Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

Low-Dose Tolerance Is Mediated by the Microfold Cell Ligand, Reovirus Protein  1

(2014) A. Rynda et al.   JOURNAL OF IMMUNOLOGY

Differential Regulation of Chemokines by IL-17 in Colonic Epithelial Cells

(2014) J. W. Lee et al.   JOURNAL OF IMMUNOLOGY

Comprehensive Gene Expression Profiling of Peyer's Patch M Cells, Villous M-Like Cells, and Intestinal Epithelial Cells

(2014) K. Terahara et al.   JOURNAL OF IMMUNOLOGY

Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs

(2014) T. Katakai et al.   JOURNAL OF IMMUNOLOGY

Macrophage Migration Inhibitory Factor Plays a Role in the Regulation of Microfold (M) Cell-Mediated Transport in the Gut

(2014) A. L. Man et al.   JOURNAL OF IMMUNOLOGY

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

Can DCs be distinguished from macrophages by molecular signatures?

(2013) David A Hume et al.   NATURE IMMUNOLOGY

Spi-B is critical for plasmacytoid dendritic cell function and development

(2012) I. Sasaki et al.   BLOOD

M cell targeting by a Claudin 4 targeting peptide can enhance mucosal IgA responses

(2012) David D Lo et al.   BMC BIOTECHNOLOGY

Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion

(2012) Amin Tahoun et al.   Cell Host & Microbe

Jagged1 and Notch1 help edit M cell patterning in Peyer’s patch follicle epithelium

(2012) En-Hui Hsieh et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Identification of Novel Genes Selectively Expressed in the Follicle-Associated Epithelium from the Meta-Analysis of Transcriptomics Data from Multiple Mouse Cell and Tissue Populations

(2012) A. Kobayashi et al.   DNA RESEARCH

Differential intestinal M-cell gene expression response to gut commensals

(2012) Susan Lapthorne et al.   IMMUNOLOGY

Cutting Edge: Brucella abortus Exploits a Cellular Prion Protein on Intestinal M Cells as an Invasive Receptor

(2012) G. Nakato et al.   JOURNAL OF IMMUNOLOGY

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured "Miniguts"

(2012) W. de Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

c-Jun N-Terminal Kinase Phosphorylation of MARCKSL1 Determines Actin Stability and Migration in Neurons and in Cancer Cells

(2012) B. Bjorkblom et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription factor Spi-B–dependent and –independent pathways for the development of Peyer’s patch M cells

(2012) S Sato et al.   Mucosal Immunology

M cell-depletion blocks oral prion disease pathogenesis

(2012) D S Donaldson et al.   Mucosal Immunology

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells

(2012) Takashi Kanaya et al.   NATURE IMMUNOLOGY

Mycobacterium avium subsp. paratuberculosis invades through M cells and enterocytes across ileal and jejunal mucosa of lambs

(2012) Duraisamy Ponnusamy et al.   RESEARCH IN VETERINARY SCIENCE

Annexin A5 Binds to Lipopolysaccharide and Reduces Its Endotoxin Activity

(2012) J. H. Rand et al.   mBio

Distinct Developmental Requirements for Isolated Lymphoid Follicle Formation in the Small and Large Intestine

(2011) Kathryn A. Knoop et al.   AMERICAN JOURNAL OF PATHOLOGY

M cells expressing the complement C5a receptor are efficient targets for mucosal vaccine delivery

(2011) Sae-Hae Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Peyer's Patch Dendritic Cells Sample Antigens by Extending Dendrites Through M Cell-Specific Transcellular Pores

(2011) Hugues Lelouard et al.   GASTROENTEROLOGY

Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages

(2011) Barry M. Bradford et al.   IMMUNOBIOLOGY

CCR6hiCD11cint B cells promote M-cell differentiation in Peyer's patch

(2011) Masashi Ebisawa et al.   INTERNATIONAL IMMUNOLOGY

The Airway Antigen Sampling System: Respiratory M Cells as an Alternative Gateway for Inhaled Antigens

(2011) Dong-Young Kim et al.   JOURNAL OF IMMUNOLOGY

Convergent and Divergent Development among M Cell Lineages in Mouse Mucosal Epithelium

