G-Protein-Coupled Receptors in CNS: A Potential Therapeutic Target for Intervention in Neurodegenerative Disorders and Associated Cognitive Deficits

Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death

(2019) Md. Jakaria et al.   MOLECULAR NEUROBIOLOGY

Inflammatory process in Parkinson disease: neuroprotection by Neuropeptide Y

(2019) Stéphanie Pain et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention

(2019) Courtney A. Marshall et al.   NEUROPHARMACOLOGY

Cellular, Synaptic and Network Effects of Acetylcholine in the Neocortex

(2019) Cristina Colangelo et al.   Frontiers in Neural Circuits

Gi/o-Protein Coupled Receptors in the Aging Brain

(2019) Patrícia G. de Oliveira et al.   Frontiers in Aging Neuroscience

Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on TLR4 Signaling

(2019) Shofiul Azam et al.   Frontiers in Immunology

Taurine and its analogs in neurological disorders: Focus on therapeutic potential and molecular mechanisms

(2019) Md. Jakaria et al.   Redox Biology

Roles of Neuropeptide Y in Neurodegenerative and Neuroimmune Diseases

(2019) Chunrong Li et al.   Frontiers in Neuroscience

Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease

(2019) Md. Ezazul Haque et al.   MOVEMENT DISORDERS

The adenosine A2A receptor antagonist SCH58261 reduces macrophage/microglia activation and protects against experimental autoimmune encephalomyelitis in mice

(2019) Yu Chen et al.   NEUROCHEMISTRY INTERNATIONAL

Potential Therapeutic Targets of Quercetin and Its Derivatives: Its Role in the Therapy of Cognitive Impairment

(2019) Jakaria et al.   Journal of Clinical Medicine

The Methanol Extract of Allium cepa L. Protects Inflammatory Markers in LPS-Induced BV-2 Microglial Cells and Upregulates the Antiapoptotic Gene and Antioxidant Enzymes in N27-A Cells

(2019) Md. Jakaria et al.   Antioxidants

Lipid-based nanodelivery approaches for dopamine-replacement therapies in Parkinson's disease: From preclinical to translational studies

(2019) Govindarajan Karthivashan et al.   BIOMATERIALS

The G protein-coupled receptors deorphanization landscape

(2018) Céline Laschet et al.   BIOCHEMICAL PHARMACOLOGY

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy

(2018) Sang-Won Min et al.   JOURNAL OF NEUROSCIENCE

G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

(2018) Krishna Sriram et al.   MOLECULAR PHARMACOLOGY

Sirtuin 1 and Alzheimer's disease: An up-to-date review

(2018) Liara Rizzi et al.   NEUROPEPTIDES

Examination of the effects of cannabinoid ligands on decision making in a rat gambling task

(2018) Jacqueline-Marie N. Ferland et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Emerging signals modulating potential of ginseng and its active compounds focusing on neurodegenerative diseases

(2018) Md. Jakaria et al.   Journal of Ginseng Research

Orphan receptor GPR158 controls stress-induced depression

(2018) Laurie P Sutton et al.   eLife

Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1 G93A transgenic mice, an experimental model of amyotrophic lateral sclerosis

(2018) Carmen Rodríguez-Cueto et al.   BIOCHEMICAL PHARMACOLOGY

Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet

(2018) Yinghua Yu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Importance of GPCR-Mediated Microglial Activation in Alzheimer’s Disease

(2018) Md. Ezazul Haque et al.   Frontiers in Cellular Neuroscience

Active ginseng components in cognitive impairment: Therapeutic potential and prospects for delivery and clinical study

(2018) Md. Jakaria et al.   Oncotarget

Neurotoxic Agent-Induced Injury in Neurodegenerative Disease Model: Focus on Involvement of Glutamate Receptors

(2018) Md. Jakaria et al.   Frontiers in Molecular Neuroscience

Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology

(2018) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection?

(2018) Simona Federica Spampinato et al.   Frontiers in Molecular Neuroscience

The impact of anorexigenic peptides in experimental models of Alzheimer’s disease pathology

(2018) Lenka Maletínská et al.   JOURNAL OF ENDOCRINOLOGY

Dopamine guides competition for cognitive control: Common effects of haloperidol on working memory and response conflict

(2018) Sean James Fallon et al.   CORTEX

A putative lysophosphatidylinositol receptor GPR55 modulates hippocampal synaptic plasticity

(2017) Katrina Hurst et al.   HIPPOCAMPUS

Gpr158 mediates osteocalcin’s regulation of cognition

(2017) Lori Khrimian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer’s Disease

(2017) Ramakrishna Nirogi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development and validation of sensitive LC–MS/MS method for the quantification of SUVN-502 and its metabolite and its application for first in human pharmacokinetic study

(2017) Ramakrishna Nirogi et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases

(2017) Lila Carniglia et al.   MEDIATORS OF INFLAMMATION

The DRD2 Taq1A A1 Allele May Magnify the Risk of Alzheimer’s in Aging African-Americans

(2017) Kenneth Blum et al.   MOLECULAR NEUROBIOLOGY

Trends in GPCR drug discovery: new agents, targets and indications

(2017) Alexander S. Hauser et al.   NATURE REVIEWS DRUG DISCOVERY

Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model

(2017) Laura Foucault-Fruchard et al.   NEUROSCIENCE

A new serotonin 5-HT6 receptor antagonist with procognitive activity – Importance of a halogen bond interaction to stabilize the binding

(2017) Juan A. González-Vera et al.   Scientific Reports

The Pathology of “Vascular Dementia”: A Critical Update

(2017) Kurt A. Jellinger   JOURNAL OF ALZHEIMERS DISEASE

Intra-Familial Clinical Heterogeneity due to FTLD-U with TDP-43 Proteinopathy Caused by a Novel Deletion in Progranulin Gene (PGRN)

(2017) Tomasz Gabryelewicz et al.   JOURNAL OF ALZHEIMERS DISEASE

Serotonin 5-HT6 Receptor Antagonists in Alzheimer’s Disease: Therapeutic Rationale and Current Development Status

(2016) Hilda Ferrero et al.   CNS DRUGS

Preclinical evaluation of AVN-322, novel and highly selective 5-HT6 receptor antagonist, for the treatment of Alzheimer's disease

(2016) Alexandre Ivachtchenko et al.   Current Alzheimer Research

Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain

(2016) Toshihiro Yanai et al.   GENES TO CELLS

AVN-101: A Multi-Target Drug Candidate for the Treatment of CNS Disorders

(2016) Alexandre V. Ivachtchenko et al.   JOURNAL OF ALZHEIMERS DISEASE

Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects

(2016) Jennifer E. Davoren et al.   JOURNAL OF MEDICINAL CHEMISTRY

The clinical symptoms of Parkinson's disease

(2016) Sigurlaug Sveinbjornsdottir   JOURNAL OF NEUROCHEMISTRY

AVN-211, Novel and Highly Selective 5-HT6 Receptor Small Molecule Antagonist, for the Treatment of Alzheimer’s Disease

(2016) Alexandre V. Ivachtchenko et al.   MOLECULAR PHARMACEUTICS

A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson's Disease

(2016) François Tison et al.   MOVEMENT DISORDERS

Crystal structures of the M1 and M4 muscarinic acetylcholine receptors

(2016) David M. Thal et al.   NATURE

Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression

(2016) Anthony A. Grace   NATURE REVIEWS NEUROSCIENCE

G-protein coupled receptors as therapeutic targets for neurodegenerative and cerebrovascular diseases

