Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel

Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes

(2016) Chengfeng Merriman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Genetic Regulation ofSlc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance

(2016) Ryan K. Mitchell et al.   MOLECULAR ENDOCRINOLOGY

Metals in Urine and Diabetes in United States Adults

(2015) Andy Menke et al.   DIABETES

Dorothy Hodgkin Lecture 2014Understanding genes identified by genome-wide association studies for Type 2 diabetes

(2014) G. A. Rutter   DIABETIC MEDICINE

SLC30A8 mutations in type 2 diabetes

(2014) Guy A. Rutter et al.   DIABETOLOGIA

Nickel exposure is associated with the prevalence of type 2 diabetes in Chinese adults

(2014) Gang Liu et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Association between urinary cadmium levels and prediabetes in the NHANES 2005–2010 population

(2014) Amisha Wallia et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Associations of Urinary Cadmium with Age and Urinary Proteins: Further Evidence of Physiological Variations Unrelated to Metal Accumulation and Toxicity

(2013) Agnes Chaumont et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance

(2013) Motoyuki Tamaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Cadmium Induces Apoptosis in Pancreatic β-Cells through a Mitochondria-Dependent Pathway: The Role of Oxidative Stress-Mediated c-Jun N-Terminal Kinase Activation

(2013) Kai-Chih Chang et al.   PLoS One

Accumulation of cadmium in insulin-producing β cells

(2013) Malek El Muayed et al.   Islets

The Human ZIP4 Transporter Has Two Distinct Binding Affinities and Mediates Transport of Multiple Transition Metals

(2012) Sagar Antala et al.   BIOCHEMISTRY

Standardized Transportation of Human Islets: An Islet Cell Resource Center Study of more than 2,000 Shipments

(2012) John S. Kaddis et al.   CELL TRANSPLANTATION

Association of lead, mercury and cadmium with diabetes in the Korean population: The Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010

(2012) S.-S. Moon   DIABETIC MEDICINE

Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review

(2012) Elizabeth A. Maull et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cadmium exposure in relation to insulin production, insulin sensitivity and type 2 diabetes: A cross-sectional and prospective study in women

(2012) Lars Barregard et al.   ENVIRONMENTAL RESEARCH

Helicobacter pylori Stores Nickel To Aid Its Host Colonization

(2012) Stéphane L. Benoit et al.   INFECTION AND IMMUNITY

Cadmium Intake and Systemic Exposure in Postmenopausal Women and Age-Matched Men Who Smoke Cigarettes

(2012) Andrea Ebert-McNeill et al.   TOXICOLOGICAL SCIENCES

Zinc transporters and their role in the pancreatic β-cell

(2012) Katleen Lemaire et al.   Journal of Diabetes Investigation

Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: A five-year follow-up

(2011) Witaya Swaddiwudhipong et al.   ENVIRONMENTAL RESEARCH

Cadmium, chromium, lead, manganese and nickel concentrations in blood of women in non-polluted areas in Japan, as determined by inductively coupled plasma-sector field-mass spectrometry

(2010) Masayuki Ikeda et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic β-cell function

(2010) Malek El Muayed et al.   JOURNAL OF ENDOCRINOLOGY

A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion

(2010) I Kim et al.   PHARMACOGENOMICS JOURNAL

Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition

(2010) Donald J. Steiner et al.   Islets

Deletion of the mouseSlc30a8gene encoding zinc transporter-8 results in impaired insulin secretion

(2009) Lynley D. Pound et al.   BIOCHEMICAL JOURNAL

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Population Toxicokinetic Modeling of Cadmium for Health Risk Assessment

(2009) Billy Amzal et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Trace and toxic element patterns in nonsmoker patients with noninsulin-dependent diabetes mellitus, impaired glucose tolerance, and fasting glucose

(2009) MuhittinA Serdar et al.   International Journal of Diabetes in Developing Countries

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cadmium, diabetes and chronic kidney disease

(2009) Joshua R. Edwards et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Predicting Type 2 Diabetes Based on Polymorphisms From Genome-Wide Association Studies: A Population-Based Study

(2008) M. van Hoek et al.   DIABETES

Common Variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE Genes Are Associated With Type 2 Diabetes and Impaired Fasting Glucose in a Chinese Han Population

(2008) Y. Wu et al.   DIABETES

Evaluation of status of toxic metals in biological samples of diabetes mellitus patients

(2008) Hassan Imran Afridi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients—the EUGENE2 study

(2008) T. W. Boesgaard et al.   DIABETOLOGIA

Investigation of Transport Mechanisms and Regulation of Intracellular Zn2+in Pancreatic α-Cells

(2008) Armen V. Gyulkhandanyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc Transporter-8 Gene (SLC30A8) Is Associated with Type 2 Diabetes in Chinese

(2008) Jie Xiang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

(2008) K. Girijashanker et al.   MOLECULAR PHARMACOLOGY

Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands

(2008) C. Murgia et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES