev Krishna et al. EBioMedicine
- The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway
- (2015) Jiabei Wang et al. Oncotarget
- Exosomal Tumor MicroRNA Modulates Premetastatic Organ Cells
- (2015) Sanyukta Rana et al. NEOPLASIA
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- The discovery and development of cyclooxygenase-2 inhibitors as potential anticancer therapies
- (2014) Mohsen Vosooghi et al. Expert Opinion on Drug Discovery
- Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis
- (2014) Yatrik M. Shah et al. GASTROENTEROLOGY
- Ferritin Heavy Chain in Triple Negative Breast Cancer: A Favorable Prognostic Marker that Relates to a Cluster of Differentiation 8 Positive (CD8+) Effector T-cell Response
- (2014) Ning Qing Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations
- (2014) Liviu Vanoaica et al. PLoS One
- Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs
- (2014) Eliska Potuckova et al. PLoS One
- Transferrin Receptor 2 Is Frequently and Highly Expressed in Glioblastomas
- (2014) Alessia Calzolari et al. Translational Oncology
- Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments
- (2014) Xiaonan Zhang et al. Nature Communications
- Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
- (2014) Caiguo Zhang et al. Protein & Cell
- The significance of ferritin in cancer: Anti-oxidation, inflammation and tumorigenesis
- (2013) Ahmed A. Alkhateeb et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells
- (2013) K M Dixon et al. BRITISH JOURNAL OF CANCER
- IRP2 Regulates Breast Tumor Growth
- (2013) Wei Wang et al. CANCER RESEARCH
- A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms
- (2013) J. F. Zeidner et al. HAEMATOLOGICA
- A Phase I Dose-Finding Study of Silybin Phosphatidylcholine (Milk Thistle) in Patients With Advanced Hepatocellular Carcinoma
- (2013) Abby B. Siegel et al. INTEGRATIVE CANCER THERAPIES
- Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
- (2013) IGOR P. POGRIBNY et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- PRIMA-1Met/APR-246 Displays High Antitumor Activity in Multiple Myeloma By Induction of p73 and Noxa
- (2013) Manujendra N. Saha et al. MOLECULAR CANCER THERAPEUTICS
- Deferoxamine enhances cell migration and invasion through promotion of HIF-1α expression and epithelial-mesenchymal transition in colorectal cancer
- (2013) WENJING ZHANG et al. ONCOLOGY REPORTS
- Influence of microRNA on the Maintenance of Human Iron Metabolism
- (2013) McKale Davis et al. Nutrients
- Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin
- (2013) Carolyn Sangokoya et al. PLoS Genetics
- Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials
- (2012) Subash C. Gupta et al. AAPS Journal
- Protein degradation and iron homeostasis
- (2012) Joel W. Thompson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Deferasirox (ICL670A) effectively inhibits oesophageal cancer growthin vitroandin vivo
- (2012) SJ Ford et al. BRITISH JOURNAL OF PHARMACOLOGY
- Iron Homeostasis Regulates the Activity of the MicroRNA Pathway through Poly(C)-Binding Protein 2
- (2012) Yujing Li et al. Cell Metabolism
- CCL2 is critical for immunosuppression to promote cancer metastasis
- (2012) Chie Kudo-Saito et al. CLINICAL & EXPERIMENTAL METASTASIS
- The Iron Chelators Dp44mT and DFO Inhibit TGF-β-induced Epithelial-Mesenchymal Transition via Up-Regulation of N-Myc Downstream-regulated Gene 1 (NDRG1)
- (2012) Zhiqiang Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Expression of Deoxyhypusine Hydroxylase (DOHH), the Enzyme That Catalyzes the Activation of eIF5A, by miR-331-3p and miR-642-5p in Prostate Cancer Cells
- (2012) Michael R. Epis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Second-Generation Di-2-Pyridylketone Thiosemicarbazones Show Synergism with Standard Chemotherapeutics and Demonstrate Potent Activity against Lung Cancer Xenografts after Oral and Intravenous Administration in Vivo
- (2012) David B. Lovejoy et al. JOURNAL OF MEDICINAL CHEMISTRY
- STEAP Proteins: From Structure to Applications in Cancer Therapy
- (2012) I. M. Gomes et al. MOLECULAR CANCER RESEARCH
- Ferritin Blocks Inhibitory Effects of Two-Chain High Molecular Weight Kininogen (HKa) on Adhesion and Survival Signaling in Endothelial Cells
- (2012) Lia Tesfay et al. PLoS One
- Fenton Reaction Induced Cancer in Wild Type Rats Recapitulates Genomic Alterations Observed in Human Cancer
- (2012) Shinya Akatsuka et al. PLoS One
- Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation
- (2012) J. Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigallocatechin Gallate (EGCG) Is the Most Effective Cancer Chemopreventive Polyphenol in Green Tea
- (2012) Guang-Jian Du et al. Nutrients
- The transferrin receptor and the targeted delivery of therapeutic agents against cancer
- (2011) Tracy R. Daniels et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy
- (2011) Y Yu et al. BRITISH JOURNAL OF PHARMACOLOGY
- A phase I and pharmacokinetic study of oral 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in the treatment of advanced-stage solid cancers: a California Cancer Consortium Study
- (2011) Joseph Chao et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Wnt Inhibitor Screen Reveals Iron Dependence of -Catenin Signaling in Cancers
