标题
Therapeutics and delivery vehicles for local treatment of osteomyelitis
作者
关键词
-
出版物
JOURNAL OF ORTHOPAEDIC RESEARCH
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-04-14
DOI
10.1002/jor.24689
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Adjuvant antibiotic‐loaded bone cement: Concerns with current use and research to make it work
- (2020) Edward M. Schwarz et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Adjunct phage treatment enhances the effectiveness of low antibiotic concentration against Staphylococcus aureus biofilms in vitro
- (2019) James Dickey et al. PLoS One
- Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associated Osteomyelitis
- (2019) Ryan Trombetta et al. Pharmaceutics
- Successful treatment of antibiotic resistant poly-microbial bone infection with bacteriophages and antibiotics combination
- (2019) Ran Nir-Paz et al. CLINICAL INFECTIOUS DISEASES
- Efficacy of novel nano-hydroxyapatite/polyurethane composite scaffolds with silver phosphate particles in chronic osteomyelitis
- (2019) Dongli Zhang et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- 2018 International Consensus Meeting on Musculoskeletal Infection: Research Priorities from the General Assembly Questions
- (2019) Edward M. Schwarz et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Lysostaphin and BMP-2 co-delivery reduces S. aureus infection and regenerates critical-sized segmental bone defects
- (2019) Christopher T. Johnson et al. Science Advances
- In vitro efficacy of gentamicin released from collagen sponge in eradication of bacterial biofilm preformed on hydroxyapatite surface
- (2019) Beata Maczynska et al. PLoS One
- Chitosan-polycaprolactone blend sponges for management of chronic osteomyelitis: A preliminary characterization and in vitro evaluation
- (2019) Vaishali Pawar et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Vancomycin-laden calcium phosphate-calcium sulfate composite allows bone formation in a rat infection model
- (2019) K. Keely Boyle et al. PLoS One
- CRISPR-Cas9 modified bacteriophage for treatment of Staphylococcus aureus induced osteomyelitis and soft tissue infection
- (2019) Leah H. Cobb et al. PLoS One
- Biological and antibacterial properties of the micro-nanostructured hydroxyapatite/chitosan coating on titanium
- (2019) Baoe Li et al. Scientific Reports
- Local Delivery of Amikacin and Vancomycin from Chitosan Sponges Prevent Polymicrobial Implant-Associated Biofilm
- (2018) Logan R Boles et al. MILITARY MEDICINE
- Ciprofloxacin and Rifampin Dual Antibiotic-Loaded Biopolymer Chitosan Sponge for Bacterial Inhibition
- (2018) Carlos M Wells et al. MILITARY MEDICINE
- Hydrogel delivery of lysostaphin eliminates orthopedic implant infection byStaphylococcus aureusand supports fracture healing
- (2018) Christopher T. Johnson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy
- (2018) Frank Oechslin Viruses-Basel
- Designing Antibacterial Peptides with Enhanced Killing Kinetics
- (2018) Faiza H. Waghu et al. Frontiers in Microbiology
- Treatment of osteomyelitis defects by a vancomycin-loaded gelatin/β-tricalcium phosphate composite scaffold
- (2018) J. Zhou et al. Bone & Joint Research
- Magnetic Glycol Chitin-Based Hydrogel Nanocomposite for Combined Thermal and d-Amino-Acid-Assisted Biofilm Disruption
- (2018) Eric C. Abenojar et al. ACS Infectious Diseases
- Targeting Virulence in Staphylococcus aureus by Chemical Inhibition of the Accessory Gene Regulator System In Vivo
- (2018) Akram M. Salam et al. mSphere
- Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections
- (2018) Rachit Agarwal et al. Nature Biomedical Engineering
- Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters
- (2018) Clément Vulin et al. Nature Communications