(2016) Mounia Guerram et al.   NEUROCHEMISTRY INTERNATIONAL

Agomelatine Improves Apathy in Frontotemporal Dementia

(2016) Ilaria Callegari et al.   Neurodegenerative Diseases

Dopamine Does Double Duty in Motivating Cognitive Effort

(2016) Andrew Westbrook et al.   NEURON

Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer’s disease

(2016) Iván Manuel et al.   NEUROSCIENCE

Behavioural effects of PNU-282987 and stress in an animal model of Alzheimer's disease

(2016) Paloma Vicens et al.   Psychogeriatrics

Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia

(2016) Michael R. Wood et al.   ACS Medicinal Chemistry Letters

Emerging preclinical pharmacological targets for Parkinson’s disease

(2016) Sandeep Vasant More et al.   Oncotarget

VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease

(2016) Javier Díaz-Alonso et al.   Scientific Reports

Behavioural effects of PNU-282987 and stress in an animal model of Alzheimer's disease

(2016) Paloma Vicens et al.   Psychogeriatrics

In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD

(2015) Antoine Leuzy et al.   Brain Structure & Function

Chronic treatment with a tryptophan-rich protein hydrolysate improves emotional processing, mental energy levels and reaction time in middle-aged women

(2015) M. H. Mohajeri et al.   BRITISH JOURNAL OF NUTRITION

Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

(2015) R B Laprairie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease

(2015) Brian Spencer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agomelatine for Depression in Parkinson Disease

(2015) Asuncion Avila et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Vortioxetine: a meta-analysis of 12 short-term, randomized, placebo-controlled clinical trials for the treatment of major depressive disorder

(2015) Chi-Un Pae et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Persistent effects of chronic Δ9-THC exposure on motor impulsivity in rats

(2015) Cristina Irimia et al.   PSYCHOPHARMACOLOGY

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer’s disease mouse models

(2015) Yunhong Huang et al.   Science Translational Medicine

5-HT1Breceptor imaging and cognition: A positron emission tomography study in control subjects and parkinson's disease patients

(2015) Andrea Varrone et al.   SYNAPSE

Mitochondrial protection by the mixed muscarinic/σ1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ25–35 peptide-injected mice, a nontransgenic Alzheimer’s disease model

(2015) Valentine Lahmy et al.   Frontiers in Cellular Neuroscience

Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits

(2015) Danielle A. Baribeau et al.   Frontiers in Neuroscience

Hippocampal 5-HT1A Receptor and Spatial Learning and Memory

(2015) Yifat Glikmann-Johnston et al.   Frontiers in Pharmacology

Diagnostic Criteria for Vascular Cognitive Disorders

(2014) Perminder Sachdev et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Metabotropic Glutamate Receptor 5 in Down's Syndrome Hippocampus During Development: Increased Expression in Astrocytes

(2014) A.M. Iyer et al.   Current Alzheimer Research

The 5-HT6 receptor antagonism approach in Alzheimer's disease

(2014) D. Marazziti et al.   DRUGS OF THE FUTURE

EPA-1197 – Agomelatine for treating apathy in alzheimer's disease

(2014) D. Karaiskos et al.   EUROPEAN PSYCHIATRY

Serotonin 5-HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease

(2014) Bellinda Benhamú et al.   JOURNAL OF MEDICINAL CHEMISTRY

Striatal Cholinergic Neurotransmission Requires VGLUT3

(2014) A. B. Nelson et al.   JOURNAL OF NEUROSCIENCE

Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β

(2014) Hye Rin Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Idalopirdine for Alzheimer's disease: written in the stars

(2014) Lon S Schneider   LANCET NEUROLOGY

Activation of GABAB Receptors Ameliorates Cognitive Impairment via Restoring the Balance of HCN1/HCN2 Surface Expression in the Hippocampal CA1 Area in Rats With Chronic Cerebral Hypoperfusion

