A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies

First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

(2010) Suhail Ahmed Kabeer Rasheed et al.   INTERNATIONAL JOURNAL OF CANCER

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

(2010) Amy E. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production

(2010) Anne Hamacher-Brady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacogenomic Identification of c-Myc/Max-Regulated Genes Associated with Cytotoxicity of Artesunate towards Human Colon, Ovarian and Lung Cancer Cell Lines

(2010) Serkan Sertel et al.   MOLECULES

Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells

(2009) Mahmoud Youns et al.   BIOCHEMICAL PHARMACOLOGY

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

(2009) Martin Michaelis et al.   BIOCHEMICAL PHARMACOLOGY

Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo

(2009) Ji-Hui Du et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Role of Downstream Signaling Pathways of the Epidermal Growth Factor Receptor for Artesunates Activity in Cancer Cells

(2009) V. Konkimalla et al.   CURRENT CANCER DRUG TARGETS

Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NFκB p65

(2009) Shihui Li et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-κB

(2009) Hua Chen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Quantitative analysis of caspase-3 activation by fitting fluorescence emission spectra in living cells

(2009) Longxiang Wang et al.   MICRON

Artesunate Derived from Traditional Chinese Medicine Induces DNA Damage and Repair

(2008) P. C.H. Li et al.   CANCER RESEARCH

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

(2008) J. Hou et al.   CLINICAL CANCER RESEARCH

Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation

(2007) Ikuhiko Nakase et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS