Potential Therapeutic Targets of Quercetin and Its Derivatives: Its Role in the Therapy of Cognitive Impairment
出版年份 2019 全文链接
标题
Potential Therapeutic Targets of Quercetin and Its Derivatives: Its Role in the Therapy of Cognitive Impairment
作者
关键词
-
出版物
Journal of Clinical Medicine
Volume 8, Issue 11, Pages 1789
出版商
MDPI AG
发表日期
2019-10-25
DOI
10.3390/jcm8111789
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death
- (2019) Md. Jakaria et al. MOLECULAR NEUROBIOLOGY
- Quercetin based derivatives as sirtuin inhibitors
- (2019) Vladimír Heger et al. BIOMEDICINE & PHARMACOTHERAPY
- Quercetin mitigates anxiety-like behavior and normalizes hypothalamus–pituitary–adrenal axis function in a mouse model of mild traumatic brain injury
- (2019) Morteza Kosari-Nasab et al. BEHAVIOURAL PHARMACOLOGY
- The Methanol Extract of Allium cepa L. Protects Inflammatory Markers in LPS-Induced BV-2 Microglial Cells and Upregulates the Antiapoptotic Gene and Antioxidant Enzymes in N27-A Cells
- (2019) Md. Jakaria et al. Antioxidants
- An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds
- (2018) Jonathan Fusi et al. BIOMEDICINE & PHARMACOTHERAPY
- Quercetin Potentiates the NGF-Induced Effects in Cultured PC 12 Cells: Identification by HerboChips Showing a Binding with NGF
- (2018) Gallant K. L. Chan et al. Evidence-based Complementary and Alternative Medicine
- Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production
- (2018) Hee Jo Park et al. JOURNAL OF NATURAL PRODUCTS
- Neuropharmacological Potential and Delivery Prospects of Thymoquinone for Neurological Disorders
- (2018) Md. Jakaria et al. Oxidative Medicine and Cellular Longevity
- Involvement of PKA/DARPP-32/PP1α and β- arrestin/Akt/GSK-3β Signaling in Cadmium-Induced DA-D2 Receptor-Mediated Motor Dysfunctions: Protective Role of Quercetin
- (2018) Richa Gupta et al. Scientific Reports
- Emerging signals modulating potential of ginseng and its active compounds focusing on neurodegenerative diseases
- (2018) Md. Jakaria et al. Journal of Ginseng Research
- Active ginseng components in cognitive impairment: Therapeutic potential and prospects for delivery and clinical study
- (2018) Md. Jakaria et al. Oncotarget
- Pharmacophore Screening and Docking studies of AMPA Receptor Implicated in Alzheimer’s disease with Some CNS Acting Phytocompounds from Selected Ayurvedic Medicinal Plants
- (2018) Preenon Bagchi et al. Neuropsychiatry
- Neurotoxic Agent-Induced Injury in Neurodegenerative Disease Model: Focus on Involvement of Glutamate Receptors
- (2018) Md. Jakaria et al. Frontiers in Molecular Neuroscience
- Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity
- (2018) Hui-Ran Fan et al. EBioMedicine
- Neuroprotection of quercetin on central neurons against chronic high glucose through enhancement of Nrf2/ARE/glyoxalase-1 pathway mediated by phosphorylation regulation
- (2018) Yao-Wu Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- Phytochemicals and cognitive health: Are flavonoids doing the trick?
