Combining Organocatalysis with Central-to-Axial Chirality Conversion: Atroposelective Hantzsch-Type Synthesis of 4-Arylpyridines

Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor

(2015) Keith R. Fandrick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic multicomponent synthesis of enantioenriched polycyclic 1,2,3,4-tetrahydropyridines: key substrate selection enabling regio- and stereoselectivities

(2015) Yohan Dudognon et al.   CHEMICAL COMMUNICATIONS

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

(2015) J. Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Organocatalyzed Asymmetric Synthesis of Axially, Planar, and Helical Chiral Compounds

(2015) Seiji Shirakawa et al.   Chemistry-An Asian Journal

Bifunctional Organocatalysts for the Enantioselective Synthesis of Axially Chiral Isoquinoline N-Oxides

(2015) Ryota Miyaji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Organocatalytic Strategies for the Synthesis of Axially Chiral Compounds

(2015) Giorgio Bencivenni   SYNLETT

N-Heterocyclic carbene catalysed redox isomerisation of esters to functionalised benzaldehydes

(2015) Lisa Candish et al.   Chemical Science

In-depth structure–selectivity investigations on asymmetric, copper-catalyzed oxidative biaryl coupling in the presence of 5-cis-substituted prolinamines

(2015) Felix Prause et al.   Catalysis Science & Technology

Organocatalytic Enantioselective Multicomponent Synthesis of Pyrrolopiperazines

(2014) Haiying Du et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Enantioselective Construction of Polyaromatic Architectures

(2014) Ophélie Quinonero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluxionally Chiral DMAP Catalysts: Kinetic Resolution of Axially Chiral Biaryl Compounds

(2014) Gaoyuan Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Synthesis of Atropisomeric Biaryls: A Cation-Directed Nucleophilic Aromatic Substitution Reaction

(2014) Roly J. Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid

(2014) Dao-Juan Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation

(2014) Achim Link et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective Acylation

(2014) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselectively-Catalyzed Reactions with (E)-2-Alkenoyl-pyridines, Their N-Oxides, and the Corresponding Chalcones

(2014) Giovanni Desimoni et al.   CHEMICAL REVIEWS

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Metal-Free Multicomponent Syntheses of Pyridines

(2014) Christophe Allais et al.   CHEMICAL REVIEWS

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Organocatalytic Multicomponent Synthesis of 2,6-Diazabicyclo[2.2.2]octanones

(2013) Maria del Mar Sanchez Duque et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of Axially Chiral 2-Amino-1,1′-Biaryls by Phase-Transfer-Catalyzed N-Allylation

(2013) Seiji Shirakawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Benzidine Rearrangement

(2013) Chandra Kanta De et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biological Stereoselectivity of Atropisomeric Natural Products and Drugs

(2013) Arie Zask et al.   CHIRALITY

Michael Addition-initiated Sequential Reactions from 1,3-dicarbonyls for the Synthesis of Polycyclic Heterocycles

(2013) Xavier Bugaut et al.   CURRENT ORGANIC CHEMISTRY

Total Synthesis of the Antitumor Antibiotic (±)-Streptonigrin: First- and Second-Generation Routes for de Novo Pyridine Formation Using Ring-Closing Metathesis

(2013) Timothy J. Donohoe et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of Multisubstituted Biaryl Skeleton by Chiral Phosphoric Acid Catalyzed Desymmetrization/Kinetic Resolution Sequence

(2013) Keiji Mori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Aryl–Aryl Bond Formation: An Atroposelective [3,3]-Rearrangement Approach to BINAM Derivatives

(2013) Gong-Qiang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Organocatalyzed Domino Synthesis of Six-Membered Carbocycles

(2013) Damien Bonne et al.   SYNTHESIS-STUTTGART

Bifunctional chiral urea catalyzed highly enantioselective Michael addition of cyclic 1,3-dicarbonyl compounds to 2-enoylpyridines

(2013) Nagaraju Molleti et al.   TETRAHEDRON LETTERS

Prediction of suitable catalyst by 1H NMR: asymmetric synthesis of multisubstituted biaryls by chiral phosphoric acid catalyzed asymmetric bromination

(2013) Keiji Mori et al.   Chemical Science

Synthesis of unsymmetrically substituted 2,2′-dihydroxy-1,1′-biaryl derivatives using organic-base-catalyzed Ferrier-type rearrangement as the key step

(2012) Masahiro Terada et al.   CHEMICAL COMMUNICATIONS

New Approaches to Nitrogen Containing Heterocycles: Enantioselective Organocatalyzed Synthesis of Dihydropyridines (DHP's), Quinolizidine Derivatives and Dihydropyrimidines (DHPM's)

(2012) Hoai Thu Pham et al.   CURRENT ORGANIC CHEMISTRY

Synthesis of Atropisomerically Defined, Highly Substituted Biaryl Scaffolds through Catalytic Enantioselective Bromination and Regioselective Cross-Coupling

(2011) Jeffrey L. Gustafson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Enantioselective Intramolecular Hydroarylation of Alkynes To Form Axially Chiral 4-Aryl 2-Quinolinones

(2011) Tetsuro Shibuya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Total Synthesis and Studies into the Configurational Stability of Bismurrayaquinone A

(2011) Leah C. Konkol et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of Biphenols from 1,4-Diketones by Traceless Central-to-Axial Chirality Exchange

(2010) Fenghai Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Resolution of Biaryl Atropisomers via Peptide-Catalyzed Asymmetric Bromination

(2010) J. L. Gustafson et al.   SCIENCE

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

(2009) Marisa C. Kozlowski et al.   CHEMICAL SOCIETY REVIEWS

BValues as a Sensitive Measure of Steric Effects

(2009) Renzo Ruzziconi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Three-Component Cyclization of Cinnamaldehydes and Primary Amines with 1,3-Dicarbonyl Compounds: Straightforward Access to Enantiomerically Enriched Dihydropyridines

(2008) Jun Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-free Michael addition initiated multicomponent oxidative cyclodehydration route to polysubstituted pyridines from 1,3-dicarbonyls

(2008) Frédéric Liéby-Muller et al.   CHEMICAL COMMUNICATIONS

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE

Organocatalytic Enantioselective One-Pot Synthesis and Application of Substituted 1,4-Dihydropyridines-Hantzsch Ester Analogues

(2007) Patrick T. Franke et al.   Chemistry-An Asian Journal

Atropisomerism in the 2-Arylimino-N-(2-hydroxyphenyl)thiazoline Series:  Influence of Hydrogen Bonding on the Racemization Process

(2007) Christian Roussel et al.   JOURNAL OF ORGANIC CHEMISTRY