标题
Anticonvulsant neuropeptides as drug leads for neurological diseases
作者
关键词
-
出版物
NATURAL PRODUCT REPORTS
Volume 28, Issue 4, Pages 741
出版商
Royal Society of Chemistry (RSC)
发表日期
2011-02-21
DOI
10.1039/c0np00048e
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Analgesic Neuropeptide W Suppresses Seizures in the Brain Revealed by Rational Repositioning and Peptide Engineering
- (2010) Brad R. Green et al. ACS Chemical Neuroscience
- Anticonvulsant effects and behavioural outcomes of rAAV serotype 1 vector-mediated neuropeptide Y overexpression in rat hippocampus
- (2010) F Noe et al. GENE THERAPY
- Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumours, current aspects and new perspectives
- (2010) Marialuisa Appetecchia et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Identification and Functional Characterization of a Stable, Centrally Active Derivative of the Neurotensin (8−13) Fragment as a Potential First-in-Class Analgesic
- (2010) Francis M. Hughes et al. JOURNAL OF MEDICINAL CHEMISTRY
- Engineering Galanin Analogues That Discriminate between GalR1 and GalR2 Receptor Subtypes and Exhibit Anticonvulsant Activity following Systemic Delivery
- (2010) Charles R. Robertson et al. JOURNAL OF MEDICINAL CHEMISTRY
- GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models
- (2010) X. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions
- (2010) Helena Åkerberg et al. REGULATORY PEPTIDES
- Peptide drugs to target G protein-coupled receptors
- (2010) Kathrin Bellmann-Sickert et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Anticonvulsant Met-Enkephalin Analogues Containing Backbone Spacers Reveal Alternative Non-Opioid Signaling in the Brain
- (2009) Hee-Kyoung Lee et al. ACS Chemical Biology
- Cancer, Chemistry, and the Cell: Molecules that Interact with the Neurotensin Receptors
- (2009) Rebecca M. Myers et al. ACS Chemical Biology
- Lanreotide for the treatment of acromegaly
- (2009) F. Castinetti et al. ADVANCES IN THERAPY
- Which Carbonic Anhydrases are Targeted by the Antiepileptic Sulfonamides and Sulfamates?
- (2009) Giuseppina De Simone et al. Chemical Biology & Drug Design
- Glycosylated Neurotensin Analogues Exhibit Sub-picomolar Anticonvulsant Potency in a Pharmacoresistant Model of Epilepsy
- (2009) Hee-Kyoung Lee et al. ChemMedChem
- Antiepileptic Drugs in Non-Epilepsy Disorders
- (2009) Cecilie Johannessen Landmark CNS DRUGS
- Synthetic therapeutic peptides: science and market
- (2009) Patrick Vlieghe et al. DRUG DISCOVERY TODAY
- Delivering multiple gene products in the brain from a single adeno-associated virus vector
- (2009) S B Foti et al. GENE THERAPY
- Acromegaly pathogenesis and treatment
- (2009) Shlomo Melmed JOURNAL OF CLINICAL INVESTIGATION
- Synthesis and Applications of Polyamine Amino Acid Residues: Improving the Bioactivity of an Analgesic Neuropeptide, Neurotensin
- (2009) Liuyin Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Comparison of N-Terminal Modifications on Neurotensin(8−13) Analogues Correlates Peptide Stability but Not Binding Affinity with in Vivo Efficacy
- (2009) Kevin S. Orwig et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel, Potent, and Radio-Iodinatable Somatostatin Receptor 1 (sst1) Selective Analogues
- (2009) Judit Erchegyi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural Requirements for a Lipoamino Acid in Modulating the Anticonvulsant Activities of Systemically Active Galanin Analogues
- (2009) Liuyin Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Selective and Brain Penetrant Neuropeptide Y Y2 Receptor Antagonists Discovered by Whole-Cell High-Throughput Screening
- (2009) S. P. Brothers et al. MOLECULAR PHARMACOLOGY
- Key factors in the discovery and development of new antiepileptic drugs
- (2009) Meir Bialer et al. NATURE REVIEWS DRUG DISCOVERY
- Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex
- (2009) Luisa Rocha et al. NEUROBIOLOGY OF DISEASE
- Neuropeptide Y: Its multiple effects in the CNS and potential clinical significance
- (2009) E. E. Benarroch NEUROLOGY
- A novel GalR2-specific peptide agonist
- (2009) Johan Runesson et al. NEUROPEPTIDES
- Developing novel antiepileptic drugs: Characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models
- (2009) H. Steve White et al. Neurotherapeutics
- Endogenous opiates and behavior: 2008
- (2009) Richard J. Bodnar PEPTIDES
- Behavioral effects of neuropeptides in rodent models of depression and anxiety
- (2009) Susan Rotzinger et al. PEPTIDES
- 30 years of dynorphins — New insights on their functions in neuropsychiatric diseases
- (2009) Christoph Schwarzer PHARMACOLOGY & THERAPEUTICS
- GPC Receptors and Not Ligands Decide the Binding Mode in Neuropeptide Y Multireceptor/Multiligand System†
- (2008) Diana Lindner et al. BIOCHEMISTRY
- Peptide backbone modifications on the C-terminal hexapeptide of neurotensin
- (2008) Jürgen Einsiedel et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Delivery of peptides to the brain: Emphasis on therapeutic development
- (2008) William A. Banks BIOPOLYMERS
- Neuropeptide Y gene therapy decreases chronic spontaneous seizures in a rat model of temporal lobe epilepsy
- (2008) Francesco Noè et al. BRAIN
- Galanin – 25 years with a multitalented neuropeptide
- (2008) S. E. Counts et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Galanin – 25 years with a multitalented neuropeptide
- (2008) M. R. Picciotto CELLULAR AND MOLECULAR LIFE SCIENCES
- Galanin – 25 years with a multitalented neuropeptide
- (2008) X.-J. Xu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Galanin – 25 years with a multitalented neuropeptide
- (2008) J. N. Crawley CELLULAR AND MOLECULAR LIFE SCIENCES
- Galanin – 25 years with a multitalented neuropeptide
- (2008) K. Mitsukawa et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Galanin – 25 years with a multitalented neuropeptide
- (2008) J. T. Lerner et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Conus Venoms - A Rich Source of Peptide-Based Therapeutics
- (2008) Tiffany Han et al. CURRENT PHARMACEUTICAL DESIGN
- Design, Synthesis, and Characterization of High-Affinity, Systemically-Active Galanin Analogues with Potent Anticonvulsant Activities
- (2008) Grzegorz Bulaj et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Biological Effects of c(Lys-Lys-Pro-Tyr-Ile-Leu-Lys-Lys-Pro-Tyr-Ile-Leu) (JMV2012), a New Analogue of Neurotensin that Crosses the Blood−Brain Barrier
- (2008) Pierre Bredeloux et al. JOURNAL OF MEDICINAL CHEMISTRY
- Neurotensin Enhances GABAergic Activity in Rat Hippocampus CA1 Region by Modulating L-Type Calcium Channels
- (2008) Shanshan Li et al. JOURNAL OF NEUROPHYSIOLOGY
- Somatostatin Receptor Subtype 4 Couples to the M-Current to Regulate Seizures
- (2008) C. Qiu et al. JOURNAL OF NEUROSCIENCE
- Somatostatin: An endogenous antiepileptic
- (2008) Melanie K. Tallent et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Heightened Amygdala Long-Term Potentiation in Neurotensin Receptor Type-1 Knockout Mice
- (2008) Taiju Amano et al. NEUROPSYCHOPHARMACOLOGY
- IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels
- (2008) Anthony J. Harmar et al. NUCLEIC ACIDS RESEARCH
- Molecular recognition of the NPY hormone family by their receptors
- (2008) Diana Lindner et al. NUTRITION
- Endogenous opiates and behavior: 2007
- (2008) Richard J. Bodnar PEPTIDES
- Neuropeptide Y Y2 receptor in health and disease
- (2007) S L Parker et al. BRITISH JOURNAL OF PHARMACOLOGY
- Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse
- (2007) Krisztián Elekes et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Somatostatinergic systems in brain: Networks and functions
- (2007) Cécile Viollet et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
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