(2014) Chang-jun Li et al.   MOLECULAR NEUROBIOLOGY

The neurobiological basis of cognitive impairment in Parkinson's disease

(2014) Glenda M. Halliday et al.   MOVEMENT DISORDERS

The link between multiple sclerosis and depression

(2014) Anthony Feinstein et al.   Nature Reviews Neurology

The endocannabinoid system: An emotional buffer in the modulation of memory function

(2014) Maria Morena et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

SSP-002392, a new 5-HT4 receptor agonist, dose-dependently reverses scopolamine-induced learning and memory impairments in C57Bl/6 mice

(2014) Adrian C. Lo et al.   NEUROPHARMACOLOGY

Anatomical Transcriptome of G Protein-Coupled Receptors Leads to the Identification of a Novel Therapeutic Candidate GPR52 for Psychiatric Disorders

(2014) Hidetoshi Komatsu et al.   PLoS One

Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease

(2014) Alison Hamilton et al.   Molecular Brain

α7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles

(2013) Rodrigo Medeiros et al.   AMERICAN JOURNAL OF PATHOLOGY

The therapeutics of Alzheimer's disease: Where we stand and where we are heading

(2013) Dennis J. Selkoe   ANNALS OF NEUROLOGY

The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication

(2013) Mathias Rask-Andersen et al.   Annual Review of Pharmacology and Toxicology

An overview of the diverse roles of G-protein coupled receptors (GPCRs) in the pathophysiology of various human diseases

(2013) Boon Chin Heng et al.   BIOTECHNOLOGY ADVANCES

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

(2013) Mirjana B. Colovic et al.   Current Neuropharmacology

Allosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's disease

(2013) Bruce J. Melancon et al.   DRUG DISCOVERY TODAY

Glutamate, Glutamate Receptors, and Downstream Signaling Pathways

(2013) Stacey S. Willard et al.   International Journal of Biological Sciences

Emerging paradigms in GPCR allostery: implications for drug discovery

(2013) Denise Wootten et al.   NATURE REVIEWS DRUG DISCOVERY

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

Enhancement of long-term depression by soluble amyloid β protein in rat hippocampus is mediated by metabotropic glutamate receptor and involves activation of p38MAPK, STEP and caspase-3

(2013) X. Chen et al.   NEUROSCIENCE

Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate

(2013) A Santos-Carvalho et al.   Cell Death & Disease

Frontotemporal dementia

(2013) J. D. Warren et al.   BMJ-British Medical Journal

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1

(2013) Serena Notartomaso et al.   Molecular Brain

Dopamine imbalance in Huntington's disease: a mechanism for the lack of behavioral flexibility

(2013) Jane Y. Chen et al.   Frontiers in Neuroscience

Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets

(2012) Xiao-long Tang et al.   ACTA PHARMACOLOGICA SINICA

α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation

(2012) Yuan Liu et al.   Journal of Neuroinflammation

Activation of the CB2 receptor system reverses amyloid-induced memory deficiency

(2012) Jiang Wu et al.   NEUROBIOLOGY OF AGING

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway

(2012) Gohar Fakhfouri et al.   NEUROPHARMACOLOGY

Stimulation of serotonin 2A receptors facilitates consolidation and extinction of fear memory in C57BL/6J mice

(2012) Gongliang Zhang et al.   NEUROPHARMACOLOGY

Effects of a diet integration with an oily emulsion of DHA-phospholipids containing melatonin and tryptophan in elderly patients suffering from mild cognitive impairment

(2012) Mariangela Rondanelli et al.   NUTRITIONAL NEUROSCIENCE

Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice

(2012) Caroline Sarah Biskup et al.   PLoS One

The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness

(2012) Patrizia Campolongo et al.   Frontiers in Behavioral Neuroscience

The effects of oxytocin on social cognition and behaviour in frontotemporal dementia

