Biomarkers for Alzheimer’s disease—preparing for a new era of disease-modifying therapies
出版年份 2020 全文链接
标题
Biomarkers for Alzheimer’s disease—preparing for a new era of disease-modifying therapies
作者
关键词
-
出版物
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-04-07
DOI
10.1038/s41380-020-0721-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia
- (2020) Shorena Janelidze et al. NATURE MEDICINE
- Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
- (2020) Elisabeth H. Thijssen et al. NATURE MEDICINE
- Inflammatory markers in Alzheimer’s disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies
- (2019) Xue-Ning Shen et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease
- (2019) Oliver Preische et al. NATURE MEDICINE
- Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease
- (2019) Philip S. J. Weston et al. Alzheimers Research & Therapy
- Targeting Apolipoprotein E for Alzheimer’s Disease: An Industry Perspective
- (2019) Georgette L. Suidan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neurofilament light chain as a biomarker in neurological disorders
- (2019) Lorenzo Gaetani et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease
- (2019) Oskar Hansson et al. Alzheimers Research & Therapy
- The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
- (2019) Carlo Sala Frigerio et al. Cell Reports
- Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease
- (2019) Niklas Mattsson et al. JAMA Neurology
- Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A)
- (2019) Songye Li et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- [18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer’s disease
- (2019) Sandra Sanabria Bohórquez et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Current and emerging avenues for Alzheimer's disease drug targets
- (2019) R. Loera‐Valencia et al. JOURNAL OF INTERNAL MEDICINE
- Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology
- (2019) Claire Bridel et al. JAMA Neurology
- Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease–Related β-Amyloid Status
- (2019) Sebastian Palmqvist et al. JAMA Neurology
- Staging β-Amyloid Pathology With Amyloid Positron Emission Tomography
- (2019) Niklas Mattsson et al. JAMA Neurology
- The neuropathological diagnosis of Alzheimer’s disease
- (2019) Michael A. DeTure et al. Molecular Neurodegeneration
- Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease
- (2019) Sebastian Palmqvist et al. EMBO Molecular Medicine
- Tau PET imaging with 18F-PI-2620 in patients with Alzheimer's disease and healthy controls: a first-in-human study
- (2019) Andre Mueller et al. JOURNAL OF NUCLEAR MEDICINE
- Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer’s disease
- (2019) Maria João Leitão et al. Alzheimers Research & Therapy
- Plasma biomarkers of astrocytic and neuronal dysfunction in early‐ and late‐onset Alzheimer's disease
- (2019) Fanny M. Elahi et al. Alzheimers & Dementia
- Cortical Microstructural Alterations in Mild Cognitive Impairment and Alzheimer’s Disease Dementia
- (2019) Nicholas M Vogt et al. CEREBRAL CORTEX
- Advances and considerations in AD tau-targeted immunotherapy
- (2019) Alice Bittar et al. NEUROBIOLOGY OF DISEASE
- Predicting clinical decline and conversion to Alzheimer’s disease or dementia using novel Elecsys Aβ(1–42), pTau and tTau CSF immunoassays
- (2019) Kaj Blennow et al. Scientific Reports
- Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology
- (2018) Erik Portelius et al. ACTA NEUROPATHOLOGICA
- Estimation of lifetime risks of Alzheimer's disease dementia using biomarkers for preclinical disease
- (2018) Ron Brookmeyer et al. Alzheimers & Dementia
- Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography
- (2018) Michelle M. Mielke et al. Alzheimers & Dementia
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
- (2018) John L Robinson et al. BRAIN
- In vivo characterization and quantification of neurofibrillary tau PET radioligand [18F]MK-6240 in humans from Alzheimer’s disease dementia to young controls
- (2018) Tobey J Betthauser et al. JOURNAL OF NUCLEAR MEDICINE
- High performance plasma amyloid-β biomarkers for Alzheimer’s disease
- (2018) Akinori Nakamura et al. NATURE
- Tau Kinetics in Neurons and the Human Central Nervous System
- (2018) Chihiro Sato et al. NEURON
- Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging
- (2018) Ming-Kai Chen et al. JAMA Neurology
- Are We Ready for Detecting α-Synuclein Prone to Aggregation in Patients? The Case of “Protein-Misfolding Cyclic Amplification” and “Real-Time Quaking-Induced Conversion” as Diagnostic Tools
- (2018) Silvia Paciotti et al. Frontiers in Neurology
- Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
- (2018) Bradley R. Groveman et al. Acta Neuropathologica Communications
- Evaluation of18F-RO-948 (18F-RO6958948) for quantitative assessment of tau accumulation in the human brain with positron emission tomography
- (2018) Hiroto Kuwabara et al. JOURNAL OF NUCLEAR MEDICINE
- Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers
- (2018) Cristian C. Constantinescu et al. MOLECULAR IMAGING AND BIOLOGY
- Neurofilaments as biomarkers in neurological disorders
- (2018) Michael Khalil et al. Nature Reviews Neurology
- Current state of Alzheimer’s fluid biomarkers
