标题
Agonists and inhibitors of the STING pathway: Potential agents for immunotherapy
作者
关键词
-
出版物
MEDICINAL RESEARCH REVIEWS
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-12-03
DOI
10.1002/med.21649
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy
- (2019) Daniel Shae et al. Nature Nanotechnology
- Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
- (2019) Guijun Shang et al. NATURE
- Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist
- (2019) Xiaohui Zhang et al. ACS Infectious Diseases
- STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy
- (2018) David G. Leach et al. BIOMATERIALS
- SnapShot: CGAS-STING Signaling
- (2018) Lorenzo Galluzzi et al. CELL
- Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies
- (2018) Shetal A. Patel et al. IMMUNITY
- A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination
- (2018) Robert D. Junkins et al. JOURNAL OF CONTROLLED RELEASE
- Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy
- (2018) David R. Wilson et al. Nanomedicine-Nanotechnology Biology and Medicine
- STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice
- (2018) Morten K. Skouboe et al. PLoS Pathogens
- Evaluation of explant responses to STING ligands: personalized immunosurgical therapy for head and neck squamous cell carcinoma
- (2018) Jason R. Baird et al. CANCER RESEARCH
- Targeting STING with cyclic di-GMP greatly augmented immune responses of glycopeptide cancer vaccines
- (2018) Jun-Jun Wu et al. CHEMICAL COMMUNICATIONS
- Identification of α-Mangostin as an Agonist of Human STING
- (2018) Yibo Zhang et al. ChemMedChem
- Induction of necrotic cell death and activation of STING in the tumor microenvironment via cationic silica nanoparticles leading to enhanced antitumor immunity
- (2018) Myunggi An et al. Nanoscale
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling
- (2018) Anne Louise Hansen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unlocking P(V): Reagents for chiral phosphorothioate synthesis
- (2018) Kyle W. Knouse et al. SCIENCE
- Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists
- (2018) Michael A. Collier et al. MOLECULAR PHARMACEUTICS
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
- (2018) Derin B. Keskin et al. NATURE
- Design of amidobenzimidazole STING receptor agonists with systemic activity
- (2018) Joshi M. Ramanjulu et al. NATURE
- Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING
- (2018) Tony Siu et al. ACS Medicinal Chemistry Letters
- Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
- (2018) Kelsey E. Sivick et al. Cell Reports
- The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING
- (2018) Senlin Li et al. Cell Reports
- Fluorinated nucleosides as an important class of anticancer and antiviral agents
- (2017) Alessandra Cavaliere et al. Future Medicinal Chemistry
- Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors
- (2017) Tyrel T. Smith et al. JOURNAL OF CLINICAL INVESTIGATION
- Innate Immune Activation by cGMP-AMP Nanoparticles Leads to Potent and Long-Acting Antiretroviral Response against HIV-1
- (2017) Chukwuemika Aroh et al. JOURNAL OF IMMUNOLOGY
- Synthesis of All Possible Canonical (3′–5′-Linked) Cyclic Dinucleotides and Evaluation of Riboswitch Interactions and Immune-Stimulatory Effects
- (2017) Changhao Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- A STING-activating nanovaccine for cancer immunotherapy
- (2017) Min Luo et al. Nature Nanotechnology
- cGAS is essential for the antitumor effect of immune checkpoint blockade
- (2017) Hua Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Signalling strength determines proapoptotic functions of STING
- (2017) Muhammet F. Gulen et al. Nature Communications
- Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity
- (2017) Casey R. Ager et al. Cancer Immunology Research
- A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice
- (2017) Jeremy B. Foote et al. Cancer Immunology Research
- Design, Synthesis, and Biological Evaluation of Novel Cyclic Adenosine–Inosine Monophosphate (cAIMP) Analogs That Activate Stimulator of Interferon Genes (STING)
- (2016) Thierry Lioux et al. JOURNAL OF MEDICINAL CHEMISTRY
- Triggering Intracellular Receptors for Vaccine Adjuvantation
- (2016) Alice Gutjahr et al. TRENDS IN IMMUNOLOGY
- Activation of STING requires palmitoylation at the Golgi
- (2016) Kojiro Mukai et al. Nature Communications
- Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response
- (2016) Tiejun Li et al. Scientific Reports
- STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia
- (2016) Emily Curran et al. Cell Reports
- Established T Cell-Inflamed Tumors Rejected after Adaptive Resistance Was Reversed by Combination STING Activation and PD-1 Pathway Blockade
- (2016) E. Moore et al. Cancer Immunology Research
- STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice
- (2015) Zili Wang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors
- (2015) J. R. Baird et al. CANCER RESEARCH
- From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy
- (2015) L. Deng et al. CLINICAL CANCER RESEARCH
- TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
- (2015) Burcu Temizoz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Enhanced immunostimulatory activity of cyclic dinucleotides on mouse cells when complexed with a cell-penetrating peptide or combined with CpG
- (2015) Soner Yildiz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Human Disease Phenotypes Associated With Mutations in TREX1
- (2015) Gillian I. Rice et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
- (2015) Melissa C. Hanson et al. JOURNAL OF CLINICAL INVESTIGATION
- Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma
- (2015) Takashi Nakamura et al. JOURNAL OF CONTROLLED RELEASE
- STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
- (2015) Olivier Demaria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
- (2014) Nadia Jeremiah et al. JOURNAL OF CLINICAL INVESTIGATION
- Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
- (2014) Lingyin Li et al. Nature Chemical Biology
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- DMXAA Causes Tumor Site-Specific Vascular Disruption in Murine Non-Small Cell Lung Cancer, and like the Endogenous Non-Canonical Cyclic Dinucleotide STING Agonist, 2′3′-cGAMP, Induces M2 Macrophage Repolarization
- (2014) Charlene M. Downey et al. PLoS One
- Conformational restriction of cyclic dinucleotides with triazole-linked cyclophane analogues
- (2014) Tomoko Fujino et al. TETRAHEDRON LETTERS
- STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment
- (2014) T. Ohkuri et al. Cancer Immunology Research
- STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer
- (2014) D. Chandra et al. Cancer Immunology Research
- Anticancer Flavonoids Are Mouse-Selective STING Agonists
- (2013) Sujeong Kim et al. ACS Chemical Biology
- Potent suppression of c-di-GMP synthesis via I-site allosteric inhibition of diguanylate cyclases with 2′-F-c-di-GMP
- (2013) Jie Zhou et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Cyclic Dinucleotides and the Innate Immune Response
- (2013) Olga Danilchanka et al. CELL
- (3′-5′)-Cyclic Dinucleotides: Synthetic Strategies and Biological Potential
- (2013) Pascale Clivio et al. CHEMICAL REVIEWS
- Species-specific detection of the antiviral small-molecule compound CMA by STING
- (2013) Taner Cavlar et al. EMBO JOURNAL
- Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
- (2013) U. Romling et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Synthesis of c-di-GMP Analogs with Thiourea, Urea, Carbodiimide, and Guanidinium Linkages
- (2013) Barbara L. Gaffney et al. ORGANIC LETTERS
- Single Nucleotide Polymorphisms of Human STING Can Affect Innate Immune Response to Cyclic Dinucleotides
- (2013) Guanghui Yi et al. PLoS One
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Coordinated Regulation of Accessory Genetic Elements Produces Cyclic Di-Nucleotides for V. cholerae Virulence
- (2012) Bryan W. Davies et al. CELL
- Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
- (2012) Alevtina Gall et al. IMMUNITY
- Conjugated Linoleic Acid Is a Preferential Substrate for Fatty Acid Nitration
- (2012) Gustavo Bonacci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Randomized Phase III Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the Vascular Disrupting Agent Vadimezan (ASA404) in Advanced Non–Small-Cell Lung Cancer
- (2011) Primo N. Lara et al. JOURNAL OF CLINICAL ONCOLOGY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- One-Flask Syntheses of c-di-GMP and the [Rp,Rp] and [Rp,Sp] Thiophosphate Analogues
- (2010) Barbara L. Gaffney et al. ORGANIC LETTERS
- c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response
- (2010) J. J. Woodward et al. SCIENCE
- A simple solid-phase synthesis of the ubiquitous bacterial signaling molecule, c-di-GMP and analogues
- (2008) Irene Kiburu et al. Molecular BioSystems
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now