Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A)

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

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Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers

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PET imaging of synaptic density: A new tool for investigation of neuropsychiatric diseases

(2018) Zhengxin Cai et al.   NEUROSCIENCE LETTERS

Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates

(2018) Songye Li et al.   ACS Chemical Neuroscience

Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

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Pharmacokinetic Characterization of [18F]UCB-H PET Radiopharmaceutical in the Rat Brain

(2017) Guillaume Becker et al.   MOLECULAR PHARMACEUTICS

Copper-catalysed aromatic-Finkelstein reactions with amine-based ligand systems

(2017) Xiaodong Jin et al.   Catalysis Science & Technology

Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer’s Mouse Phenotypes

(2017) Laura T. Haas et al.   Cell Reports

Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond

(2016) Wolfgang Löscher et al.   CNS DRUGS

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

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Erratum: Corrigendum: Concerted nucleophilic aromatic substitution with 19F− and 18F−

(2016) Constanze N. Neumann et al.   NATURE

[11C]UCB-A, a novel PET tracer for synaptic vesicle protein 2A

(2016) Sergio Estrada et al.   NUCLEAR MEDICINE AND BIOLOGY

Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF

(2016) Katarina J. Makaravage et al.   ORGANIC LETTERS

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Moving Metal-Mediated 18F-Fluorination from Concept to Clinic

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Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission

(2016) Kentaro Tokudome et al.   Scientific Reports

Fyn inhibition rescues established memory and synapse loss in Alzheimer mice

(2015) Adam C. Kaufman et al.   ANNALS OF NEUROLOGY

Biodistribution and Radiation Dosimetry for the Novel SV2A Radiotracer [18F]UCB-H: First-in-Human Study

(2015) F. Bretin et al.   MOLECULAR IMAGING AND BIOLOGY

Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18

(2015) Kerstin Sander et al.   Scientific Reports

A General Copper-Mediated Nucleophilic18F Fluorination of Arenes

(2014) Matthew Tredwell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands

(2014) Joël Mercier et al.   ChemMedChem

Evaluation of 18F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain

(2014) G. I. Warnock et al.   JOURNAL OF NUCLEAR MEDICINE

Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics

(2014) Benjamin H. Rotstein et al.   Nature Communications

Iodonium ylides for one-step, no-carrier-added radiofluorination of electron rich arenes, exemplified with 4-(([18F]fluorophenoxy)-phenylmethyl)piperidine NET and SERT ligands

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One-Pot Synthesis and Applications of N-Heteroaryl Iodonium Salts

(2014) Marcin Bielawski et al.   ChemistryOpen

Synaptic vesicle protein 2A: basic facts and role in synaptic function

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Optimization of PET–MR registrations for nonhuman primates using mutual information measures: A Multi-Transform Method (MTM)

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Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

(2012) P. E. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia

(2012) Manuel Mattheisen et al.   SCHIZOPHRENIA RESEARCH

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Synapse Pathology in Psychiatric and Neurologic Disease

(2010) Myrrhe van Spronsen et al.   Current Neurology and Neuroscience Reports

Functional changes in the frontal cortex in Parkinson’s disease using a rat model

(2010) Zhongyu Hou et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

(2009) Vincent J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Down-regulation Synaptic Vesicle Protein 2A in the Anterior Temporal Neocortex of Patients with Intractable Epilepsy

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