- (2011) S. Song et al. CANCER RESEARCH
- Lipocalin 2: A multifaceted modulator of human cancer
- (2011) Jiang Yang et al. CELL CYCLE
- H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis
- (2011) Maddalena Di Sanzo et al. JOURNAL OF PROTEOME RESEARCH
- Novel Thiosemicarbazone Iron Chelators Induce Up-Regulation and Phosphorylation of the Metastasis Suppressor N-myc Down-Stream Regulated Gene 1: A New Strategy for the Treatment of Pancreatic Cancer
- (2011) Z. Kovacevic et al. MOLECULAR PHARMACOLOGY
- Silybin and the liver: From basic research to clinical practice
- (2011) Carmela Loguercio WORLD JOURNAL OF GASTROENTEROLOGY
- Nuclear ferritin: A new role for ferritin in cell biology
- (2010) Ahmed A. Alkhateeb et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Role of ferritin alterations in human breast cancer cells
- (2010) Svitlana I. Shpyleva et al. BREAST CANCER RESEARCH AND TREATMENT
- Phase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancer
- (2010) Allyson J. Ocean et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Effects of iron deficiency and iron overload on angiogenesis and oxidative stress—a potential dual role for iron in breast cancer
- (2010) Jinlong Jian et al. FREE RADICAL BIOLOGY AND MEDICINE
- Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells
- (2010) I. Andolfo et al. HAEMATOLOGICA
- The antitumor activity of the fungicide ciclopirox
- (2010) Hongyu Zhou et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of the proliferation and invasion of hepatocellular carcinoma cells by lipocalin 2 through blockade of JNK and PI3K/Akt signaling
- (2010) Kim INTERNATIONAL JOURNAL OF ONCOLOGY
- Regulation of Lung Cancer Cell Migration and Invasion by Reactive Oxygen Species and Caveolin-1
- (2010) Sudjit Luanpitpong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanisms of Motility in Metastasizing Cells
- (2010) Mahmut Yilmaz et al. MOLECULAR CANCER RESEARCH
- A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer
- (2010) Thomas W. Flaig et al. PROSTATE
- Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis
- (2010) Z. K. Pinnix et al. Science Translational Medicine
- Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells
- (2009) Y. Eberhard et al. BLOOD
- Specific iron chelators determine the route of ferritin degradation
- (2009) I. De Domenico et al. BLOOD
- TfR2 expression in human colon carcinomas
- (2009) Alessia Calzolari et al. BLOOD CELLS MOLECULES AND DISEASES
- Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro
- (2009) J. McLarty et al. Cancer Prevention Research
- 15-Deoxy-Δ 12,14 -prostaglandin J 2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS
- (2009) Do-Hee Kim et al. CARCINOGENESIS
- Lipocalin 2 Expressions Correlate Significantly With Tumor Differentiation in Epithelial Ovarian Cancer
- (2009) HanByoul Cho et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- NGAL decreases E-cadherin-mediated cell–cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells
- (2009) Limei Hu et al. LABORATORY INVESTIGATION
- Regulatory effects of ferritin on angiogenesis
- (2009) L. G. Coffman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipocalin 2 promotes breast cancer progression
- (2009) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications
- (2008) Elizabeth L. Mackenzie et al. ANTIOXIDANTS & REDOX SIGNALING
- Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator
- (2008) Y. Jiao et al. BLOOD
- Synthesis and anti-cancer activity of covalent conjugates of artemisinin and a transferrin-receptor targeting peptide
- (2008) Steve Oh et al. CANCER LETTERS
- Neutrophil Gelatinase-Associated Lipocalin: A Novel Suppressor of Invasion and Angiogenesis in Pancreatic Cancer
- (2008) Z. Tong et al. CANCER RESEARCH
- Overexpression of Cellular Iron Import Proteins Is Associated with Malignant Progression of Esophageal Adenocarcinoma
- (2008) J. Boult et al. CLINICAL CANCER RESEARCH
- Oxidative Stress and Iron Homeostasis: Mechanistic and Health Aspects
- (2008) Dimitrios Galaris et al. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
- Lactoferrin and Cancer Disease Prevention
- (2008) Lígia Rodrigues et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- Lactotransferrin: A candidate tumor suppressor-Deficient expression in human nasopharyngeal carcinoma and inhibition of NPC cell proliferation by modulating the mitogen-activated protein kinase pathway
- (2008) Yanhong Zhou et al. INTERNATIONAL JOURNAL OF CANCER
- Breast cancer expression of CD163, a macrophage scavenger receptor, is related to early distant recurrence and reduced patient survival
- (2008) Ivan Shabo et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of melanoma brain metastasis by targeting melanotransferrin at the cell surface
- (2008) Yannève Rolland et al. Pigment Cell & Melanoma Research
- The neutrophil gelatinase-associated lipocalin (NGAL), a NF- B-regulated gene, is a survival factor for thyroid neoplastic cells
- (2008) A. Iannetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Iron increases MMP-9 expression through activation of AP-1 via ERK/Akt pathway in human head and neck squamous carcinoma cells
- (2007) Ruchadaporn Kaomongkolgit et al. ORAL ONCOLOGY
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