Aspects of Gut Microbiota and Immune System Interactions in Infectious Diseases, Immunopathology, and Cancer

The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy

(2018) Vancheswaran Gopalakrishnan et al.   CANCER CELL

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells

(2018) Liam Chung et al.   Cell Host & Microbe

Gut Dysbiosis Associated With Hepatitis C Virus Infection

(2018) Takako Inoue et al.   CLINICAL INFECTIOUS DISEASES

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Environment dominates over host genetics in shaping human gut microbiota

(2018) Daphna Rothschild et al.   NATURE

Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice

(2017) Ho Tsoi et al.   GASTROENTEROLOGY

Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota

(2017) Rui M Ferreira et al.   GUT

The Gut Microbiota and Alzheimer’s Disease

(2017) Chunmei Jiang et al.   JOURNAL OF ALZHEIMERS DISEASE

Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation

(2017) Jonathan U. Peled et al.   JOURNAL OF CLINICAL ONCOLOGY

Influence of the Gut Microbiome on Autoimmunity in the Central Nervous System

(2017) Sara L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

Influence of diet on the gut microbiome and implications for human health

(2017) Rasnik K. Singh et al.   Journal of Translational Medicine

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Probiotic engineering: towards development of robust probiotic strains with enhanced functional properties and for targeted control of enteric pathogens

(2017) Moloko Gloria Mathipa et al.   Gut Pathogens

Variations in oral microbiota associated with oral cancer

(2017) Hongsen Zhao et al.   Scientific Reports

Detrimental Impact of Microbiota-Accessible Carbohydrate-Deprived Diet on Gut and Immune Homeostasis: An Overview

(2017) Claire Immediato Daïen et al.   Frontiers in Immunology

Porphyromonas gingivalis disturbs host–commensal homeostasis by changing complement function

(2017) Ingar Olsen et al.   Journal of Oral Microbiology

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

(2017) Arthur E. Frankel et al.   NEOPLASIA

The Intestinal Microbiome in Infectious Diseases: The Clinical Relevance of a Rapidly Emerging Field

(2017) Vanessa C Harris et al.   Open Forum Infectious Diseases

Hyperinduction of Wnt Activity: A New Paradigm for the Treatment of Colorectal Cancer?

(2017) Michael Bordonaro et al.   ONCOLOGY RESEARCH

Association between intestinal permeability and faecal microbiota composition in Italian children with beta cell autoimmunity at risk for type 1 diabetes

(2016) Claudio Maffeis et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The Role of Antibiotics in Gut Microbiota Modulation: The Eubiotic Effects of Rifaximin

(2016) Francesca Romana Ponziani et al.   DIGESTIVE DISEASES

Antibiotics as deep modulators of gut microbiota: between good and evil

(2016) Gianluca Ianiro et al.   GUT

Changing epidemiology of oral squamous cell carcinoma of the tongue: A global study

(2016) Jia Hui Ng et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The microbiome and innate immunity

(2016) Christoph A. Thaiss et al.   NATURE

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

When pathogenic bacteria meet the intestinal microbiota

(2016) Nathalie Rolhion et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Effect ofPropionibacterium freudenreichiionSalmonellamultiplication, motility, and association with avian epithelial cells

(2016) Divek V. T. Nair et al.   POULTRY SCIENCE

Antibiotic use and its consequences for the normal microbiome

(2016) Martin J. Blaser   SCIENCE

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice

(2016) Yusuke Shono et al.   Science Translational Medicine

Dairy propionibacteria as probiotics: recent evidences

(2016) Clelia Altieri   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

(2016) Krista Dubin et al.   Nature Communications

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

(2016) Katri Korpela et al.   Nature Communications

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

(2016) Rafael Guerrero-Preston et al.   Oncotarget

Developmental dynamics of the preterm infant gut microbiota and antibiotic resistome

(2016) Molly K. Gibson et al.   Nature Microbiology

Effects of Arabinoxylan and Resistant Starch on Intestinal Microbiota and Short-Chain Fatty Acids in Subjects with Metabolic Syndrome: A Randomised Crossover Study

(2016) Stine Hald et al.   PLoS One

Role of the Gut Microbiome in Modulating Arthritis Progression in Mice

(2016) Xiaofei Liu et al.   Scientific Reports

Screening of Propionibacterium spp. for potential probiotic properties

(2015) Daniela Campaniello et al.   ANAEROBE

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease

(2015) Robert R. Jenq et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Mammalian Lipopolysaccharide Receptors Incorporated into the Retroviral Envelope Augment Virus Transmission

(2015) Jessica Wilks et al.   Cell Host & Microbe

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Determining the Long-term Effect of Antibiotic Administration on the Human Normal Intestinal Microbiota Using Culture and Pyrosequencing Methods

(2015) Mamun-Ur Rashid et al.   CLINICAL INFECTIOUS DISEASES

Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes

(2015) Aimon K. Alkanani et al.   DIABETES

Th17 Cells as Potential Probiotic Therapeutic Targets in Inflammatory Bowel Diseases

(2015) Eddy Owaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metagenomic analysis of the impact of nitrofurantoin treatment on the human faecal microbiota

(2015) J. Vervoort et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A comprehensive repertoire of prokaryotic species identified in human beings

(2015) Perrine Hugon et al.   LANCET INFECTIOUS DISEASES

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

High frequencies of antibiotic resistance genes in infants’ meconium and early fecal samples

(2015) M. J. Gosalbes et al.   Journal of Developmental Origins of Health and Disease

Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples

(2015) Nezar Noor Al-Hebshi et al.   Journal of Oral Microbiology

Dynamics of Gut Microbiota in Autoimmune Lupus

(2014) Husen Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans

(2014) Fabio Pibiri et al.   CANCER CAUSES & CONTROL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection

(2014) Arya Khosravi et al.   Cell Host & Microbe

Compromised Gut Microbiota Networks in Children With Anti-Islet Cell Autoimmunity

(2014) David Endesfelder et al.   DIABETES

The role of commensal bacteria in the regulation of sensitization to food allergens

(2014) Severine Cao et al.   FEBS LETTERS

Antibiotics and the gut microbiota

(2014) Sheetal R. Modi et al.   JOURNAL OF CLINICAL INVESTIGATION

Pseudomonas aeruginosa Quorum-Sensing Molecule Homoserine Lactone Modulates Inflammatory Signaling through PERK and eI-F2 

(2014) M. A. Grabiner et al.   JOURNAL OF IMMUNOLOGY

Commensal Gram-positive bacteria initiates colitis by inducing monocyte/macrophage mobilization

(2014) Y Nakanishi et al.   Mucosal Immunology

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Meconium Microbiome Analysis Identifies Bacteria Correlated with Premature Birth

(2014) Alexandria N. Ardissone et al.   PLoS One

Effects of β-Lactam Antibiotics and Fluoroquinolones on Human Gut Microbiota in Relation to Clostridium difficile Associated Diarrhea

(2014) Henrik Knecht et al.   PLoS One

Changes in Abundance of Oral Microbiota Associated with Oral Cancer

(2014) Brian L. Schmidt et al.   PLoS One

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Modulation of immune development and function by intestinal microbiota

(2014) Agnieszka M. Kabat et al.   TRENDS IN IMMUNOLOGY

Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

(2014) A. Hevia et al.   mBio

Diet-Induced Alterations in Gut Microflora Contribute to Lethal Pulmonary Damage in TLR2/TLR4-Deficient Mice

(2014) Yewei Ji et al.   Cell Reports

Shifting the paradigm from pathogens to pathobiome: new concepts in the light of meta-omics

(2014) Muriel Vayssier-Taussat et al.   Frontiers in Cellular and Infection Microbiology

Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease

(2014) Jose U. Scher et al.   Arthritis & Rheumatology

Inflammatory Bowel Disease: Mechanisms, Redox Considerations, and Therapeutic Targets

(2013) Fiorella Biasi et al.   ANTIOXIDANTS & REDOX SIGNALING

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Bacteriotherapy for the treatment of intestinal dysbiosis caused by Clostridium difficile infection

(2013) Blessing O Adamu et al.   CURRENT OPINION IN MICROBIOLOGY

Pseudomonas aeruginosa -Eukaryotic Cell Crosstalk: Mediators, Mechanisms and Implications for the Antimicrobial Therapy

(2013) Carmen Curutiu et al.   CURRENT ORGANIC CHEMISTRY

Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis

(2013) Grace Y. Chen   EUROPEAN JOURNAL OF IMMUNOLOGY

The Th17 Cell Population and the Immune Homeostasis of the Gastrointestinal Tract

(2013) Mauro Rossi et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Substrate Cleavage Profiling Suggests a Distinct Function ofBacteroides fragilisMetalloproteinases (Fragilysin and Metalloproteinase II) at the Microbiome-Inflammation-Cancer Interface

(2013) Sergey A. Shiryaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic Protection of Combined Probiotic Conditioned Media against Neonatal Necrotizing Enterocolitis-Like Intestinal Injury

(2013) Sheng-Ru Shiou et al.   PLoS One

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

(2013) B. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

The Hygiene Hypothesis: An Explanation for the Increased Frequency of Insulin-Dependent Diabetes

(2013) J.-F. Bach et al.   Cold Spring Harbor Perspectives in Medicine

Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control

(2013) S. T. Rutherford et al.   Cold Spring Harbor Perspectives in Medicine

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma

(2012) Smruti Pushalkar et al.   BMC MICROBIOLOGY

Effects of probiotic Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS supplementation on intestinal and systemic markers of inflammation in ApoE*3Leiden mice consuming a high-fat diet

(2012) Anna Oksaharju et al.   BRITISH JOURNAL OF NUTRITION

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice

(2012) Frederic A. Carvalho et al.   Cell Host & Microbe

Microbial culturomics: paradigm shift in the human gut microbiome study

(2012) J.-C. Lagier et al.   CLINICAL MICROBIOLOGY AND INFECTION

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

(2012) Jean Guy LeBlanc et al.   CURRENT OPINION IN BIOTECHNOLOGY

Fecal Microbiota Composition Differs Between Children With  -Cell Autoimmunity and Those Without

(2012) M. C. de Goffau et al.   DIABETES

Is the origin of type 1 diabetes in the gut?

(2012) Outi Vaarala   IMMUNOLOGY AND CELL BIOLOGY

The gut anaerobe Faecalibacterium prausnitzii uses an extracellular electron shuttle to grow at oxic–anoxic interphases

(2012) M Tanweer Khan et al.   ISME Journal

Olive Leaf Extract as a Hypoglycemic Agent in Both Human Diabetic Subjects and in Rats

(2012) Julio Wainstein et al.   JOURNAL OF MEDICINAL FOOD

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

The Human Gut Microbiota and Undernutrition

(2012) J. I. Gordon et al.   Science Translational Medicine

Effect of Breast and Formula Feeding on Gut Microbiota Shaping in Newborns

(2012) Federica Guaraldi et al.   Frontiers in Cellular and Infection Microbiology

Quorum sensing in biofilms – How to destroy the bacterial citadels or their cohesion/power?

(2011) Veronica Lazar   ANAEROBE

The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin

(2011) Casey T. Weaver et al.   Annual Review of Pathology-Mechanisms of Disease

Dietary Fiber Intake and Mortality in the NIH-AARP Diet and Health Study

(2011) Yikyung Park et al.   ARCHIVES OF INTERNAL MEDICINE

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Bacteroides in the Infant Gut Consume Milk Oligosaccharides via Mucus-Utilization Pathways

(2011) Angela Marcobal et al.   Cell Host & Microbe

Retinoic Acid Attenuates Ileitis by Restoring the Balance Between T-Helper 17 and T Regulatory Cells

(2011) Colm B. Collins et al.   GASTROENTEROLOGY

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

(2011) Premysl Bercik et al.   GASTROENTEROLOGY

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

Understanding type 1 diabetes through genetics: advances and prospects

(2011) Constantin Polychronakos et al.   NATURE REVIEWS GENETICS

Gut Microbiome Metagenomics Analysis Suggests a Functional Model for the Development of Autoimmunity for Type 1 Diabetes

(2011) Christopher T. Brown et al.   PLoS One

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Presence of Porphyromonas gingivalis in gingival squamous cell carcinoma

(2011) Joseph Katz et al.   International Journal of Oral Science

Gut Microbiota, Immunity, and Disease: A Complex Relationship

(2011) Michele M. Kosiewicz et al.   Frontiers in Microbiology

Salmonella Interaction with and Passage through the Intestinal Mucosa: Through the Lens of the Organism

(2011) Kelly Hallstrom et al.   Frontiers in Microbiology

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

Gut, bugs, and brain: Role of commensal bacteria in the control of central nervous system disease

(2010) Javier Ochoa-Repáraz et al.   ANNALS OF NEUROLOGY

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Microbial diversity in saliva of oral squamous cell carcinoma

(2010) Smruti Pushalkar et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Structural shifts of gut microbiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure

(2010) Hua Wei et al.   FEMS MICROBIOLOGY ECOLOGY

Pseudomonas aeruginosaHomoserine Lactone Activates Store-operated cAMP and Cystic Fibrosis Transmembrane Regulator-dependent Cl−Secretion by Human Airway Epithelia

(2010) Christian Schwarzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative Metagenomic Study of Alterations to the Intestinal Microbiota and Risk of NosocomialClostridum difficile–Associated Disease

(2010) Amee R. Manges et al.   JOURNAL OF INFECTIOUS DISEASES

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Short-Term Antibiotic Treatment Has Differing Long-Term Impacts on the Human Throat and Gut Microbiome

(2010) Hedvig E. Jakobsson et al.   PLoS One

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bifidobacterium bifidum improves intestinal integrity in a rat model of necrotizing enterocolitis

(2009) Ludmila Khailova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Helicobacter Pylori associated global gastric cancer burden

(2009) Sam et al.   Frontiers in Bioscience-Landmark

The impact of dietary and lifestyle risk factors on risk of colorectal cancer: A quantitative overview of the epidemiological evidence

(2009) Rachel R. Huxley et al.   INTERNATIONAL JOURNAL OF CANCER

AI-2 signalling is induced by acidic shock in probiotic strains of Lactobacillus spp.

(2009) Saloomeh Moslehi-Jenabian et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Molecular characterization of the stomach microbiota in patients with gastric cancer and in controls

(2009) J. Dicksved et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Quorum sensing and social networking in the microbial world

(2009) S. Atkinson et al.   Journal of the Royal Society Interface

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Probiotics and gastrointestinal disease: successes, problems and future prospects

(2009) Eamonn P Culligan et al.   Gut Pathogens

Bacterial Quorum Sensing: Signals, Circuits, and Implications for Biofilms and Disease

(2008) Arul Jayaraman et al.   Annual Review of Biomedical Engineering

Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin

(2008) Kai Truusalu et al.   BMC MICROBIOLOGY

Effects of Multispecies Probiotic Combination on Helicobacter pylori Infection In Vitro

(2008) E. Myllyluoma et al.   Clinical and Vaccine Immunology

The "Perfect Storm" for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity

(2008) O. Vaarala et al.   DIABETES

Microbes in Gastrointestinal Health and Disease

(2008) Andrew S. Neish   GASTROENTEROLOGY

Colonization dynamics of ampicillin-resistant Escherichia coli in the infantile colonic microbiota

(2008) N. Karami et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Inter-kingdom signalling: communication between bacteria and their hosts

(2008) David T. Hughes et al.   NATURE REVIEWS MICROBIOLOGY