Are We Ready for Detecting α-Synuclein Prone to Aggregation in Patients? The Case of “Protein-Misfolding Cyclic Amplification” and “Real-Time Quaking-Induced Conversion” as Diagnostic Tools
出版年份 2018 全文链接
标题
Are We Ready for Detecting α-Synuclein Prone to Aggregation in Patients? The Case of “Protein-Misfolding Cyclic Amplification” and “Real-Time Quaking-Induced Conversion” as Diagnostic Tools
作者
关键词
-
出版物
Frontiers in Neurology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-06-06
DOI
10.3389/fneur.2018.00415
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA
- (2018) Katelyn Becker et al. MOLECULAR NEUROBIOLOGY
- Distinct α-Synuclein strains and implications for heterogeneity among α-Synucleinopathies
- (2018) Chao Peng et al. NEUROBIOLOGY OF DISEASE
- Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
- (2018) Bradley R. Groveman et al. Acta Neuropathologica Communications
- Discovery, validation and optimization of cerebrospinal fluid biomarkers for use in Parkinson’s disease
- (2017) Lucia Farotti et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC
- (2017) Kazunori Sano et al. MOLECULAR NEUROBIOLOGY
- Diagnosis and management of dementia with Lewy bodies
- (2017) Ian G. McKeith et al. NEUROLOGY
- Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification
- (2017) Ricardo Gaspar et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Prion Diagnosis: Application of Real-Time Quaking-Induced Conversion
- (2017) Hae-Eun Kang et al. Biomed Research International
- Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid
- (2017) Mohammad Shahnawaz et al. JAMA Neurology
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein
- (2017) David Ruzafa et al. PLoS One
- The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature
- (2016) Anja Hviid Simonsen et al. Biomarkers in Medicine
- Value of cerebrospinal fluid α-synuclein species as biomarker in Parkinson's diagnosis and prognosis
- (2016) Lucilla Parnetti et al. Biomarkers in Medicine
- Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele
- (2016) E.R. Padayachee et al. BRAIN RESEARCH
- Seeded Amplification of Chronic Wasting Disease Prions in Nasal Brushings and Recto-anal Mucosa-Associated Lymphoid Tissues from Elk by Real-Time Quaking-Induced Conversion
- (2016) Nicholas J. Haley et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Antemortem Detection of Chronic Wasting Disease Prions in Nasal Brush Collections and Rectal Biopsy Specimens from White-Tailed Deer by Real-Time Quaking-Induced Conversion
- (2016) Nicholas J. Haley et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Structural disorder of monomeric α-synuclein persists in mammalian cells
- (2016) Francois-Xavier Theillet et al. NATURE
- Molecular mechanisms of protein aggregation from global fitting of kinetic models
- (2016) Georg Meisl et al. Nature Protocols
- Diagnostic utility of CSF α-synuclein species in Parkinson's disease: protocol for a systematic review and meta-analysis
- (2016) Paolo Eusebi et al. BMJ Open
- Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
- (2016) Graham Fairfoul et al. Annals of Clinical and Translational Neurology
- Neuropathologically mixed Alzheimer’s and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes
- (2015) Lauren Walker et al. ACTA NEUROPATHOLOGICA
- A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes
- (2015) N K Magdalinou et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Role of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative Diseases
- (2015) Ronald Melki Journal of Parkinsons Disease
- Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein
- (2015) Maria E. Bernis et al. Acta Neuropathologica Communications
- Anti-amyloid Compounds Inhibit α-Synuclein Aggregation Induced by Protein Misfolding Cyclic Amplification (PMCA)
- (2014) Maria Eugenia Herva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evidence of Native α-Synuclein Conformers in the Human Brain
- (2014) Neal Gould et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of Chronic Wasting Disease in the Lymph Nodes of Free-Ranging Cervids by Real-Time Quaking-Induced Conversion
- (2014) Nicholas J. Haley et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversion
- (2014) D. M. Henderson et al. JOURNAL OF GENERAL VIROLOGY
- Correlates of cerebrospinal fluid levels of oligomeric- and total-α-synuclein in premotor, motor and dementia stages of Parkinson’s disease
- (2014) Yaroslau Compta et al. JOURNAL OF NEUROLOGY
- Presynaptic Alpha-Synuclein Aggregation in a Mouse Model of Parkinson's Disease
- (2014) K. J. Spinelli et al. JOURNAL OF NEUROSCIENCE
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- CSF biomarkers and clinical progression of Parkinson disease
- (2014) S. Hall et al. NEUROLOGY
- A Test for Creutzfeldt–Jakob Disease Using Nasal Brushings
- (2014) Christina D. Orrú et al. NEW ENGLAND JOURNAL OF MEDICINE
- Re-Assessment of PrPSc Distribution in Sporadic and Variant CJD
- (2014) Richard Rubenstein et al. PLoS One
- In vitro aggregation assays for the characterization of α-synuclein prion-like properties
- (2014) Joanna Narkiewicz et al. Prion
- Detection of Misfolded Aβ Oligomers for Sensitive Biochemical Diagnosis of Alzheimer’s Disease
- (2014) Natalia Salvadores et al. Cell Reports
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Analyses of Protease Resistance and Aggregation State of Abnormal Prion Protein across the Spectrum of Human Prions
- (2013) Daniela Saverioni et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay
- (2013) Paolo Arosio et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Temperature-Dependent Structural Changes of Parkinson's Alpha-Synuclein Reveal the Role of Pre-Existing Oligomers in Alpha-Synuclein Fibrillization
- (2013) Winny Ariesandi et al. PLoS One
- Rapid Antemortem Detection of CWD Prions in Deer Saliva
- (2013) Davin M. Henderson et al. PLoS One
- Prion-Seeding Activity in Cerebrospinal Fluid of Deer with Chronic Wasting Disease
- (2013) Nicholas J. Haley et al. PLoS One
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders
- (2012) Sara Hall et al. ARCHIVES OF NEUROLOGY
- Novel One-step Immunoassays to Quantify α-Synuclein
- (2012) Michael Bidinosti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylated -Synuclein in Parkinson's Disease
- (2012) Y. Wang et al. Science Translational Medicine
- Alpha-synuclein: from secretion to dysfunction and death
- (2012) O Marques et al. Cell Death & Disease
- A Kinetic Aggregation Assay Allowing Selective and Sensitive Amyloid-β Quantification in Cells and Tissues
- (2011) Deguo Du et al. BIOCHEMISTRY
- Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
- (2011) Samuel I. A. Cohen et al. JOURNAL OF CHEMICAL PHYSICS
- Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion
- (2011) A. H. Peden et al. JOURNAL OF GENERAL VIROLOGY
- Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion
- (2011) Ryuichiro Atarashi et al. NATURE MEDICINE
- Real-time quaking-induced conversion
- (2011) Ryuichiro Atarashi et al. Prion
- Strategies to increase the reproducibility of protein fibrillization in plate reader assays
- (2010) Lise Giehm et al. ANALYTICAL BIOCHEMISTRY
- Molecular mechanism of Thioflavin-T binding to amyloid fibrils
- (2010) Matthew Biancalana et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Quantification of α-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies
- (2010) Brit Mollenhauer et al. Biomarkers in Medicine
- Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins
- (2010) Jobin Varkey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits -Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions
- (2010) K. E. Paleologou et al. JOURNAL OF NEUROSCIENCE
- The human olfactory mucosa
- (2009) Pedro Alberto Escada et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Aggregation and Amyloid Fibril Formation Induced by Chemical Dimerization of Recombinant Prion Protein in Physiological-like Conditions
- (2009) Alireza Roostaee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of CWD Prions in Urine and Saliva of Deer by Transgenic Mouse Bioassay
- (2009) Nicholas J. Haley et al. PLoS One
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking
- (2008) Ryuichiro Atarashi et al. NATURE METHODS
- The fold of -synuclein fibrils
- (2008) M. Vilar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search