标题
The vital role of ATP citrate lyase in chronic diseases
作者
关键词
-
出版物
JOURNAL OF MOLECULAR MEDICINE-JMM
Volume 98, Issue 1, Pages 71-95
出版商
Springer Science and Business Media LLC
发表日期
2019-12-20
DOI
10.1007/s00109-019-01863-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis
- (2019) Alessandro Carrer et al. Cancer Discovery
- Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication
- (2019) Chin-Yap Loh et al. Frontiers in Oncology
- FBXW7 in Cancer: What Has Been Unraveled Thus Far?
- (2019) Bethsebie Lalduhsaki Sailo et al. Cancers
- Mendelian Randomization Study of ACLY and Cardiovascular Disease
- (2019) Brian A. Ference et al. NEW ENGLAND JOURNAL OF MEDICINE
- ATP-citrate lyase multimerization is required for coenzyme-A substrate binding and catalysis
- (2019) Gleb A. Bazilevsky et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting autophagy using natural compounds for cancer prevention and therapy
- (2019) Shuo Deng et al. CANCER
- A role for ATP Citrate Lyase in cell cycle regulation during myeloid differentiation
- (2019) Jess Rhee et al. BLOOD CELLS MOLECULES AND DISEASES
- Cancer drug development: The missing links
- (2019) Ajaikumar B Kunnumakkara et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle
- (2019) Koen H. G. Verschueren et al. NATURE
- An allosteric mechanism for potent inhibition of human ATP-citrate lyase
- (2019) Jia Wei et al. NATURE
- Depletion of ATP-Citrate Lyase (ATPCL) Affects Chromosome Integrity Without Altering Histone Acetylation in Drosophila Mitotic Cells
- (2019) Patrizia Morciano et al. Frontiers in Physiology
- Focus on Formononetin: Anticancer Potential and Molecular Targets
- (2019) Ong et al. Cancers
- Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets
- (2019) Kishore Banik et al. PHARMACOLOGICAL RESEARCH
- Metformin and AMP Kinase Activation Increase Expression of the Sterol Transporters ABCG5/8 (ATP-Binding Cassette Transporter G5/G8) With Potential Antiatherogenic ConsequencesHighlights
- (2018) Matthew M. Molusky et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Diabetes and hepatocellular carcinoma: A pathophysiological link and pharmacological management
- (2018) Mandeep Kumar Singh et al. BIOMEDICINE & PHARMACOTHERAPY
- A preclinical overview of metformin for the treatment of type 2 diabetes
- (2018) Tingting Zhou et al. BIOMEDICINE & PHARMACOTHERAPY
- Epistructured catechins, EGCG and EC facilitate apoptosis induction through targeting de novo lipogenesis pathway in HepG2 cells
- (2018) Phuriwat Khiewkamrop et al. Cancer Cell International
- Molecular targets and anti-cancer potential of escin
- (2018) Dorothy H.J. Cheong et al. CANCER LETTERS
- Therapeutic potential of gambogic acid, a caged xanthone, to target cancer
- (2018) Kishore Banik et al. CANCER LETTERS
- Triple negative breast cancer in Asia: An insider’s view
- (2018) Chao Wang et al. CANCER TREATMENT REVIEWS
- Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism
- (2018) Krishna B Singh et al. CARCINOGENESIS
- Bempedoic Acid (ETC-1002)
- (2018) Nicole K. Zagelbaum et al. Cardiology in Review
- The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase
- (2018) Phillip J. White et al. Cell Metabolism
- Metabolic routes in inflammation: the citrate pathway and its potential as therapeutic target
- (2018) Vittoria Infantino et al. CURRENT MEDICINAL CHEMISTRY
- Chronic diseases, inflammation, and spices: how are they linked?
- (2018) Ajaikumar B. Kunnumakkara et al. Journal of Translational Medicine
- Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention
- (2018) Devesh Tewari et al. PHARMACOLOGICAL RESEARCH
- Potential role of genipin in cancer therapy
- (2018) Muthu K. Shanmugam et al. PHARMACOLOGICAL RESEARCH
- Possible use of Punica granatum (Pomegranate) in cancer therapy
- (2018) Amrita Devi Khwairakpam et al. PHARMACOLOGICAL RESEARCH
- Tocotrienols: The promising analogues of vitamin E for cancer therapeutics
- (2018) Bethsebie Lalduhsaki Sailo et al. PHARMACOLOGICAL RESEARCH
- ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics
- (2018) Haisen Li et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review
- (2018) Gautam Sethi et al. Nutrients
- ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism
- (2018) Carlotta Granchi EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer
- (2018) Abhishek Ranaware et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sorcin a Potential Molecular Target for Cancer Therapy
- (2018) Bano Shabnam et al. Translational Oncology
- Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases
- (2018) Ajaikumar B. Kunnumakkara et al. Frontiers in Pharmacology
- Role of tumor-derived exosomes in cancer metastasis
- (2018) Ian Wee et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM2.5-induced epithelial-mesenchymal transition
- (2018) You Fu et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Molecular Targets Modulated by Fangchinoline in Tumor Cells and Preclinical Models
- (2018) Myriam Mérarchi et al. MOLECULES
- Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol
- (2018) Young Jung et al. MOLECULES
- Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase
- (2018) Dmitry Namgaladze et al. Frontiers in Immunology
- Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model
- (2018) Min-Yu Chung et al. Molecular Metabolism
- Potential application of zerumbone in the prevention and therapy of chronic human diseases
- (2018) Yogendra Prakash Singh et al. Journal of Functional Foods
- Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase
- (2017) Steffi K. Koerner et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Caffeic Acid Expands Anti-Tumor Effect of Metformin in Human Metastatic Cervical Carcinoma HTB-34 Cells: Implications of AMPK Activation and Impairment of Fatty Acids De Novo Biosynthesis
- (2017) Malgorzata Tyszka-Czochara et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of Resveratrol in Cancer Therapy
- (2017) Jeong-Hyeon Ko et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells
- (2017) Zhihui Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels
- (2017) Alessandro Carrer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells
- (2017) Huifen Xu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination
- (2017) Sharanya Sivanand et al. MOLECULAR CELL
- Dual role of autophagy in hallmarks of cancer
- (2017) Shikha Satendra Singh et al. ONCOGENE
- miR-133b acts as a tumor suppressor and negatively regulates ATP citrate lyase via PPARγ in gastric cancer
- (2017) Yunsheng Cheng et al. ONCOLOGY REPORTS
- Targeting ATP-Citrate Lyase in Hyperlipidemia and Metabolic Disorders
- (2017) Stephen L. Pinkosky et al. TRENDS IN MOLECULAR MEDICINE
- ATP citrate lyase is increased in human breast cancer, depletion of which promotes apoptosis
- (2017) Diyu Wang et al. TUMOR BIOLOGY
- Cell surface GRP78 promotes tumor cell histone acetylation through metabolic reprogramming: a mechanism which modulates the Warburg effect
- (2017) Udhayakumar Gopal et al. Oncotarget
- Human hepatic gene expression signature of non-alcoholic fatty liver disease progression, a meta-analysis
- (2017) Maria Ryaboshapkina et al. Scientific Reports
- ATP Citrate Lyase Regulates Myofiber Differentiation and Increases Regeneration by Altering Histone Acetylation
- (2017) Suman Das et al. Cell Reports
- Binding of hydroxycitrate to human ATP-citrate lyase
- (2017) Jinhong Hu et al. Acta Crystallographica Section D-Structural Biology
- Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells
- (2016) Ayasa Tajima et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice
- (2016) João G. B. Leandro et al. BRITISH JOURNAL OF NUTRITION
- Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance
- (2016) Federico Pietrocola et al. CANCER CELL
- Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
- (2016) Kimberly S. Lucenay et al. CANCER RESEARCH
- Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase
- (2016) Ozlem Bilen et al. Current Atherosclerosis Reports
- The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target
- (2016) Icard Philippe et al. DRUG RESISTANCE UPDATES
- Cullin3–KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression
- (2016) Cen Zhang et al. GENES & DEVELOPMENT
- Increased glycogen synthase kinase-3β and hexose-6-phosphate dehydrogenase expression in adipose tissue may contribute to glucocorticoid-induced mouse visceral adiposity
- (2016) C Yan et al. INTERNATIONAL JOURNAL OF OBESITY
- Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure
- (2016) Heather M. Wilkins et al. JOURNAL OF NEUROCHEMISTRY
- ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae
- (2016) Sarah Rodriguez et al. Microbial Cell Factories
- The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis
- (2016) G Li et al. ONCOGENE
- Sleeping Beautyscreen revealsPpargactivation in metastatic prostate cancer
- (2016) Imran Ahmad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potential of neem ( Azadirachta indica L.) for prevention and treatment of oncologic diseases
- (2016) Shradha M. Patel et al. SEMINARS IN CANCER BIOLOGY
- Bioactive natural products in cancer prevention and therapy: Progress and promise
- (2016) Anupam Bishayee et al. SEMINARS IN CANCER BIOLOGY
- Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds
- (2016) Muthu K Shanmugam et al. SEMINARS IN CANCER BIOLOGY
- Targeting arachidonic acid pathway by natural products for cancer prevention and therapy
- (2016) Nagendra Sastry Yarla et al. SEMINARS IN CANCER BIOLOGY
- Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma
- (2016) Supritha G. Swamy et al. Targeted Oncology
- Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
- (2016) Stephen L. Pinkosky et al. Nature Communications
- Amplification of USP13 drives ovarian cancer metabolism
- (2016) Cecil Han et al. Nature Communications
- Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism
- (2016) Supriya Shah et al. Oncotarget
- ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
- (2016) Steven Zhao et al. Cell Reports
- Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretion
- (2016) Mahmoud El Azzouny et al. Molecular Metabolism
- MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancers
- (2016) Pannapa Pinweha et al. Computational and Structural Biotechnology Journal
- Targeting Mitochondrial Citrate Transport in Breast Cancer Cell Lines
- (2015) Ali Ozkaya et al. Anti-Cancer Agents in Medicinal Chemistry
- Silymarin and hepatocellular carcinoma
- (2015) Jeanetta K. Mastron et al. ANTI-CANCER DRUGS
- Polymorphisms in Genes of the De Novo Lipogenesis Pathway and Overall Survival of Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolization
- (2015) You-Sheng Wu et al. Asian Pacific Journal of Cancer Prevention
- Analysis of ATP-citrate lyase and malic enzyme mutants of Yarrowia lipolytica points out the importance of mannitol metabolism in fatty acid synthesis
- (2015) Thierry Dulermo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Signalling mechanisms regulating phenotypic changes in breast cancer cells
- (2015) Natalia Volinsky et al. BIOSCIENCE REPORTS
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- ATP Citrate Lyase Improves Mitochondrial Function in Skeletal Muscle
- (2015) Suman Das et al. Cell Metabolism
- Citrate modulates lipopolysaccharide-induced monocyte inflammatory responses
- (2015) M. J. Ashbrook et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- ATP Citrate Lyase (ACLY): A Promising Target for Cancer Prevention and Treatment
- (2015) Amrita Khwairakpam et al. CURRENT DRUG TARGETS
- New targets to treat obesity and the metabolic syndrome
- (2015) Kathleen A. Martin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy
- (2015) Xiaoyun Dai et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma
- (2015) Hong Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Activated α2-Macroglobulin Binding to Human Prostate Cancer Cells Triggers Insulin-like Responses
- (2015) Uma Kant Misra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adenosine triphosphate citrate lyase: Emerging target in the treatment of dyslipidemia
- (2015) Hernán N. Lemus et al. Journal of Clinical Lipidology
- Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease
- (2015) Savannah Tallino et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance
- (2015) Carolina Gutierrez-Repiso et al. LABORATORY INVESTIGATION
- Prognostic impact of the combination of glucose transporter 1 and ATP citrate lyase in node-negative patients with non-small lung cancer
- (2015) Jun Osugi et al. LUNG CANCER
- Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats
- (2015) Qing-Rong Pan et al. NUTRITION RESEARCH
- Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells
- (2015) C Koufaris et al. ONCOGENE
- Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer
- (2015) Shuang Xie et al. World Journal of Surgical Oncology
- The advantages of using traditional Chinese medicine as an adjunctive therapy in the whole course of cancer treatment instead of only terminal stage of cancer
- (2015) Fanghua Qi et al. BioScience Trends
- ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate
- (2015) Melissa M. Keenan et al. PLoS Genetics
- Prognostic Value of Malic Enzyme and ATP-Citrate Lyase in Non-Small Cell Lung Cancer of the Young and the Elderly
- (2015) Agnes Csanadi et al. PLoS One
- γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
- (2015) Kodappully Sivaraman Siveen et al. Oncotarget
- MicroRNA-126 Suppresses Mesothelioma Malignancy by Targeting IRS1 and Interfering with the Mitochondrial Function
- (2014) Marco Tomasetti et al. ANTIOXIDANTS & REDOX SIGNALING
- Fatty Acid Synthesis Pathway Genetic Variants and Clinical Outcome of Non-Small Cell Lung Cancer Patients after Surgery
- (2014) Xin Jin et al. Asian Pacific Journal of Cancer Prevention
- Dimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy
- (2014) Guillermo Mariño et al. Autophagy
- Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth
- (2014) Yajuan Gao et al. CANCER LETTERS
- Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation
- (2014) Joyce V. Lee et al. Cell Metabolism
- ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway
- (2014) Jong-Hyuk Lee et al. FEBS Journal
- Enhanced lipid accumulation in the yeast Yarrowia lipolytica by over-expression of ATP:citrate lyase from Mus musculus
- (2014) Huaiyuan Zhang et al. JOURNAL OF BIOTECHNOLOGY
- Activation of ATP Citrate Lyase by mTOR Signal Induces Disturbed Lipid Metabolism in Hepatitis B Virus Pre-S2 Mutant Tumorigenesis
- (2014) Chiao-Fang Teng et al. JOURNAL OF VIROLOGY
- Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA
- (2014) Ursula E Bauer et al. LANCET
- Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo
- (2014) Gautam Sethi et al. Molecular Cancer
- Hepatic Carboxylesterase 1 Is Induced by Glucose and Regulates Postprandial Glucose Levels
- (2014) Jiesi Xu et al. PLoS One
- Inhibition of ATP Citrate Lyase Induces an Anticancer Effect via Reactive Oxygen Species
- (2013) Toshiro Migita et al. AMERICAN JOURNAL OF PATHOLOGY
- ATP-citrate lyase is essential for macrophage inflammatory response
- (2013) Vittoria Infantino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cytosolic functions of MORC2 in lipogenesis and adipogenesis
- (2013) Beatriz Sánchez-Solana et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Rotenone induces reductive stress and triacylglycerol deposition in C2C12 cells
- (2013) Quan He et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells
- (2013) Toshiro Migita et al. INTERNATIONAL JOURNAL OF CANCER
- DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation
- (2013) T. Londono Gentile et al. MOLECULAR AND CELLULAR BIOLOGY
- miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression
- (2013) Fang-Ting Duan et al. Molecular Cancer
- ATP Citrate Lyase Mediates Resistance of Colorectal Cancer Cells to SN38
- (2013) Y. Zhou et al. MOLECULAR CANCER THERAPEUTICS
- Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth
- (2013) Ruiting Lin et al. MOLECULAR CELL
- Batten disease is linked to altered expression of mitochondria-related metabolic molecules
- (2013) Sunyang Kang et al. NEUROCHEMISTRY INTERNATIONAL
- Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS
- (2013) Chern Chiuh Woo et al. PLoS One
- ATP citrate lyase knockdown impacts cancer stem cells in vitro
- (2013) J-i Hanai et al. Cell Death & Disease
- ATP-citrate lyase: A mini-review
- (2012) Melanie Chypre et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- On the Catalytic Mechanism of Human ATP Citrate Lyase
- (2012) Fan Fan et al. BIOCHEMISTRY
- Acetylcholine content and viability of cholinergic neurons are influenced by the activity of protein histidine phosphatase
- (2012) Anna Eißing et al. BMC NEUROSCIENCE
- Metformin Prevents Liver Tumorigenesis by Inhibiting Pathways Driving Hepatic Lipogenesis
- (2012) K. Bhalla et al. Cancer Prevention Research
- Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer
- (2012) Y. Y. Zaytseva et al. CANCER RESEARCH
- ATP-Citrate Lyase: A Key Player in Cancer Metabolism
- (2012) N. Zaidi et al. CANCER RESEARCH
- Changes in Gene Transcription Underlying the Aberrant Citrate and Choline Metabolism in Human Prostate Cancer Samples
- (2012) H. Bertilsson et al. CLINICAL CANCER RESEARCH
- First Evidence That -Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF- B Pathway
- (2012) K. A. Manu et al. CLINICAL CANCER RESEARCH
- AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism
- (2012) Stephen L. Pinkosky et al. JOURNAL OF LIPID RESEARCH
- ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms
- (2012) N. Zaidi et al. MOLECULAR CANCER THERAPEUTICS
- Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer
- (2012) YU WANG et al. ONCOLOGY REPORTS
- ATP Citrate Lyase Inhibitors as Novel Cancer Therapeutic Agents
- (2012) Xu-Yu Zu et al. Recent Patents on Anti-Cancer Drug Discovery
- Potential predictive biomarkers of obesity in Burmese cats
- (2012) Peter Lee et al. VETERINARY JOURNAL
- Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model
- (2011) Muthu K. Shanmugam et al. INTERNATIONAL JOURNAL OF CANCER
- Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1
- (2011) Peramaiyan Rajendran et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein Kinase (MAPK) and Phosphatidylinositol-3-kinase (PI3K)/AKT pathways
- (2011) Jun-ichi Hanai et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Lipogenesis Pathway as a Cancer Target
- (2011) Hanley N. Abramson JOURNAL OF MEDICINAL CHEMISTRY
- Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer
- (2011) Muthu Shanmugam et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Adipose Tissue Deficiency and Chronic Inflammation in Diabetic Goto-Kakizaki Rats
- (2011) Bai Xue et al. PLoS One
- Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic β-cells
- (2010) Vasudeva Kamath et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: Knockdown of SCOT inhibits insulin release in rat insulinoma cells
- (2010) Noaman M. Hasan et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells
- (2010) Angeline Wei Ling Chua et al. BIOCHEMICAL PHARMACOLOGY
- γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent
- (2010) Peramaiyan Rajendran et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Phosphoinositide 3-Kinase Inhibitor PI-103 Downregulates Choline Kinase Leading to Phosphocholine and Total Choline Decrease Detected by Magnetic Resonance Spectroscopy
- (2010) N. M. S. Al-Saffar et al. CANCER RESEARCH
- Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report
- (2010) Adeline Guais et al. INVESTIGATIONAL NEW DRUGS
- Identification of the Citrate-binding Site of Human ATP-Citrate Lyase Using X-ray Crystallography
- (2010) Tianjun Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ATP-Citrate Lyase Reduction Mediates Palmitate-induced Apoptosis in Pancreatic Beta Cells
- (2010) Kwan Yi Chu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of tetrazanbigen on the protein expression in human hepatocellular carcinoma cell line QGY-7701
- (2010) Yonghua Yuan et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice
- (2010) Qiong Wang et al. JOURNAL OF LIPID RESEARCH
- A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: Preliminary results
- (2010) Schwartz ONCOLOGY REPORTS
- De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy
- (2009) T Mashima et al. BRITISH JOURNAL OF CANCER
- Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
- (2009) M. J. MacDonald et al. DIABETOLOGIA
- A novel direct homogeneous assay for ATP citrate lyase
- (2009) Zhengping Ma et al. JOURNAL OF LIPID RESEARCH
- Leptin Contributes to the Adaptive Responses of Mice to High-Fat Diet Intake through Suppressing the Lipogenic Pathway
- (2009) Lei Jiang et al. PLoS One
- A Glucose-to-Gene Link
- (2009) J. C. Rathmell et al. SCIENCE
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- Chronic Diseases in Developing Countries
- (2008) Rachel Nugent Annals of the New York Academy of Sciences
- Studies with leucine, β-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion
- (2008) M MACDONALD et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer
- (2008) T. Migita et al. CANCER RESEARCH
- Clinical-Translational Approaches to the Nm23-H1 Metastasis Suppressor
- (2008) P. S. Steeg et al. CLINICAL CANCER RESEARCH
- The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis
- (2008) Shusheng Wang et al. DEVELOPMENTAL CELL
- Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice
- (2008) Qiong Wang et al. HEPATOLOGY
- Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-κB ligand through modulation of NF-κB pathway
- (2008) Kwang Seok Ahn et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of Fatty-acid Synthase Induces Caspase-8-mediated Tumor Cell Apoptosis by Up-regulating DDIT4
- (2008) Lynn M. Knowles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-κB pathway
- (2007) Kwang Seok Ahn et al. BIOCHEMICAL PHARMACOLOGY
- Construction of a chromosome 17 transcriptome in serous ovarian cancer identifies differentially expressed genes
- (2007) P.M. WOJNAROWICZ et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started