期刊
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 49, 期 3, 页码 203-217出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10408390701856157
关键词
lactoferrin; chemoprevention; infection; inflammation; cancer
资金
- F. C. T. (Fundacao para a Ciencia e a Tecnologia) [SFRH/BPD/26064/2005]
Lactoferrin (LF) is an iron-binding glycoprotein that is composed of the transferrin family and is predominantly found in the products of the exocrine glands located in the gateways of the digestive, respiratory, and reproductive systems, suggesting a role in the non-specific defence against invading pathogens. Additionally, several physiological roles have been attributed to LF, namely regulation of iron homeostasis, host defence against infection and inflammation, regulation of cellular growth, and differentiation and protection against cancer development and metastasis. These findings have suggested LF's great potential therapeutic use in cancer disease prevention and/or treatment, namely as a chemopreventive agent. This review looks at the recent advances in understanding the mechanisms underlying the multifunctional roles of LF and future perspectives on its potential therapeutic applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据