标题
Perivascular spaces in the brain: anatomy, physiology and pathology
作者
关键词
-
出版物
Nature Reviews Neurology
Volume 16, Issue 3, Pages 137-153
出版商
Springer Science and Business Media LLC
发表日期
2020-02-24
DOI
10.1038/s41582-020-0312-z
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia
- (2019) Lauren M. Hablitz et al. Science Advances
- The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
- (2019) Jerrah K. Holth et al. SCIENCE
- Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: A systematic review and meta-analysis
- (2019) Farah Francis et al. International Journal of Stroke
- Small vessel disease: mechanisms and clinical implications
- (2019) Joanna M Wardlaw et al. LANCET NEUROLOGY
- Enlarged basal ganglia perivascular spaces and sleep parameters. A population-based study
- (2019) Oscar H. Del Brutto et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways
- (2018) Nazira J. Albargothy et al. ACTA NEUROPATHOLOGICA
- The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future
- (2018) Benjamin A. Plog et al. Annual Review of Pathology-Mechanisms of Disease
- Understanding the role of the perivascular space in cerebral small vessel disease
- (2018) Rosalind Brown et al. CARDIOVASCULAR RESEARCH
- The Glymphatic System and Waste Clearance with Brain Aging: A Review
- (2018) Helene Benveniste et al. GERONTOLOGY
- Delayed clearance of cerebrospinal fluid tracer from entorhinal cortex in idiopathic normal pressure hydrocephalus: A glymphatic magnetic resonance imaging study
- (2018) Per K Eide et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cognitive function, disease burden and the structural connectome in systemic lupus erythematosus
- (2018) S J Wiseman et al. LUPUS
- Pericyte degeneration causes white matter dysfunction in the mouse central nervous system
- (2018) Axel Montagne et al. NATURE MEDICINE
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. Nature Reviews Neurology
- Review: Vascular dementia: clinicopathologic and genetic considerations
- (2018) H. V. Vinters et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- β-Amyloid accumulation in the human brain after one night of sleep deprivation
- (2018) Ehsan Shokri-Kojori et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden
- (2018) Stephanie R. Rainey-Smith et al. Translational Psychiatry
- A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology
- (2018) Catherine A Humphreys et al. International Journal of Stroke
- Visible Virchow-Robin Spaces on Magnetic Resonance Imaging of Alzheimer's Disease Patients and Normal Elderly from the Sunnybrook Dementia Study
- (2018) Joel Ramirez et al. JOURNAL OF ALZHEIMERS DISEASE
- Enlarged perivascular spaces and cognition
- (2018) Saima Hilal et al. NEUROLOGY
- Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering
- (2018) Lucia Ballerini et al. Scientific Reports
- Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes
- (2018) Per Kristian Eide et al. Scientific Reports
- Transcriptional network analysis of human astrocytic endfoot genes reveals region-specific associations with dementia status and tau pathology
- (2018) Matthew J. Simon et al. Scientific Reports
- Loss of perivascular aquaporin-4 in idiopathic normal pressure hydrocephalus
- (2018) Md Mahdi Hasan-Olive et al. GLIA
- Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow
- (2018) Yulu Shi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The glymphatic pathway in neurological disorders
- (2018) Martin Kaag Rasmussen et al. LANCET NEUROLOGY
- Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections
- (2018) Ruiyao Cai et al. NATURE NEUROSCIENCE
- Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
- (2018) Humberto Mestre et al. Nature Communications
- Aquaporin-4-dependent glymphatic solute transport in the rodent brain
- (2018) Humberto Mestre et al. eLife
- Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury
- (2018) Stéphanie Debette et al. JAMA Neurology
- Identification of the Upward Movement of Human CSF In Vivo and its Relation to the Brain Venous System
- (2017) Steffi Dreha-Kulaczewski et al. JOURNAL OF NEUROSCIENCE
- Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET
- (2017) Mony J. de Leon et al. JOURNAL OF NUCLEAR MEDICINE
- Hemorrhage recurrence risk factors in cerebral amyloid angiopathy: Comparative analysis of the overall small vessel disease severity score versus individual neuroimaging markers
- (2017) Gregoire Boulouis et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Cerebrospinal and interstitial fluid transport via the glymphatic pathway modeled by optimal mass transport
- (2017) Vadim Ratner et al. NEUROIMAGE
- CADASIL accelerated by acute hypotension
- (2017) Jacqueline A. Pettersen et al. NEUROLOGY
- Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow
- (2017) Karl Erik Holter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Moderate-to-severe obstructive sleep apnea is associated with cerebral small vessel disease
- (2017) Tae-Jin Song et al. SLEEP MEDICINE
- Clinical Correlates, Ethnic Differences, and Prognostic Implications of Perivascular Spaces in Transient Ischemic Attack and Ischemic Stroke
- (2017) Kui-Kai Lau et al. STROKE
- Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI
- (2017) Martina Absinta et al. eLife
- Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma
- (2017) Alex J Smith et al. eLife
- Large Perivascular Spaces Visible on Magnetic Resonance Imaging, Cerebral Small Vessel Disease Progression, and Risk of Dementia
- (2017) Jie Ding et al. JAMA Neurology
- Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains
- (2017) Douglas M. Zeppenfeld et al. JAMA Neurology
- High Degree of Dilated Virchow-Robin Spaces on MRI is Associated with Increased Risk of Dementia
- (2017) Yi-Cheng Zhu et al. JOURNAL OF ALZHEIMERS DISEASE
- Enlarged perivascular spaces are associated with the disease activity in systemic lupus erythematosus
- (2017) Mari Miyata et al. Scientific Reports
- Vascular basement membranes as pathways for the passage of fluid into and out of the brain
- (2016) Alan W. J. Morris et al. ACTA NEUROPATHOLOGICA
- Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy
- (2016) Abby Keable et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases
- (2016) Erik N. T. P. Bakker et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Paravascular channels, cisterns, and the subarachnoid space in the rat brain: A single compartment with preferential pathways
- (2016) Beatrice Bedussi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cerebral blood flow in small vessel disease: A systematic review and meta-analysis
- (2016) Yulu Shi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism
- (2016) Byung-Ju Jin et al. JOURNAL OF GENERAL PHYSIOLOGY
- Fatigue and cognitive function in systemic lupus erythematosus: associations with white matter microstructural damage. A diffusion tensor MRI study and meta-analysis
- (2016) S J Wiseman et al. LUPUS
- Cerebral Small Vessel Disease Burden Is Increased in Systemic Lupus Erythematosus
- (2016) Stewart J. Wiseman et al. STROKE
- Glymphatic solute transport does not require bulk flow
- (2016) Mahdi Asgari et al. Scientific Reports
- Prevalence of enlarged perivascular spaces in a memory clinic population
- (2015) Hye Won Beak et al. Alzheimers & Dementia
- Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
- (2015) Mitrajit Ghosh et al. ANNALS OF NEUROLOGY
- Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia
- (2015) Aiqing Chen et al. BRAIN
- Cerebral Perivascular Spaces Visible on Magnetic Resonance Imaging: Development of a Qualitative Rating Scale and its Observer Reliability
- (2015) Gillian M. Potter et al. CEREBROVASCULAR DISEASES
- A balanced view of the cerebrospinal fluid composition and functions: Focus on adult humans
- (2015) Reynold Spector et al. EXPERIMENTAL NEUROLOGY
- Ultra-fast magnetic resonance encephalography of physiological brain activity – Glymphatic pulsation mechanisms?
- (2015) Vesa Kiviniemi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
- (2015) Aleksanteri Aspelund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Effect of Body Posture on Brain Glymphatic Transport
- (2015) H. Lee et al. JOURNAL OF NEUROSCIENCE
- Inspiration Is the Major Regulator of Human CSF Flow
- (2015) S. Dreha-Kulaczewski et al. JOURNAL OF NEUROSCIENCE
- Structural and functional features of central nervous system lymphatic vessels
- (2015) Antoine Louveau et al. NATURE
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Total MRI load of cerebral small vessel disease and cognitive ability in older people
- (2015) Julie Staals et al. NEUROBIOLOGY OF AGING
- The Glymphatic System: A Beginner’s Guide
- (2015) Nadia Aalling Jessen et al. NEUROCHEMICAL RESEARCH
- Impairment of paravascular clearance pathways in the aging brain
- (2014) Benjamin T. Kress et al. ANNALS OF NEUROLOGY
- White Matter Changes in Dementia: Role of Impaired Drainage of Interstitial Fluid
- (2014) Roy O. Weller et al. BRAIN PATHOLOGY
- Dilated Perivascular Spaces in Small-Vessel Disease: A Study in CADASIL
- (2014) Ming Yao et al. CEREBROVASCULAR DISEASES
- Cerebrospinal fluid outflow along lumbar nerves and possible relevance for pain research: case report and review
- (2014) Karl Bechter et al. CROATIAN MEDICAL JOURNAL
- Subjective Cognitive Failures in Patients With Hypertension Are Related to Cognitive Performance and Cerebral Microbleeds
- (2014) Renske Uiterwijk et al. HYPERTENSION
- Visualization of Perivascular Spaces and Perforating Arteries With 7 T Magnetic Resonance Imaging
- (2014) Willem H. Bouvy et al. INVESTIGATIVE RADIOLOGY
- Circulating Inflammatory Markers Are Associated With Magnetic Resonance Imaging-Visible Perivascular Spaces But Not Directly With White Matter Hyperintensities
- (2014) Benjamin S. Aribisala et al. STROKE
- Enlarged Perivascular Spaces and Cerebral Small Vessel Disease
- (2013) Gillian M. Potter et al. International Journal of Stroke
- Brain-wide pathway for waste clearance captured by contrast-enhanced MRI
- (2013) Jeffrey J. Iliff et al. JOURNAL OF CLINICAL INVESTIGATION
- Towards the automatic computational assessment of enlarged perivascular spaces on brain magnetic resonance images: A systematic review
- (2013) Maria del C. Valdés Hernández et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain
- (2013) J. J. Iliff et al. JOURNAL OF NEUROSCIENCE
- Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer
- (2013) Lijun Yang et al. Journal of Translational Medicine
- Imaging new lesions: Enhancing our understanding of multiple sclerosis pathogenesis
- (2013) E. Fisher et al. NEUROLOGY
- White matter perivascular spaces: An MRI marker in pathology-proven cerebral amyloid angiopathy?
- (2013) A. Charidimou et al. NEUROLOGY
- Sleep Drives Metabolite Clearance from the Adult Brain
- (2013) L. Xie et al. SCIENCE
- Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain
- (2013) Vinita Rangroo Thrane et al. Scientific Reports
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy
- (2011) Cheryl A. Hawkes et al. ACTA NEUROPATHOLOGICA
- Assessment of the Virchow-Robin Spaces in Alzheimer Disease, Mild Cognitive Impairment, and Normal Aging, Using High-Field MR Imaging
- (2011) W. Chen et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Frequency and Location of Dilated Virchow-Robin Spaces in Elderly People: A Population-Based 3D MR Imaging Study
- (2011) Y.-C. Zhu et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- COL4A1 Mutations as a Monogenic Cause of Cerebral Small Vessel Disease
- (2010) Silvia Lanfranconi et al. STROKE
- Severity of Dilated Virchow-Robin Spaces Is Associated With Age, Blood Pressure, and MRI Markers of Small Vessel Disease
- (2010) Yi-Cheng Zhu et al. STROKE
- Enlarged Perivascular Spaces on MRI Are a Feature of Cerebral Small Vessel Disease
- (2010) Fergus N. Doubal et al. STROKE
- Lacunar stroke is associated with diffuse blood-brain barrier dysfunction
- (2009) Joanna M. Wardlaw et al. ANNALS OF NEUROLOGY
- Lymphatic drainage of the brain and the pathophysiology of neurological disease
- (2008) Roy O. Weller et al. ACTA NEUROPATHOLOGICA
- P2-010: Does variable progression of incidental white matter hyperintensities in Alzheimer's disease relate to venous insufficiency?
- (2008) Fuqiang Gao et al. Alzheimers & Dementia
- Perivascular spaces--MRI marker of inflammatory activity in the brain?
- (2008) J. Wuerfel et al. BRAIN
- apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
- (2008) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search