Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury
出版年份 2016 全文链接
标题
Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury
作者
关键词
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出版物
Science Translational Medicine
Volume 8, Issue 369, Pages 369ra178-369ra178
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-12-15
DOI
10.1126/scitranslmed.aag1767
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status
- (2016) Laura Piccio et al. ACTA NEUROPATHOLOGICA
- Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease
- (2016) Elena Rodriguez-Vieitez et al. BRAIN
- Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging
- (2016) Lorraine Hamelin et al. BRAIN
- TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance
- (2016) Xianyuan Xiang et al. EMBO Molecular Medicine
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
- (2016) Marc Suárez‐Calvet et al. EMBO Molecular Medicine
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
- (2016) Amanda Heslegrave et al. Molecular Neurodegeneration
- Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone
- (2016) Annika Öhrfelt et al. Multiple Sclerosis Journal
- TREM2 variants: new keys to decipher Alzheimer disease pathogenesis
- (2016) Marco Colonna et al. NATURE REVIEWS NEUROSCIENCE
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease
- (2016) Kristi Henjum et al. Alzheimers Research & Therapy
- Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone
- (2016) Annika Öhrfelt et al. Multiple Sclerosis Journal
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- TREM2 sustains microglial expansion during aging and response to demyelination
- (2015) Pietro Luigi Poliani et al. JOURNAL OF CLINICAL INVESTIGATION
- Imaging of neuroinflammation in dementia: a review
- (2015) James Stefaniak et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18 F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice
- (2015) Bin Liu et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- TREM2 and Risk of Alzheimer’s Disease — Friend or Foe?
- (2015) Rudolph E. Tanzi NEW ENGLAND JOURNAL OF MEDICINE
- Early astrocytosis in autosomal dominant Alzheimer’s disease measured in vivo by multi-tracer positron emission tomography
- (2015) Michael Schöll et al. Scientific Reports
- Factors Associated With the Onset and Persistence of Post–Lumbar Puncture Headache
- (2015) Andrés E. Monserrate et al. JAMA Neurology
- Human CNS immune senescence and neurodegeneration
- (2014) Wolfgang J Streit et al. CURRENT OPINION IN IMMUNOLOGY
- Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis
- (2014) D. C. Ryman et al. NEUROLOGY
- Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease
- (2014) A. M. Fagan et al. Science Translational Medicine
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias
- (2014) Gary W. Beecham et al. PLoS Genetics
- TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis
- (2014) Janet Cady et al. JAMA Neurology
- The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy
- (2013) Patrick L. McGeer et al. ACTA NEUROPATHOLOGICA
- In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease
- (2013) William C. Kreisl et al. BRAIN
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage
- (2013) Patrick Wunderlich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease
- (2013) Sruti Rayaprolu et al. Molecular Neurodegeneration
- Insights into TREM2 biology by network analysis of human brain gene expression data
- (2013) Paola Forabosco et al. NEUROBIOLOGY OF AGING
- A novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family
- (2013) Rita Guerreiro et al. NEUROBIOLOGY OF AGING
- Heterozygous TREM2 mutations in frontotemporal dementia
- (2013) Barbara Borroni et al. NEUROBIOLOGY OF AGING
- Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
- (2013) Elise Cuyvers et al. NEUROBIOLOGY OF AGING
- Missense variant in TREML2 protects against Alzheimer's disease
- (2013) Bruno A. Benitez et al. NEUROBIOLOGY OF AGING
- Biomarker Modeling of Alzheimer’s Disease
- (2013) Clifford R. Jack et al. NEURON
- Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).
- (2013) Martha Storandt et al. NEUROPSYCHOLOGY
- Neuroinflammation: The role and consequences
- (2013) Monty Lyman et al. NEUROSCIENCE RESEARCH
- Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement
- (2013) Rita João Guerreiro et al. JAMA Neurology
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease
- (2011) Alberto Serrano-Pozo et al. AMERICAN JOURNAL OF PATHOLOGY
- [18F]GE-180: A novel fluorine-18 labelled PET tracer for imaging Translocator protein 18kDa (TSPO)
- (2011) Harry Wadsworth et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease
- (2011) Randall J Bateman et al. Alzheimers Research & Therapy
- Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease
- (2010) Sudha Seshadri JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease
- (2009) Wolfgang J. Streit et al. ACTA NEUROPATHOLOGICA
- Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
- (2009) Clifford R Jack et al. LANCET NEUROLOGY
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation
- (2008) Laura Piccio et al. BRAIN
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