(2011) Sarah Jesso et al.   BRAIN

5-HT6 receptor and cognition

(2011) Xabier Codony et al.   CURRENT OPINION IN PHARMACOLOGY

GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons

(2011) Daniel F English et al.   NATURE NEUROSCIENCE

Dopamine release in the basal ganglia

(2011) M.E. Rice et al.   NEUROSCIENCE

 6 2* and  4 2* Nicotinic Acetylcholine Receptors As Drug Targets for Parkinson's Disease

(2011) M. Quik et al.   PHARMACOLOGICAL REVIEWS

The effects of PRX-07034, a novel 5-HT6 antagonist, on cognitive flexibility and working memory in rats

(2011) Eric G. Mohler et al.   PSYCHOPHARMACOLOGY

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Localisation of pre- and postsynaptic cholinergic markers in the human brain

(2010) Andrea Wevers   BEHAVIOURAL BRAIN RESEARCH

Neurodevelopmental actions of leptin

(2010) Sebastien G. Bouret   BRAIN RESEARCH

Double-Blind, Controlled Phase II Study of a 5-HT6 Receptor Antagonist, SB-742457, in Alzheimers Disease

(2010) G. Maher-Edwards et al.   Current Alzheimer Research

SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study

(2010) Gareth Maher-Edwards et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

NPY promotes chemokinesis and neurogenesis in the rat subventricular zone

(2010) Nathalie Thiriet et al.   JOURNAL OF NEUROCHEMISTRY

Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies  -Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

(2010) F. Caraci et al.   MOLECULAR PHARMACOLOGY

Mild cognitive impairment in Parkinson disease: A multicenter pooled analysis

(2010) D. Aarsland et al.   NEUROLOGY

Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5

(2010) Marianne Renner et al.   NEURON

Metabotropic glutamate receptors: From the workbench to the bedside

(2010) F. Nicoletti et al.   NEUROPHARMACOLOGY

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

Safety, tolerability and pharmacokinetics of SUVN-502 - A 5-HT 6 receptor antagonist, first in human phase-1 Single Ascending Dose (SAD) study

(2009) Ramakrishna Nirogi et al.   Alzheimers & Dementia

Increased binding to 5-HT1A and 5-HT2A receptors is associated with large vessel infarction and relative preservation of cognition

(2009) M. S. J. Elliott et al.   BRAIN

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages

(2009) Rosa María Tolón et al.   BRAIN RESEARCH

Acute citalopram administration may disrupt contextual information processing in healthy males

(2009) S. Almeida et al.   EUROPEAN PSYCHIATRY

Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease

(2009) Onintza Sagredo et al.   GLIA

Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET

(2009) H. Shimada et al.   NEUROLOGY

Effects of acute tryptophan depletion on memory, attention and executive functions: A systematic review

(2009) Daniel Mendelsohn et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

GPR3 Receptor, a Novel Actor in the Emotional-Like Responses

(2009) Olga Valverde et al.   PLoS One

Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory

(2009) P. Campolongo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Orphan G Protein-Coupled Receptor 3 Modulates Amyloid-Beta Peptide Generation in Neurons

(2009) A. Thathiah et al.   SCIENCE

Memantine for the Treatment of Alzheimer???s Disease

(2008) Martin R Farlow et al.   DRUG SAFETY

Efficacy of paroxetine in treating major depressive disorder in persons with multiple sclerosis

(2008) Dawn M. Ehde et al.   GENERAL HOSPITAL PSYCHIATRY

The effects of acute tryptophan depletion on affective behaviour and cognition in Brown Norway and Sprague Dawley rats

(2008) LAW Jans et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study

(2008) Rachelle S Doody et al.   LANCET

The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years

(2008) Mariese A. Hely et al.   MOVEMENT DISORDERS

An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function

(2008) Kevin C.F. Fone   NEUROPHARMACOLOGY

Oxytocin, Vasopressin, and the Neurogenetics of Sociality

(2008) Z. R. Donaldson et al.   SCIENCE

A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory

(2008) M KING et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo

(2007) Delphine Charvin et al.   NEUROBIOLOGY OF DISEASE