- Bacteriophage Therapy: Clinical Trials and Regulatory Hurdles
- (2018) Lucy L. Furfaro et al. Frontiers in Cellular and Infection Microbiology
- Synergistic effect of vancomycin and l-homocarnosine alleviates Staphylococcus aureus-induced osteomyelitis in rats
- (2018) Panyu Zhou et al. BIOMEDICINE & PHARMACOTHERAPY
- In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments
- (2018) G. Mestres et al. Materials Science & Engineering C-Materials for Biological Applications
- Testing the efficacy of antimicrobial peptides in the topical treatment of induced osteomyelitis in rats
- (2017) Pavel Melicherčík et al. FOLIA MICROBIOLOGICA
- Silver nanoparticle deposited implants to treat osteomyelitis
- (2017) Samit Kumar Nandi et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
- Testing of a bioactive, moldable bone graft substitute in an infected, critically sized segmental defect model
- (2017) Matt E. Brown et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
- Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis
- (2017) Karen L de Mesy Bentley et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Thermally triggered release of the bacteriophage endolysin CHAPK and the bacteriocin lysostaphin for the control of methicillin resistant Staphylococcus aureus (MRSA)
- (2017) Hollie Hathaway et al. JOURNAL OF CONTROLLED RELEASE
- Controlled and Localized Nitric Oxide Precursor Delivery From Chitosan Gels to Staphylococcus aureus Biofilms
- (2017) Sayeed Hasan et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Antibiotic loaded microspheres as antimicrobial delivery systems for medical applications
- (2017) J. Szczeblinska et al. Materials Science & Engineering C-Materials for Biological Applications
- Carboxylated chitosan/silver-hydroxyapatite hybrid microspheres with improved antibacterial activity and cytocompatibility
- (2017) Juan Shen et al. Materials Science & Engineering C-Materials for Biological Applications
- Natural polymeric microspheres for modulated drug delivery
- (2017) Costantino Del Gaudio et al. Materials Science & Engineering C-Materials for Biological Applications
- Antibacterial silk fibroin/nanohydroxyapatite hydrogels with silver and gold nanoparticles for bone regeneration
- (2017) Marta Ribeiro et al. Nanomedicine-Nanotechnology Biology and Medicine
- The mechanism of human β-defensin 3 in MRSA-induced infection of implant drug-resistant bacteria biofilm in the mouse tibial bone marrow
- (2017) Chen Zhu et al. Experimental and Therapeutic Medicine
- Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: preparation, characterization and application in a vaginal drug delivery system
- (2017) Liqian Ci et al. Acta Pharmaceutica Sinica B
- Repurposing the Nonsteroidal Anti-inflammatory Drug Diflunisal as an Osteoprotective, Antivirulence Therapy for Staphylococcus aureus Osteomyelitis
- (2016) Andrew S. Hendrix et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Biodegradable Mg-Cu alloy implants with antibacterial activity for the treatment of osteomyelitis: In vitro and in vivo evaluations
- (2016) Yang Li et al. BIOMATERIALS
- A new model of implant-related osteomyelitis in the metaphysis of rat tibiae
- (2016) Norbert Harrasser et al. BMC MUSCULOSKELETAL DISORDERS
- Synergistic antimicrobial activity of bacteriophages and antibiotics against Staphylococcus aureus
- (2016) Ara Jo et al. FOOD SCIENCE AND BIOTECHNOLOGY
- Phage therapy of staphylococcal chronic osteomyelitis in experimental animal model
- (2016) Gopal Nath et al. INDIAN JOURNAL OF MEDICAL RESEARCH
- Development of nanoantibiotic delivery system using cockle shell-derived aragonite nanoparticles for treatment of osteomyelitis
- (2016) Lamin Saidykhan et al. International Journal of Nanomedicine
