Article
Chemistry, Physical
Raghu Solanki, Krunal Patel, Sunita Patel
Summary: In this study, BBR-BSA NPs were synthesized by encapsulating berberine in bovine serum albumin nanoparticles using the desolvation method. The nanoparticles showed anticancer activity against breast cancer cells, indicating their potential therapeutic use as a novel paradigm for breast cancer treatment.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Engineering, Environmental
Lu Ding, Yanyu Zhao, Huihui Li, Qiujuan Zhang, Weiting Yang, Bo Fu, Qinhe Pan
Summary: Fluorescent probes with in-situ visual feature have gained attention for detecting doxycycline (DC), a widely used tetracycline antibiotic in animal husbandry. Bovine serum albumin-capped gold nanoclusters (BSA-AuNCs) were used as a ratiometric fluorescent probe to selectively detect DC among tetracycline antibiotics. BSA-AuNCs showed the highest response toward DC, with simple synthesis, short response time (1 min), and low detection limit. This work proposes an efficient strategy for designing fluorescent probes to selectively detect DC among tetracycline antibiotics.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Food Science & Technology
Lan Wang, Jin Mao, Qi Zhou, Qianchun Deng, Lei Zheng, Jie Shi
Summary: Curcumin-loaded bovine serum albumin/carboxymethylpachymaran nanoparticles (BMCNPs) were fabricated to enhance the solubility and stability of curcumin. The optimized BMCNPs had excellent encapsulation efficiency and showed sustained release of curcumin in the small intestine stage. In vitro cytotoxicity tests also confirmed the biocompatibility of BMCNPs.
Article
Pharmacology & Pharmacy
Salma El-Sayed Radwan, Riham M. El-Moslemany, Radwa A. Mehanna, Eman H. Thabet, Elsayeda-Zeinab A. Abdelfattah, Amal El-Kamel
Summary: This study developed chitosan-coated bovine serum albumin nanoparticles (CS-BSA-NPs) for the delivery of tetrandrine (TET) in the management of glaucoma. The CS-BSA-NPs showed enhanced corneal permeation and biocompatibility, as well as improved cellular uptake, antioxidant, and anti-proliferative properties compared to uncoated nanoparticles.
Review
Biochemistry & Molecular Biology
Raghu Solanki, Hadis Rostamabadi, Sunita Patel, Seid Mahdi Jafari
Summary: Bovine serum albumin nanoparticles (BSA NPs) are promising for efficient anti-cancer drug delivery due to their non-toxicity, non-immunogenicity, biodegradability, biocompatibility, and high drug-binding capacity. Understanding the structural/physicochemical features of BSA molecule and its derived nanovehicles, as well as effective variables in delivery mechanism, is essential for leveraging the potential of this carrier in cancer therapy. The review highlights recent advances in using BSA NPs for delivering anti-cancer agents and discusses the factors influencing the efficiency of therapeutics in nano-delivery systems.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Pharmacology & Pharmacy
Dina Saeed Ghataty, Reham Ibrahim Amer, Mai A. Amer, Mohamed F. Abdel F. Rahman, Rehab Nabil Shamma
Summary: A simple and green method was used to produce highly fluorescent carbon dots using bovine serum albumin. These carbon dots, with excellent fluorescence and stability, were investigated as nano-biocarriers for drug delivery, showing great potential in promoting wound healing.
Article
Multidisciplinary Sciences
Ali Mohammadi, Hossein Danafar
Summary: Cancer is a common cause of death worldwide and curcumin is a natural anticancer therapeutic with limited or no negative effects. However, its therapeutic applications are limited due to its hydrophobic nature and poor bioavailability. In this study, Bovine Serum Albumin-Coated Copper Sulfide nanoparticles were synthesized for curcumin drug delivery. The nanoparticles were characterized and their release pattern, hemotoxicity, and cytotoxicity were investigated. The results showed that the synthesized nanoparticles had a high CUR loading and its release was dependent on pH. The nanoparticles exhibited no toxicity and could be considered as a suitable candidate for drug delivery.
