Therapeutic administration of the recombinant antimicrobial peptide microcin J25 effectively enhances host defenses against gut inflammation and epithelial barrier injury induced by enterotoxigenic Escherichia coli infection

Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract

(2019) Markus Furter et al.   Cell Reports

Flaxseed Oil Attenuates Intestinal Damage and Inflammation by Regulating Necroptosis and TLR4/NOD Signaling Pathways Following Lipopolysaccharide Challenge in a Piglet Model

(2018) Huiling Zhu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Yeast-Based Synthetic Biology Platform for Antimicrobial Peptide Production

(2018) Jicong Cao et al.   ACS Synthetic Biology

Protective Ability of Biogenic Antimicrobial Peptide Microcin J25 Against Enterotoxigenic Escherichia Coli-Induced Intestinal Epithelial Dysfunction and Inflammatory Responses IPEC-J2 Cells

(2018) Haitao Yu et al.   Frontiers in Cellular and Infection Microbiology

Attribution of Malnutrition to Cause-Specific Diarrheal Illness: Evidence from a Prospective Study of Preschool Children in Mirpur, Dhaka, Bangladesh

(2018) Dinesh Mondal et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Global Etiology of Travelers’ Diarrhea: Systematic Review from 1973 to the Present

(2018) Nipam Shah et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Risks Related to High-Dosage Recombinant Antimicrobial Peptide Microcin J25 in Mice Model: Intestinal Microbiota, Intestinal Barrier Function, and Immune Regulation

(2018) Haitao Yu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host

(2017) Qi Sam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Use of the Antimicrobial Peptide Sublancin with Combined Antibacterial and Immunomodulatory Activities To Protect against Methicillin-Resistant Staphylococcus aureus Infection in Mice

(2017) Shuai Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary supplemented antimicrobial peptide microcin J25 improves the growth performance, apparent total tract digestibility, fecal microbiota, and intestinal barrier function of weaned pigs1,2

(2017) H.T. Yu et al.   JOURNAL OF ANIMAL SCIENCE

Cathelicidin-WA Improves Intestinal Epithelial Barrier Function and Enhances Host Defense against EnterohemorrhagicEscherichia coliO157:H7 Infection

(2017) Hongbo Yi et al.   JOURNAL OF IMMUNOLOGY

Characterization of Chicken IgY Specific to Clostridium difficile R20291 Spores and the Effect of Oral Administration in Mouse Models of Initiation and Recurrent Disease

(2017) Marjorie Pizarro-Guajardo et al.   Frontiers in Cellular and Infection Microbiology

Antimicrobial Probiotics Reduce Salmonella enterica in Turkey Gastrointestinal Tracts

(2017) Brittany Forkus et al.   Scientific Reports

Porcine lactoferrin-derived peptide LFP-20 protects intestinal barrier by maintaining tight junction complex and modulating inflammatory response

(2016) Xin Zong et al.   BIOCHEMICAL PHARMACOLOGY

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Protective Capacity of Resveratrol, a Natural Polyphenolic Compound, against Deoxynivalenol-Induced Intestinal Barrier Dysfunction and Bacterial Translocation

(2016) Ka-Ho Ling et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Recombinant expression of porcine lactoferrin peptide LF-6 with intein technology and its immunomodulatory function in ETEC K88-infected mice

(2016) Qin Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Long noncoding RNA SPRY4-IT1 regulates intestinal epithelial barrier function by modulating the expression levels of tight junction proteins

(2016) Lan Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

Microcins mediate competition among Enterobacteriaceae in the inflamed gut

(2016) Martina Sassone-Corsi et al.   NATURE

Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cells

(2016) Yunpeng Wu et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health

(2016) David Ríos-Covián et al.   Frontiers in Microbiology

High therapeutic efficacy of Cathelicidin-WA against postweaning diarrhea via inhibiting inflammation and enhancing epithelial barrier in the intestine

(2016) Hongbo Yi et al.   Scientific Reports

Mo1768 Western Diet Reduces Short-Chain Fatty Acids Production and G-Protein-Coupled Receptor GPR43 Expression Promoting Intestinal Inflammation and Host Susceptibilty to E. Coli Infection

(2015) Allison Agus et al.   GASTROENTEROLOGY

The antimicrobial peptide sublancin ameliorates necrotic enteritis induced by Clostridium perfringens in broilers12

(2015) S. Wang et al.   JOURNAL OF ANIMAL SCIENCE

Inflammatory Bowel Disease and the Risk of Autoimmune Diseases

(2015) J. Claire Wilson et al.   Journal of Crohns & Colitis

Porcine β-Defensin 2 Attenuates Inflammation and Mucosal Lesions in Dextran Sodium Sulfate–Induced Colitis

(2015) Feifei Han et al.   JOURNAL OF IMMUNOLOGY

The antimicrobial peptide cathelicidin-BF could be a potential therapeutic for Salmonella typhimurium infection

(2015) Xi Xia et al.   MICROBIOLOGICAL RESEARCH

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

Antibiotic-Induced Alterations of the Murine Gut Microbiota and Subsequent Effects on Colonization Resistance against Clostridium difficile

(2015) Alyxandria M. Schubert et al.   mBio

A bioinspired peptide scaffold with high antibiotic activity and low in vivo toxicity

(2015) Francesc Rabanal et al.   Scientific Reports

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

The MAL-ED Study: A Multinational and Multidisciplinary Approach to Understand the Relationship Between Enteric Pathogens, Malnutrition, Gut Physiology, Physical Growth, Cognitive Development, and Immune Responses in Infants and Children Up to 2 Years of Age in Resource-Poor Environments

(2014) et al.   CLINICAL INFECTIOUS DISEASES

Pregnane X Receptor as the “Sensor and Effector” in Regulating Epigenome

(2014) Xi Ma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Human Cathelicidin LL-37 Host Defense Peptide Upregulates Tight Junction-Related Proteins and Increases Human Epidermal Keratinocyte Barrier Function

(2014) Toshihiro Akiyama et al.   Journal of Innate Immunity

Host Defense (Antimicrobial) Peptide, Human β-Defensin-3, Improves the Function of the Epithelial Tight-Junction Barrier in Human Keratinocytes

(2014) Chanisa Kiatsurayanon et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mouse intestinal innate immune responses altered by enterotoxigenic Escherichia coli (ETEC) infection

(2014) Wenkai Ren et al.   MICROBES AND INFECTION

Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene

(2014) Rana Al-Sadi et al.   PLoS One

Role of the enteric microbiota in intestinal homeostasis and inflammation

(2013) Iurii Koboziev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Butyrate promotes the recovering of intestinal wound healing through its positive effect on the tight junctions1

(2013) X. Ma et al.   JOURNAL OF ANIMAL SCIENCE

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Global burden of childhood pneumonia and diarrhoea

(2013) Christa L Fischer Walker et al.   LANCET

Impact of Antibiotic MIC on Infection Outcome in Patients with Susceptible Gram-Negative Bacteria: a Systematic Review and Meta-Analysis

(2012) Matthew E. Falagas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotics in early life alter the murine colonic microbiome and adiposity

(2012) Ilseung Cho et al.   NATURE

Effects of the antimicrobial peptide cecropin AD on performance and intestinal health in weaned piglets challenged with Escherichia coli

(2012) Shudan Wu et al.   PEPTIDES

Epidemiology and Natural History of Inflammatory Bowel Diseases

(2011) Jacques Cosnes et al.   GASTROENTEROLOGY

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to ExacerbatedCitrobacter rodentium-Induced Colitis

(2011) M. Wlodarska et al.   INFECTION AND IMMUNITY

Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium

(2011) Takuya Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses

(2011) K. L. Brown et al.   JOURNAL OF IMMUNOLOGY

Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components

(2011) Dulantha Ulluwishewa et al.   JOURNAL OF NUTRITION

Novel and established intestinal cell line models – An indispensable tool in food science and nutrition

(2011) Tomaz Langerholc et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Adaptive immunity in the host–microbiota dialog

(2010) T Feng et al.   Mucosal Immunology

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Host immune response to antibiotic perturbation of the microbiota

(2009) M Wlodarska et al.   Mucosal Immunology

CYTOKINE-INDUCED EPITHELIAL PERMEABILITY CHANGES ARE REGULATED BY THE ACTIVATION OF THE p38 MITOGEN-ACTIVATED PROTEIN KINASE PATHWAY IN CULTURED CACO-2 CELLS

(2009) Quan Wang et al.   SHOCK

Disruption of transepithelial resistance by enterotoxigenic Escherichia coli

(2009) Amber M. Johnson et al.   VETERINARY MICROBIOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

(2008) Katharina Brandl et al.   NATURE