A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics by Pd-Catalyzed C–H Alkynylation

(2019) Shuo Zhang et al.   ACS Catalysis

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Kinetic Resolution by Enantioselective Aromatization: Conversion of Racemic Intermediates of the Barton-Zard Reaction into Enantioenriched 3-Arylpyrroles

(2019) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric (4+3) Cyclizations of In Situ Generated ortho -Quinone Methides with 2-Indolylmethanols

(2019) Meng Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Barton–Zard Reaction To Access 3-Pyrrole-Containing Axially Chiral Skeletons

(2019) Xiao-Long He et al.   ACS Catalysis

Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls

(2019) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

(2018) Yong-Bin Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Regio- and Stereodivergent Access to 1,2-Amino Alcohols or 1,4-Fluoro Alcohols by NHC-Catalyzed Ring Opening of Epoxy enals

(2018) Si Bei Poh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric [2+3] Cyclizations of Azlactones with Azonaphthalenes

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition: Synthesis of Axially Chiral Heterobiaryls

(2018) Yidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scalable, Stereocontrolled Formal Syntheses of (+)-Isoschizandrin and (+)-Steganone: Development and Applications of Palladium(II)-Catalyzed Atroposelective C−H Alkynylation

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Resolution of Heterobiaryl Ketones by Zinc-Catalyzed Asymmetric Hydrosilylation

(2018) Valentín Hornillos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bird's Eye View of Atropisomers Featuring a Five-Membered Ring

(2018) Damien Bonne et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes

(2018) Shiqi Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Vinylogous Amination of 5-Alkyl-4-nitroisoxazoles with a Dipeptide-Based Guanidinium Phase-Transfer Catalyst

(2018) Bo Zhu et al.   ORGANIC LETTERS

Enantioselective Synthesis of Biaryl Atropisomers via Pd/Norbornene-Catalyzed Three-Component Cross-Couplings

(2018) Linlin Ding et al.   ACS Catalysis

Enhanced Reactivity by Torsional Strain of Cyclic Diaryliodonium in Cu-Catalyzed Enantioselective Ring-Opening Reaction

(2018) Kun Zhao et al.   Chem

Access to P - and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cpx IrIII -Catalyzed C−H Arylations

(2018) Yun-Suk Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of Naphthylindole-Derived Phosphines as Organocatalysts in [4 + 1] Cyclizations of o-Quinone Methides with Morita–Baylis–Hillman Carbonates

(2018) Fei Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality

(2018) José A. Carmona et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles

(2018) Sheng-Cai Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Atroposelective C−H Allylation through β-O Elimination: Diverse Synthesis of Axially Chiral Biaryls

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Enantioselective Addition of Chiral Metal Enolates to In Situ Generated ortho -Quinone Methides

(2018) Fabian Göricke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Catalytic Asymmetric Construction of Axially Chiral 3,3′-Bisindole Skeletons

(2018) Chun Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis

(2018) Yu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

(2017) Vivek S. Raut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Atroposelective Synthesis of Arylpyrroles by Catalytic Asymmetric Paal–Knorr Reaction

(2017) Lei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic asymmetric arylation of indoles enabled by azo groups

(2017) Liang-Wen Qi et al.   Nature Chemistry

Organocatalytic synthesis of axially chiral atropisomers

(2017) P. Renzi   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Asymmetric Decarboxylative Amination of β-Keto Acids: Access to Optically Active α-Amino Ketones and 1,2-Amino Alcohols

(2017) Yi Wei et al.   ORGANIC LETTERS

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

(2017) Yong-Bin Wang et al.   Nature Communications

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts

(2016) Samantha Staniland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent Atroposelective Synthesis of Chiral Biaryls by Asymmetric Transfer Hydrogenation: Chiral Phosphoric Acid Catalyzed Dynamic Kinetic Resolution

(2016) Keiji Mori et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons

(2016) Hong-Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Rhodium/Phosphoric Acid Catalysis for the Enantioselective Addition of Oxonium Ylides to ortho -Quinone Methides

(2016) Santosh Kumar Alamsetti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequential Au(i)/chiral tertiary amine catalysis: a tandem C–H functionalization of anisoles or a thiophene/asymmetric Michael addition sequence to quaternary oxindoles

(2016) Zhong-Yan Cao et al.   CHEMICAL COMMUNICATIONS

Synthesis of axially chiral biaryl compounds by asymmetric catalytic reactions with transition metals

(2016) Pauline Loxq et al.   COORDINATION CHEMISTRY REVIEWS

Dynamic Kinetic Resolution of Biaryl Lactones via a Chiral Bifunctional Amine Thiourea-Catalyzed Highly Atropo-enantioselective Transesterification

(2016) Chenguang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Symmetry in Cascade Chirality-Transfer Processes: A Catalytic Atroposelective Direct Arylation Approach to BINOL Derivatives

(2016) Jin-Zheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

3-Naphthylindoles as new promising candidate antioxidant, antibacterial, and antibiofilm agents

(2016) Kavita Sharma et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

(2016) Ji-Wei Zhang et al.   Nature Communications

Direct Asymmetric Dearomatization of 2-Naphthols by Scandium-Catalyzed Electrophilic Amination

(2015) Jiang Nan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combining Organocatalysis with Central-to-Axial Chirality Conversion: Atroposelective Hantzsch-Type Synthesis of 4-Arylpyridines

(2015) Ophélie Quinonero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Stereoselective Synthesis of Imine-Containing Dibenzo[b,d]azepines by a Palladium(II)-Catalyzed [5+2] Oxidative Annulation ofo-Arylanilines with Alkynes

(2015) Zhijun Zuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Practical Organocatalytic Synthesis of Functionalized Non-C 2 -Symmetrical Atropisomeric Biaryls

(2015) Hongyin Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Atropisomeric Vinyl Arene Compounds by Palladium Catalysis: A Carbene Strategy

(2015) Jia Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalyzed Cycloadditions with Unactivated Alkenes by Exclusive Activation of the Electrophile

(2015) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generatedortho-Quinone Methides with 3-Methyl-2-Vinylindoles

(2015) Jia-Jia Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Organocatalytic Asymmetric Prins Cyclization

(2015) Gavin Chit Tsui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonbiaryl and Heterobiaryl Atropisomers: Molecular Templates with Promise for Atropselective Chemical Transformations

(2015) Elango Kumarasamy et al.   CHEMICAL REVIEWS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

ChiralN,N′-Dioxide-Scandium(III)-Catalyzed Asymmetric Dearomatization of 2-Naphthols through an Amination Reaction

(2015) Xiangjin Lian et al.   CHEMISTRY-A EUROPEAN JOURNAL

Simultaneous Induction of Axial and Planar Chirality in Arene-Chromium Complexes by Molybdenum-Catalyzed Enantioselective Ring-Closing Metathesis

(2015) Ken Kamikawa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.

(2015) John G. Luz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2-Naphthols

(2015) Ye-Hui Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Cycloaddition Reactions Catalyzed by BINOL-Derived Phosphoric Acids and N-Triflyl Phosphoramides: Recent Advances

(2015) Felix Held et al.   MOLECULES

Organocatalytic Strategies for the Synthesis of Axially Chiral Compounds

(2015) Giorgio Bencivenni   SYNLETT

Recent Advances in Chiral Phosphoric Acid Catalyzed Asymmetric Reactions for the Synthesis of Enantiopure Indole Derivatives

(2015) Hua Wu et al.   SYNTHESIS-STUTTGART

Enantio- and Diastereoselective Access to Distant Stereocenters Embedded within Tetrahydroxanthenes: Utilizingortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalysis

(2014) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Synthesis of Atropisomeric Biaryls: A Cation-Directed Nucleophilic Aromatic Substitution Reaction

(2014) Roly J. Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid

(2014) Dao-Juan Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation

(2014) Achim Link et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Arylative Dearomatization of 2,3-Disubstituted Indoles Enabled by Tandem Reactions

(2014) Yu-Chen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Catalyzed, Conjugate Addition of β-Dicarbonyls to In Situ Generatedortho-Quinone Methides-Enantioselective Synthesis of 4-Aryl-4H-Chromenes

(2014) Osama El-Sepelgy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Formation of All-Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

(2014) Wanxiang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric synthesis of heteroaryl atropisomers via a gold-catalyzed cycloisomerization–amination cascade reaction

(2014) Rui Guo et al.   CHEMICAL COMMUNICATIONS

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Recent Advances in Stereoselective [2+2+2] Cycloadditions

(2014) Muriel Amatore et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Remote Control of Axial Chirality: Aminocatalytic Desymmetrization of N-Arylmaleimides via Vinylogous Michael Addition

(2014) Nicola Di Iorio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Intermolecular Direct C–H Bond Iodination: An Efficient Approach toward the Synthesis of Axially Chiral Compounds via Kinetic Resolution

(2014) De-Wei Gao et al.   ACS Catalysis

Conquering three-carbon axial chirality of allenes

(2014) Juntao Ye et al.   Organic Chemistry Frontiers

Catalytic Asymmetric Benzidine Rearrangement

(2013) Chandra Kanta De et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Hibarimicinone, a v-Src Tyrosine Kinase Inhibitor Possessing the Pseudo-Dimer Structure of Tetracycline

(2013) Kuniaki Tatsuta et al.   CHEMICAL RECORD

Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

(2013) Guangqing Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Cross-Coupling Strategy for the Asymmetric Synthesis of Axially Chiral Heterobiaryls

(2013) Abel Ros et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of QUINAP via Dynamic Kinetic Resolution

(2013) Vikram Bhat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Multisubstituted Biaryl Skeleton by Chiral Phosphoric Acid Catalyzed Desymmetrization/Kinetic Resolution Sequence

(2013) Keiji Mori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Aryl–Aryl Bond Formation: An Atroposelective [3,3]-Rearrangement Approach to BINAM Derivatives

(2013) Gong-Qiang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles

(2011) Gopinadhan N. Anilkumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent advances in [2+2+2] cycloaddition reactions

(2011) Gema Domínguez et al.   CHEMICAL SOCIETY REVIEWS

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recent developments on chiral P,S-type ligands and their applications in asymmetric catalysis

(2010) Fuk Loi Lam et al.   CHEMICAL COMMUNICATIONS

Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety

(2010) Anna J. Kochanowska-Karamyan et al.   CHEMICAL REVIEWS

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Catalytic Enantioselective Synthesis of Atropisomeric Indoles with an NC Chiral Axis

(2010) Nobutaka Ototake et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of Biphenols from 1,4-Diketones by Traceless Central-to-Axial Chirality Exchange

(2010) Fenghai Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Resolution of Biaryl Atropisomers via Peptide-Catalyzed Asymmetric Bromination

(2010) J. L. Gustafson et al.   SCIENCE

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Catalytic Functionalization of Indoles in a New Dimension

(2009) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed Enantioselective [2+2+2] Cycloadditions for the Synthesis of Axially Chiral Biaryls

(2008) Ken Tanaka   Chemistry-An Asian Journal

Knipholone and related 4-phenylanthraquinones: structurally, pharmacologically, and biosynthetically remarkable natural products

(2008) Gerhard Bringmann et al.   NATURAL PRODUCT REPORTS