Article
Nanoscience & Nanotechnology
Tianzi Geng, Lining Zhao, Di Wu, Hongxin Zhang, Xiaolong Zhao, Meng Jiao, Leyong Zeng
Summary: In this study, ultrasmall AuNC bombined with BSA nanospheres to form stable and biocompatible AuNCs@BSA nanoprobes, which showed enhanced fluorescence emission and singlet oxygen yield compared to single AuNCs. The nanoprobes exhibited lower cytotoxicity, stronger cellular uptake, and significantly improved cell viability and tumor elimination in PDT applications. The results demonstrated that AuNCs@BSA;nanoprobes have great potential for efficient PDT due to their safety and reliability.
ACS APPLIED NANO MATERIALS
(2021)
Article
Pharmacology & Pharmacy
Farhan Alshammari, Bushra Alshammari, Afrasim Moin, Abdulwahab Alamri, Turki Al Hagbani, Ahmed Alobaida, Abu Baker, Salman Khan, Syed Mohd Danish Rizvi
Summary: Ceftriaxone-loaded gold nanoparticles showed better efficacy and targeting against bacterial strains compared to pure ceftriaxone.
Review
Polymer Science
Viktoria Hornok
Summary: This paper summarizes the research results on serum albumin-based nanoparticles for drug delivery purposes, focusing on their preparation techniques, synthesis parameters, and successful clinical applications. Despite promising possibilities, products made from different types of albumin nanoparticles, with the exception of a few, have not been invented yet. The paper also discusses promising applications of serum albumin nanoparticles for various biomedical purposes, such as carriers, delivery systems, and contrast agents.
Article
Chemistry, Multidisciplinary
Chihiro Mochizuki, Junna Nakamura, Michihiro Nakamura
Summary: Researchers successfully prepared adhesive cell-like FBS-copper phosphate hybrid particles, which showed toxicity towards cancer cells under cell culture conditions and have great potential for various applications.
Article
Chemistry, Applied
Run-Hui Ma, Wei Wang, Cai-Ping Hou, Yi-Fei Man, Zhi-Jing Ni, Kiran Thakur, Jian-Guo Zhang, Zhao-Jun Wei
Summary: It was found that bovine serum albumin (BSA) and glycosylated bovine serum albumin (GBSA) prepared in a nature deep eutectic solvent system show stronger interactions with kaempferol (Kae). GBSA-Kae nanoparticles (NPs) exhibited higher zeta-potential values, lower polydispersity index (PDI), higher encapsulation efficiency (EE), and loading capacity (LC) compared to BSA-Kae NPs. Structural characterization and stability analysis confirmed the stability of GBSA-Kae NPs. This study provides a theoretical foundation for improving the solubility and stability of Kae during its delivery and transport.
Article
Biophysics
Joana B. Ferrado, Adrian A. Perez, Malen Menegon, Victoria A. Vaillard, Fatima Gasser, Maria E. Baravalle, Hugo H. Ortega, Santiago E. Vaillard, Liliana G. Santiago
Summary: In this study, self-assembled bovine serum albumin nanoparticles loaded with genistein were PEGylated to avoid possible immunogenic reactions and rapid clearance from the bloodstream. The PEGylation process increased the particle size of the nanoparticles and improved their biological properties, reducing cytotoxicity and genotoxicity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Applied
Zhihuan Zang, Shurui Chou, Xu Si, Huijun Cui, Hui Tan, Yumeng Ding, Ziyue Liu, Haotian Wang, Yuxi Lang, Siyi Tang, Bin Li, Jinlong Tian
Summary: The addition of bovine serum albumin was found to improve the stability and antioxidant capacity of blueberry anthocyanins, providing a new approach for their application.
Article
Food Science & Technology
Zhihuan Zang, Shurui Chou, Lijuan Geng, Xu Si, Yumeng Ding, Yuxi Lang, Huijun Cui, Ningxuan Gao, Yi Chen, Mingshuang Wang, Xu Xie, Bo Xue, Bin Li, Jinlong Tian
Summary: The interactions between proteins and anthocyanins can enhance the stability and functional properties of anthocyanins, leading to improved quality of blueberry products.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Aruna Jyothi Kora, Lori Rastogi
ARABIAN JOURNAL OF CHEMISTRY
(2018)
Article
Biochemical Research Methods
Aruna Jyothi Kora
IET NANOBIOTECHNOLOGY
(2018)
Article
Chemistry, Analytical
Aruna Jyothi Kora, Lori Rastogi
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Analytical
Lori Rastogi, A. Durga Prasad, R. Manjusha, K. Dash, Sunil Jai Kumar
ACCREDITATION AND QUALITY ASSURANCE
(2019)
Article
Biochemical Research Methods
Aruna Jyothi Kora
IET NANOBIOTECHNOLOGY
(2019)
Article
Polymer Science
Aruna Jyothi Kora
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2019)
Article
Chemistry, Multidisciplinary
Aruna Jyothi Kora, K. Madhavi, N. N. Meeravali, Sunil Jai Kumar
ARABIAN JOURNAL OF CHEMISTRY
(2020)
Article
Mycology
Aruna Jyothi Kora, J. Mounika, R. Jagadeeshwar
Article
Chemistry, Analytical
Venkata Balarama Krishna Mullapudi, Arthi Salveru, Aruna Jyothi Kora
Summary: A simple in-house UV-photolysis setup was used to degrade cationic and anionic dyes. The optimization process determined the appropriate parameters for complete degradation of the dyes. The study also showed that the presence of common ions in dye effluents had minimal effect on the degradation efficiency. The developed method was successfully applied to real textile wastewater treatment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Thangavel Shanmugam, Venkata Balarama Krishna Mullapudi, Sunitha Yerroju, Aruna Jyothi Kora, Sanjiv Kumar
Summary: Covellite synthesized using sodium sulfide as the precipitant efficiently adsorbs both As(III) and As(V) from water without requiring any pretreatment steps. The adsorption process is fast and follows the Freundlich isotherm. The presence of both forms of arsenic in the adsorbed state is confirmed chemically, and the desorption of Cu-3(AsO4)(2) is affected in <2.0 pH HCl.
SEPARATION SCIENCE AND TECHNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Aruna Jyothi Kora
Summary: Vinayaka Chaviti is a traditional festival in India that is celebrated to fight seasonal diseases and infections. During this festival, Lord Ganesha is worshipped for wisdom, wealth, and health. The festival involves the use of medicinal leaves for worship, which also helps in preventing the spread of diseases and mosquito breeding. It emphasizes the importance of nature and recycling. However, the use of harmful materials in making Ganesh idols is a concern for the environment and human health.
ADVANCES IN TRADITIONAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Aruna Jyothi Kora
Summary: In this study, silver nanoparticles were successfully synthesized using a pressure cooker and autoclaving, confirming the dual functional role of tree gum as a reductant and stabilizer. This method provides a practical approach for production in resource-limited small laboratories.
Article
Chemistry, Applied
Aruna Jyothi Kora
Summary: Copper oxide nanoparticles capped with gum ghatti were successfully synthesized and shown to have antifungal activity against plant pathogens. The nanoparticles exhibited characteristic absorption and a monoclinic crystal structure. The gum capping was confirmed by FTIR spectra. The nanoparticles inhibited the growth of Rhizoctonia solani mycelia and sclerotia, making them a potential fungicidal formulation for controlling fungal diseases in a broad range of crops.
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Aruna Jyothi Kora
BIORESOURCES AND BIOPROCESSING
(2018)
Article
Oceanography
Aruna Jyothi Kora
INDIAN JOURNAL OF GEO-MARINE SCIENCES
(2018)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