- A therapeutic delivery system for chronic osteomyelitis via a multi-drug implant based on three-dimensional printing technology
- (2016) Weigang Wu et al. JOURNAL OF BIOMATERIALS APPLICATIONS
- A novel, multi-barrier, drug eluting calcium sulfate/biphasic calcium phosphate biodegradable composite bone cement for treatment of experimental MRSA osteomyelitis in rabbit model
- (2016) Surajit Mistry et al. JOURNAL OF CONTROLLED RELEASE
- Polymicrobial Biofilm Inhibition Effects of Acetate-Buffered Chitosan Sponge Delivery Device
- (2016) Jessica Amber Jennings et al. MACROMOLECULAR BIOSCIENCE
- An experimental design approach to the preparation of pegylated polylactide-co-glicolide gentamicin loaded microparticles for local antibiotic delivery
- (2016) Rossella Dorati et al. Materials Science & Engineering C-Materials for Biological Applications
- Surgical Debridement Is Superior to Sole Antibiotic Therapy in a Novel Murine Posttraumatic Osteomyelitis Model
- (2016) Johannes Maximilian Wagner et al. PLoS One
- An Injectable In-Situ Conducting Thermosensitive Gel for Controlled Delivery of Vancomycin in Osteomyelitis Treatment and Bone Regeneration
- (2016) R. S. L. Aparna et al. Science of Advanced Materials
- An effective treatment of experimental osteomyelitis using the antimicrobial titanium/silver-containing nHP66 (nano-hydroxyapatite/polyamide-66) nanoscaffold biomaterials
- (2016) Minpeng Lu et al. Scientific Reports
- A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA)
- (2016) Fatma Elzahraa Akram et al. Annals of Clinical Microbiology and Antimicrobials
- The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release
- (2016) Gilles Brackman et al. Scientific Reports
- Poly(N-isopropylacrylamide-co-allylamine) (PNIPAM-co-ALA) nanospheres for the thermally triggered release of Bacteriophage K
- (2015) Hollie Hathaway et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Staphylococcus aureus Adapts to Oxidative Stress by Producing H2O2-Resistant Small-Colony Variants via the SOS Response
- (2015) Kimberley L. Painter et al. INFECTION AND IMMUNITY
- Staphylococcus aureusdevelops increased resistance to antibiotics by forming dynamic small colony variants during chronic osteomyelitis
- (2015) L. Tuchscherr et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Local Delivery of the Cationic Steroid Antibiotic CSA-90 Enables Osseous Union in a Rat Open Fracture Model of Staphylococcus aureus Infection
- (2015) Aaron Schindeler et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Injectable gellan gum-based nanoparticles-loaded system for the local delivery of vancomycin in osteomyelitis treatment
- (2015) Urszula Posadowska et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Preparation and characterization of dry powder bacteriophage K for intestinal delivery through oral administration
- (2015) Zhenxing Tang et al. LWT-FOOD SCIENCE AND TECHNOLOGY
- APD3: the antimicrobial peptide database as a tool for research and education
- (2015) Guangshun Wang et al. NUCLEIC ACIDS RESEARCH
- Cell shape dynamics during the staphylococcal cell cycle
- (2015) João M. Monteiro et al. Nature Communications
- Oxidized alginate hydrogels for bone morphogenetic protein-2 delivery in long bone defects
- (2014) Lauren B. Priddy et al. Acta Biomaterialia
- d-Amino Acids Enhance the Activity of Antimicrobials against Biofilms of Clinical Wound Isolates of Staphylococcus aureus and Pseudomonas aeruginosa
- (2014) Carlos J. Sanchez et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Triggered Release of Bacteriophage K from Agarose/Hyaluronan Hydrogel Matrixes by Staphylococcus aureus Virulence Factors
- (2014) Jessica E. Bean et al. CHEMISTRY OF MATERIALS