(2011) Jing Wang et al.   JOURNAL OF IMMUNOLOGY

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites

(2011) Pekka Kujala et al.   PLoS Pathogens

Aging impacts isolated lymphoid follicle fevelopment and function

(2011) Keely G McDonald et al.   Immunity & Ageing

CD137 Is Required for M Cell Functional Maturation but Not Lineage Commitment

(2010) En Hui Hsieh et al.   AMERICAN JOURNAL OF PATHOLOGY

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Investigation of lectinized liposomes as M-cell targeted carrier-adjuvant for mucosal immunization

(2010) Prem N. Gupta et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations

(2010) Neil A. Mabbott et al.   IMMUNOBIOLOGY

Mouse Peptidoglycan Recognition Protein PGLYRP-1 Plays a Role in the Host Innate Immune Response againstListeria monocytogenesInfection

(2010) Arihiro Osanai et al.   INFECTION AND IMMUNITY

Peyer's Patch-Deficient Mice Demonstrate That Mycobacterium avium subsp. paratuberculosis Translocates across the Mucosal Barrier via both M Cells and Enterocytes but Has Inefficient Dissemination

(2010) L. E. Bermudez et al.   INFECTION AND IMMUNITY

The M Cell-Targeting Ligand Promotes Antigen Delivery and Induces Antigen-Specific Immune Responses in Mucosal Vaccination

(2010) S.-H. Kim et al.   JOURNAL OF IMMUNOLOGY

Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo

(2010) Sayuri Chiba et al.   MICROBIOLOGY AND IMMUNOLOGY

Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

(2010) C. Lopez-Garcia et al.   SCIENCE

Toll-like receptor 5- and lymphotoxin β receptor-dependent epithelial Ccl20 expression involves the same NF-κB binding site but distinct NF-κB pathways and dynamics

(2009) Jean-Claude Sirard et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

TNFR and LTβR agonists induce follicle-associated epithelium and M cell specific genes in rat and human intestinal epithelial cells

(2009) Jing Wang et al.   CYTOKINE

New Approach for M-Cell-Specific Molecules Screening by Comprehensive Transcriptome Analysis

(2009) G. Nakato et al.   DNA RESEARCH

Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer’s patches and epithelial M cells of mouse intestine

(2009) Ryoji Suzuki et al.   HISTOCHEMISTRY AND CELL BIOLOGY

M-Cell Targeting of Whole Killed Bacteria Induces Protective Immunity against Gastrointestinal Pathogens

(2009) Y.-T. Chionh et al.   INFECTION AND IMMUNITY

Claudin 4-targeted protein incorporated into PLGA nanoparticles can mediate M cell targeted delivery

(2009) Thejani E. Rajapaksa et al.   JOURNAL OF CONTROLLED RELEASE

RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

(2009) K. A. Knoop et al.   JOURNAL OF IMMUNOLOGY

Secretory IgA-Mediated Neutralization of Shigella flexneri Prevents Intestinal Tissue Destruction by Down-Regulating Inflammatory Circuits

(2009) S. Boullier et al.   JOURNAL OF IMMUNOLOGY

The Effects of Host Age on Follicular Dendritic Cell Status Dramatically Impair Scrapie Agent Neuroinvasion in Aged Mice

(2009) K. L. Brown et al.   JOURNAL OF IMMUNOLOGY

Targeted Delivery of Immunogen to Primate M Cells with Tetragalloyl Lysine Dendrimer

(2009) Shogo Misumi et al.   JOURNAL OF IMMUNOLOGY

Effect of age on susceptibility to Salmonella Typhimurium infection in C57BL/6 mice

(2009) Z. Ren et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa

(2009) K Kotarsky et al.   Mucosal Immunology

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

(2009) Koji Hase et al.   NATURE CELL BIOLOGY

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

(2009) Weifeng Xu et al.   NATURE IMMUNOLOGY

Resistance of Chemokine Receptor 6-Deficient Mice to Yersinia Enterocolitica Infection

(2008) Sabine Westphal et al.   AMERICAN JOURNAL OF PATHOLOGY

Nonhuman primate intestinal villous M-like cells: An effective poliovirus entry site

(2008) Yoshihiro Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

(2008) E.A. Eugenin et al.   CELLULAR IMMUNOLOGY

Ovalbumin-Protein σ1 M-Cell Targeting Facilitates Oral Tolerance With Reduction of Antigen-Specific CD4+ T Cells

(2008) Hideaki Suzuki et al.   GASTROENTEROLOGY