Solute Carrier Transporters as Potential Targets for the Treatment of Metabolic Disease
出版年份 2019 全文链接
标题
Solute Carrier Transporters as Potential Targets for the Treatment of Metabolic Disease
作者
关键词
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出版物
PHARMACOLOGICAL REVIEWS
Volume 72, Issue 1, Pages 343-379
出版商
American Society for Pharmacology & Experimental Therapeutics (ASPET)
发表日期
2019-12-28
DOI
10.1124/pr.118.015735
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- Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets
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- A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion
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- Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice
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- Renal Gene and Protein Expression Signatures for Prediction of Kidney Disease Progression
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- Deletion of the mouseSlc30a8gene encoding zinc transporter-8 results in impaired insulin secretion
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- Enhanced tumor growth in the NaS1 sulfate transporter null mouse
- (2009) Paul Anthony Dawson et al. CANCER SCIENCE
- The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction
- (2009) Barry R Palmer et al. Cardiovascular Diabetology
- UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality
- (2009) Helena M. Feldmann et al. Cell Metabolism
- Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants
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- High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity
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- Persistent Oxidative Stress Due to Absence of Uncoupling Protein 2 Associated with Impaired Pancreatic β-Cell Function
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- Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms
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- Functional Brown Adipose Tissue in Healthy Adults
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- Cold-Activated Brown Adipose Tissue in Healthy Men
- (2009) Wouter D. van Marken Lichtenbelt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Identification and Importance of Brown Adipose Tissue in Adult Humans
- (2009) Aaron M. Cypess et al. NEW ENGLAND JOURNAL OF MEDICINE
- The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes
- (2009) J.-J. Jia et al. Obesity Reviews
- SLC30A3 Responds to Glucose- and Zinc Variations in ß-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During ß-Cell Stress
- (2009) Kamille Smidt et al. PLoS One
- Long-lived Indy and calorie restriction interact to extend life span
- (2009) P.-Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damage
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- Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice
- (2009) K. Lemaire et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations
- (2009) Melanie Kolz et al. PLoS Genetics
- Monocarboxylate transporter (MCT)-1 is up-regulated by PPARα
- (2008) Bettina König et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Increased densities of monocarboxylate transporter MCT1 after chronic hyperglycemia in rat brain
- (2008) Martin Canis et al. BRAIN RESEARCH
- The Common -866G>A Variant in the Promoter of UCP2 Is Associated With Decreased Risk of Coronary Artery Disease in Type 2 Diabetic Men
- (2008) N. Cheurfa et al. DIABETES
- Genetic Variants in the UCP2-UCP3 Gene Cluster and Risk of Diabetes in the Women's Health Initiative Observational Study
- (2008) Y.-H. Hsu et al. DIABETES
- The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients—the EUGENE2 study
- (2008) T. W. Boesgaard et al. DIABETOLOGIA
- Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1
- (2008) J.L. Bento et al. GENOMICS
- Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease
- (2008) Michiharu Komatsu et al. JOURNAL OF HEPATOLOGY
- The common −55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population
- (2008) Taku Hamada et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Effects ofUCP2andUCP3Variants on the Manifestation of Overweight in Korean Children
- (2008) H.S. Jun et al. Obesity
- Genotype-Phenotype Associations in Obesity Dependent on Definition of the Obesity Phenotype
- (2008) Sofia Inez Iqbal Kring et al. Obesity Facts
- Mutations in UCP2 in Congenital Hyperinsulinism Reveal a Role for Regulation of Insulin Secretion
- (2008) M. Mar González-Barroso et al. PLoS One
- Effect of weight loss on lactate transporter expression in skeletal muscle of obese subjects
- (2007) Lore Metz et al. JOURNAL OF APPLIED PHYSIOLOGY
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