- (2018) Ioannis Bakoyiannis et al. BIOMEDICINE & PHARMACOTHERAPY
- Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology
- (2018) Md. Sahab Uddin et al. MOLECULAR NEUROBIOLOGY
- Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways
- (2017) Entaz Bahar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease
- (2017) Muhammet Ay et al. JOURNAL OF NEUROCHEMISTRY
- Protective effect of quercetin on bupivacaine-induced neurotoxicity via T-type calcium channel inhibition
- (2017) Chao Jin et al. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
- Quercetin Improves Glucose and Lipid Metabolism of Diabetic Rats: Involvement of Akt Signaling and SIRT1
- (2017) Jing Peng et al. Journal of Diabetes Research
- Neuroprotective effects of quercetin in diabetic rat retina
- (2017) Mohammad S. Ola et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism
- (2017) Rafael Lazo-Gomez et al. Translational Neurodegeneration
- Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions
- (2016) Natarajan Suganthy et al. BIOMEDICINE & PHARMACOTHERAPY
- Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents
- (2016) Byung-Hwan Lee et al. Biomolecules & Therapeutics
- Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells
- (2016) Lenka Roubalová et al. CHEMICO-BIOLOGICAL INTERACTIONS
- The effects of quercetin on the gene expression of the GABAA receptor α5 subunit gene in a mouse model of kainic acid-induced seizure
- (2016) Sahar Moghbelinejad et al. Journal of Physiological Sciences
- Quercetin modulates toll-like receptor-mediated protein kinase signaling pathways in oxLDL-challenged human PBMCs and regulates TLR-activated atherosclerotic inflammation in hypercholesterolemic rats
- (2016) Shobha Bhaskar et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice
- (2016) Xilin Zhang et al. NEUROPHARMACOLOGY
- Quercetin attenuates domoic acid-induced cognitive deficits in mice
- (2016) Dongmei Wang et al. NUTRITIONAL NEUROSCIENCE
- Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More
- (2016) Lucio G. Costa et al. Oxidative Medicine and Cellular Longevity
- The Role of Quercetin in Gene Expression of GluR1 Subunit of AMPA Receptors, and NR2A and NR2B Subunits of NMDA Receptors in Kainic Acid Model of Seizure in Mice
- (2016) Sahar Moghbelinejad et al. Iranian Red Crescent Medical Journal
- Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation
- (2015) Ching-Hsia Hung et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Modulation of BV-2 microglia functions by novel quercetin pivaloyl ester
- (2015) Nataša Mrvová et al. NEUROCHEMISTRY INTERNATIONAL
- Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways
- (2015) Iandra Holzmann et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1
- (2015) Grace Y. Sun et al. PLoS One
- Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability
- (2015) Kyuichi Kawabata et al. Food & Function
- Enhancement of flavonoid ability to cross the blood–brain barrier of rats by co-administration with α-tocopherol
- (2015) Paola Ferri et al. Food & Function
- Antioxidant Agent Quercetin Prevents Impairment of Bladder Tissue Contractility and Apoptosis in a Rat Model of Ischemia/Reperfusion Injury
- (2015) Ilker TINAY et al. LUTS-Lower Urinary Tract Symptoms
- Estimated Daily Intake and Seasonal Food Sources of Quercetin in Japan
- (2015) Haruno Nishimuro et al. Nutrients
- Specific localization of quercetin-3-O-glucuronide in human brain
- (2014) Akari Ishisaka et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1
- (2014) Jing Dong et al. JOURNAL OF LIPID RESEARCH
- Flavonoids with M1 Muscarinic Acetylcholine Receptor Binding Activity
- (2014) Meyyammai Swaminathan et al. MOLECULES
- Loading into Nanoparticles Improves Quercetin's Efficacy in Preventing Neuroinflammation Induced by Oxysterols
- (2014) Gabriella Testa et al. PLoS One
- The Flavonoid Quercetin Reverses Pulmonary Hypertension in Rats
- (2014) Daniel Morales-Cano et al. PLoS One
- Quercetin negatively regulates TLR4 signaling induced by lipopolysaccharide through Tollip expression
- (2013) Eui-Baek Byun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sirtuin deacetylases in neurodegenerative diseases of aging
- (2013) Adrianna Z Herskovits et al. CELL RESEARCH
- Quercetin antagonism of GABAAρ1 receptors is prevented by ascorbic acid through a redox-independent mechanism
- (2013) Cecilia I. Calero et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Quercetin inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglial cells by suppressing the NF-κB pathway and activating the Nrf2-dependent HO-1 pathway
- (2013) Chang-Hee Kang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Target- and Mechanism-Based Therapeutics for Neurodegenerative Diseases: Strength in Numbers
