Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

Endothelin 1 contributes to the effect of transforming growth factor β1 on wound repair and skin fibrosis

(2010) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model

(2010) Cedo M Bagi et al.   CANCER BIOLOGY & THERAPY

Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts

(2010) Guo-qiang Cai et al.   EXPERIMENTAL CELL RESEARCH

Expression of integrin  1 by fibroblasts is required for tissue repair in vivo

(2010) S. Liu et al.   JOURNAL OF CELL SCIENCE

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

FRNK overexpression limits the depth and frequency of vascular smooth muscle cell invasion in a three-dimensional fibrin matrix

(2010) L.P. Brewster et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Focal adhesion kinase mediates TGF-β1-induced renal tubular epithelial-to-mesenchymal transition in vitro

(2010) Bingqing Deng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Loss of β1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model

(2009) Shangxi Liu et al.   ARTHRITIS AND RHEUMATISM

CTGF enhances migration and MMP-13 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells

(2009) Tzu-Wei Tan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

Insulin-Like Growth Factor-II Is Increased in Systemic Sclerosis-Associated Pulmonary Fibrosis and Contributes to the Fibrotic Process via Jun N-Terminal Kinase- and Phosphatidylinositol-3 Kinase-Dependent Pathways

(2008) Eileen Hsu et al.   AMERICAN JOURNAL OF PATHOLOGY

c-Jun N-Terminal Kinase 1 Is Required for the Development of Pulmonary Fibrosis

(2008) John F. Alcorn et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Standardized quantification of pulmonary fibrosis in histological samples

(2008) Ralf-Harto Hübner et al.   BIOTECHNIQUES

Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors

(2008) Cedo M. Bagi et al.   CANCER

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

(2008) W. G. Roberts et al.   CANCER RESEARCH

Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity

(2008) Zeinab Daher et al.   CELLULAR SIGNALLING

Protein Kinase Inhibitors in the Treatment of Pulmonary Fibrosis

(2008) Sylvie Garneau-Tsodikova et al.   CURRENT MEDICINAL CHEMISTRY

Focal Adhesion Kinase (FAK)-related Non-kinase Inhibits Myofibroblast Differentiation through Differential MAPK Activation in a FAK-dependent Manner

(2008) Qiang Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibroblast adhesion results in the induction of a matrix remodeling gene expression program

(2008) L KENNEDY et al.   MATRIX BIOLOGY

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY