标题
Fibrosis—a lethal component of systemic sclerosis
作者
关键词
-
出版物
Nature Reviews Rheumatology
Volume 10, Issue 7, Pages 390-402
出版商
Springer Nature
发表日期
2014-04-22
DOI
10.1038/nrrheum.2014.53
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome
- (2014) Wen-Xing Ding et al. Autophagy
- Mortality in systemic sclerosis
- (2014) Mandana Nikpour et al. CURRENT OPINION IN RHEUMATOLOGY
- Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation
- (2014) Ceri A. Fielding et al. IMMUNITY
- A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses
- (2013) Jun Wei et al. ANNALS OF THE RHEUMATIC DISEASES
- Increased Expression of Endoplasmic Reticulum Stress and Unfolded Protein Response Genes in Peripheral Blood Mononuclear Cells From Patients With Limited Cutaneous Systemic Sclerosis and Pulmonary Arterial Hypertension
- (2013) Stefania Lenna et al. ARTHRITIS AND RHEUMATISM
- Targeting Interleukin-6 in Rheumatoid Arthritis
- (2013) Md Yuzaiful Md Yusof et al. DRUGS
- LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation
- (2013) Norihiko Sakai et al. FASEB JOURNAL
- Evidence for progressive reduction and loss of telocytes in the dermal cellular network of systemic sclerosis
- (2013) Mirko Manetti et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
- (2013) Yong Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma
- (2013) K. Makino et al. JOURNAL OF IMMUNOLOGY
- Race and Association With Disease Manifestations and Mortality in Scleroderma
- (2013) Allan C. Gelber et al. MEDICINE
- Targeted therapies for systemic sclerosis
- (2013) Christopher P. Denton et al. Nature Reviews Rheumatology
- Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing
- (2013) L. S. Velasquez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-150 Down-Regulation Contributes to the Constitutive Type I Collagen Overexpression in Scleroderma Dermal Fibroblasts via the Induction of Integrin β3
- (2012) Noritoshi Honda et al. AMERICAN JOURNAL OF PATHOLOGY
- Outcomes of patients with systemic sclerosis-associated polyarthritis and myopathy treated with tocilizumab or abatacept: a EUSTAR observational study
- (2012) Muriel Elhai et al. ANNALS OF THE RHEUMATIC DISEASES
- The Unfolded Protein Response in Secretory Cell Function
- (2012) Kristin A. Moore et al. Annual Review of Genetics
- Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells
- (2012) Jun Wei et al. ARTHRITIS AND RHEUMATISM
- Lysoglycerophospholipids in chronic inflammatory disorders: The PLA2/LPC and ATX/LPA axes
- (2012) Ioanna Sevastou et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Endoplasmic reticulum stress as a pro-fibrotic stimulus
- (2012) Harikrishna Tanjore et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
- (2012) Fa-Xing Yu et al. CELL
- Lipids and eicosanoids in fibrosis
- (2012) Flavia V. Castelino CURRENT OPINION IN RHEUMATOLOGY
- The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis
- (2012) Stefania Lenna et al. CURRENT OPINION IN RHEUMATOLOGY
- Biomechanical regulation of mesenchymal cell function
- (2012) Daniel J. Tschumperlin et al. CURRENT OPINION IN RHEUMATOLOGY
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Elevated Serum Levels of Arachidonoyl-lysophosphatidic Acid and Sphingosine 1-Phosphate in Systemic Sclerosis
- (2012) Akira Tokumura et al. International Journal of Medical Sciences
- Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
- (2012) Chunguo Jiang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Telocytes in human skin - are they involved in skin regeneration?
- (2012) Laura Ceafalan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
- (2012) Ioanna Nikitopoulou et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Heat shock protein 90 inhibitor attenuates renal fibrosis through degradation of transforming growth factor-β type II receptor
- (2012) Hyunjin Noh et al. LABORATORY INVESTIGATION
- Inhibition of Notch Signaling by a γ-Secretase Inhibitor Attenuates Hepatic Fibrosis in Rats
- (2012) Yixiong Chen et al. PLoS One
- Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts
- (2012) X. Shi-wen et al. RHEUMATOLOGY
- The Hsp90 inhibitor 17-AAG represses calcium-induced cytokeratin 1 and 10 expression in HaCaT keratinocytes
- (2012) Sadanori Miyoshi et al. FEBS Open Bio
- Dendritic cells a double-edge sword in autoimmune responses
- (2012) Giada Amodio et al. Frontiers in Immunology
- Relaxin Regulates Myofibroblast Contractility and Protects against Lung Fibrosis
- (2011) Xiangwei Huang et al. AMERICAN JOURNAL OF PATHOLOGY
- Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis
- (2011) C. Dees et al. ANNALS OF THE RHEUMATIC DISEASES
- Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis
- (2011) Clara Dees et al. ARTHRITIS AND RHEUMATISM
- Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?
- (2011) Jun Wei et al. ARTHRITIS AND RHEUMATISM
- Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma
- (2011) Flavia V. Castelino et al. ARTHRITIS AND RHEUMATISM
- Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation
- (2011) David Lagares et al. ARTHRITIS AND RHEUMATISM
- Insights into the pharmacological relevance of lysophospholipid receptors
- (2011) Tetsuji Mutoh et al. BRITISH JOURNAL OF PHARMACOLOGY
- Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy
- (2011) Laurentiu M. Popescu et al. CELL AND TISSUE RESEARCH
- Scleroderma-like properties of skin from caveolin-1-deficient mice
- (2011) Remedios Castello-Cros et al. CELL CYCLE
- An update on an immune system that goes awry in systemic sclerosis
- (2011) L. van Bon et al. CURRENT OPINION IN RHEUMATOLOGY
- Role of IL-13 in systemic sclerosis
- (2011) Patrizia Fuschiotti CYTOKINE
- TGF-β signaling in fibrosis
- (2011) Anna Biernacka et al. GROWTH FACTORS
- Myocardin-related Transcription Factor-A Complexes Activate Type I Collagen Expression in Lung Fibroblasts
- (2011) Larry L. Luchsinger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dendritic Cells and Damage-Associated Molecular Patterns: Endogenous Danger Signals Linking Innate and Adaptive Immunity
- (2011) Gary Nace et al. Journal of Innate Immunity
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling
- (2011) Victor W Wong et al. NATURE MEDICINE
- Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
- (2011) Swati Bhattacharyya et al. Nature Reviews Rheumatology
- Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis
- (2011) N. Washida et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
- (2011) J. R. Rock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Angiogenesis and Vasculopathy in Systemic Sclerosis: Evolving Concepts
- (2011) Bradley J. Rabquer et al. Current Rheumatology Reports
- Dendritic Cells: Novel Players in Fibrosis and Scleroderma
- (2011) Theresa T. Lu Current Rheumatology Reports
- An Essential Role for Resident Fibroblasts in Experimental Lung Fibrosis Is Defined by Lineage-Specific Deletion of High-Affinity Type II Transforming Growth Factor β Receptor
- (2010) Rachel K. Hoyles et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- MicroRNA-29, a key regulator of collagen expression in systemic sclerosis
- (2010) Britta Maurer et al. ARTHRITIS AND RHEUMATISM
- Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction
- (2010) Eric M. Small et al. CIRCULATION RESEARCH
- Diagnosis and Classification of Systemic Sclerosis
- (2010) Eric Hachulla et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer
- (2010) Alexander Schultze et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
- (2010) Fei Liu et al. JOURNAL OF CELL BIOLOGY
- Telocytes as supporting cells for myocardial tissue organization in developing and adult heart
- (2010) Daniele Bani et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Poly(I:C) Drives Type I IFN- and TGFβ-Mediated Inflammation and Dermal Fibrosis Simulating Altered Gene Expression in Systemic Sclerosis
- (2010) Giuseppina A. Farina et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
- (2010) Curtis A Thorne et al. Nature Chemical Biology
- Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment
- (2010) Vivian Barry-Hamilton et al. NATURE MEDICINE
- Cellular and molecular aspects of vascular dysfunction in systemic sclerosis
- (2010) Maria Trojanowska Nature Reviews Rheumatology
- PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis
- (2010) Jun Wei et al. PLoS One
- The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
- (2010) Y. Shima et al. RHEUMATOLOGY
- Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γ
- (2009) Minghua Wu et al. AMERICAN JOURNAL OF PATHOLOGY
- Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
- (2009) Benjamin D. Humphreys et al. AMERICAN JOURNAL OF PATHOLOGY
- Effector CD8+ T cells in systemic sclerosis patients produce abnormally high levels of interleukin-13 associated with increased skin fibrosis
- (2009) Patrizia Fuschiotti et al. ARTHRITIS AND RHEUMATISM
- Loss of peroxisome proliferator-activated receptor γ in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis
- (2009) Mohit Kapoor et al. ARTHRITIS AND RHEUMATISM
- Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress
- (2009) Yoshihito Ishida et al. Autophagy
- Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
- (2009) Asish K. Ghosh et al. FASEB JOURNAL
- Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice
- (2009) Kojiro Taura et al. HEPATOLOGY
- Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis
- (2009) Borna Mehrad et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Increased Frequency and Compromised Function of T Regulatory Cells in Systemic Sclerosis (SSc) Is Related to a Diminished CD69 and TGFβ Expression
- (2009) Timothy R. D. J. Radstake et al. PLoS One
- Cutaneous Chronic Graft-Versus-Host Disease Does Not Have the Abnormal Endothelial Phenotype or Vascular Rarefaction Characteristic of Systemic Sclerosis
- (2009) Jo Nadine Fleming et al. PLoS One
- Enhanced interleukin‐10 production by dendritic cells upon stimulation with Toll‐like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretion
- (2009) A. W. T. van Lieshout et al. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
- Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney
- (2008) Shuei-Liong Lin et al. AMERICAN JOURNAL OF PATHOLOGY
- Activation of Toll-Like Receptor 3 Augments Myofibroblast Differentiation
- (2008) Hisatoshi Sugiura et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts
- (2008) Alfiya Akhmetshina et al. ARTHRITIS AND RHEUMATISM
- Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4
- (2008) Serena Fineschi et al. ARTHRITIS AND RHEUMATISM
- Central role of dendritic cells in the regulation and deregulation of immune responses
- (2008) F. Granucci et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation
- (2008) A. Meneghin et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Regulatory Effect of Extracellular Signal-Regulated Kinases (ERK) on Type I Collagen Synthesis in Human Dermal Fibroblasts Stimulated by IL-4 and IL-13
- (2008) Rashpal K. Bhogal et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Surface morphology and mechanical properties of fibroblasts from scleroderma patients
- (2008) Adam Reich et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Thiazolidinediones Downregulate Wnt/β-Catenin Signaling Via Multiple Mechanisms in Breast Cancer Cells
- (2008) Pei-Shan Wang et al. JOURNAL OF SURGICAL RESEARCH
- TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
- (2008) Xaralabos Varelas et al. NATURE CELL BIOLOGY
- Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin
- (2008) Ausra Milano et al. PLoS One
- Critical regulation of TGF signaling by Hsp90
- (2008) K. H. Wrighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search