- Local Gentamicin Delivery From Resorbable Viscous Hydrogels Is Therapeutically Effective
- (2014) Derek Overstreet et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis
- (2014) Karen E Beenken et al. JOURNAL OF BIOMATERIALS APPLICATIONS
- Characterization of local delivery with amphotericin B and vancomycin from modified chitosan sponges and functional biofilm prevention evaluation
- (2014) Ashley Cox Parker et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- The Potential Role of Increasing the Release of Mouse β- Defensin-14 in the Treatment of Osteomyelitis in Mice: A Primary Study
- (2014) Chen Zhu et al. PLoS One
- A Novel Injectable Borate Bioactive Glass Cement as an Antibiotic Delivery Vehicle for Treating Osteomyelitis
- (2014) Hao Ding et al. PLoS One
- Bacteriophage Mediated Killing of Staphylococcus aureus In Vitro on Orthopaedic K Wires in Presence of Linezolid Prevents Implant Colonization
- (2014) Sandeep Kaur et al. PLoS One
- Lysostaphin-Coated Titan-Implants Preventing Localized Osteitis by Staphylococcus aureus in a Mouse Model
- (2014) Ceylan D. Windolf et al. PLoS One
- Phage Neutralization by Sera of Patients Receiving Phage Therapy
- (2014) Marzanna Łusiak-Szelachowska et al. VIRAL IMMUNOLOGY
- Selective Chemical Inhibition of agr Quorum Sensing in Staphylococcus aureus Promotes Host Defense with Minimal Impact on Resistance
- (2014) Erin K. Sully et al. PLoS Pathogens
- Staphylococcus aureus small colony variants show common metabolic features in central metabolism irrespective of the underlying auxotrophism
- (2014) André Kriegeskorte et al. Frontiers in Cellular and Infection Microbiology
- The Changing Epidemiology of Methicillin-Resistant Staphylococcus aureus in the United States: A National Observational Study
- (2013) Eili Y. Klein et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Effects of local delivery of d-amino acids from biofilm-dispersive scaffolds on infection in contaminated rat segmental defects
- (2013) Carlos J. Sanchez et al. BIOMATERIALS
- Structural and functional stabilization of phage particles in carbohydrate matrices for bacterial biosensing
- (2013) Victor M. Balcão et al. ENZYME AND MICROBIAL TECHNOLOGY
- Chimeric Ply187 endolysin killsStaphylococcus aureusmore effectively than the parental enzyme
- (2013) Jinzhe Mao et al. FEMS MICROBIOLOGY LETTERS
- Biofilm Matrix Exoproteins Induce a Protective Immune Response against Staphylococcus aureus Biofilm Infection
- (2013) Carmen Gil et al. INFECTION AND IMMUNITY
- Efficacy of antibacterial-loaded coating in an in vivo model of acutely highly contaminated implant
- (2013) Gianluca Giavaresi et al. INTERNATIONAL ORTHOPAEDICS
- Bacteriophage Therapy in Implant-Related Infections
- (2013) Cengiz Yilmaz et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Long Bone Osteomyelitis in Adults: Fundamental Concepts and Current Techniques
- (2013) Julia Sanders et al. ORTHOPEDICS
- National Burden of Invasive Methicillin-ResistantStaphylococcus aureusInfections, United States, 2011
- (2013) Raymund Dantes JAMA Internal Medicine
- Economic Burden of Periprosthetic Joint Infection in the United States
- (2012) Steven M. Kurtz et al. JOURNAL OF ARTHROPLASTY
- Highly stable, protein capped gold nanoparticles as effective drug delivery vehicles for amino-glycosidic antibiotics
- (2012) Lori Rastogi et al. Materials Science & Engineering C-Materials for Biological Applications
- Novel Chimerical Endolysins with Broad Antimicrobial Activity Against Methicillin-Resistant Staphylococcus aureus
- (2012) Sofia Fernandes et al. Microbial Drug Resistance
- Bacteriophages and their Implications on Future Biotechnology: A Review
- (2012) Irshad UL Haq et al. Virology Journal
- Quorum Sensing Inhibitors Increase the Susceptibility of Bacterial Biofilms to Antibiotics In Vitro and In Vivo