- (2013) Paul C. Trippier et al. JOURNAL OF MEDICINAL CHEMISTRY
- Quercetin inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex
- (2013) Cheng-Wei Lu et al. NEUROTOXICOLOGY
- Ginkgo Biloba Extract and Long-Term Cognitive Decline: A 20-Year Follow-Up Population-Based Study
- (2013) Hélène Amieva et al. PLoS One
- Neuroprotective Role of Nanoencapsulated Quercetin in Combating Ischemia-Reperfusion Induced Neuronal Damage in Young and Aged Rats
- (2013) Aparajita Ghosh et al. PLoS One
- Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases
- (2012) Daniele Del Rio et al. ANTIOXIDANTS & REDOX SIGNALING
- Effect of Quercetin in the 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-Induced Mouse Model of Parkinson's Disease
- (2012) Chuanfeng Lv et al. Evidence-based Complementary and Alternative Medicine
- Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease
- (2012) Lap Ho et al. FASEB JOURNAL
- Life or death: Neuroprotective and anticancer effects of quercetin
- (2012) Federico Dajas JOURNAL OF ETHNOPHARMACOLOGY
- Quercetin Attenuates Cell Apoptosis in Focal Cerebral Ischemia Rat Brain Via Activation of BDNF–TrkB–PI3K/Akt Signaling Pathway
- (2012) Rui-Qin Yao et al. NEUROCHEMICAL RESEARCH
- Neuroprotective and Anti-Inflammatory Effects of the Flavonoid-Enriched Fraction AF4 in a Mouse Model of Hypoxic-Ischemic Brain Injury
- (2012) Paul G. W. Keddy et al. PLoS One
- Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin
- (2011) Jun-Shik Choi et al. ARCHIVES OF PHARMACAL RESEARCH
- Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs
- (2011) J. Li et al. CARCINOGENESIS
- Quercetin Stimulates NGF-induced Neurite Outgrowth in PC12 Cells via Activation of Na+/K+/2Cl- Cotransporter
- (2011) Ken-ichi Nakajima et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Cognitive-Enhancing Effect of Quercetin in a Rat Model of Parkinson's Disease Induced by 6-Hydroxydopamine
- (2011) Napatr Sriraksa et al. Evidence-based Complementary and Alternative Medicine
- Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats
- (2011) Akari Ishisaka et al. FREE RADICAL BIOLOGY AND MEDICINE
- Influence of Quercetin Supplementation on Disease Risk Factors in Community-Dwelling Adults
- (2011) Amy M. Knab et al. JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION
- Inhibitory Effects of Quercetin on Muscle-type of Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes
- (2011) Byung-Hwan Lee et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Quercetin Inhibits α3β4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed inXenopusOocytes
- (2011) Byung-Hwan Lee et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Apolipoprotein E in Alzheimer's disease and other neurological disorders
- (2011) Philip B Verghese et al. LANCET NEUROLOGY
- Neuroprotective effects of quercetin, rutin and okra (Abelmoschus esculentus Linn.) in dexamethasone-treated mice
- (2011) Walaiporn Tongjaroenbuangam et al. NEUROCHEMISTRY INTERNATIONAL
- Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum
- (2011) Nagaraja Haleagrahara et al. NEUROSCIENCE LETTERS
- Impact of apolipoprotein E genotype and dietary quercetin on paraoxonase 1 status in apoE3 and apoE4 transgenic mice
- (2010) Christine Boesch-Saadatmandi et al. ATHEROSCLEROSIS
- Effects of quercetin on α9α10 nicotinic acetylcholine receptor-mediated ion currents
- (2010) Byung-Hwan Lee et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Quercetin enhances human α7 nicotinic acetylcholine receptor-mediated ion current through interactions with Ca2+ binding sites
- (2010) Byung-Hwan Lee et al. MOLECULES AND CELLS
- Plasma Levels and Distribution of Flavonoids in Rat Brain after Single and Repeated Doses of StandardizedGinkgo bilobaExtract EGb 761®
- (2010) Laura Rangel-Ordóñez et al. PLANTA MEDICA
- Serum Lipid and Blood Pressure Responses to Quercetin Vary in Overweight Patients by Apolipoprotein E Genotype
- (2009) Sarah Egert et al. JOURNAL OF NUTRITION
- Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice
- (2009) Yan Hou et al. NEUROPHARMACOLOGY
- Quercetin improves cognitive deficits in rats with chronic cerebral ischemia and inhibits voltage-dependent sodium channels in hippocampal CA1 pyramidal neurons
- (2009) Y. Yao et al. PHYTOTHERAPY RESEARCH
- Suppressive Effects of the Flavonoids Quercetin and Luteolin on the Accumulation of Lipid Rafts after Signal Transduction via Receptors
- (2008) Masahiro Kaneko et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Flavonoid characterization and in vitro antioxidant activity of Aconitum anthora L. (Ranunculaceae)
- (2008) Cristina Mariani et al. PHYTOCHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started