- (2018) José Luis Molinuevo et al. ACTA NEUROPATHOLOGICA
- The glymphatic pathway in neurological disorders
- (2018) Martin Kaag Rasmussen et al. LANCET NEUROLOGY
- Biomarkers for tau pathology
- (2018) Michael Schöll et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Fluid and PET biomarkers for amyloid pathology in Alzheimer's disease
- (2018) Ann D. Cohen et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- New insights into the role of TREM2 in Alzheimer’s disease
- (2018) Maud Gratuze et al. Molecular Neurodegeneration
- Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease
- (2018) Miia Kivipelto et al. Nature Reviews Neurology
- Increases of Plasma Levels of Glial Fibrillary Acidic Protein, Tau, and Amyloid β up to 90 Days after Traumatic Brain Injury
- (2017) Tanya Bogoslovsky et al. JOURNAL OF NEUROTRAUMA
- Tau PET imaging: present and future directions
- (2017) Laure Saint-Aubert et al. Molecular Neurodegeneration
- [18F]FDG PET signal is driven by astroglial glutamate transport
- (2017) Eduardo R Zimmer et al. NATURE NEUROSCIENCE
- Association between cerebrospinal fluid and plasma neurodegeneration biomarkers with brain atrophy in Alzheimer's disease
- (2017) Joana B. Pereira et al. NEUROBIOLOGY OF AGING
- Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers
- (2017) Kaitlin B. Casaletto et al. NEUROLOGY
- Review: Tau in biofluids - relation to pathology, imaging and clinical features
- (2017) H. Zetterberg NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain
- (2017) Kok Pin Ng et al. Alzheimers Research & Therapy
- Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid
- (2017) Mohammad Shahnawaz et al. JAMA Neurology
- TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia
- (2016) Bryan D. James et al. BRAIN
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
- (2016) Marc Suárez‐Calvet et al. EMBO Molecular Medicine
- Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: A View of the Regulatory Science Qualification Landscape from the Coalition Against Major Diseases CSF Biomarker Team
- (2016) Stephen P. Arnerić et al. JOURNAL OF ALZHEIMERS DISEASE
- Cerebrospinal Fluid Aβ42/40 Corresponds Better than Aβ42 to Amyloid PET in Alzheimer’s Disease
- (2016) Piotr Lewczuk et al. JOURNAL OF ALZHEIMERS DISEASE
- Altered Proteins in the Aging Brain
- (2016) Adila Elobeid et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
- (2016) Bob Olsson et al. LANCET NEUROLOGY
- Increased CSF neurogranin concentration is specific to Alzheimer disease
- (2016) Henrietta Wellington et al. NEUROLOGY
- Tauopathies as clinicopathological entities
- (2016) David J. Irwin PARKINSONISM & RELATED DISORDERS
- Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury
- (2016) M. Suarez-Calvet et al. Science Translational Medicine
- Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
- (2016) Graham Fairfoul et al. Annals of Clinical and Translational Neurology
- Plasma β-amyloid in Alzheimer’s disease and vascular disease
- (2016) Shorena Janelidze et al. Scientific Reports
- Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease
- (2015) Hlin Kvartsberg et al. Alzheimers & Dementia
- The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET
- (2015) William E. Klunk et al. Alzheimers & Dementia
- C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease
- (2015) Ann De Vos et al. Alzheimers & Dementia
- Cerebrospinal fluid tau and amyloid-β1-42in patients with dementia
- (2015) Tobias Skillbäck et al. BRAIN
- Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
- (2014) Bruno Dubois et al. LANCET NEUROLOGY
- Update on appropriate use criteria for amyloid PET imaging: Dementia experts, mild cognitive impairment, and education
- (2013) Keith A. Johnson et al. Alzheimers & Dementia
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- Biomarker Modeling of Alzheimer’s Disease
- (2013) Clifford R. Jack et al. NEURON
- Quantification of α-synuclein in cerebrospinal fluid: How ideal is this biomarker for Parkinson's disease?
- (2013) Brit Mollenhauer PARKINSONISM & RELATED DISORDERS
- Changes in Amyloid- and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein
- (2013) L. F. Maia et al. Science Translational Medicine
- Age and diagnostic performance of Alzheimer disease CSF biomarkers
- (2012) N. Mattsson et al. NEUROLOGY
- Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study
- (2012) Jeffrey Randall et al. RESUSCITATION
- An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28
- (2011) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The Translocator Protein
- (2011) A. M. Scarf et al. JOURNAL OF NUCLEAR MEDICINE
- Fluorodeoxyglucose positron emission tomography: emerging roles in the evaluation of putative Alzheimer's disease-modifying treatments
- (2011) Eric M. Reiman NEUROBIOLOGY OF AGING
- Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults
- (2011) B. C. Dickerson et al. NEUROLOGY
- The clinical use of structural MRI in Alzheimer disease
- (2010) Giovanni B. Frisoni et al. Nature Reviews Neurology
- Acceleration of hippocampal atrophy in a non-demented elderly population: the SNAC-K study
- (2009) Yi Zhang et al. INTERNATIONAL PSYCHOGERIATRICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search