- (2011) Gilles Brackman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Characterization of inducedStaphylococcus aureusbacteriophage SAP-26 and its anti-biofilm activity with rifampicin
- (2011) Marzia Rahman et al. BIOFOULING
- Hydrophobic polycationic coatings that inhibit biofilms and support bone healing during infection
- (2011) Thomas P. Schaer et al. BIOMATERIALS
- Keratin hydrogels support the sustained release of bioactive ciprofloxacin
- (2011) Justin M. Saul et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Antibacterial effect of 317L stainless steel contained copper in prevention of implant-related infection in vitro and in vivo
- (2011) Hongwei Chai et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Antibacterial and anti-adhesive zeolite coatings on titanium alloy surface
- (2011) Jincheng Wang et al. MICROPOROUS AND MESOPOROUS MATERIALS
- Designing antimicrobial peptides: form follows function
- (2011) Christopher D. Fjell et al. NATURE REVIEWS DRUG DISCOVERY
- Highly Selective End-Tagged Antimicrobial Peptides Derived from PRELP
- (2011) Martin Malmsten et al. PLoS One
- A play in four acts: Staphylococcus aureus abscess formation
- (2011) Alice G. Cheng et al. TRENDS IN MICROBIOLOGY
- Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs
- (2010) Lenka Monincová et al. AMINO ACIDS
- Treatment with Linezolid or Vancomycin in Combination with Rifampin Is Effective in an Animal Model of Methicillin-ResistantStaphylococcus aureusForeign Body Osteomyelitis
- (2010) Paschalis Vergidis et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Teicoplanin-loaded borate bioactive glass implants for treating chronic bone infection in a rabbit tibia osteomyelitis model
- (2010) Xin Zhang et al. BIOMATERIALS
- Treatment of osteomyelitis with teicoplanin-encapsulated biodegradable thermosensitive hydrogel nanoparticles
- (2010) Kuo-Ti Peng et al. BIOMATERIALS
- The effectiveness of the controlled release of gentamicin from polyelectrolyte multilayers in the treatment of Staphylococcus aureus infection in a rabbit bone model
- (2010) Joshua S. Moskowitz et al. BIOMATERIALS
- Enhanced alginate microspheres as means of oral delivery of bacteriophage for reducing Staphylococcus aureus intestinal carriage
- (2010) Yongsheng Ma et al. FOOD HYDROCOLLOIDS
- Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model
- (2010) Bing Li et al. JOURNAL OF CONTROLLED RELEASE
- To protect peptide pharmaceuticals against peptidases
- (2010) R. Rink et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Lasioglossins: Three Novel Antimicrobial Peptides from the Venom of the Eusocial BeeLasioglossum laticeps(Hymenoptera: Halictidae)
- (2009) Václav Čeřovský et al. CHEMBIOCHEM
- The Effects of Farnesol on Staphylococcus aureus Biofilms and Osteoblasts
- (2009) Aasis Unnanuntana et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense
- (2009) Yuping Lai et al. TRENDS IN IMMUNOLOGY
- Topical versus Systemic Antimicrobial Therapy for Treating Mildly Infected Diabetic Foot Ulcers: A Randomized, Controlled, Double‐Blinded, Multicenter Trial of Pexiganan Cream
- (2008) Benjamin A. Lipsky et al. CLINICAL INFECTIOUS DISEASES
- The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA
- (2008) Stephen C. Becker et al. FEMS MICROBIOLOGY LETTERS
- The evolution of Staphylococcus aureus
- (2008) Ruud H. Deurenberg et al. INFECTION GENETICS AND EVOLUTION
- Phage therapy experience at the Eliava Institute
- (2008) M. Kutateladze et al. MEDECINE ET MALADIES INFECTIEUSES
- Bottom-Up Assembly of Hydrogels from Bacteriophage and Au Nanoparticles: The Effect of Cis- and Trans-Acting Factors
- (2008) Glauco R. Souza et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started